Prof. Dr. Meike Stiesch participates in RESIST research projects C1 and C2.
| My Research Interest in RESIST |
Our major scientific interest in RESIST is the investigation of mechanisms of biofilm formation and resistance in patients with biofilm-associated periimplant infections. The long-term goal is the identification of biomarkers for periimplant infections and the development of new diagnostic systems and effective intervention strategies for the control of these chronic infections.
In pursuing this research programme, we build on our longterm experience with biofilm-associated periimplant infections and our Europe wide collection of biofilms, implants and implant-associated human tissues (Biobank). We have established innovative biofilm model systems that allow for the investigation of new anti-biofilm strategies in vitro, in vivo and in silico. Over the course of the next 6 years we want to gain new insights into biofilm resistance mechanisms that have the potential to discover new and promising targets for diagnostics and effective anti-biofilm therapies.
Prof. Stiesch and Dr. Jörn Schaeske
Prof. Dr. Meike Stiesch – Curriculum Vitae
Current Position
Undergraduate and Postgraduate Training
Academic and Research Posts
Other Scientific Roles
Awards and Prizes
10 Selected Publications (of > 250 original publications)
Ingendoh-Tsakmakidis A, Mikolai C, Winkel A, Szafrański SP, Falk CS, Rossi A, Walles H, Stiesch M. Commensal and pathogenic biofilms differently modulate peri-implant oral mucosa in an organotypic model. Cell Microbiol. 2019 Jul 3:e13078. doi: 10.1111/cmi.13078.
Szafrański SP, Kilian M, Yang I, Bei der Wieden G, Winkel A, Hegermann J, Stiesch M. Diversity patterns of bacteriophages infecting Aggregatibacter and Haemophilus species across clades and niches. ISME J. 2019 Jun 14. doi: 10.1038/s41396-019-0450-8.
Doll K, Yang I, Fadeeva E, Kommerein N, Szafrański SP, Bei der Wieden G, Greuling A, Winkel A, Chichkov BN, Stumpp NS, Stiesch M. Liquid-Infused Structured Titanium Surfaces: Antiadhesive Mechanism to Repel Streptococcus oralis Biofilms. ACS Appl Mater Interfaces. 2019 Jul 3;11(26):23026-23038. doi: 10.1021/acsami.9b06817.
Ingendoh-Tsakmakidis A, Nolte L, Winkel A, Meyer H, Koroleva A, Shpichka A, Ripken T, Heisterkamp A, Stiesch M. Time resolved 3D live-cell imaging on implants. PLoS One. 2018; doi: 10.1371.
Dreyer H, Grischke J, Tiede C, Eberhard J, Schweitzer A, Toikkanen SE, Glöckner S, Krause G, Stiesch M. Epidemiology and risk factors of peri- implantitis: A systematic review. J Periodontal Res. 2018; doi: 10.1111/jre.12562. (Epub ahead of print)
Kommerein N, Doll K, Stumpp NS, Stiesch M. Development and characterization of an oral multispecies biofilm implant flow chamber model. PLoS One. 2018; 5: doi: 10.1371
Doll K, Fadeeva E, Schaeske J, Ehmke T, Winkel A, Heisterkamp A, Chichkov BN, Stiesch M, Stumpp NS. Development of laser-structured liquid-infused titanium with strong biofilm-repellent properties. ACS Appl Mater Interfaces. 2017; 11: 9359-9368.
Kommerein N, Stumpp SN, Müsken M, Ehlert N, Winkel A, Häussler S, Behrens P, Buettner FF, Stiesch M. An oral multispecies biofilm model for high content screening applications. PLoS One 2017;12: e0173973.
Rath H, Feng D, Neuweiler I, Stumpp NS, Nackenhorst U, Stiesch M. Biofilm formation by the oral pioneer colonizer Streptococcus gordonii: an experimental and numerical study. FEMS Microbiol Ecol 2017; 93.
Szafrański SP, Winkel A, Stiesch M. The use of bacteriophages to biocontrol oral biofilms. J Biotechnol. 2017; 250:29-44.
