Publikations-Highlights

Die hier genannten Veröffentlichungen zeigen besonders hervorzuhebende aktuelle Ergebnisse unserer exzellenten Forschung.

Broadly neutralizing antibodies isolated from HEV convalescents confer protective effects in human liver-chimeric mice.

Ssebyatika, G., K. Dinkelborg, L. J. Ströh, F. Hinte, L. Corneillie, L. Hueffner, E. M. Guzman, P. L. Nankya, N. Plückebaum, L. Fehlau, J. Garn, N. Meyer, S. Prallet, A. K. Mehnert, A. R. M. Kraft, L. Verhoye, C. Jacobsen, E. Steinmann, H. Wedemeyer, A. Viejo-Borbolla, V. L. Dao Thi, T. Pietschmann, M. Lütgehetmann, P. Meuleman, M. Dandri, T. Krey, and P. Behrendt.
Nat Commun

Giant RNA genomes: Roles of host, translation elongation, genome architecture, and proteome in nidoviruses.

Neuman, B. W., A. Smart, O. Gilmer, R. P. Smyth, J. Vaas, N. Böker, D. V. Samborskiy, R. Bartenschlager, S. Seitz, A. E. Gorbalenya, N. Caliskan, and C. Lauber.
Proc Natl Acad Sci

Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination.

Li, W., Z. Zhang, S. Kumar, J. Botey-Bataller, M. Zoodsma, A. Ehsani, Q. Zhan, A. Alaswad, L. Zhou, I. Grondman, V. Koeken, J. Yang, G. Wang, S. Volland, T. O. Crişan, L. A. B. Joosten, T. Illig, C. J. Xu, M. G. Netea, and Y. Li.
Nat Aging.

Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth.

Ehlers, G., A. M. Tödtmann, L. Holsten, M. Willers, J. Heckmann, J. Schöning, M. Richter, A. S. Heinemann, S. Pirr, A. Heinz, C. Dopfer, K. Händler, M. Becker, J. Büchel, A. Wöckel, C. von Kaisenberg, G. Hansen, K. Hiller, J. L. Schultze, C. Härtel, W. Kastenmüller, M. Vaeth, T. Ulas, and D. Viemann.
Nat Commun

Ausgewählte RESIST-Publikationen

Hier finden Sie Publikationen von RESIST-Forscherinnen und Forschern.
  1. Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition. Wang J, Brückner N, Weissmann S, Günther T, Zhu S, Vogt C, Sun G, Guo R, Bruno R, Ritter B, Steinbrück L, Kaufer BB, Depledge DP, Grundhoff A, Viejo-Borbolla A. PLoS Pathog. 2025 Feb 10;21(2):e1012367. doi: 10.1371/journal.ppat.1012367. Epub ahead of print. PMID: 39928684.
  2. The effect of HLA genotype on disease onset and severity in CTLA-4 insufficiency
    S. Posadas-Cantera, N. Mitsuiki, F. Emmerich, V. Patiño, H. M. Lorenz, O. Neth, et al. Front Immunol 2025 Vol. 15 Pages 1447995 Accession Number: 39835139 PMCID: PMC11744039 DOI: 10.3389/fimmu.2024.1447995
  3. Influenza Immunization in Very-Low-Birth-Weight Infants: Epidemiology and Long-Term Outcomes M. T. Dammann, H. Kraft, G. Stichtenoth, K. Hanke, M. Zemlin, J. Soler Wenglein, et al. Vaccines (Basel) 2025 Vol. 13 Issue 1 Accession Number: 39852821 PMCID: PMC11769184 DOI: 10.3390/vaccines13010042
  4. A corpus of GA4GH phenopackets: Case-level phenotyping for genomic diagnostics and discovery D. Danis, M. J. Bamshad, Y. Bridges, A. Caballero-Oteyza, P. Cacheiro, L. C. Carmody, et al. HGG Adv 2025 Vol. 6 Issue 1 Pages 100371 Accession Number: 39394689 PMCID: PMC11564936 DOI: 10.1016/j.xhgg.2024.100371
  5. Identification of optimal portal pressure decrease to control ascites while minimizing hepatic encephalopathy after TIPS: A multicenter study M. A. Kabelitz, L. Hartl, G. Schaub, A. Tiede, H. Rieland, A. Kornfehl, et al. Hepatology 2025 Accession Number: 39773850 DOI: 10.1097/hep.0000000000001219
  6. Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traits L. Riemann, R. Gutierrez, I. Odak, J. Barros-Martins, L. M. Roesner, X. Leon Lara, et al. EBioMedicine 2025 Vol. 112 Pages 105558 Accession Number: 39862806 DOI: 10.1016/j.ebiom.2025.105558
  7. Comparison of clinical outcomes in patients with refractory ascites treated with either TIPS, tunneled peritoneal catheter, or ascites pump S. L. Schütte, A. Tiede, J. B. Mauz, H. Rieland, M. Kabelitz, R. Iker, et al. Hepatol Commun 2025 Vol. 9 Issue 2 Accession Number: 39813591 PMCID: PMC11737501 DOI: 10.1097/hc9.0000000000000620
  8. A clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI) C. R. Hartmann, R. Khan, J. Schöning, M. Richter, M. Willers, S. Pirr, et al. Front Immunol 2024 Vol. 15 Pages 1443665 Accession Number: 39355253 PMCID: PMC11442434 DOI: 10.3389/fimmu.2024.1443665
  9. Editorial: Stopping NUCs-When to Restart NUCs for the Best Outcome? M. Urbanek-Quaing and M. Cornberg Aliment Pharmacol Ther 2025 Vol. 61 Issue 1 Pages 204-205 Accession Number: 39499186 DOI: 10.1111/apt.18370
  10. Ablation of the deubiquitinating enzyme cylindromatosis (CYLD) augments STAT1-mediated M1 macrophage polarization and fosters Staphylococcus aureus control C. Schmidt, K. Harit, S. Traidl, M. Naumann, T. Werfel, L. M. Roesner, et al. Front Immunol 2025 Vol. 16 Pages 1507989 Accession Number: 39958342 PMCID: PMC11827430 DOI: 10.3389/fimmu.2025.1507989
  11. TIGIT-expression on natural killer cell subsets is an early indicator of alleviating liver inflammation following bulevirtide treatment in chronic hepatitis D P. C. Chen, K. Deterding, S. A. Engelskircher, K. Port, L. Sandmann, A. Chakkadath, et al. Hepatology 2025 Accession Number: 39847437 DOI: 10.1097/hep.0000000000001238
  12. Phase 2 Randomised Study of Bulevirtide as Monotherapy or Combined With Peg-IFNα-2a as Treatment for Chronic Hepatitis Delta P. Lampertico, P. O. Bogomolov, V. Chulanov, T. Stepanova, V. Morozov, L. Allweiss, et al. Liver Int 2025 Vol. 45 Issue 2 Pages e70008 Accession Number: 39853842 PMCID: PMC11760647 DOI: 10.1111/liv.70008
  13. Value and Kinetics of Virological Markers in the Natural Course of Chronic Hepatitis D Virus Infection L. Sandmann, V. Ohlendorf, A. Ehrenbauer, B. Bremer, A. R. M. Kraft, M. Cornberg, et al. Liver Int 2025 Vol. 45 Issue 2 Pages e70003 Accession Number: 39846714 PMCID: PMC11756344 DOI: 10.1111/liv.70003
  14. microGWAS: a computational pipeline to perform large-scale bacterial genome-wide association studies J. Burgaya, B. F. Damaris, J. Fiebig and M. Galardini Microb Genom 2025 Vol. 11 Issue 2 Accession Number: 39932497 DOI: 10.1099/mgen.0.001349
  15. Identification and characterization of the functional tetrameric UDP-glucose pyrophosphorylase from Klebsiella pneumoniae I. Ramón Roth, P. Kats, T. Fiebig, F. Routier, R. Fedorov, L. Dirr, et al. mBio 2025 Vol. 16 Issue 2 Pages e0207124 Accession Number: 39704542 PMCID: PMC11796359 DOI: 10.1128/mbio.02071-24
  16. Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections A. Shekhar, R. Di Lucrezia, K. Jerye, V. S. Korotkov, K. Harmrolfs, K. Rox, et al. Cell Host Microbe 2025 Accession Number: 40168998 DOI: 10.1016/j.chom.2025.03.006
  17. Combinatorial Fc modifications for complementary antibody functionality Y. C. Bartsch, N. E. Webb, E. Burgess, J. Kang, D. A. Lauffenburger and B. D. Julg MAbs 2025 Vol. 17 Issue 1 Pages 2465391 Accession Number: 39950649 PMCID: PMC11834420 DOI: 10.1080/19420862.2025.2465391
  18. Dysphoric Milk Ejection Reflex: Prevalence, persistence, and implications R. Cappenberg, J. G. Garcia, I. Liolios, C. Happle and A. Zychlinsky Scharff Eur J Obstet Gynecol Reprod Biol 2025 Vol. 308 Pages 127-131 Accession Number: 40043530 DOI: 10.1016/j.ejogrb.2025.02.051
  19. Molecular mechanisms of hotspot variants in cytoskeletal β-actin associated with Baraitser-Winter syndrome  J. N. Greve and D. J. Manstein Febs j 2025 Accession Number: 39930656 DOI: 10.1111/febs.70018
  20. Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination W. Li, Z. Zhang, S. Kumar, J. Botey-Bataller, M. Zoodsma, A. Ehsani, et al. Nat Aging 2025 Accession Number: 40044970 DOI: 10.1038/s43587-025-00819-z
  21. Acsbg1 regulates differentiation and inflammatory properties of CD4+ T cells M. Palatella, F. Kruse, S. Glage, A. Bleich, M. Greweling-Pils and J. Huehn Eur J Microbiol Immunol (Bp) 2025 Accession Number: 39937199 DOI: 10.1556/1886.2025.00003
  22. Distinctive CD8(+) T cell activation by antigen-presenting plasmacytoid dendritic cells compared to conventional dendritic cells R. M. van der Sluis, J. L. García-Rodríguez, I. H. Nielsen, A. Gris-Oliver, J. Becker, B. Costa, et al. Cell Rep 2025 Vol. 44 Issue 3 Pages 115413 Accession Number: 40073016 DOI: 10.1016/j.celrep.2025.115413
  23. TIPS insertion and systemic inflammation: Is it ever too late to lower portal pressure? A. Tiede and B. Maasoumy Clin Mol Hepatol 2025 Accession Number: 39925001 DOI: 10.3350/cmh.2025.0135
  24. Broadly neutralizing antibodies isolated from HEV convalescents confer protective effects in human liver-chimeric mice G. Ssebyatika, K. Dinkelborg, L. J. Ströh, F. Hinte, L. Corneillie, L. Hueffner, et al. Nat Commun 2025 Vol. 16 Issue 1 Pages 1995 Accession Number: 40011441 DOI: 10.1038/s41467-025-57182-1
  25. Reappraisal of IgG subclass deficiencies: a retrospective comparative cohort study D. Dogru, Y. Dogru, F. Atschekzei, A. Elsayed, N. Dubrowinskaja, D. Ernst, et al. Front Immunol 2025 Vol. 16 Pages 1552513 Accession Number: 40313941 PMCID: PMC12043879 DOI: 10.3389/fimmu.2025.1552513
  26. A novel hemizygous nonsense variant in DOCK11 causes systemic inflammation and immunodeficiency A. Elsayed, S. von Hardenberg, F. Atschekzei, P. Siek, T. Witte, G. Sogkas, et al. Clin Immunol 2025 Vol. 276 Pages 110504 Accession Number: 40274249 DOI: 10.1016/j.clim.2025.110504
  27. A precision medicine approach to primary immunodeficiency disease: Ataluren strikes nonsense mutations once again L. Lentini, R. Perriera, F. Corrao, R. Melfi, M. Tutone, P. S. Carollo, et al. Mol Ther 2025 Accession Number: 40158206 DOI: 10.1016/j.ymthe.2025.03.045
  28. The intestinal microbiome and metabolome discern disease severity in cytotoxic T-lymphocyte-associated protein 4 deficiency P. Chandrasekaran, M. Krausz, Y. Han, N. Mitsuiki, A. Gabrysch, C. Nöltner, et al. Microbiome 2025 Vol. 13 Issue 1 Pages 51 Accession Number: 39934899 PMCID: PMC11817180 DOI: 10.1186/s40168-025-02028-7
  29. Bruton’s tyrosine kinase (BTK) and matrix metalloproteinase-9 (MMP-9) regulate NLRP3 inflammasome-dependent cytokine and neutrophil extracellular trap responses in primary neutrophils V. N. C. Leal, F. Bork, M. Mateo Tortola, J. C. von Guilleaume, C. L. Greve, S. Bugl, et al. J Allergy Clin Immunol 2025 Vol. 155 Issue 2 Pages 569-582 Accession Number: 39547282 DOI: 10.1016/j.jaci.2024.10.035
  30. Unlocking the antiviral arsenal: Structure-guided optimization of small-molecule inhibitors against RSV and hCoV-229E C. Karhan, S. M. Sake, A. P. Gunesch, C. Grethe, B. Hellwinkel, N. M. Köhler, et al. Eur J Med Chem 2025 Vol. 291 Pages 117282 Accession Number: 40199027 DOI: 10.1016/j.ejmech.2025.117282
  31. Long-term histone lactylation connects metabolic and epigenetic rewiring in innate immune memory A. Ziogas, B. Novakovic, L. Ventriglia, N. Galang, K. A. Tran, W. Li, et al. Cell 2025 Accession Number: 40318634 DOI: 10.1016/j.cell.2025.03.048
  32. Transmissible Staphylococcus pseudintermedius thwarts neutrophil extracellular trap-driven containment to promote invasive disease R. Haller, Y. Cai, N. de Buhr, J. C. Rieder, D. Schlüter, C. Baier, et al. Emerg Microbes Infect 2025 Vol. 14 Issue 1 Pages 2482709 Accession Number: 40172876 PMCID: PMC12001851 DOI: 10.1080/22221751.2025.2482709
  33. Using structure-function information from IFN-γ-binding proteins and biased agonists to uncouple immunostimulatory and immunosuppressive activities L. Mendes-Monteiro and A. Viejo-Borbolla Trends Immunol 2025 Accession Number: 40102163 DOI: 10.1016/j.it.2025.02.013
  34. Giant RNA genomes: Roles of host, translation elongation, genome architecture, and proteome in nidoviruses B. W. Neuman, A. Smart, O. Gilmer, R. P. Smyth, J. Vaas, N. Böker, et al. Proc Natl Acad Sci U S A 2025 Vol. 122 Issue 7 Pages e2413675122 Accession Number: 39928875 PMCID: PMC11848433 DOI: 10.1073/pnas.2413675122
  35. Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth G. Ehlers, A. M. Tödtmann, L. Holsten, M. Willers, J. Heckmann, J. Schöning, et al. Nat Commun 2025 Vol. 16 Issue 1 Pages 2239 Accession Number: 40050264 PMCID: PMC11885822 DOI: 10.1038/s41467-025-57357-w
  36. The neonate respiratory microbiome S. Pirr, M. Willers and D. Viemann Acta Physiol (Oxf) 2025 Vol. 241 Issue 2 Pages e14266Accession Number: 39840649 PMCID: PMC11752418 DOI: 10.1111/apha.14266
  37. Distinct clusters of bacterial and fungal microbiota in end-stage liver cirrhosis correlate with antibiotic treatment, intestinal barrier impairment, and systemic inflammation L. Buttler, D. A. Velázquez-Ramírez, A. Tiede, A. M. Conradi, S. Woltemate, R. Geffers, et al. Gut Microbes 2025 Vol. 17 Issue 1 Pages 2487209 Accession Number: 40255076 DOI: 10.1080/19490976.2025.2487209
  38. Reply: Refining epigenetic insights in HBV-Specific T Cell restoration Y. H. Chou and M. Cornberg Hepatology 2025 Accession Number: 40168461 DOI: 10.1097/hep.0000000000001340
  39. Limited Value of HBV-RNA for Relapse Prediction After Nucleos(t)ide Analogue Withdrawal in HBeAg-negative Hepatitis B Patients V. Ohlendorf, M. Wübbolding, C. Höner Zu Siederdissen, B. Bremer, K. Deterding, H. Wedemeyer, et al. J Viral Hepat 2025 Vol. 32 Issue 4 Pages e14026 Accession Number: 39425534 PMCID: PMC11887418 DOI: 10.1111/jvh.14026
  40. Sequence analysis of the hepatitis D virus across genotypes reveals highly conserved regions amidst evidence of recombination S. Chowdhury, C. Jacobsen, D. P. Depledge, H. Wedemeyer, L. Sandmann and H. Kefalakes Virus Evol 2025 Vol. 11 Issue 1 Pages veaf012 Accession Number: 40123834 PMCID: PMC11927530 DOI: 10.1093/ve/veaf012
  41. A novel in vitro system for simultaneous infections with hepatitis B, C, D and E viruses R. Fouillé, E. R. Verrier, A. De Meyer, L. Verhoye, M. Michelet, R. Barnault, et al JHEP Rep 2025 Vol. 7 Issue 5 Pages 101383 Accession Number: 40242313 PMCID: PMC11999259 DOI: 10.1016/j.jhepr.2025.101383
  42. Frequency, Severity and Impact of Pegylated Interferon Alpha-Associated Flares in Hepatitis D Infection S. Hardtke, C. Yurdaydin, F. A. Caruntu, M. G. Curescu, K. Yalcin, U. S. Akarca, et al. J Viral Hepat 2025 Vol. 32 Issue 4 Pages e70022 Accession Number: 40087915 PMCID: PMC11909584 DOI: 10.1111/jvh.70022
  43. Establishment and characterization of persistent Pseudomonas aeruginosa infections in air-liquid interface cultures of human airway epithelial cells S. Bouheraoua, S. Cleeves, M. Preusse, M. Müsken, P. Braubach, M. Fuchs, et al. Infect Immun 2025 Pages e0060324 Accession Number: 39964154 DOI: 10.1128/iai.00603-24
  44. Profiling the nasopharyngeal Microbiome in patients with community-acquired pneumonia caused by Streptococcus pneumoniae: diagnostic challenges and ecological insights C. Zubiria-Barrera, L. Y. Yamba, T. E. Klassert, M. Bos, J. Ahl, L. Wasserstrom, et al. Med Microbiol Immunol 2025 Vol. 214 Issue 1 Pages 19 Accession Number: 40208342 PMCID: PMC11985632 DOI: 10.1007/s00430-025-00828-0
  45. Profiling the nasopharyngeal Microbiome in patients with community-acquired pneumonia caused by Streptococcus pneumoniae: diagnostic challenges and ecological insights C. Zubiria-Barrera, L. Y. Yamba, T. E. Klassert, M. Bos, J. Ahl, L. Wasserstrom, et al. Med Microbiol Immunol 2025 Vol. 214 Issue 1 Pages 19 Accession Number: 40208342 PMCID: PMC11985632 DOI: 10.1007/s00430-025-00828-0
  46. Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria E. Cacace, M. Tietgen, M. Steinhauer, A. Mateus, T. G. Schultze, M. Eckermann, et al. Nat Commun 2025 Vol. 16 Issue 1 Pages 3783 Accession Number: 40263263 DOI: 10.1038/s41467-025-58730-5
  47. Interaction of human cytomegalovirus pUL52 with major components of the viral DNA encapsidation network underlines its essential role in genome cleavage-packaging S. Harmening, B. Bogdanow, K. Wagner, F. Liu, M. Messerle and E. M. Borst J Virol 2025 Pages e0220124 Accession Number: 40062846 DOI: 10.1128/jvi.02201-24
  48. Herpes simplex virus assembly and spread in murine skin after infection from the outside T. Richardo, X. Liu, K. Döhner, T. Y. Chao, A. Buch, A. Binz, et al. J Virol 2025 Pages e0163824 Accession Number: 39945537 DOI: 10.1128/jvi.01638-24
  49. Adenovirus E1B-55K interferes with cellular IκB kinase complex subunit proteins W. H. Ip, L. D. Bertzbach, S. Schreiner and T. Dobner Front Immunol 2025 Vol. 16 Pages 1532742 Accession Number: 40103806 PMCID: PMC11913716 DOI: 10.3389/fimmu.2025.1532742
  1. Abnormal biomarkers predict complex FAS or FADD defects missed by exome sequencing. Rensing-Ehl A, Lorenz MR, Führer M, Willenbacher W, Willenbacher E, Sopper S, Abinun M, Maccari ME, König C, Haegele P, Fuchs S, Castro C, Kury P, Pelle O, Klemann C, Heeg M, Thalhammer J, Wegehaupt O, Fischer M, Goldacker S, Schulte B, Biskup S, Chatelain P, Schuster V, Warnatz K, Grimbacher B, Meinhardt A, Holzinger D, Oommen PT, Hinze T, Hebart H, Seeger K, Lehmberg K, Leahy TR, Claviez A, Vieth S, Schilling FH, Fuchs I, Groß M, Rieux-Laucat F, Magerus A, Speckmann C, Schwarz K, Ehl S; ALPS Study Group.  J Allergy Clin Immunol. 2024 Jan;153(1):297-308.e12. doi: 10.1016/j.jaci.2023.11.006. Epub 2023 Nov 17. PMID: 37979702.
  2. CAR macrophages on a fast track to solid tumor therapy.  Abdin SM, Paasch D, Lachmann N. Nat Immunol. 2024 Jan;25(1):11-12. doi: 10.1038/s41590-023-01696-7. PMID: 38168956.
  3. Epigenetic immune cell quantification for diagnostic evaluation and monitoring of patients with inborn errors of immunity and secondary immune deficiencies. Ramirez NJ, Schulze JJ, Walter S, Werner J, Mrovecova P, Olek S, Sachsenmaier C, Grimbacher B, Salzer U.  Clin Immunol. 2024 Mar;260:109920. doi: 10.1016/j.clim.2024.109920. Epub 2024 Feb 1. PMID: 38307474.
  4. Humoral and cellular immune responses following BNT162b2 XBB.1.5 vaccination. Stankov MV, Hoffmann M, Gutierrez Jauregui R, Cossmann A, Morillas Ramos G, Graalmann T, Winter EJ, Friedrichsen M, Ravens I, Ilievska T, Ristenpart J, Schimrock A, Willenzon S, Ahrenstorf G, Witte T, Förster R, Kempf A, Pöhlmann S, Hammerschmidt SI, Dopfer-Jablonka A, Behrens GMN.  Lancet Infect Dis. 2024 Jan;24(1):e1-e3. doi: 10.1016/S1473-3099(23)00690-4. Epub 2023 Nov 20. PMID: 37995739.
  5. Ten-year experience of whole lung lavage in pediatric Pulmonary Alveolar Proteinosis. Nickel K, Schütz K, Carlens J, Grewendorf S, Wetzke M, Keil O, Dennhardt N, Rigterink V, Köditz H, Sasse M, Happle C, Beck CE, Schwerk N.  Klin Padiatr. 2024 Feb;236(2):64-72. doi: 10.1055/a-2194-3467. Epub 2024 Jan 23. PMID: 38262422; PMCID: PMC10883753.
  6. The Challenge of Anticoagulation in Liver Cirrhosis. Eichholz JC, Wedemeyer H, Maasoumy B.  Visc Med. 2024 Jan;39(6):169-176. doi: 10.1159/000535438. Epub 2023 Dec 21. PMID: 38205270; PMCID: PMC10775854.
  7. The effector program of human CD8 T cells supports tissue remodeling. Delacher M, Schmidleithner L, Simon M, Stüve P, Sanderink L, Hotz-Wagenblatt A, Wuttke M, Schambeck K, Ruhland B, Hofmann V, Bittner S, Ritter U, Pant A, Helbich SS, Voss M, Lemmermann NA, Bessiri-Schake L, Bohn T, Eigenberger A, Menevse AN, Gebhard C, Strieder N, Abken H, Rehli M, Huehn J, Beckhove P, Hehlgans T, Junger H, Geissler EK, Prantl L, Werner JM, Schmidl C, Brors B, Imbusch CD, Feuerer M.  J Exp Med. 2024 Feb 5;221(2):e20230488. doi: 10.1084/jem.20230488. Epub 2024 Jan 16. PMID: 38226976; PMCID: PMC10791561.
  8. E4orf1: The triple agent of adenovirus – Unraveling its roles in oncogenesis, infectious obesity and immune responses in virus replication and vector therapy. Göttig L, Schreiner S. Tumour Virus Res. 2024 Feb 28:200277. doi: 10.1016/j.tvr.2024.200277. Online ahead of print. PMID: 38428735 Review.
  9. Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells. Costa B, Becker J, Krammer T, Mulenge F, Durán V, Pavlou A, Gern OL, Chu X, Li Y, Čičin-Šain L, Eiz-Vesper B, Messerle M, Dölken L, Saliba AE, Erhard F, Kalinke U. Nat Commun. 2024 Feb 26;15(1):1745. doi: 10.1038/s41467-024-45614-3. PMID: 38409141 Free PMC article.
  10. Pulmonary Alveolar Proteinosis and new therapeutic concepts. Rodriguez Gonzalez C, Schevel H, Hansen G, Schwerk N, Lachmann N.
    Klin Padiatr. 2024 Feb;236(2):73-79. doi: 10.1055/a-2233-1243. Epub 2024 Jan 29. PMID: 38286410 Free PMC article.
  11. Pulmonary Alveolar Proteinosis and new therapeutic concepts. Rodriguez Gonzalez, C., H. Schevel, G. Hansen, N. Schwerk, and N. Lachmann. 2024.  Klin Padiatr. 236: e1.
  12. Crystal structure of the tegument protein UL82 (pp71) from human cytomegalovirus. Eberhage J, Bresch IP, Ramani R, Viohl N, Buchta T, Rehfeld CL, Hinse P, Reubold TF, Brinkmann MM, Eschenburg S. Protein Sci. 2024 Mar;33(3):e4915. doi: 10.1002/pro.4915. PMID: 38358250
  13. Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. Sake SM, Zhang X, Rajak MK, Urbanek-Quaing M, Carpentier A, Gunesch AP, Grethe C, Matthaei A, Rückert J, Galloux M, Larcher T, Le Goffic R, Hontonnou F, Chatterjee AK, Johnson K, Morwood K, Rox K, Elgaher WAM, Huang J, Wetzke M, Hansen G, Fischer N, Eléouët JF, Rameix-Welti MA, Hirsch AKH, Herold E, Empting M, Lauber C, Schulz TF, Krey T, Haid S, Pietschmann T. Nat Commun. 2024 Feb 8;15(1):1173. doi: 10.1038/s41467-024-45241-y. PMID: 38332002 Free PMC article.
  14. Unraveling the dynamics of hepatitis C virus adaptive mutations and their impact on antiviral responses in primary human hepatocytes. Frericks N, Brown RJP, Reinecke BM, Herrmann M, Brüggemann Y, Todt D, Miskey C, Vondran FWR, Steinmann E, Pietschmann T, Sheldon J. J Virol. 2024 Feb 6:e0192123. doi: 10.1128/jvi.01921-23. Online ahead of print. PMID: 38319104
  15. Anti-CRISPR Anopheles mosquitoes inhibit gene drive spread under challenging behavioural conditions in large cages. D’Amato R, Taxiarchi C, Galardini M, Trusso A, Minuz RL, Grilli S, Somerville AGT, Shittu D, Khalil AS, Galizi R, Crisanti A, Simoni A, Müller R. Nat Commun. 2024 Feb 1;15(1):952. doi: 10.1038/s41467-024-44907-x. PMID: 38296981
  16. Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection. Sun G, Kropp KA, Kirchner M, Plückebaum N, Selich A, Serrero M, Dhingra A, Cabrera JR, Ritter B, Bauerfeind R, Wyler E, Landthaler M, Schambach A, Sodeik B, Mertins P, Viejo-Borbolla A. mBio. 2024 Jan 26:e0330823. doi: 10.1128/mbio.03308-23. Online ahead of print. PMID: 38275838
  17. CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells. Hammad R, Alzubi J, Rhiel M, Chmielewski KO, Mosti L, Rositzka J, Heugel M, Lawrenz J, Pennucci V, Gläser B, Fischer J, Schambach A, Moritz T, Lachmann N, Cornu TI, Mussolino C, Schäfer R, Cathomen T. Int J Mol Sci. 2024 Jan 12;25(2):985. doi: 10.3390/ijms25020985. PMID: 38256061
  18. Human inherited CCR2 deficiency underlies progressive polycystic lung disease. Neehus AL, Carey B, Landekic M, Panikulam P, Deutsch G, Ogishi M, Arango-Franco CA, Philippot Q, Modaresi M, Mohammadzadeh I, Corcini Berndt M, Rinchai D, Le Voyer T, Rosain J, Momenilandi M, Martin-Fernandez M, Khan T, Bohlen J, Han JE, Deslys A, Bernard M, Gajardo-Carrasco T, Soudée C, Le Floc’h C, Migaud M, Seeleuthner Y, Jang MS, Nikolouli E, Seyedpour S, Begueret H, Emile JF, Le Guen P, Tavazzi G, Colombo CNJ, Marzani FC, Angelini M, Trespidi F, Ghirardello S, Alipour N, Molitor A, Carapito R, Mazloomrezaei M, Rokni-Zadeh H, Changi-Ashtiani M, Brouzes C, Vargas P, Borghesi A, Lachmann N, Bahram S, Crestani B, Pahari S, Schlesinger LS, Marr N, Bugonovic D, Boisson-Dupuis S, Béziat V, Abel L, Borie R, Young LR, Deterding R, Shahrooei M, Rezaei N, Parvaneh N, Craven D, Gros P, Malo D, Sepulveda FE, Nogee LM, Aladjidi N, Trapnell BC, Casanova JL, Bustamante J. Cell. 2024 Jan 18;187(2):390-408.e23. doi: 10.1016/j.cell.2023.11.036. Epub 2023 Dec 28. PMID: 38157855
  19. Clean Synthetic Strategies to Biologically Active Molecules from Lignin: A Green Path to Drug Discovery. Afanasenko AM, Wu X, De Santi A, Elgaher WAM, Kany AM, Shafiei R, Schulze MS, Schulz TF, Haupenthal J, Hirsch AKH, Barta K. Angew Chem Int Ed Engl. 2024 Jan 22;63(4):e202308131. doi: 10.1002/anie.202308131. Epub 2023 Nov 14. PMID: 37840425
  20. A tetravalent bispecific antibody outperforms the combination of its parental antibodies and neutralizes diverse SARS-CoV-2 variants. Chiyyeadu A, Asgedom G, Bruhn M, Rocha C, Schlegel TU, Neumann T, Galla M, Barbosa PV, Hoffmann M, Ehrhardt K, Ha TC, Morgan M, Schoeder CT, Pöhlmann S, Kalinke U, Schambach A. Clin Immunol. 2024 Jan 11:109902. doi: 10.1016/j.clim.2024.109902. Online ahead of print. PMID: 38218210
  21. Early-life vitamin A treatment rescues neonatal infection-induced durably impaired tolerogenic properties of celiac lymph nodes. Mangge Zou, Joern Pezoldt, Juliane Mohr, Lars Philipsen, Andrea Leufgen, Vuk Cerovic, Carolin Wiechers, Marina Pils, Diego Ortiz, Lianxu Hao, Juhao Yang, Michael Beckstette, Aline Dupont, Mathias Hornef, Petra Dersch, Till Strowig, Andreas J. Müller, Jens Raila, Jochen Huehn, Cell Reports. Volume 43, Issue 5, 2024, 114153, ISSN 2211-1247.
  22. Viral modulation of type II interferon increases T cell adhesion and virus spread. Jacobsen, C., Plückebaum, N., Ssebyatika, G. et al. Nat Commun. 15, 5318 (2024). https://doi.org/10.1038/s41467-024-49657-4
  23. A Novel Transmembrane CXCR4 Variant That Expands the WHIM Genotype-Phenotype Paradigm. Zmajkovicova, K., S. Pawar, S. O. Sharapova, C. B. Geier, I. Wiest, C. Nguyen, H. Monticelli, S. Maier-Munsa, K. Chen, J. W. Sleasman, S. Aleshkevich, E. Polyakova, I. Sakovich, K. Warnatz, B. Grimbacher, M. Proietti, N. Sondheimer, B. Ujhazi, S. Gordon, M. Ellison, M. Yilmaz, J. E. Walter, A. Badarau, A. G. Taveras, J. L. Neff, J. R. Bledsoe, and T. K. Tarrant. 2024. Blood Adv.
  24. Cross-regulation of Listeria monocytogenes and the host ubiquitin system in listeriosis. Zhuang, Y., J. B. Fischer, G. Nishanth, and D. Schlüter. 2024.  Eur J Cell Biol. 103: 151401.
  25. Genetic determinants of host- and virus-derived insertions for hepatitis E virus replication. Wißing, M. H., T. L. Meister, M. K. Nocke, A. Gömer, M. Masovic, L. Knegendorf, Y. Brüggemann, V. Bader, A. Siddharta, C. T. Bock, A. Ploss, S. P. Kenney, K. F. Winklhofer, P. Behrendt, H. Wedemeyer, E. Steinmann, and D. Todt. 2024. Nat Commun. 15: 4855.
  26. Treatment of moderate-to-severe atopic dermatitis with baricitinib: Results from an interim analysis of the TREATgermany registry. Traidl, S., L. Heinrich, D. Siegels, A. Heratizadeh, B. Kind, E. Haufe, S. Abraham, T. Schäfer, M. Augustin, I. Harder, A. Pinter, K. Schäkel, A. Wollenberg, K. Ertner, J. Ramaker-Brunke, A. Bong, S. Quist, H. Gorriahn-Maiterth, F. Schenck, M. Sticherling, I. Effendy, B. Schwarz, C. Handrick, A. Asmussen, S. Weidinger, J. Schmitt, and T. Werfel. 2024. J Eur Acad Dermatol Venereol.
  27. Inhibition of RNase 7 by RNase inhibitor promotes inflammation and Staphylococcus aureus growth: Implications for atopic dermatitis. Rademacher, F., A. Scheel, R. Gläser, L. Schröder, N. Heinemann, J. Bartels, S. Gerdes, D. Stölzl, E. Rodriguez, K. Döhner, S. Weidinger, T. Werfel, and J. Harder. 2024.  Allergy 79: 1573-1583.
  28. Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice. Ouwendijk, W. J. D., P. Roychoudhury, A. L. Cunningham, K. R. Jerome, D. M. Koelle, P. R. Kinchington, I. Mohr, A. C. Wilson, G. Verjans, and D. P. Depledge. 2024. J Virol. : e0185823.
  29. Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms. Osbelt, L., D. H. Almási É, M. Wende, S. Kienesberger, A. Voltz, T. R. Lesker, U. Muthukumarasamy, N. Knischewski, E. Nordmann, A. A. Bielecka, M. Giralt-Zúñiga, E. Kaganovitch, C. Kühne, C. Baier, M. Pietsch, M. Müsken, M. C. Greweling-Pils, R. Breinbauer, A. Flieger, D. Schlüter, R. Müller, M. Erhardt, E. L. Zechner, and T. Strowig. 2024. Nat Microbiol.
  30. Elevation of S2-bound α1-acid glycoprotein is associated with chronic hepatitis C virus infection and hepatocellular carcinoma. Oltmanns, C., B. Bremer, L. Kusche, P. Stål, R. Zenlander, J. Tauwaldt, I. Rydén, P. Påhlsson, M. Cornberg, and H. Wedemeyer. 2024. J Viral Hepat.
  31. CXCR6+CD69+ CD8+ T cells in the ascites are associated with disease severity in patients with liver cirrhosis. Niehaus, C., S. Klein, B. Strunz, E. Freyer, B. Maasoumy, H. Wedemeyer, N. K. Björkström, A. R. M. Kraft, and M. Cornberg. 2024.  JHEP Reports.  101074.
  32. FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice. Momenilandi, M., R. Lévy, S. Sobrino, J. Li, C. Lagresle-Peyrou, H. Esmaeilzadeh, A. Fayand, C. Le Floc’h, A. Guérin, E. D. Mina, D. Shearer, O. M. Delmonte, A. Yatim, K. Mulder, M. Mancini, D. Rinchai, A. Denis, A. L. Neehus, K. Balogh, S. Brendle, H. Rokni-Zadeh, M. Changi-Ashtiani, Y. Seeleuthner, C. Deswarte, B. Bessot, C. Cremades, M. Materna, A. Cederholm, M. Ogishi, Q. Philippot, O. Beganovic, M. Ackermann, M. Wuyts, T. Khan, S. Fouéré, F. Herms, J. Chanal, B. Palterer, J. Bruneau, T. J. Molina, S. Leclerc-Mercier, J. L. Prétet, L. Youssefian, H. Vahidnezhad, N. Parvaneh, K. G. Claeys, R. Schrijvers, M. Luka, P. Pérot, J. Fourgeaud, C. Nourrisson, P. Poirier, E. Jouanguy, S. Boisson-Dupuis, J. Bustamante, L. D. Notarangelo, N. Christensen, N. Landegren, L. Abel, N. Marr, E. Six, D. Langlais, T. Waterboer, F. Ginhoux, C. S. Ma, S. G. Tangye, I. Meyts, N. Lachmann, J. Hu, M. Shahrooei, X. Bossuyt, J. L. Casanova, and V. Béziat. 2024. Cell. 187: 2817-2837.e2831.
  33. High prevalence and clinical relevance of intrapulmonary vascular dilatations in patients undergoing TIPS implantation. Mauz, J. B., H. Schneider, D. Berliner, A. Tiede, L. Stockhoff, J. B. Hinrichs, H. Wedemeyer, B. C. Meyer, K. M. Olsson, B. Maasoumy, and T. L. Tergast. 2024. Clin Gastroenterol Hepatol.
  34. Deep mining of the Sequence Read Archive reveals major genetic innovations in coronaviruses and other nidoviruses of aquatic vertebrates. Lauber, C., X. Zhang, J. Vaas, F. Klingler, P. Mutz, A. Dubin, T. Pietschmann, O. Roth, B. W. Neuman, A. E. Gorbalenya, R. Bartenschlager, and S. Seitz. 2024. PLoS Pathog. 20: e1012163.
  35. Targeting cellular cathepsins inhibits hepatitis E virus entry. Klöhn, M., T. Burkard, J. Janzen, J. A. Haase, A. Gömer, R. Fu, G. Ssebyatika, M. K. Nocke, R. J. P. Brown, T. Krey, V. L. Dao Thi, V. Kinast, Y. Brüggemann, D. Todt, and E. Steinmann. 2024. Hepatology.
  36. B-cells absence in patients diagnosed as inborn errors of immunity: a registry-based study. Khoshnevisan, R., S. Hassanzadeh, C. Klein, M. Rohlfs, B. Grimbacher, N. Molavi, A. Zamanifar, A. Khoshnevisan, M. Jafari, B. Bagherpour, M. Behnam, S. Najafi, and R. Sherkat. 2024. Immunogenetics. 76: 189-202.
  37. Assessing computational predictions of antimicrobial resistance phenotypes from microbial genomes. Hu, K., F. Meyer, Z. L. Deng, E. Asgari, T. H. Kuo, P. C. Münch, and A. C. McHardy. 2024. Brief Bioinform. 25.
  38. Arsenic trioxide impacts hepatitis B virus core nuclear localization and efficiently interferes with HBV infection. Hofmann, S., J. Luther, V. Plank, A. Oswald, J. Mai, I. Simons, J. Miller, V. Falcone, L. Hansen-Palmus, H. Hengel, M. Nassal, U. Protzer, and S. Schreiner. 2024. Microbiol Spectr. 12: e0378823.
  39. DMSO and Its Role in Differentiation Impact Efficacy of Human Adenovirus (HAdV) Infection in HepaRG Cells. Hofmann, K., S. Hofmann, F. Weigl, J. Mai, and S. Schreiner. 2024. Viruses 16.
  40. Varicella zoster virus-induced autophagy in human neuronal and hematopoietic cells exerts antiviral activity. Heinz, J. L., D. M. Hinke, M. Maimaitili, J. Wang, I. K. D. Sabli, M. Thomsen, E. Farahani, F. Ren, L. Hu, T. Zillinger, A. Grahn, J. von Hofsten, G. Verjans, S. R. Paludan, A. Viejo-Borbolla, V. Sancho-Shimizu, and T. H. Mogensen. 2024. J Med Virol. 96: e29690.
  41. Next Generation Sequencing Outperforms Cultivation-Based Methods for Detection of Bacterial Genera in Bile After Liver Transplantation. Grobe, B., F. Wellhoner, F. Klein, P. Chhatwal, M. Vital, D. H. Pieper, T. Voigtlander, H. Lenzen, H. Wedemeyer, P. Solbach, and B. Heidrich. 2024.  J Clin Exp Hepatol. 14: 101265.
  42. The non-muscle actinopathy-associated mutation E334Q in cytoskeletal γ-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins. Greve, J. N., A. Marquardt, R. Heiringhoff, T. Reindl, C. Thiel, N. Di Donato, M. H. Taft, and D. J. Manstein. 2024. Elife. 12.
  43. The human adenovirus PI3K-Akt activator E4orf1 is targeted by the tumor suppressor p53. Göttig, L., S. Jummer, L. Staehler, P. Groitl, M. Karimi, P. Blanchette, K. Kosulin, P. E. Branton, and S. Schreiner. 2024.  J Virol. 98: e0170123.
  44. Birch pollen-induced signatures in dendritic cells are maintained upon additional cytomegalovirus exposure. Fneish, Z., J. Becker, F. Mulenge, F. Fneish, B. Costa, C. Traidl-Hoffmann, S. Gilles, and U. Kalinke. 2024. Gene 927: 148649.
  45. Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice. Fischer, A. A. M., H. B. Robertson, D. Kong, M. M. Grimm, J. Grether, J. Groth, C. Baltes, M. Fliegauf, F. Lautenschläger, B. Grimbacher, H. Ye, V. Helms, and W. Weber. 2024.  Small. : e2311834.
  46. Shared and Distinct Gut Microbiota in Spondyloarthritis, Acute Anterior Uveitis, and Crohn’s Disease. Essex, M., V. Rios Rodriguez, J. Rademacher, F. Proft, U. Lober, L. Marko, U. Pleyer, T. Strowig, J. Marchand, J. A. Kirwan, B. Siegmund, S. K. Forslund, and D. Poddubnyy. 2024. Arthritis Rheumatol. 76: 48-58.
  47. Phenotypic and pathomechanistic overlap between tapasin and TAP deficiencies. Elsayed, A., S. von Hardenberg, F. Atschekzei, T. Graalmann, C. Jänke, T. Witte, F. C. Ringshausen, and G. Sogkas. 2024.  J Allergy Clin Immunol.
  48. Tetramerization is essential for the enzymatic function of the Pseudomonas aeruginosa virulence factor UDP-glucose pyrophosphorylase. Dirr, L., S. Cleeves, I. Ramón Roth, L. Li, T. Fiebig, T. Ve, S. Häussler, A. Braun, M. von Itzstein, and J. I. Führing. 2024.  mBio. 15: e0211423.
  49. Management of chronic viral hepatitis B and D. Dietz-Fricke, C., and H. Wedemeyer. 2024. Clin Liver Dis (Hoboken) 23: e0221.
  50. Cell Culture Models for Hepatitis B and D Viruses Infection: Old Challenges, New Developments and Future Strategies. Carpentier, A. 2024. Viruses 16.
  51. An integrated molecular risk score early in life for subsequent childhood asthma risk. Böck, A., K. Urner, J. K. Eckert, M. Salvermoser, K. Laubhahn, S. Kunze, J. Kumbrink, M. P. Hoeppner, K. Kalkbrenner, S. Kreimeier, K. Beyer, E. Hamelmann, M. Kabesch, M. Depner, G. Hansen, J. Riedler, M. Roponen, E. Schmausser-Hechfellner, C. Barnig, A. Divaret-Chauveau, A. M. Karvonen, J. Pekkanen, R. Frei, C. Roduit, R. Lauener, and B. Schaub. 2024.  Clin Exp Allergy 54: 314-328.
  52. SHIFTR enables the unbiased identification of proteins bound to specific RNA regions in live cells. Aydin, J., A. Gabel, S. Zielinski, S. Ganskih, N. Schmidt, C. R. Hartigan, M. Schenone, S. A. Carr, and M. Munschauer. 2024. Nucleic Acids Res. 52: e26.
  53. The extracellular serine protease from Staphylococcus epidermidis elicits a type 2-biased immune response in atopic dermatitis patients. Abdurrahman, G., R. Pospich, L. Steil, M. Gesell Salazar, J. J. Izquierdo González, N. Normann, D. Mrochen, C. Scharf, U. Völker, T. Werfel, B. M. Bröker, L. M. Roesner, and L. Gómez-Gascón. 2024.  Front Immunol. 15: 1352704.
  54. Sensor macrophages derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs. Abdin, S. M., F. Mansel, A. R. Hashtchin, M. Ackermann, G. Hansen, B. Becker, B. Kick, N. Pham, H. Dietz, C. Schaniel, U. Martin, I. Spreitzer, and N. Lachmann. 2024.  Biofabrication 16.
  55. Nanopore guided annotation of transcriptome architectures J. S. Abebe, Y. Alwie, E. Fuhrmann, J. Leins, J. Mai, R. Verstraten, et al. bioRxiv
  56. A comprehensive genetic map of cytokine responses in Lyme borreliosis. Botey-Bataller, J., H. D. Vrijmoeth, J. Ursinus, B. J. Kullberg, C. C. van den Wijngaard, H. Ter Hofstede, A. Alaswad, M. K. Gupta, L. M. Roesner, J. Huehn, T. Werfel, T. F. Schulz, C. J. Xu, M. G. Netea, J. W. Hovius, L. A. B. Joosten, and Y. Li. 2024. Nat Commun. 15: 3795.
  57. Adaptation of Human iPSC-Derived Macrophages Toward an Alveolar Macrophage-Like Phenotype Post-Intra-Pulmonary Transfer into Murine Models. Hetzel, M., I. Gensch, M. Ackermann, and N. Lachmann. 2024.  Methods in Molecular Biology (Clifton, N.J.) 2713: 463-479.
  58. tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa. Krueger, J., M. Preusse, N. Oswaldo Gomez, Y. N. Frommeyer, S. Doberenz, A. Lorenz, A. Kordes, S. Grobe, M. Müsken, D. P. Depledge, S. L. Svensson, S. Weiss, V. Kaever, A. Pich, C. M. Sharma, Z. Ignatova, and S. Häussler. 2024.  Proc Natl Acad Sci U S A 121: e2312874121.
  59. γδ T cell profiling in a cohort of preterm infants reveals elevated frequencies of CD83+ γδ T cells in sepsis. León-Lara, X., A. S. Fichtner, M. Willers, T. Yang, K. Schaper, L. Riemann, J. Schöning, A. Harms, V. Almeida, A. Schimrock, A. Janssen, L. Ospina-Quintero, C. von Kaisenberg, R. Förster, M. Eberl, M. F. Richter, S. Pirr, D. Viemann, and S. Ravens. 2024. J Exp Med. 221.
  60. Ample evidence for the presence of HSV-1 LAT in non-neuronal ganglionic cells of mice and humans. Ouwendijk, W. J. D., P. Roychoudhury, A. L. Cunningham, K. R. Jerome, D. M. Koelle, P. R. Kinchington, I. Mohr, A. C. Wilson, G. Verjans, and D. P. Depledge. 2024. Reply to Wang et al., . J Virol. : e0052024.
  61. Current genetic diagnostics in inborn errors of immunity. Sake, S. M., X. Zhang, M. K. Rajak, M. Urbanek-Quaing, A. Carpentier, A. P. Gunesch, C. Grethe, A. Matthaei, J. Ruckert, M. Galloux, T. Larcher, R. Le Goffic, F. Hontonnou, A. K. Chatterjee, K., Hardenberg, S., I. Klefenz, D. Steinemann, N. Di Donato, U. Baumann, B. Auber, and C. Klemann. 2024.  Front Pediatr. 12: 1279112.
  62. OTULIN-related conditions: Report of a new case and review of the literature using GenIA. Caballero-Oteyza A, Crisponi L, Peng XP, Wang H, Mrovecova P, Olla S, Siguri C, Marnissi F, Jouhadi Z, Aksentijevich I, Grimbacher B, Proietti Clin Immunol. 2024 Jun 22;265:110292. Epub ahead of print.
  63. The RESIST Senior Individuals Cohort: Design, participant characteristics and aims. Roesner, L.M., Gupta, M.K., Kopfnagel, V. et al. GeroScience (2024).
  64. Standardized generation of human iPSC-derived hematopoietic organoids and macrophages utilizing a benchtop bioreactor platform under fully defined conditions M. Ackermann, F. Saleh, S. M. Abdin, A. Rafiei Hashtchin, I. Gensch, J. Golgath, et al. Stem Cell Res Ther.
  65. Novel hypermorphic variants in IRF2BP2 identified in patients with common variable immunodeficiency and autoimmunity M. Anim, G. Sogkas, N. Camacho-Ordonez, G. Schmidt, A. Elsayed, M. Proietti, et al. Clin Immunol.
  66. Hepatitis E virus: from innate sensing to adaptive immune responses Y. Brüggemann, M. Klöhn, H. Wedemeyer and E. Steinmann Nat Rev Gastroenterol Hepatol.
  67. Folic acid supplementation is associated with a decreased mortality and reduced hospital readmission in patients with decompensated alcohol-related liver cirrhosis L. Buttler, A. Tiede, M. Griemsmann, H. Rieland, J. Mauz, J. Kahlhöfer, et al. Clin Nutr.
  68. OTULIN-related conditions: Report of a new case and review of the literature using GenIA A. Caballero-Oteyza, L. Crisponi, X. P. Peng, H. Wang, P. Mrovecova, S. Olla, et al. Clin Immunol.
  69. Safety and efficacy of off-label bulevirtide monotherapy in patients with HDV with decompensated Child-B cirrhosis-A real-world case series C. Dietz-Fricke, E. Degasperi, M. Jachs, B. Maasoumy, F. P. Reiter, A. Geier, et al. Hepatology.
  70. Impending HCC diagnosis in patients with cirrhosis after HCV cure features a natural killer cell signature S. A. Engelskircher, P. C. Chen, B. Strunz, C. Oltmanns, T. Ristic, S. Owusu Sekyere, et al.Hepatology 2024 Vol. 80 Issue 1 Pages 202-222 Hepatology.
  71. Analysis of Replication, Cell Division-Mediated Spread, and HBV Envelope Protein-Dependent Pseudotyping of Three Mammalian Delta-like Agents G. E. Gnouamozi, Z. Zhang, V. Prasad, C. Lauber, S. Seitz and S. Urban Viruses.
  72. Real-time identification of epistatic interactions in SARS-CoV-2 from large genome collections G. Innocenti, M. Obara, B. Costa, H. Jacobsen, M. Katzmarzyk, L. Cicin-Sain, et al. Genome Biol.
  73. Viral modulation of type II interferon increases T cell adhesion and virus spread C. Jacobsen, N. Plückebaum, G. Ssebyatika, S. Beyer, L. Mendes-Monteiro, J. Wang, et al. Nat Commun.
  74. Sex-specific epigenetic signatures of circulating urate and its increase after BCG vaccination Z. Liu, T. O. Crișan, C. Qi, M. K. Gupta, X. Liu, S. Moorlag, et al. Res Sq.
  75. Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis F. Mulenge, O. L. Gern, L. M. Busker, A. Aringo, L. Ghita, I. Waltl, et al. J Neuroinflammation
  76. Orchestration of antiviral responses within the infected central nervous system A. Pavlou, F. Mulenge, O. L. Gern, L. M. Busker, E. Greimel, I. Waltl, et al. Cell Mol Immunol.
  77. Protection from environmental enteric dysfunction and growth improvement in malnourished newborns by amplification of secretory IgA L.  Perruzza, T. Rezzonico Jost, M. Raneri, G. Gargari, M. Palatella, B. De Ponte Conti, et al. Cell Rep Med.
  78. Molecular plasticity of herpesvirus nuclear egress analysed in situ V. Pražák, Y. Mironova, D. Vasishtan, C. Hagen, U. Laugks, Y. Jensen, et al. Nat Microbiol.
  79. Expansion of human γδ T cells in periphery: Lessons learned from development, infections, and compromised thymic function S. Ravens and E. Tolosa Eur J Immunol.
  80. The RESIST Senior Individuals Cohort: Design, participant characteristics and aims L. M. Roesner, M. K. Gupta, V. Kopfnagel, N. van Unen, Y. Kemmling, J. K. Heise, et al. Geroscience.
  81. Letter to the Editor: The WHO HDV RNA international standard does not reflect variability of real-world samples L. Sandmann, B. Bremer, K. Deterding, K. Port, B. Gey, C. Früchtel, et al. Hepatology
  82. Engineered HCMV-infected APCs enable the identification of new immunodominant HLA-restricted epitopes of anti-HCMV T-cell immunity M. M. Santamorena, S. Tischer-Zimmermann, A. Bonifacius, C. N. Mireisz, B. Costa, F. Khan, et al.HLA.
  83. Impact of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Children with Cystic Fibrosis and One or Two F508del Alleles M. Stahl, M. Dohna, S. Y. Graeber, O. Sommerburg, D. M. Renz, S. T. Pallenberg, et al. Eur Respir J.
  84. Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration Traidl-Hoffmann Allergy.
  85. Long-term outcome of hepatitis delta in different regions world-wide: Results of the Hepatitis Delta International Network A. Wranke, C. Lobato, E. Ceausu, G. N. Dalekos, M. Rizzetto, A. Turcanu, et al.Liver Int.
  86. Pathogen dynamics and discovery of novel viruses and enzymes by deep nucleic acid sequencing of wastewater E. Wyler, C. Lauber, A. Manukyan, A. Deter, C. Quedenau, L. G. Teixeira Alves, et al. Environ Int.
  87. ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA O. K. Greiner-Tollersrud, M. Krausz, V. Boehler, A. Polyzou, M. Seidl, A. Spahiu, et al. Cell Rep.
  88. Postnatal supplementation with alarmins S100a8/a9 ameliorates malnutrition-induced neonate enteropathy in mice
    Lisa Perruzza # 1 2, Julia Heckmann # 3, Tanja Rezzonico Jost 4, Matteo Raneri 4, Simone Guglielmetti 5 6, Giorgio Gargari , Martina Palatella , Maike Willers , Beate Fehlhaber , Christopher Werlein , Thomas Vogl , Johannes Roth , Fabio Grassi , Dorothee Viemann
    Nat Commun. 2024 Oct 4;15(1):8623. doi: 10.1038/s41467-024-52829-x.
  89. Early-life thymectomy leads to an increase of granzyme-producing γδ T cells in children with congenital heart disease
    Alexa Cramer , Tao Yang , Lennart Riemann , Vicente Almeida , Christoph Kammeyer , Yusuf E Abu , Elisa Gluschke , Svea Kleiner , Ximena León-Lara , Anika Janssen , Alejandro Hofmann , Alexander Horke , Constantin von Kaisenberg , Reinhold Förster , Philipp Beerbaum , Martin Boehne , Sarina Ravens Nat Commun. 2024 Nov 13;15(1):9841. doi: 10.1038/s41467-024-51673-3.
  90. A Hitchhiker’s Guide Through the Cell: The World According to the Capsids of Alphaherpesviruses. Döhner K, Serrero MC, Viejo-Borbolla A, Sodeik B. Annu Rev Virol. 2024 Sep;11(1):215-238. Epub 2024 Aug 30.
  91. MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids. Moschonas GD, Delhaye L, Cooreman R, Hüsers F, Bhat A, Stylianidou Z, De Bousser E, De Pryck L, Grzesik H, De Sutter D, Parthoens E, De Smet AS, Maciejczuk A, Lippens S, Callewaert N, Vandekerckhove L, Debyser Z, Sodeik B, Eyckerman S, Saelens X. Cell Host Microbe. 2024 Oct 9;32(10):1705-1724.e14.
  92. Enhancing HBV-specific T cell responses through a combination of epigenetic modulation and immune checkpoint inhibition. Urbanek-Quaing M, Chou YH, Gupta MK, Steppich K, Bremer B, Schmaus H, Deterding K, Maasoumy B, Wedemeyer H, Xu CJ, Kraft ARM, Cornberg M. Hepatology. 2024 Dec 19. Epub ahead of print.
  93. Inborn Errors of Immunity (IEI) breaking immune homeostasis and tolerance: a key role for T regulatory cells
    V. De Rosa, G. Sogkas and R. Bacchetta Front Immunol 2024 Vol. 15 Pages 1532079
    Accession Number: 39749344 PMCID: PMC11693703 DOI: 10.3389/fimmu.2024.1532079
  94. Type-Specific Impacts of Protein Defects in Pathogenic NFKB2 Variants: Novel Clinical Findings From 138 Patients
    J. Meissner, M. Fliegauf, B. Grimbacher and C. Klemann J Allergy Clin Immunol Pract 2024 Accession Number: 39447838 DOI: 10.1016/j.jaip.2024.10.015
  95. PGM3 insufficiency: a glycosylation disorder causing a notable T cell defect L. Yang, B. Zerbato, A. Pessina, L. Brambilla, V. Andreani, S. Frey-Jakobs, et al. Front Immunol 2024 Vol. 15 Pages 1500381 Accession Number: 39776909 PMCID: PMC11703855 DOI: 10.3389/fimmu.2024.1500381
  96. The antimicrobial protein RNase 7 directly restricts herpes simplex virus infection of human keratinocytes J. Zeitvogel, K. Döhner, I. Klug, F. Rademacher, R. Gläser, B. Sodeik, et al. J Med Virol 2024 Vol. 96 Issue 10 Pages e29942 Accession Number: 39360648 DOI: 10.1002/jmv.29942
  97. MAVS signaling shapes microglia responses to neurotropic virus infection O. L. Gern, A. Pavlou, F. Mulenge, L. M. Busker, L. Ghita, A. Aringo, et al. J Neuroinflammation 2024 Vol. 21 Issue 1 Pages 264 Accession Number: 39425188 PMCID: PMC11490141 DOI: 10.1186/s12974-024-03258-6
  98. Biochemical characterization of cardiac α-actin mutations A21V and D26N implicated in hypertrophic cardiomyopathy J. N. Greve, F. V. Schwäbe, M. H. Taft and D. J. Manstein Cytoskeleton (Hoboken) 2024 Vol. 81 Issue 12 Pages 815-831 Accession Number: 38459932 PMCID: PMC11615838 DOI: 10.1002/cm.21852
  99. Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins A. S. Hartke, C. S. Schreiber, K. Lau, I. Wiesweg, I. Waltl, U. Kalinke, et al. Neurobiol Dis 2024 Vol. 205 Pages 106773 Accession Number: 39710067 DOI: 10.1016/j.nbd.2024.106773
  100. Reply to Wang et al., „Ample evidence for the presence of HSV-1 LAT in non-neuronal ganglionic cells of mice and humans“ W. J. D. Ouwendijk, P. Roychoudhury, A. L. Cunningham, K. R. Jerome, D. M. Koelle, P. R. Kinchington, et al. J Virol 2024 Pages e0052024 Accession Number: 38700354 DOI: 10.1128/jvi.00520-24
  101. Physiologists as medical scientists: An early warning from the German academic system  K. Streckfuss-Bomeke, N. Krankel, C. Maack, R. B. Schnabel, L. C. Zelarayan, N. Frey, et al. Physiol Rep 2024 Vol. 12 Issue 21 Pages e70055 Accession Number: 39462686 PMCID: PMC11513198 DOI: 10.14814/phy2.70055
  102. Insertion of a transjugular intrahepatic portosystemic shunt leads to sustained reversal of systemic inflammation in patients with decompensated liver cirrhosis A. Tiede, L. Stockhoff, Z. Liu, H. Rieland, J. B. Mauz, V. Ohlendorf, et al. Clin Mol Hepatol 2024 Accession Number: 39568127 DOI: 10.3350/cmh.2024.0587
  103. DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells Z. Yu, V. Sasidharan-Nair, T. Buchta, A. Bonifacius, F. Khan, B. Pietzsch, et al. PLoS Pathog 2024 Vol. 20 Issue 9 Pages e1012581 Accession Number: 39325839 PMCID: PMC11460711 DOI: 10.1371/journal.ppat.1012581
  104. Structural characterization of the full-length Hantaan virus polymerase J. R. Keown, L. Carrique, B. E. Nilsson-Payant, E. Fodor and J. M. Grimes PLoS Pathog 2024 Vol. 20 Issue 12 Pages e1012781 Accession Number: 39652621 PMCID: PMC11658695 DOI: 10.1371/journal.ppat.1012781
  105. A proteome-wide structural systems approach reveals insights into protein families of all human herpesviruses T. K. Soh, S. Ognibene, S. Sanders, R. Schäper, B. B. Kaufer and J. B. Bosse Nat Commun 2024 Vol. 15 Issue 1 Pages 10230 Accession Number: 39592652 PMCID: PMC11599850 DOI: 10.1038/s41467-024-54668-2
  106. Attenuated effector T cells are linked to control of chronic HBV infection K. Heim, Sagar, O. Sogukpinar, S. Llewellyn-Lacey, D. A. Price, F. Emmerich, et al. Nat Immunol 2024 Vol. 25 Issue 9 Pages 1650-1662 Accession Number: 39198634 PMCID: PMC11362014 DOI: 10.1038/s41590-024-01928-4
  107. Limited stability of Hepatitis B virus RNA in plasma and serum V. Ohlendorf, B. Bremer, L. Sandmann, C. Mix, T. Tergast, M. Cornberg, et al. Sci Rep 2024 Vol. 14 Issue 1 Pages 27128 Accession Number: 39511219 PMCID: PMC11543676 DOI: 10.1038/s41598-024-77329-2
  108. Limited Value of HBV-RNA for Relapse Prediction After Nucleos(t)ide Analogue Withdrawal in HBeAg-negative Hepatitis B Patients V. Ohlendorf, M. Wubbolding, C. Honer Zu Siederdissen, B. Bremer, K. Deterding, H. Wedemeyer, et al. J Viral Hepat 2024 Accession Number: 39425534 DOI: 10.1111/jvh.14026
  109. Enhancing HBV-specific T cell responses through a combination of epigenetic modulation and immune checkpoint inhibition M. Urbanek-Quaing, Y. H. Chou, M. K. Gupta, K. Steppich, B. Bremer, H. Schmaus, et al. Hepatology 2024 Accession Number: 39700467 DOI: 10.1097/HEP.0000000000001202
  110. Epitope-focused immunogens targeting the hepatitis C virus glycoproteins induce broadly neutralizing antibodies K. Nagarathinam, A. Scheck, M. Labuhn, L. J. Ströh, E. Herold, B. Veselkova, et al. Sci Adv 2024 Vol. 10 Issue 49 Pages eado2600 Accession Number: 39642219 PMCID: PMC11623273 DOI: 10.1126/sciadv.ado2600
  111. Tuberculosis in otherwise healthy adults with inherited TNF deficiency A. A. Arias, A. L. Neehus, M. Ogishi, V. Meynier, A. Krebs, T. Lazarov, et al. Nature 2024 Vol. 633 Issue 8029 Pages 417-425 Accession Number: 39198650 PMCID: PMC11390478 DOI: 10.1038/s41586-024-07866-3
  112. Ultrasound-triggered drug release in vivo from antibubble-loaded macrophages O. Desai, M. Köster, D. Kloos, N. Lachmann, H. Hauser, A. Poortinga, et al. J Control Release 2024 Accession Number: 39653149 DOI: 10.1016/j.jconrel.2024.12.007
  113. Human CFTR deficient iPSC-macrophages reveal impaired functional and transcriptomic response upon Pseudomonas aeruginosa infection C. Rodriguez Gonzalez, D. Basílio-Queirós, A. L. Neehus, S. Merkert, D. Tschritter, S. Ünal, et al. Front Immunol 2024 Vol. 15 Pages 1397886 Accession Number: 39606224 PMCID: PMC11601075 DOI: 10.3389/fimmu.2024.1397886
  114. Deciphering the molecular complexity of the IKZF1plus genomic profile using Optical Genome Mapping
    Jonathan L Lühmann , Martin Zimmermann , Winfried Hofmann , Anke K Bergmann , Anja Möricke , Gunnar Cario , Martin Schrappe , Brigitte Schlegelberger , Martin Stanulla , Doris Steinemann
    Haematologica. 2024 May 1;109(5):1582-1587. doi: 10.3324/haematol.2023.284115.
  115. Macrocytic anemia and polychondritis: VEXAS syndrome M. Zeisbrich, V. Schindler, M. Krausz, M. Proietti, P. Mrovecova, R. E. Voll, et al. Z Rheumatol 2024 Vol. 83 Issue 3 Pages 229-233 Accession Number: 36735069 PMCID: PMC10973061 DOI: 10.1007/s00393-023-01318-5
  116. Reanalysis of single-cell RNA sequencing data does not support herpes simplex virus 1 latency in non-neuronal ganglionic cells in mice W. J. D. Ouwendijk, P. Roychoudhury, A. L. Cunningham, K. R. Jerome, D. M. Koelle, P. R. Kinchington, et al. J Virol 2024 Pages e0185823 Accession Number: 38445887 DOI: 10.1128/jvi.01858-23
    1. Identification of Compounds Preventing A. fumigatus Biofilm Formation by Inhibition of the Galactosaminogalactan Deacetylase Agd3 Seegers CII, Lee DJ, Zarnovican P, Kirsch SH, Müller R, Haselhorst T, Routier FH. Int J Mol Sci. 2023 Jan 17;24(3):1851. doi: 10.3390/ijms24031851. PMID: 36768176; PMCID: PMC9915216.
    2. Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria. Rosain J, Neehus AL, Manry J, Yang R, Le Pen J, Daher W, Liu Z, Chan YH, Tahuil N, Türel Ö, Bourgey M, Ogishi M, Doisne JM, Izquierdo HM, Shirasaki T, Le Voyer T, Guérin A, Bastard P, Moncada-Vélez M, Han JE, Khan T, Rapaport F, Hong SH, Cheung A, Haake K, Mindt BC, Pérez L, Philippot Q, Lee D, Zhang P, Rinchai D, Al Ali F, Ahmad Ata MM, Rahman M, Peel JN, Heissel S, Molina H, Kendir-Demirkol Y, Bailey R, Zhao S, Bohlen J, Mancini M, Seeleuthner Y, Roelens M, Lorenzo L, Soudée C, Paz MEJ, González ML, Jeljeli M, Soulier J, Romana S, L’Honneur AS, Materna M, Martínez-Barricarte R, Pochon M, Oleaga-Quintas C, Michev A, Migaud M, Lévy R, Alyanakian MA, Rozenberg F, Croft CA, Vogt G, Emile JF, Kremer L, Ma CS, Fritz JH, Lemon SM, Spaan AN, Manel N, Abel L, MacDonald MR, Boisson-Dupuis S, Marr N, Tangye SG, Di Santo JP, Zhang Q, Zhang SY, Rice CM, Béziat V, Lachmann N, Langlais D, Casanova JL, Gros P, Bustamante J. Cell. 2023 Feb 2;186(3):621-645.e33. doi: 10.1016/j.cell.2022.12.038. PMID: 36736301; PMCID: PMC9907019.
    3. Silent neonatal influenza A virus infection primes systemic antimicrobial immunity. Heinemann AS, Stalp JL, Bonifacio JPP, Silva F, Willers M, Heckmann J, Fehlhaber B, Völlger L, Raafat D, Normann N, Klos A, Hansen G, Schmolke M, Viemann D. Front Immunol. 2023 Jan 24;14:1072142. doi: 10.3389/fimmu.2023.1072142. PMID: 36761727; PMCID: PMC9902881.
    4. Transcriptome Dynamics of Pseudomonas aeruginosa during Transition from Overlapping To Non-Overlapping Cell Cycles. Alpers K, Vatareck E, Gröbe L, Müsken M, Scharfe M, Häussler S, Tomasch J. mSystems. 2023 Apr 27;8(2):e0113022. doi: 10.1128/msystems.01130-22. Epub 2023 Feb 14. PMID: 36786632; PMCID: PMC10134858.
    5. Viral dew: Phase separation and the formation of viral replication compartments. Bosse JB, Brune W. PLoS Pathog. 2023 Feb 16;19(2):e1011145. doi: 10.1371/journal.ppat.1011145. PMID: 36795674; PMCID: PMC9934448.
    6. Sequencing the B Cell Receptor Repertoires of Antibody-Deficient Individuals With and Without Infection Susceptibility. Lim YW, Ramirez NJ, Asensio MA, Chiang Y, Müller G, Mrovecova P, Mitsuiki N, Krausz M, Camacho-Ordonez N, Warnatz K, Adler AS, Grimbacher B. J Clin Immunol. 2023 Jul;43(5):940-950. doi: 10.1007/s10875-023-01448-0. Epub 2023 Feb 24. PMID: 36826743; PMCID: PMC10276080.
    7. Brief report: Assessment of mucosal barrier integrity using serological biomarkers in preclinical stages of rheumatoid arthritis. Gilbert BTP, Lamacchia C, Amend L, Strowig T, Rodriguez E, Palmer G, Finckh A. Front Immunol. 2023 Feb 16;14:1117742. doi: 10.3389/fimmu.2023.1117742. PMID: 36875067; PMCID: PMC9977794.
    8. Pathogen spectra in hospitalised and nonhospitalised children with community-acquired pneumonia. Wetzke M, Schütz K, Kopp MV, Seidenberg J, Vogelberg C, Ankermann T, Happle C, Voigt G, Köster H, Illig T, Lex C, Schuster A, Maier R, Panning M, Barten G, Rohde G, Welte T, Hansen G. ERJ Open Res. 2023 Mar 13;9(2):00286-2022. doi: 10.1183/23120541.00286-2022. PMID: 36923566; PMCID: PMC10009707.
    9. Imaging cytomegalovirus infection and ensuing immune responses. Bošnjak B, Lueder Y, Messerle M, Förster R. Curr Opin Immunol. 2023 Jun;82:102307. doi: 10.1016/j.coi.2023.102307. Epub 2023 Mar 28. PMID: 36996701.
    10. Structural insights into hepatitis C virus neutralization. Ströh LJ, Krey T. Curr Opin Virol. 2023 Jun;60:101316. doi: 10.1016/j.coviro.2023.101316. Epub 2023 Mar 29. PMID: 37001334.
    11. ChemGAPP: a tool for chemical genomics analysis and phenotypic profiling. Doherty HM, Kritikos G, Galardini M, Banzhaf M, Moradigaravand D. Bioinformatics. 2023 Apr 3;39(4):btad171. doi: 10.1093/bioinformatics/btad171. PMID: 37014365; PMCID: PMC10085634.oherty HM, Kritikos G, Galardini M, Banzhaf M, Moradigaravand D.  Bioinformatics. 2023 Apr 3;39(4):btad171.
    12. Immunological scars after cure of hepatitis C virus infection: Long-HepC?  Cornberg M, Mischke J, Kraft AR, Wedemeyer H. Curr Opin Immunol. 2023 Jun;82:102324. doi: 10.1016/j.coi.2023.102324. Epub 2023 Apr 10. PMID: 37043890.
    13. The link between rheumatic disorders and inborn errors of immunity. Sogkas G, Witte T. EBioMedicine. 2023 Apr;90:104501. doi: 10.1016/j.ebiom.2023.104501. Epub 2023 Mar 2. PMID: 36870198; PMCID: PMC9996386.
    14. The GAIN Registry – a New Prospective Study for Patients with Multi-organ Autoimmunity and Autoinflammation. Staus P, Rusch S, El-Helou S, Müller G, Krausz M, Geisen U, Caballero-Oteyza A, Krüger R, Bakhtiar S, Lee-Kirsch MA, Fasshauer M, Baumann U, Hoyer BF, Farela Neves J, Borte M, Carrabba M, Hauck F, Ehl S, Bader P, von Bernuth H, Atschekzei F, Seppänen MRJ, Warnatz K, Nieters A, Kindle G, Grimbacher B. J Clin Immunol. 2023 Aug;43(6):1289-1301. doi: 10.1007/s10875-023-01472-0. Epub 2023 Apr 21. PMID: 37084016; PMCID: PMC10119522.
    15. Crystal structure of the N-terminal domain of the effector protein SidI of Legionella pneumophila reveals a glucosyl transferase domain. Machtens DA, Willerding JM, Eschenburg S, Reubold TF. Biochem Biophys Res Commun. 2023 Jun 18;661:50-55. doi: 10.1016/j.bbrc.2023.04.029. Epub 2023 Apr 14. PMID: 37087798.
    16. The natural product chlorotonil A preserves colonization resistance and prevents relapsing Clostridioides difficile infection. Bublitz A, Brauer M, Wagner S, Hofer W, Müsken M, Deschner F, Lesker TR, Neumann-Schaal M, Paul LS, Nübel U, Bartel J, Kany AM, Zühlke D, Bernecker S, Jansen R, Sievers S, Riedel K, Herrmann J, Müller R, Fuchs TM, Strowig T. Cell Host Microbe.
      2023 May 10;31(5):734-750.e8. doi: 10.1016/j.chom.2023.04.003. Epub 2023 Apr 24.
    17. Apobec3A Deamination Functions Are Involved in Antagonizing Efficient Human Adenovirus Replication and Gene Expression. Göttig L, Weiß C, Stubbe M, Hanrieder L, Hofmann S, Grodziecki A, Stadler D, Carpentier A, Protzer U, Schreiner S. mBio. 2023 Jun 27;14(3):e0347822. doi: 10.1128/mbio.03478-22. Epub 2023 May 8. PMID: 37154747; PMCID: PMC10294656.
    18. SUMO Modification of Hepatitis B Virus Core Mediates Nuclear Entry, Promyelocytic Leukemia Nuclear Body Association, and Efficient Formation of Covalently Closed Circular DNA. Hofmann S, Plank V, Groitl P, Skvorc N, Hofmann K, Luther J, Ko C, Zimmerman P, Bruss V, Stadler D, Carpentier A, Rezk S, Nassal M, Protzer U, Schreiner S. Microbiol Spectr. 2023 Jun 15;11(3):e0044623. doi: 10.1128/spectrum.00446-23. Epub 2023 May 18. PMID: 37199632; PMCID: PMC10269885.
    19. Hand eczema leaves systemic traces. Roesner LM, Wittmann M. Br J Dermatol. 2023 Aug 24;189(3):e56-e59. doi: 10.1093/bjd/ljad178. PMID: 37226228.
    20. Helicobacter spp. are prevalent in wild mice and protect from lethal Citrobacter rodentium infection in the absence of adaptive immunity. Zhao B, Osbelt L, Lesker TR, Wende M, Galvez EJC, Hönicke L, Bublitz A, Greweling-Pils MC, Grassl GA, Neumann-Schaal M, Strowig T. Cell Rep. 2023 Jun 27;42(6):112549. doi: 10.1016/j.celrep.2023.112549. Epub 2023 May 26. PMID: 37245209.
    21. Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells. Jirmo AC, Grychtol R, Gaedcke S, Liu B, DeStefano S, Happle C, Halle O, Monteiro JT, Habener A, Breiholz OD, DeLuca D, Hansen G. Front Immunol. 2023 May 12;14:1127485. doi: 10.3389/fimmu.2023.1127485. PMID: 37251386; PMCID: PMC10213693.
    22. Colonization of peripheral ganglia by herpes simplex virus type 1 and 2; Kai A Kropp, Guorong Sun, Abel Viejo-Borbolla, Current Opinion in Virology, Volume 60, June 2023, 101333, ISSN 1879-6257, https://doi.org/10.1016/j.coviro.2023.101333.
    23. Pulsed antibiotic treatments of gnotobiotic mice manifest in complex bacterial community dynamics and resistance effects. Münch PC, Eberl C, Woelfel S, Ring D, Fritz A, Herp S, Lade I, Geffers R, Franzosa EA, Huttenhower C, McHardy AC, Stecher B. Cell Host Microbe. 2023 Jun 14;31(6):1007-1020.e4. doi: 10.1016/j.chom.2023.05.013. Epub 2023 Jun 5. PMID: 37279755.
    24. MCK2-mediated MCMV infection of macrophages and virus dissemination to the salivary gland depends on MHC class I molecules. Bošnjak B, Henze E, Lueder Y, Do KTH, Rezalotfi A, Čuvalo B, Ritter C, Schimrock A, Willenzon S, Georgiev H, Fritz L, Galla M, Wagner K, Messerle M, Förster R. Cell Rep. 2023 Jun 27;42(6):112597. doi: 10.1016/j.celrep.2023.112597. Epub 2023 Jun 7. PMID: 37289588.
    25. C4b-binding protein inhibits particulate- and crystalline-induced NLRP3 inflammasome activation. Bierschenk D, Papac-Milicevic N, Bresch IP, Kovacic V, Bettoni S, Dziedzic M, Wetsel RA, Eschenburg S, Binder CJ, Blom AM, King BC. Front Immunol. 2023 May 22:14:1149822. doi: 10.3389/fimmu.2023.1149822. eCollection 2023.
    26. Validation of the Asthma Severity Scoring System (ASSESS) in the ALLIANCE Cohort. Grychtol R, Riemann L, Gaedcke S, Liu B, DeLuca D, Förster R, Maison N, Thiele D, Jakobs N, Bahmer T, Meyer M, Foth S, Weber S, Rietschel E, Rabe KF, Kopp MV, von Mutius E, Dittrich AM, Hansen G; ALLIANCE Study Group as part of the German Center for Lung Research (DZL). J Allergy Clin Immunol. 2023 Jun;151(6):1525-1535.e4. doi: 10.1016/j.jaci.2023.01.027. Epub 2023 Feb 15. PMID: 36804993.
    27. SPI-1 virulence gene expression modulates motility of Salmonella Typhimurium in a proton motive force- and adhesins-dependent manner. Saleh DO, Horstmann JA, Giralt-Zúñiga M, Weber W, Kaganovitch E, Durairaj AC, Klotzsch E, Strowig T, Erhardt M. PLoS Pathog. 2023 Jun 14;19(6):e1011451. doi: 10.1371/journal.ppat.1011451. PMID: 37315106; PMCID: PMC10298799.
    28. Epistatic interactions between the high pathogenicity island and other iron uptake systems shape Escherichia coli extra-intestinal virulence. Royer G, Clermont O, Marin J, Condamine B, Dion S, Blanquart F, Galardini M, Denamur E. Nat Commun. 2023 Jun 20;14(1):3667. doi: 10.1038/s41467-023-39428-y. PMID: 37339949; PMCID: PMC10282060.
    29. Mouse Liver-Expressed Shiftless Is an Evolutionarily Conserved Antiviral Effector Restricting Human and Murine Hepaciviruses. Zhang Y, Kinast V, Sheldon J, Frericks N, Todt D, Zimmer M, Caliskan N, Brown RJP, Steinmann E, Pietschmann T. Microbiol Spectr. 2023 Aug 17;11(4):e0128423. doi: 10.1128/spectrum.01284-23. Epub 2023 Jun 21. PMID: 37341610; PMCID: PMC10433982.
    30. Hepatitis D virus infection, innate immune response and antiviral treatments in stem cell-derived hepatocytes. Lange F, Garn J, Anagho HA, Vondran FWR, von Hahn T, Pietschmann T, Carpentier A. Liver Int. 2023 Oct;43(10):2116-2129. doi: 10.1111/liv.15655. Epub 2023 Jun 27. PMID: 37366005.
    31. Differentiation of IL-26+ TH17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis. Fries A, Saidoune F, Kuonen F, Dupanloup I, Fournier N, Guerra de Souza AC, Haniffa M, Ma F, Gudjonsson JE, Roesner L, Li Y, Werfel T, Conrad C, Gottardo R, Modlin RL, Di Domizio J, Gilliet M. Nat Commun. 2023 Jun 30;14(1):3878. doi: 10.1038/s41467-023-39484-4. PMID: 37391412; PMCID: PMC10313793.
    32. Activated Phosphoinositide 3-Kinase δ Syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity. Maccari ME, Wolkewitz M, Schwab C, Lorenzini T, Leiding JW, Aladjdi N, Abolhassani H, Abou-Chahla W, Aiuti A, Azarnoush S, Baris S, Barlogis V, Barzaghi F, Baumann U, Bloomfield M, Bohynikova N, Bodet D, Boutboul D, Bucciol G, Buckland MS, Burns SO, Cancrini C, Cathébras P, Cavazzana M, Cheminant M, Chinello M, Ciznar P, Coulter TI, D’Aveni M, Ekwall O, Eric Z, Eren E, Fasth A, Frange P, Fournier B, Garcia-Prat M, Gardembas M, Geier C, Ghosh S, Goda V, Hammarström L, Hauck F, Heeg M, Heropolitanska-Pliszka E, Hilfanova A, Jolles S, Karakoc-Aydiner E, Kindle GR, Kiykim A, Klemann C, Koletsi P, Koltan S, Kondratenko I, Körholz J, Krüger R, Jeziorski E, Levy R, Le Guenno G, Lefevre G, Lougaris V, Marzollo A, Mahlaoui N, Malphettes M, Meinhardt A, Merlin E, Meyts I, Milota T, Moreira F, Moshous D, Mukhina A, Neth O, Neubert J, Neven B, Nieters A, Nove-Josserand R, Oksenhendler E, Ozen A, Olbrich P, Perlat A, Pac M, Schmid JP, Pacillo L, Parra-Martinez A, Paschenko O, Pellier I, Sefer AP, Plebani A, Plantaz D, Prader S, Raffray L, Ritterbusch H, Riviere JG, Rivalta B, Rusch S, Sakovich I, Savic S, Scheible R, Schleinitz N, Schuetz C, Schulz A, Sediva A, Semeraro M, Sharapova SO, Shcherbina A, Slatter MA, Sogkas G, Soler-Palacin P, Speckmann C, Stephan JL, Suarez F, Tommasini A, Trück J, Uhlmann A, van Aerde KJ, van Montfrans J, von Bernuth H, Warnatz K, Williams T, Worth AJJ, Ip W, Picard C, Catherinot E, Nademi Z, Grimbacher B, Forbes Satter LR, Kracker S, Chandra A, Condliffe AM, Ehl S; European Society for Immunodeficiencies Registry Working Party. J Allergy Clin Immunol. 2023 Oct;152(4):984-996.e10. doi: 10.1016/j.jaci.2023.06.015. Epub 2023 Jun 28. PMID: 37390899.
    33. Dynamics of reactive astrocytes fosters tissue regeneration after cuprizone-induced demyelination. Schröder LJ, Mulenge F, Pavlou A, Skripuletz T, Stangel M, Gudi V, Kalinke U. Glia. 2023 Nov;71(11):2573-2590. doi: 10.1002/glia.24440. Epub 2023 Jul 17. PMID: 37455566.
    34. S100A9 is indispensable for survival of pneumococcal pneumonia in mice. Ostermann L, Seeliger B, David S, Flasche C, Maus R, Reinboth MS, Christmann M, Neumann K, Brand K, Seltmann S, Bühling F, Paton JC, Roth J, Vogl T, Viemann D, Welte T, Maus UA.  PLoS Pathog. 2023 Jul 19;19(7):e1011493. doi: 10.1371/journal.ppat.1011493. PMID: 37467233; PMCID: PMC10355425.
    35. Longitudinal development of the airway metagenome of preterm very low birth weight infants during the first two years of life.  Rosenboom I, Pust MM, Pirr S, Bakker A, Willers M, Davenport CF, Wiehlmann L, Viemann D, Tümmler B. ISME Commun. 2023 Jul 20;3(1):75. doi: 10.1038/s43705-023-00285-x. PMID: 37474785; PMCID: PMC10359316.
    36. Fecal Immunoglobulin Levels as a Modifier of the Gut Microbiome in Patients with Common Variable Immunodeficiency.  NNöltner C, Bulashevska A, Hübscher K, Haberstroh H, Grimbacher B, Proietti M. J Clin Immunol. 2023 Aug;43(6):1208-1220. doi: 10.1007/s10875-023-01469-9. Epub 2023 Mar 24. PMID: 36961604; PMCID: PMC10354144.
    37. HSV-1 exploits host heterochromatin for nuclear egress. Lewis HC, Kelnhofer-Millevolte LE, Brinkley MR, Arbach HE, Arnold EA, Sanders S, Bosse JB, Ramachandran S, Avgousti DC. J Cell Biol. 2023 Sep 4;222(9):e202304106. doi: 10.1083/jcb.202304106. Epub 2023 Jul 26. PMID: 37516914; PMCID: PMC10373338.
    38. Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct-acting antivirals. Bi W, Kraft A, Engelskircher S, Mischke J, Witte M, Klawonn F, van Ham M, Cornberg M, Wedemeyer H, Hengst J, Jänsch L. Eur J Immunol. 2023 Nov;53(11):e2250291. doi: 10.1002/eji.202250291. Epub 2023 Aug 6. PMID: 37515498.
    39. Spatially resolved protein map of intact human cytomegalovirus virions. Bogdanow B, Gruska I, Mühlberg L, Protze J, Hohensee S, Vetter B, Bosse JB, Lehmann M, Sadeghi M, Wiebusch L, Liu F. Nat Microbiol. 2023 Sep;8(9):1732-1747. doi: 10.1038/s41564-023-01433-8. Epub 2023 Aug 7. PMID: 37550507; PMCID: PMC10465357.
    40. Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection. Sci Immunol. Forde AJ, Kolter J, Zwicky P, Baasch S, Lohrmann F, Eckert M, Gres V, Lagies S, Gorka O, Rambold AS, Buescher JM, Kammerer B, Lachmann N, Prinz M, Groß O, Pearce EJ, Becher B, Henneke P. Sci Immunol. 2023 Aug 18;8(86):eadg3517. doi: 10.1126/sciimmunol.adg3517. Epub 2023 Aug 11. PMID: 37566679.orde AJ, Kolter J, Zwicky P, Baasch S, Lohrmann F, Eckert M, Gres V, Lagies S, Gorka O, Rambold AS, Buescher JM, Kammerer B, Lachmann N, Prinz M, Groß O, Pearce EJ, Becher B, Henneke P.  2023 Aug 18;8(86):eadg3517.
    41. Cultivation-based characterization of biliary microbiota in bile samples collected during routine endoscopic retrograde cholangiography: 10 years of experience at a tertiary center. Forster K, Klein F, Simon N, Chhatwal P, Ziesing S, Heidrich B, Solbach P. Eur J Gastroenterol Hepatol. 2023 Oct 1;35(10):1159-1167. doi: 10.1097/MEG.0000000000002633. Epub 2023 Aug 11. PMID: 37577778.
    42. Establishment of an In Bacterio Assay for the Assessment of Carbon Storage Regulator A (CsrA) Inhibitors. Wu Y, Zoller BGE, Kamal MAM, Hotop SK, Lehr CM, Brönstrup M, Dersch P, Empting M. Chembiochem. 2023 Aug 15;24(16):e202300369. doi: 10.1002/cbic.202300369. Epub 2023 Jul 25. PMID: 37435861.
    43. OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6. Zhao Y, Ruan J, Li Z, Su X, Chen K, Lin Y, Cai Y, Wang P, Liu B, Schlüter D, Liang G, Wang X. Clin Transl Med. 2023 Aug;13(8):e1385. doi: 10.1002/ctm2.1385. PMID: 37608493; PMCID: PMC10444971.
    44. Virucidal activity of oral, hand, and surface disinfectants against respiratory syncytial virus. Meister TL, Friesland M, Frericks N, Wetzke M, Haid S, Steinmann J, Todt D, Pietschmann T, Steinmann E. J Hosp Infect. 2023 Nov;141:25-32. doi: 10.1016/j.jhin.2023.08.009. Epub 2023 Aug 23. PMID: 37625461.
    45. A TriPPPro-Nucleotide Reporter with Optimized Cell-Permeable Dyes for Metabolic Labeling of Cellular and Viral DNA in Living Cells.  Sterrenberg VT, Stalling D, Knaack JIH, Soh TK, Bosse JB, Meier C. Angew Chem Int Ed Engl. 2023 Sep 18;62(38):e202308271. doi: 10.1002/anie.202308271. Epub 2023 Aug 9. PMID: 37435767.
    46. Dupilumab strengthens herpes simplex virus type 1-specific immune responses in atopic dermatitis. Traidl S, Harries L, Kienlin P, Begemann G, Roesner LM, Werfel T. J Allergy Clin Immunol. 2023 Dec;152(6):1460-1469.e5. doi: 10.1016/j.jaci.2023.08.024. Epub 2023 Sep 1. PMID: 37660986.
    47. Secreted NS1 proteins of tick-borne encephalitis virus and West Nile virus block dendritic cell activation and effector functions. Camarão AAR, Gern OL, Stegmann F, Mulenge F, Costa B, Saremi B, Jung K, Lepenies B, Kalinke U, Steffen I. Microbiol Spectr. 2023 Sep 14;11(5):e0219223. doi: 10.1128/spectrum.02192-23. Epub ahead of print. PMID: 37707204; PMCID: PMC10581055.
    48. Reverse inflammaging: Long-term effects of HCV cure on biological age. Oltmanns C, Liu Z, Mischke J, Tauwaldt J, Mekonnen YA, Urbanek-Quaing M, Debarry J, Maasoumy B, Wedemeyer H, Kraft ARM, Xu CJ, Cornberg M. J Hepatol. 2023 Jan;78(1):90-98. Pages 90-98, ISSN 0168-8278. https://doi.org/10.1016/j.jhep.2022.08.042.
    49. JAKs and STATs from a Clinical Perspective: Loss-of-Function Mutations, Gain-of-Function Mutations, and Their Multidimensional Consequences Ott N, Faletti L, Heeg M, Andreani V, Grimbacher B. J Clin Immunol. 2023 Aug;43(6):1326-1359. doi: 10.1007/s10875-023-01483-x. Epub 2023 May 4. PMID: 37140667; PMCID: PMC10354173.
    50. A Toolkit for Monitoring Immunoglobulin G Levels from Dried Blood Spots of Patients with Primary Immunodeficiencies. Haberstroh H, Hirsch A, Goldacker S, Zessack N, Warnatz K, Grimbacher B, Salzer U. J Clin Immunol. 2023 Aug;43(6):1185-1192. doi: 10.1007/s10875-023-01464-0. Epub 2023 Mar 21. PMID: 36941491; PMCID: PMC10027597.
    51. Inhibition of IL-17 ameliorates keratinocyte-borne cytokine responses in an in vitro model for house-dust-mite triggered atopic dermatitis. Haertlé J, Kienlin P, Begemann G, Werfel T, Roesner LM. Sci Rep. 2023 Oct 3;13(1):16628. doi: 10.1038/s41598-023-42595-z. PMID: 37789035; PMCID: PMC10547677.
    52. An expanded CRISPR-Cas9-assisted recombineering toolkit for engineering genetically intractable Pseudomonas aeruginosa isolates. Pankratz D, Gomez NO, Nielsen A, Mustafayeva A, Gür M, Arce-Rodriguez F, Nikel PI, Häussler S, Arce-Rodriguez A. Nat Protoc. 2023 Nov;18(11):3253-3288. doi: 10.1038/s41596-023-00882-z. Epub 2023 Oct 5. PMID: 37798358.
    53. High recurrence rate of eczema herpeticum in moderate/severe atopic dermatitis -TREATgermany registry analysis. Traidl S, Heinrich L, Siegels D, Rösner L, Haufe E, Harder I, Abraham S, Ertner K, Kleinheinz A, Schäkel K, Wollenberg A, Effendy I, Quist S, Asmussen A, Wildberger J, Weisshaar E, Wiemers F, Brücher JJ, Weidinger S, Schmitt J, Werfel T; TREATgermany Study Group. J Dtsch Dermatol Ges. 2023 Dec;21(12):1490-1498. doi: 10.1111/ddg.15205. Epub 2023 Oct 9. PMID: 37814394.
    54. RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery. Yang T, Barros-Martins J, Wang Z, Wencker M, Zhang J, Smout J, Gambhir P, Janssen A, Schimrock A, Georgiev H, León-Lara X, Weiss S, Huehn J, Prinz I, Krueger A, Foerster R, Walzer T, Ravens S. Cell Rep. 2023 Oct 31;42(10):113230. doi: 10.1016/j.celrep.2023.113230. Epub 2023 Oct 9. PMID: 37815917.
    55. Future Directions in the Diagnosis and Treatment of APDS and IEI: a Survey of German IEI Centers. Vanselow S, Hanitsch L, Hauck F, Körholz J, Maccari ME, Meinhardt A, Sogkas G, Schuetz C, Grimbacher B. Front Immunol. 2023 Oct 5;14:1279652. doi: 10.3389/fimmu.2023.1279652. PMID: 37868971; PMCID: PMC10588788.
    56. A Phase 3, Randomized Trial of Bulevirtide in Chronic Hepatitis D. Wedemeyer H, Aleman S, Brunetto MR, Blank A, Andreone P, Bogomolov P, Chulanov V, Mamonova N, Geyvandova N, Morozov V, Sagalova O, Stepanova T, Berger A, Manuilov D, Suri V, An Q, Da B, Flaherty J, Osinusi A, Liu Y, Merle U, Schulze Zur Wiesch J, Zeuzem S, Ciesek S, Cornberg M, Lampertico P; MYR 301 Study Group.  N Engl J Med. 2023 Jul 6;389(1):22-32. doi: 10.1056/NEJMoa2213429. Epub 2023 Jun 22. PMID: 37345876.
    57. Alveolar macrophages in tissue homeostasis, inflammation, and infection: evolving concepts of therapeutic targeting. Malainou C, Abdin SM, Lachmann N, Matt U, Herold S. J Clin Invest. 2023 Oct 2;133(19):e170501. doi: 10.1172/JCI170501. PMID: 37781922; PMCID: PMC10541196.
    58. ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality. Sindram E, Caballero-Oteyza A, Kogata N, Chor Mei Huang S, Alizadeh Z, Gámez-Díaz L, Fazlollhi MR, Peng X, Grimbacher B, Way M, Proietti M.  Dis Model Mech. 2023 Jul 1;16(7):dmm050145. doi: 10.1242/dmm.050145. Epub 2023 Jul 20. PMID: 37382373; PMCID: PMC10387347.
    59. Bile acid increase during bulevirtide treatment of hepatitis D is not associated with a decline in HDV RNA. Deterding K, Xu C, Port K, Dietz-Fricke C, Xun J, Maasoumy B, Cornberg M, Wedemeyer H.  J Viral Hepat. 2023 Jul;30(7):597-606. doi: 10.1111/jvh.13831. Epub 2023 Mar 28. PMID: 36924318.
    60. Clinical long-term outcome of hepatitis D compared to hepatitis B monoinfection. Wranke A, Heidrich B, Deterding K, Hupa-Breier KL, Kirschner J, Bremer B, Cornberg M, Wedemeyer H.  Hepatol Int. 2023 Dec;17(6):1359-1367. doi: 10.1007/s12072-023-10575-0. Epub 2023 Oct 3. PMID: 37789170; PMCID: PMC10661878.
    61. Clinical, immunological and molecular findings of 8 patients with typical and atypical severe combined immunodeficiency: identification of 7 novel mutations by whole exome sequencing. Alizadeh Z, Fazlollahi MR, Mazinani M, Badalzadeh M, Heydarlou H, Carapito R, Molitor A, de Oteyza ACG, Proietti M, Bavani MS, Shariat M, Fallahpour M, Movahedi M, Moradi L, Grimbacher B, Bahram S, Pourpak Z.  Genes Immun. 2023 Aug;24(4):207-214. doi: 10.1038/s41435-023-00215-w. Epub 2023 Jul 29. PMID: 37516813.
    62. Common Variable Immunodeficiency: More Pathways than Roads to Rome. Peng XP, Caballero-Oteyza A, Grimbacher B.  Annu Rev Pathol. 2023 Jan 24;18:283-310. doi: 10.1146/annurev-pathmechdis-031521-024229. Epub 2022 Oct 20. PMID: 36266261.
    63. Comparison of Three Eradication Treatment Protocols for Pseudomonas Aeruginosa in Children and Adolescents with Cystic Fibrosis. Schütz K, Grewendorf S, Kontsendorn J, Fuge J, Happle C, Rudolf I, Dopfer C, Sedlacek L, Hansen G, Junge S, Dittrich AM.  Klin Padiatr. 2023 Mar;235(2):75-83. English. doi: 10.1055/a-1996-0074. Epub 2023 Feb 9. PMID: 36758577.
    64. Controlled Attenuation Parameter Is Associated with a Distinct Systemic Inflammatory Milieu after Clearance of HCV Infection. Du Y, Khera T, Liu Z, Tudrujek-Zdunek M, Dworzanska A, Cornberg M, Xu CJ, Tomasiewicz K, Wedemeyer H.  Biomedicines. 2023 May 25;11(6):1529. doi: 10.3390/biomedicines11061529. PMID: 37371624; PMCID: PMC10295384.
    65. Enhanced monitoring and detection of recent genotype 3 hepatitis E virus infection through urine antigen testing. Stahl Y, Kabar I, Heinzow H, Maasoumy B, Bremer B, Wedemeyer H, Schmidt HH, Pietschmann T, Schlevogt B, Behrendt P.  Emerg Microbes Infect. 2023 Dec;12(2):2251598. doi: 10.1080/22221751.2023.2251598. Epub 2023 Aug 31. PMID: 37649441; PMCID: PMC10512750.
    66. Evolutionary Insight into the Association between New Jersey Polyomavirus and Humans. Aghebatrafat AA, Lauber C, Merkel K, Fruth B, Langergraber K, Robbins MM, Wittig RM, Leendertz FH, Calvignac-Spencer S.  Viruses. 2023 Nov 13;15(11):2248. doi: 10.3390/v15112248. PMID: 38005925; PMCID: PMC10675294.
    67. Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry. Rojas-Restrepo J, Sindram E, Zenke S, Haberstroh H, Mitsuiki N, Gabrysch A, Huebscher K, Posadas-Cantera S, Krausz M, Kobbe R, Rohr JC, Grimbacher B, Gámez-Díaz L. J Clin Immunol. 2023 Nov;43(8):2076-2089. doi: 10.1007/s10875-023-01582-9. Epub 2023 Sep 23. Erratum in: J Clin Immunol. 2023 Oct 9;: PMID: 37740092; PMCID: PMC10661720.
    68. GenIA, the Genetic Immunology Advisor database for inborn errors of immunity. Caballero-Oteyza A, Crisponi L, Peng XP, Yauy K, Volpi S, Giardino S, Freeman AF, Grimbacher B, Proietti M.  J Allergy Clin Immunol. 2023 Nov 30:S0091-6749(23)01513-0. doi: 10.1016/j.jaci.2023.11.022. Epub ahead of print. PMID: 38040041.
    69. HDV RNA assays: Performance characteristics, clinical utility, and challenges. Wedemeyer H, Leus M, Battersby TR, Glenn J, Gordien E, Kamili S, Kapoor H, Kessler HH, Lenz O, Lütgehetmann M, Mixson-Hayden T, Simon CO, Thomson M, Westman G, Miller V, Terrault N, Lampertico P; HDV RNA Assays Writing Group at the HBV Forum.  Hepatology. 2023 Aug 28. doi: 10.1097/HEP.0000000000000584. Epub ahead of print. PMID: 37640384.
    70. Interferon-based treatment of chronic hepatitis D. Sandmann L, Wedemeyer H. Liver Int. 2023 Aug;43 Suppl 1:69-79. doi: 10.1111/liv.15410. Epub 2022 Sep 2. PMID: 36002390.
    71. Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen: more than a key mediator of viral persistence. Schulz TF, Freise A, Stein SC.  Curr Opin Virol. 2023 Aug;61:101336. doi: 10.1016/j.coviro.2023.101336. Epub 2023 Jun 16. PMID: 37331160.
    72. Kinetics and predictive value of HBcrAg, HBV RNA and anti-HBc during bulevirtide treatment of chronic HDV-infected patients. Sandmann L, Deterding K, Bremer B, Port K, Cornberg M, Wedemeyer H, Maasoumy B.  J Viral Hepat. 2023 Apr;30(4):283-286. doi: 10.1111/jvh.13804. Epub 2023 Jan 23. PMID: 36648369.
    73. MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice. Gotru SK, Mammadova-Bach E, Sogkas G, Schuhmann MK, Schmitt K, Kraft P, Herterich S, Mamtimin M, Pinarci A, Beck S, Stritt S, Han C, Ren P, Freund JN, Klemann C, Ringshausen FC, Heemskerk JWM, Dietrich A, Nieswandt B, Stoll G, Gudermann T, Braun A.  Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):1494-1509. doi: 10.1161/ATVBAHA.122.318115. Epub 2023 Jun 29. PMID: 37381987.
    74. Next generation sequencing (NGS)-based approach to diagnosing Algerian patients with suspected inborn errors of immunity (IEIs). Peng XP, Al-Ddafari MS, Caballero-Oteyza A, El Mezouar C, Mrovecova P, Dib SE, Massen Z, Smahi MC, Faiza A, Hassaïne RT, Lefranc G, Aribi M, Grimbacher B.  Clin Immunol. 2023 Nov;256:109758. doi: 10.1016/j.clim.2023.109758. Epub 2023 Sep 9. PMID: 37678716.
    75. Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia. Abdin SM, Paasch D, Kloos A, Oliveira MC, Jang MS, Ackermann M, Stamopoulou A, Mroch PJ, Falk CS, von Kaisenberg CS, Schambach A, Heuser M, Moritz T, Hansen G, Morgan M, Lachmann N.  J Immunother Cancer. 2023 Dec 22;11(12):e007705. doi: 10.1136/jitc-2023-007705. PMID: 38135346; PMCID: PMC10749073.
    76. Telomere biology disorders may manifest as common variable immunodeficiency (CVID). Rolles B, Caballero-Oteyza A, Proietti M, Goldacker S, Warnatz K, Camacho-Ordonez N, Prader S, Schmid JP, Vieri M, Isfort S, Meyer R, Kirschner M, Brümmendorf TH, Beier F, Grimbacher B.  Clin Immunol. 2023 Dec;257:109837. doi: 10.1016/j.clim.2023.109837. Epub 2023 Nov 8. PMID: 37944684.
    77. The Cystic Fibrosis Upper and Lower Airway Metagenome. Pienkowska K, Pust MM, Gessner M, Gaedcke S, Thavarasa A, Rosenboom I, Morán Losada P, Minso R, Arnold C, Hedtfeld S, Dorda M, Wiehlmann L, Mainz JG, Klockgether J, Tümmler B.  Microbiol Spectr. 2023 Mar 9;11(2):e0363322. doi: 10.1128/spectrum.03633-22. Epub ahead of print. PMID: 36892308; PMCID: PMC10101124.
    78. The Origin of the Intracellular Silver in Bacteria: A Comprehensive Study using Targeting Gold-Silver Alloy Nanoparticles. Streich C, Stein F, Jakobi J, Ingendoh-Tsakmakidis A, Heine N, Rehbock C, Winkel A, Grade S, Kühnel M, Migunov V, Kovács A, Knura T, Stiesch M, Sures B, Barcikowski S. Adv Healthc Mater. 2023 Dec;12(30):e2302084. doi: 10.1002/adhm.202302084. Epub 2023 Sep 17. PMID: 37661312.
    79. The role of nuclear pores and importins for herpes simplex virus infection. Döhner K, Serrero MC, Sodeik B.  Curr Opin Virol. 2023 Oct;62:101361. doi: 10.1016/j.coviro.2023.101361. Epub 2023 Sep 4. PMID: 37672874.
    80. Treating hepatitis D with bulevirtide – Real-world experience from 114 patients. Dietz-Fricke C, Tacke F, Zöllner C, Demir M, Schmidt HH, Schramm C, Willuweit K, Lange CM, Weber S, Denk G, Berg CP, Grottenthaler JM, Merle U, Olkus A, Zeuzem S, Sprinzl K, Berg T, van Bömmel F, Wiegand J, Herta T, Seufferlein T, Zizer E, Dikopoulos N, Thimme R, Neumann-Haefelin C, Galle PR, Sprinzl M, Lohse AW, Schulze Zur Wiesch J, Kempski J, Geier A, Reiter FP, Schlevogt B, Gödiker J, Hofmann WP, Buggisch P, Kahlhöfer J, Port K, Maasoumy B, Cornberg M, Wedemeyer H, Deterding K.  JHEP Rep. 2023 Mar 15;5(4):100686. doi: 10.1016/j.jhepr.2023.100686. PMID: 37025462; PMCID: PMC10071092.
    81. An evaluation of an open access iPSC training course: „How to model interstitial lung disease using patient-derived iPSCs“. Schweikert A, Kenny S, Oglesby I, Glasgow A, de Santi C, Gensch I, Lachmann N, Desroziers T, Fletcher C, Snijders D, Nathan N, Hurley K; COST Open-ILD Group Management Committee. Stem Cell Res Ther. 2023 Dec 20;14(1):377. doi: 10.1186/s13287-023-03598-9. PMID: 38124115; PMCID: PMC10734099.
    82. CVID-Associated B Cell Activating Factor Receptor Variants Change Receptor Oligomerization, Ligand Binding, and Signaling Responses. Block V, Sevdali E, Recher M, Abolhassani H, Hammarstrom L, Smulski CR, Baronio M, Plebani A, Proietti M, Speletas M, Warnatz K, Voll RE, Lougaris V, Schneider P, Eibel H.  J Clin Immunol. 2023 Feb;43(2): 391-405. Epub 2022 Oct 29.
    83. Clinical, immunological and molecular findings of 8 patients with typical and atypical severe combined immunodeficiency: identification of 7 novel mutations by whole exome sequencing. Alizadeh Z, Fazlollahi MR, Mazinani M, Badalzadeh M, Heydarlou H, Carapito R, Molitor A, de Oteyza ACG, Proietti M, Bavani MS, Shariat M, Fallahpour M, Movahedi M, Moradi L, Grimbacher B, Bahram S, Pourpak Z. Genes Immun. 2023 Aug;24(4):207-214. Epub 2023 Jul 29.
    84. Fecal Immunoglobulin Levels as a Modifier of the Gut Microbiome in Patients with Common Variable Immunodeficiency. J Clin Immunol. Nöltner C, Bulashevska A, Hübscher K, Haberstroh H, Grimbacher B, Proietti M.  J Clin Immunol. 2023 Aug;43(6):1208-1220. doi: 10.1007/s10875-023-01469-9. Epub 2023 Mar 24.
    85. ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality. Sindram E, Caballero-Oteyza A, Kogata N, Chor Mei Huang S, Alizadeh Z, Gámez-Díaz L, Fazlollhi MR, Peng X, Grimbacher B, Way M, Proietti M. Dis Model Mech. 2023 Jul 1;16(7):dmm050145. Epub 2023 Jul 20.
    86. Kinetics and predictive value of HBcrAg, HBV RNA and anti-HBc during bulevirtide treatment of chronic HDV-infected patients
      Sandmann, L.Deterding, K.Bremer, B.Port, K.Cornberg, M.Wedemeyer, H.Maasoumy, B. J Viral Hepat. 2023 Apr;30(4):283-286. doi: 10.1111/jvh.13804. Epub 2023 Jan 23.
    87. Transcriptome Dynamics of Pseudomonas aeruginosa during Transition from Overlapping To Non-Overlapping Cell Cycles
      Kathrin Alpers , Elisabeth Vatareck , Lothar Gröbe , Mathias Müsken , Maren Scharfe , Susanne Häussler , Jürgen Tomasch
      mSystems. 2023 Apr 27;8(2):e0113022. doi: 10.1128/msystems.01130-22. Epub 2023 Feb 14.
    88. Quality-of-life scores improve after 96 weeks of PEG-IFNa-2a treatment of hepatitis D: An analysis of the HIDIT-II trial
      Dinkelborg, K.Kahlhofer, J.Dorge, P.Yurdaydin, C.Hardtke, S.Caruntu, F. A.Curescu, M. G.Yalcin, K.Akarca, U. S.Gurel, S.Zeuzem, S.Erhardt, A.Luth, S.Papatheodoridis, G. V.Keskin, O.Port, K.Radu, M.Celen, M. K.Idilman, R.Weber, K.Stift, J.Wittkop, U.Heidrich, B.Mederacke, I.von der Leyen, H.Dienes, H. P.Cornberg, M.Koch, A.Manns, M. P.Wedemeyer, H.Deterding, K.Hidit- Study Team
      Liver Int. 2023 Aug;43(8):1663-1676. doi: 10.1111/liv.15602. Epub 2023 May 15.
    89. MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice
      Gotru, S. K.Mammadova-Bach, E.Sogkas, G.Schuhmann, M. K.Schmitt, K.Kraft, P.Herterich, S.Mamtimin, M.Pinarci, A.Beck, S.Stritt, S.Han, C.Ren, P.Freund, J. N.Klemann, C.Ringshausen, F. C.Heemskerk, J. W. M.Dietrich, A.Nieswandt, B.Stoll, G.Gudermann, T.Braun, A.
      Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):1494-1509. doi: 10.1161/ATVBAHA.122.318115. Epub 2023 Jun 29.
    90. A Toolkit for Monitoring Immunoglobulin G Levels from Dried Blood Spots of Patients with Primary Immunodeficiencies
      Haberstroh, H.Hirsch, A.Goldacker, S.Zessack, N.Warnatz, K.Grimbacher, B.Salzer, U.
      J Clin Immunol. 2023 Aug;43(6):1185-1192. doi: 10.1007/s10875-023-01464-0. Epub 2023 Mar 21.
    91. JAKs and STATs from a Clinical Perspective: Loss-of-Function Mutations, Gain-of-Function Mutations, and Their Multidimensional Consequences J Clin Immunol. 2023 Aug;43(6):1326-1359. doi: 10.1007/s10875-023-01483-x. Epub 2023 May 4. Nils Ott , Laura Faletti , Maximilian Heeg , Virginia Andreani , Bodo Grimbacher
    92. Interferon-based treatment of chronic hepatitis D
      Sandmann, L.Wedemeyer, H. Liver Int. 2023 Aug:43 Suppl 1:69-79. doi: 10.1111/liv.15410. Epub 2022 Sep 2.
    93. The Origin of the Intracellular Silver in Bacteria: A Comprehensive Study using Targeting Gold-Silver Alloy Nanoparticles
      Streich, C.Stein, F.Jakobi, J.Ingendoh-Tsakmakidis, A.Heine, N.Rehbock, C.Winkel, A.Grade, S.Kühnel, M.Migunov, V.Kovács, A.Knura, T.Stiesch, M.Sures, B.Barcikowski, S.
      Adv Healthc Mater. 2023 Dec;12(30):e2302084. doi: 10.1002/adhm.202302084. Epub 2023 Sep 17.
    94. Status of HIV and comorbidities in refugees with HIV from Ukraine
      Ahrenstorf, G.Dopfer-Jablonka, A.Joean, O.Knuth, C.Silchmueller, M.Thiele, T.Ringshausen, F. C.Slevogt, H.Witte, T.Behrens, G. M. N.
      HIV Med. 2024 Apr;25(4):479-483. doi: 10.1111/hiv.13597. Epub 2023 Dec 3.
    95. Rituximab to treat prolidase deficiency due to a novel pathogenic copy number variation in PEPD
      Atschekzei, F.Fedchenko, M.Elsayed, A.Dubrowinskaja, N.Graalmann, T.Ringshausen, F. C.Witte, T.Sogkas, G.
      RMD Open. 2023 Dec 7;9(4):e003507. doi: 10.1136/rmdopen-2023-003507.
    96. Efficacy of dupilumab for the treatment of severe skin disease in cytotoxic T lymphocyte antigen-4 insufficiency: A role of type 2 inflammation?
      Arruda, L. K.Cordeiro, D. L.Langer, S. S.Koenigham-Santos, M.Calado, R. T.Dias, M. M.Anhesini, L. R.Oliveira, J. B.Grimbacher, B.Ferriani, M. P. L.
      J Allergy Clin Immunol Glob. 2022 Sep 22;2(1):114-117. doi: 10.1016/j.jacig.2022.08.004. eCollection 2023 Feb.
    97. Birch pollen extract enhances human cytomegalovirus replication in monocyte-derived dendritic cells
      Fneish, Z.Becker, J.Mulenge, F.Costa, B.Krajewski, L.Duran, V.Ziegler, A.Sommer, V.Traidl-Hoffmann, C.Gilles, S.Kalinke, U.
      Allergy. 2023 Feb;78(2):543-546. doi: 10.1111/all.15497. Epub 2022 Sep 13.
    98. Pleural CD14+ monocytes/macrophages of healthy adolescents show a high expression of metallothionein family genes
      Schukfeh, N.Liu, B.DeLuca, D. S.Tumpara, S.Nikolin, C.Immenschuh, S.Ure, B. M.Kuebler, J. F.Welte, T.Viemann, D.Janciauskiene, S. M.Vieten, G. Eur J Immunol. 2023 Jan;53(1):e2250019. doi: 10.1002/eji.202250019. Epub 2022 Nov 18
    99. Tralokinumab treatment improves the skin microbiota by increasing the microbial diversity in adults with moderate-to-severe atopic dermatitis: Analysis of microbial diversity in ECZTRA 1, a randomized controlled trial. Lisa A Beck , Thomas Bieber , Stephan Weidinger , Marie Tauber , Hidehisa Saeki , Alan D Irvine , Lawrence F Eichenfield , Thomas Werfel , Petra Arlert , Li Jiang , Mads Røpke , Amy S Paller J Am Acad Dermatol. 2023 Apr;88(4):816-823. doi: 10.1016/j.jaad.2022.11.047. Epub 2022 Dec 5.
    100. Treating hepatitis D with bulevirtide – Real-world experience from 114 patients. Christopher Dietz-Fricke , Frank Tacke , Caroline Zöllner , Münevver Demir , Hartmut H Schmidt , Christoph Schramm , Katharina Willuweit , Christian M Lange , Sabine Weber , Gerald Denk , Christoph P Berg , Julia M Grottenthaler , Uta Merle , Alexander Olkus , Stefan Zeuzem , Kathrin Sprinzl , Thomas Berg , Florian van Bömmel , Johannes Wiegand , Toni Herta , Thomas Seufferlein , Eugen Zizer , Nektarios Dikopoulos , Robert Thimme , Christoph Neumann-Haefelin , Peter R Galle , Martin Sprinzl , Ansgar W Lohse , Julian Schulze Zur Wiesch , Jan Kempski , Andreas Geier , Florian P Reiter , Bernhard Schlevogt , Juliana Gödiker , Wolf Peter Hofmann , Peter Buggisch , Julia Kahlhöfer , Kerstin Port , Benjamin Maasoumy , Markus Cornberg , Heiner Wedemeyer , Katja Deterding JHEP Rep. 2023 Mar 15;5(4):100686. doi: 10.1016/j.jhepr.2023.100686. eCollection 2023 Apr.
    101. Hepatitis D virus infection: Pathophysiology, epidemiology and treatment. Report from the first international delta cure meeting 2022
      JHEP Rep. 2023 Jun 28;5(9):100818. doi: 10.1016/j.jhepr.2023.100818. eCollection 2023 Sep.
      Pietro Lampertico , Elisabetta Degasperi , Lisa Sandmann , Heiner Wedemeyer ; Delta Cure 2022 Working Group
    102. A Toolkit for Monitoring Immunoglobulin G Levels from Dried Blood Spots of Patients with Primary Immunodeficiencies. Haberstroh H, Hirsch A, Goldacker S, Zessack N, Warnatz K, Grimbacher B, Salzer U.  J Clin Immunol. 2023 Aug;43(6):1185-1192. doi: 10.1007/s10875-023-01464-0. Epub 2023 Mar 21.
    103. Viral determinants influencing intra- and intercellular communication in cytomegalovirus infection. Szymanska-de Wijs K, Dezeljin M, Bogdanow B, Messerle M.Curr Opin Virol. 2023 Jun;60:101328. doi: 10.1016/j.coviro.2023.101328. Epub 2023 Apr 7.PMID: 37031486 Review.
    104. Targeted mutagenesis of the herpesvirus fusogen central helix captures transition states. Zhou M, Vollmer B, Machala E, Chen M, Grünewald K, Arvin AM, Chiu W, Oliver SL. Nat Commun. 2023 Dec 2;14(1):7958.
    105. CVID-Associated B Cell Activating Factor Receptor Variants Change Receptor Oligomerization, Ligand Binding, and Signaling Responses V. Block, E. Sevdali, M. Recher, H. Abolhassani, L. Hammarstrom, C. R. Smulski, et al. J Clin Immunol 2023 Vol. 43 Issue 2 Pages 391-405 Accession Number: 36308663 PMCID: PMC9616699 DOI: 10.1007/s10875-022-01378-3
  1. Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Weber T, Potthoff J, Bizu S, Labuhn M, Dold L, Schoofs T, Horning M, Ercanoglu MS, Kreer C, Gieselmann L, Vanshylla K, Langhans B, Janicki H, Ströh LJ, Knops E, Nierhoff D, Spengler U, Kaiser R, Bjorkman PJ, Krey T, Bankwitz D, Pfeifer N, Pietschmann T, Flyak AI, Klein F. Immunity. 2022 Feb 8;55(2):341-354.e7.
  2. Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination. Hammerschmidt SI, Thurm C, Bošnjak B, Bernhardt G, Reinhold A, Willenzon S, Ritter C, Reinhold D, Schraven B, Förster R.  Eur J Immunol. 2022 Feb;52(2):356-359.
  3. The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses. Schreiber A, Viemann D, Schöning J, Schloer S, Mecate Zambrano A, Brunotte L, Faist A, Schöfbänker M, Hrincius E, Hoffmann H, Hoffmann M, Pöhlmann S, Rescher U, Planz O, Ludwig S.  Cell Mol Life Sci. 2022 Jan 10;79(1):65.
  4. Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19. Sahajpal NS, Jill Lai CY, Hastie A, Mondal AK, Dehkordi SR, van der Made CI, Fedrigo O, Al-Ajli F, Jalnapurkar S, Byrska-Bishop M, Kanagal-Shamanna R, Levy B, Schieck M, Illig T, Bacanu SA, Chou JS, Randolph AG, Rojiani AM, Zody MC, Brownstein CA, Beggs AH, Bafna V, Jarvis ED, Hoischen A, Chaubey A, Kolhe R; COVID19hostgenomesv consortium.  iScience. 2022 Jan 10:103760.
  5. Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors. Ackermann M, Rafiei Hashtchin A, Manstein F, Carvalho Oliveira M, Kempf H, Zweigerdt R, Lachmann N. Nat Protoc. 2022 Jan 17.
  6. Dual Effect: High NADH Levels Contribute to Efflux-Mediated Antibiotic Resistance but Drive Lethality Mediated by Reactive Oxygen Species. Arce-Rodríguez A, Pankratz D, Preusse M, Nikel PI, Häussler S.  mBio. 2022 Jan 18:e0243421.
  7. Wahrnehmung der Corona-Pandemie durch Neurodermitispatienten – Ergebnisse aus dem Neurodermitisregister TREATgermany. Helmert C, Siegels D, Haufe E, Abraham S, Heratizadeh A, Kleinheinz A, Harder I, Schäkel K, Effendy I, Wollenberg A, Sticherling M, Stahl M, Worm M, Schwichtenberg U, Schwarz B, Rossbacher J, Buck PM, Schenck F, Werfel T, Weidinger S, Schmitt J; das TREATgermany Studienteam. J Dtsch Dermatol Ges. 2022 Jan;20(1):45-58.
  8. The biliary microbiome in ischaemic-type biliary lesions can be shaped by stenting but is resilient to antibiotic treatment. Klein F, Wellhöner F, Plumeier I, Kahl S, Chhatwal P, Vital M, Voigtländer T, Pieper DH, Manns MP, Lenzen H, Solbach P, Heidrich B.  Liver Int. 2022 Feb 13.
  9. Clinical development and approval of COVID-19 vaccines. Kalinke U, Barouch DH, Rizzi R, Lagkadinou E, Türeci Ö, Pather S, Neels P.  Expert Rev Vaccines. 2022 Feb 14.
  10. Ubiquitin-modifying enzymes as regulators of colitis. Ruan J, Schlüter D, Naumann M, Waisman A, Wang X. Trends Mol Med. 2022 Feb 15:S1471-4914(22)00025-9.
  11. Evidence for an Adult-Like Type 1-Immunity Phenotype of Vδ1, Vδ2 and Vδ3 T Cells in Ghanaian Children With Repeated Exposure to Malaria. León-Lara X, Yang T, Fichtner AS, Bruni E, von Kaisenberg C, Eiz-Vesper B, Dodoo D, Adu B, Ravens S. Front Immunol. 2022 Feb 17;13:807765
  12. Common Variable Immunodeficiency-Associated Cancers: The Role of Clinical Phenotypes, Immunological and Genetic Factors. Bruns L, Panagiota V, von Hardenberg S, Schmidt G, Adriawan IR, Sogka E, Hirsch S, Ahrenstorf G, Witte T, Schmidt RE, Atschekzei F, Sogkas G. Front Immunol. 2022 Feb 17;13:742530.
  13. Pseudomonas aeruginosa Is More Tolerant Under Biofilm Than Under Planktonic Growth Conditions: A Multi-Isolate Survey. Thöming JG, Häussler S.  Front Cell Infect Microbiol. 2022 Feb 28;12:851784.
  14. T cell receptor sequencing specifies psoriasis as a systemic and atopic dermatitis as a skin-focused, allergen-driven disease. Roesner LM, Farag AK, Pospich R, Traidl S, Werfel T. Allergy. 2022 Mar 7.
  15. Human cytomegalovirus forms phase-separated compartments at viral genomes to facilitate viral replication. Caragliano E, Bonazza S, Frascaroli G, Tang J, Soh TK, Grünewald K, Bosse JB, Brune W. Cell Rep. 2022 Mar 8;38(10):110469.
  16. IRIS: Infection with RespIratory Syncytial Virus in infants-a prospective observational cohort study. Wetzke M, Funken D, Lange M, Bejo L, Haid S, Monteiro JGT, Schütz K, Happle C, Schulz TF, Seidenberg J, Pietschmann T, Hansen G. BMC Pulm Med. 2022 Mar 15;22(1):88.
  17. The Human Liver-Expressed Lectin CD302 Restricts Hepatitis C Virus Infection. Reinecke B, Frericks N, Lauber C, Dinkelborg K, Matthaei A, Vondran FWR, Behrendt P, Haid S, Brown RJP, Pietschmann T. J Virol. 2022 Mar 17:e0199521.
  18. Pseudomonas aeruginosa post-translational responses to elevated c-di-GMP levels. Bense S, Witte J, Preuße M, Koska M, Pezoldt L, Dröge A, Hartmann O, Müsken M, Schulze J, Fiebig T, Bähre H, Felgner S, Pich A, Häussler S. Mol Microbiol. 2022 Apr 1.
  19. Evolution of biofilm-adapted gene expression profiles in lasR-deficient clinical Pseudomonas aeruginosa isolates. Jeske A, Arce-Rodriguez A, Thöming JG, Tomasch J, Häussler S. NPJ Biofilms Microbiomes. 2022 Feb 14;8(1):6.
  20. Challenges of CRISPR-Based Gene Editing in Primary T Cells. Rezalotfi A, Fritz L, Förster R, Bošnjak B. Int J Mol Sci. 2022 Feb 1;23(3):1689.
  21. Imaging dendritic cell functions. Bošnjak B, Do KTH, Förster R, Hammerschmidt SI. Immunol Rev. 2022 Mar;306(1):137-163.
  22. Ovarian tumor domain proteases in pathogen infection. Schlüter D, Schulze-Niemand E, Stein M, Naumann M.  Trends Microbiol. 2022 Jan;30(1):22-33.
  23. Beneficial and detrimental functions of microglia during viral encephalitis. Waltl I, Kalinke U. Trends Neurosci. 2022 Feb;45(2):158-170.
  24. Dysregulated PI3K Signaling in B Cells of CVID Patients. Harder I, Münchhalfen M, Andrieux G, Boerries M, Grimbacher B, Eibel H, Maccari ME, Ehl S, Wienands J, Jellusova J, Warnatz K, Keller B. Cells. 2022 Jan 28;11(3):464.
  25. Longitudinal Tracking of Immune Responses in COVID-19 Convalescents Reveals Absence of Neutralization Activity Against Omicron and Staggered Impairment to Other SARS-CoV-2 Variants of Concern. Odak I, Schultze-Florey CR, Hammerschmidt SI, Ritter C, Willenzon S, Friedrichsen M, Ravens I, Sikora R, Bayir LM, Gutierrez Jauregui R, Bernhardt G, Stankov MV, Cossmann A, Hansen G, Krey T, Cornberg M, Koenecke C, Behrens GMN, Bošnjak B, Förster R.  Front Immunol. 2022 Mar 14;13:863039. doi: 10.3389/fimmu.2022.863039. PMID: 35359969; PMCID: PMC8964088.
  26. Critical Assessment of Metagenome Interpretation: the second round of challenges. Meyer F, Fritz A, Deng ZL, Koslicki D, Lesker TR, Gurevich A, Robertson G, Alser M, Antipov D, Beghini F, Bertrand D, Brito JJ, Brown CT, Buchmann J, Buluç A, Chen B, Chikhi R, Clausen PTLC, Cristian A, Dabrowski PW, Darling AE, Egan R, Eskin E, Georganas E, Goltsman E, Gray MA, Hansen LH, Hofmeyr S, Huang P, Irber L, Jia H, Jørgensen TS, Kieser SD, Klemetsen T, Kola A, Kolmogorov M, Korobeynikov A, Kwan J, LaPierre N, Lemaitre C, Li C, Limasset A, Malcher-Miranda F, Mangul S, Marcelino VR, Marchet C, Marijon P, Meleshko D, Mende DR, Milanese A, Nagarajan N, Nissen J, Nurk S, Oliker L, Paoli L, Peterlongo P, Piro VC, Porter JS, Rasmussen S, Rees ER, Reinert K, Renard B, Robertsen EM, Rosen GL, Ruscheweyh HJ, Sarwal V, Segata N, Seiler E, Shi L, Sun F, Sunagawa S, Sørensen SJ, Thomas A, Tong C, Trajkovski M, Tremblay J, Uritskiy G, Vicedomini R, Wang Z, Wang Z, Wang Z, Warren A, Willassen NP, Yelick K, You R, Zeller G, Zhao Z, Zhu S, Zhu J, Garrido-Oter R, Gastmeier P, Hacquard S, Häußler S, Khaledi A, Maechler F, Mesny F, Radutoiu S, Schulze-Lefert P, Smit N, Strowig T, Bremges A, Sczyrba A, McHardy AC. Nat Methods. 2022 Apr;19(4):429-440.
  27. Strain identification and quantitative analysis in microbial communities. Ghazi AR, Münch PC, Chen D, Jensen J, Huttenhower C.  J Mol Biol. 2022 Apr 7:167582.
  28. Diagnostic Yield and Therapeutic Consequences of Targeted Next-Generation Sequencing in Sporadic Primary Immunodeficiency. Sogkas G, Dubrowinskaja N, Schütz K, Steinbrück L, Götting J, Schwerk N, Baumann U, Grimbacher B, Witte T, Schmidt RE, Atschekzei F. Int Arch Allergy Immunol. 2022;183(3):337-349.
  29. Deubiquitinating enzymes (DUBs): decipher underlying basis of neurodegenerative diseases. Liu B, Ruan J, Chen M, Li Z, Manjengwa G, Schlüter D, Song W, Wang X.  Mol Psychiatry. 2022 Jan;27(1):259-268.
  30. Specific T cells targeting Staphylococcus aureus fibronectin-binding protein 1 induce a type 2/type 1 inflammatory response in sensitized atopic dermatitis patients. Farag AK, Roesner LM, Wieschowski S, Heratizadeh A, Eiz-Vesper B, Kwok WW, Valenta R, Werfel T.  Allergy. 2022 Apr;77(4):1245-1253.
  31. High plasmidome diversity of extended-spectrum beta-lactam-resistant Escherichia coli isolates collected during one year in one community hospital. Neffe L, Abendroth L, Bautsch W, Häussler S, Tomasch J. Genomics. 2022 Apr 18:110368.
  32. The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway. Yang X, Ali S, Zhao M, Richter L, Schäfer V, Schliehe-Diecks J, Frank M, Qi J, Larsen PK, Skerra J, Islam H, Wachtmeister T, Alter C, Huang A, Bhatia S, Köhrer K, Kirschning C, Weighardt H, Kalinke U, Kalscheuer R, Uhrberg M, Scheu S. Front Immunol. 2022 Apr 8;13:856230.
  33. Toll-like receptors matter: plasmacytoid dendritic cells in COVID-19. Becker J, Kalinke U. EMBO J. 2022 Apr 26:e111208. doi: 10.15252/embj.2022111208. Epub ahead of print.
  34. Genome wide association study of Escherichia coli bloodstream infection isolates identifies genetic determinants for the portal of entry but not fatal outcome. Denamur E, Condamine B, Esposito-Farèse M, Royer G, Clermont O, Laouenan C, Lefort A, de Lastours V, Galardini M; COLIBAFI; SEPTICOLI groups. PLoS Genet. 2022 Mar 24
  35. An integrated analysis of herpes virus infections from eight randomised clinical studies of baricitinib in adults with moderate to severe atopic dermatitis.  Werfel T, Irvine AD, Bangert C, Seneschal J, Grond S, Cardillo T, Brinker D, Zhong J, Riedl E, Wollenberg A. J Eur Acad Dermatol Venereol. 2022 May 1.
  36. OMIP-084: 28-color full spectrum flow cytometry panel for the comprehensive analysis of human γδ T cells. Barros-Martins J, Bruni E, Fichtner AS, Cornberg M, Prinz I. Cytometry A. 2022 May 6.
  37. The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses eLife. Manutea C Serrero, Virginie Girault, Sebastian Weigang, Todd M Greco, Ana Ramos Nascimento, Fenja Anderson, Antonio Piras, Ana Hickford Martinez, Jonny Hertzog, Anne Binz, Anja Pohlmann, Ute Prank, Jan Rehwinkel, Rudolf Bauerfeind, Ileana M Cristea, Andreas Pichlmair, Georg Kochs, Beate Sodeik. eLife
  38. Herpesvirus Replication Compartments: Dynamic Biomolecular Condensates? Enrico Caragliano, Wolfram Brune, Jens B. Bosse, Viruses
  39. IgA+ memory B cells are significantly increased in patients with asthma and small airways dysfunction. Habener A, Grychtol R, Gaedcke S, DeLuca D, Dittrich AM, Happle C, Abdo M, Watz H, Pedersen F, König IR, Thiele D, Kopp MV, von Mutius E, Bahmer T, Rabe KF, Meyer-Bahlburg A, Hansen G; ALLIANCE study group as part of the German Center for Lung Research (DZL). Eur Respir J.
  40. Impact of gut microenvironment on epigenetic signatures of intestinal T helper cell subsets. Sasidharan Nair V, Heredia M, Samsom J, Huehn J.  Immunol Lett.
  41. Rapid and accurate identification of ribosomal RNA sequences via deep learning. Deng ZL, Münch PC, Mreches R, McHardy AC. Nucleic Acids Res.
  42. The unconventional way out – Egress of HCMV through multiviral bodies. Wedemann L, Flomm FJ, Bosse JB. Mol Microbiol.
  43. Diversities of allergic pathologies and their modifiers: Report from the second DGAKI-JSA meeting. Asano K, Tamari M, Zuberbier T, Yasudo H, Morita H, Fujieda S, Nakamura Y, Traidl S, Hamelmann E, Raap U, Babina M, Nagase H, Okano M, Katoh N, Ebisawa M, Renz H, Izuhara K, Worm M. Allergol Int.
  44. PML Alternative Splice Products Differentially Regulate HAdV Productive Infection. Mai J, Stubbe M, Hofmann S, Masser S, Dobner T, Boutell C, Groitl P, Schreiner S. Microbiol Spectr.
  45. Target capture sequencing reveals a monoclonal outbreak of respiratory syncytial virus B infections among adult hematologic patients. Baier C, Huang J, Reumann K, Indenbirken D, Thol F, Koenecke C, Ebadi E, Heim A, Bange FC, Haid S, Pietschmann T, Fischer N. Antimicrob Resist Infect Control.
  46. A Hepatitis C virus genotype 1b post-transplant isolate with high replication efficiency in cell culture and its adaptation to infectious virus production in vitro and in vivo. Heuss C, Rothhaar P, Burm R, Lee JY, Ralfs P, Haselmann U, Ströh LJ, Colasanti O, Tran CS, Schäfer N, Schnitzler P, Merle U, Bartenschlager R, Patel AH, Graw F, Krey T, Laketa V, Meuleman P, Lohmann V. PLoS Pathog.
  47. Testing and isolation to prevent overloaded healthcare facilities and reduce death rates in the SARS-CoV-2 pandemic in Italy. Bandyopadhyay A, Schips M, Mitra T, Khailaie S, Binder SC, Meyer-Hermann M. Commun Med (Lond).
  48. Targeted biallelic integration of an inducible Caspase 9 suicide gene in iPSCs for safer therapies. Wunderlich S, Haase A, Merkert S, Jahn K, Deest M, Frieling H, Glage S, Korte W, Martens A, Kirschning A, Zeug A, Ponimaskin E, Göhring G, Ackermann M, Lachmann N, Moritz T, Zweigerdt R, Martin U. Mol Ther Methods Clin Dev.
  49. Altered nasal microbiota in asthmatic patients is not related to changes in secretory immunity in the nasopharynx. Pausder A, Mras P, Hoenicke L, Waldburg N, Lesker TR, Schreiber J, Strowig T, Boehme JD, Bruder D. Clin Exp Allergy.
  50. Evaluation of Laboratory and Sonographic Parameters for Detection of Portal Hypertension in Patients with Common Variable Immunodeficiency. Globig AM, Strohmeier V, Surabattula R, Leeming DJ, Karsdal MA, Heeg M, Kindle G, Goldacker S, von Spee-Mayer C, Proietti M, Bausch B, Bettinger D, Schultheiß M, Thimme R, Schuppan D, Warnatz K. J Clin Immunol.
  51. ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives. Waqas SF, Sohail A, Nguyen AHH, Usman A, Ludwig T, Wegner A, Malik MNH, Schuchardt S, Geffers R, Winterhoff M, Merkert S, Martin U, Olmer R, Lachmann N, Pessler F. Clin Transl Med. 2022
  52. The impact of the first COVID-19 wave on office-based dermatological care in Germany: a focus on diagnosis, therapy and prescription of biologics. Nordhorn I, Weiss D, Werfel T, Zink A, Schielein MC, Traidl S. Eur J Dermatol.
  53. Intermittent bulk release of human cytomegalovirus. Flomm FJ, Soh TK, Schneider C, Wedemann L, Britt HM, Thalassinos K, Pfitzner S, Reimer R, Grünewald K, Bosse JB. PLoS Pathog. 2022 Aug 4
  54. Single-cell profiles reveal distinctive immune response in atopic dermatitis in contrast to psoriasis. Zhang B, Roesner LM, Traidl S, Koeken VACM, Xu CJ, Werfel T, Li Y. Allergy. 2022 Aug 20.
  55. BNT162b2-boosted immune responses six months after heterologous or homologous ChAdOx1nCoV-19/BNT162b2 vaccination against COVID-19. Behrens GMN, Barros-Martins J, Cossmann A, Ramos GM, Stankov MV, Odak I, Dopfer-Jablonka A, Hetzel L, Köhler M, Patzer G, Binz C, Ritter C, Friedrichsen M, Schultze-Florey C, Ravens I, Willenzon S, Bubke A, Ristenpart J, Janssen A, Ssebyatika G, Krähling V, Bernhardt G, Hoffmann M, Pöhlmann S, Krey T, Bošnjak B, Hammerschmidt SI, Förster R. Nat Commun. 2022 Aug 18.
  56. The dark side of Tregs during aging. Palatella M, Guillaume SM, Linterman MA, Huehn J.  Front Immunol. 2022 Aug 9
  57. GBA-associated PD: chances and obstacles for targeted treatment strategies. Höglinger G, Schulte C, Jost WH, Storch A, Woitalla D, Krüger R, Falkenburger B, Brockmann K. J Neural Transm (Vienna). 2022 Sep;129(9):1219-1233.
  58. Safety and efficacy of bulevirtide in combination with tenofovir disoproxil fumarate in patients with hepatitis B virus and hepatitis D virus coinfection (MYR202): a multicentre, randomised, parallel-group, open-label, phase 2 trial. Wedemeyer H, Schöneweis K, Bogomolov P, Blank A, Voronkova N, Stepanova T, Sagalova O, Chulanov V, Osipenko M, Morozov V, Geyvandova N, Sleptsova S, Bakulin IG, Khaertynova I, Rusanova M, Pathil A, Merle U, Bremer B, Allweiss L, Lempp FA, Port K, Haag M, Schwab M, Zur Wiesch JS, Cornberg M, Haefeli WE, Dandri M, Alexandrov A, Urban S. Lancet Infect Dis. 2022 Sep 13:S1473-3099(22)00318-8.
  59. Inflammatory perturbations in early life long-lastingly shape the transcriptome and TCR repertoire of the first wave of regulatory T cells Juhao Yang1,2†, Mangge Zou1†, Xiaojing Chu3, Stefan Floess1, Yang Li3, Michael Delacher4,5 and Jochen Huehn1,6* Front. Immunol.
  60. Hide and seek with SARS-CoV-2: spike receptor-binding domain-specific memory B cells still recognize Omicron variant. Signal Transduct Target Ther. Odak I, Förster R, Bošnjak B.  2022 Oct 2;7(1):343.
  61. Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Patients with Cystic Fibrosis and One or Two F508del Alleles. Graeber SY, Renz DM, Stahl M, Pallenberg ST, Sommerburg O, Naehrlich L, Berges J, Dohna M, Ringshausen FC, Doellinger F, Vitzthum C, Röhmel J, Allomba C, Hämmerling S, Barth S, Rückes-Nilges C, Wielpütz MO, Hansen G, Vogel-Claussen J, Tümmler B, Mall MA, Dittrich AM.  Am J Respir Crit Care Med. 2022 Aug 1;206(3):311-320.
  62. T-cell receptor sequencing specifies psoriasis as a systemic and atopic dermatitis as a skin-focused, allergen-driven disease. Roesner LM, Farag AK, Pospich R, Traidl S, Werfel T.  Allergy. 2022 Sep;77(9):2737-2747. Epub 2022 Mar 14.
  63. Transcriptional Profiling of Pseudomonas aeruginosa Infections. Thöming JG, Häussler S.  Adv Exp Med Biol. 2022;1386:303-323.
  64. Opportunities and Challenges of Data-Driven Virus Discovery. Lauber C, Seitz S. Biomolecules. 2022 Aug 4;12(8):1073.
  65. The Tetraspanin CD81 Is a Host Factor for Chikungunya Virus Replication. Lasswitz L, Zapatero-Belinchón FJ, Moeller R, Hülskötter K, Laurent T, Carlson LA, Goffinet C, Simmons G, Baumgärtner W, Gerold G. mBio. 2022 Jun 28;13(3):e0073122.Epub 2022 May 25.
  66. The ABACHAI clinical trial protocol: Safety and efficacy of abatacept (s.c.) in patients with CTLA-4 insufficiency or LRBA deficiency: A non controlled phase 2 clinical trial. Krausz M, Uhlmann A, Rump IC, Ihorst G, Goldacker S, Sogkas G, Posadas-Cantera S, Schmidt R, Feißt M, Alsina L, Dybedal I, Recher M, Warnatz K, Grimbacher B. Contemp Clin Trials Commun. 2022 Sep 24;30:101008.
  67.  CTLA-4 Insufficiency due to a Novel CTLA-4 Deletion, Identified through Copy Number Variation Analysis. Olfe L, von Hardenberg S, Hofmann W, Auber B, Baumann U, Beier R, Adriawan IR, Atschekzei F, Witte T, Sogkas G. Int Arch Allergy Immunol. 2022 Oct 21:1-9. Epub ahead of print.
  68. Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency-Associated Villous Atrophy and Norovirus Infection. Strohmeier V, Andrieux G, Unger S, Pascual-Reguant A, Klocperk A, Seidl M, Marques OC, Eckert M, Gräwe K, Shabani M, von Spee-Mayer C, Friedmann D, Harder I, Gutenberger S, Keller B, Proietti M, Bulashevska A, Grimbacher B, Provaznik J, Benes V, Goldacker S, Schell C, Hauser AE, Boerries M, Hasselblatt P, Warnatz K.  J Clin Immunol. 2022 Oct 25. doi: 10.1007/s10875-022-01379-2. Epub ahead of print.
  69. A Unique Role of the Human Cytomegalovirus Small Capsid Protein in Capsid Assembly. Borst EM, Harmening S, Sanders S, Caragliano E, Wagner K, Lenac Roviš T, Jonjić S, Bosse JB, Messerle M.  mBio. 2022 Oct 26;13(5):e0100722. doi: 10.1128/mbio.01007-22. Epub 2022 Sep 6.
  70. Specific IgE against the house dust mite allergens Der p 5, 20 and 21 influences the phenotype and severity of atopic diseases. Walsemann T, Böttger M, Traidl S, Schwager C, Gülsen A, Freimooser S, Roesner LM, Werfel T, Jappe U. Allergy. 2022 Oct 14.
  71. Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4+ T-cells of Atopic Subjects. Alhamdan F, Laubhahn K, Happle C, Habener A, Jirmo AC, Thölken C, Conca R, Chung HR, Hansen G, Potaczek DP, Schaub B, Grychtol R, Garn H.  Cells. 2022 Sep 22;11(19):2958.
  72. Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes. Ataide MA, Knöpper K, Cruz de Casas P, Ugur M, Eickhoff S, Zou M, Shaikh H, Trivedi A, Grafen A, Yang T, Prinz I, Ohlsen K, Gomez de Agüero M, Beilhack A, Huehn J, Gaya M, Saliba AE, Gasteiger G, Kastenmüller W. Immunity. 2022 Oct 11;55(10):1813-1828.e9. Epub 2022 Aug 23.
  73. Pleural CD14+ monocytes/macrophages of healthy adolescents show a high expression of metallothionein family genes. Schukfeh N, Liu B, DeLuca DS, Tumpara S, Nikolin C, Immenschuh S, Ure BM, Kuebler JF, Welte T, Viemann D, Wallmark SMJ, Vieten G. Eur J Immunol. 2022 Nov 2. Epub ahead of print.
  74. IgA+ memory B-cells are significantly increased in patients with asthma and small airway dysfunction. Habener A, Grychtol R, Gaedcke S, DeLuca D, Dittrich AM, Happle C, Abdo M, Watz H, Pedersen F, König IR, Thiele D, Kopp MV, von Mutius E, Bahmer T, Rabe KF, Meyer-Bahlburg A, Hansen G; ALLIANCE Study Group as part of the German Center for Lung Research (DZL), Fuchs O, Roesler B, Welchering N, Kohistani-Greif N, Kurz J, Landgraf-Rauf K, Laubhahn K, Maison N, Liebl C, Schaub B, Ege M, Illi S, Hose A, Zeitlmann E, Berbig M, Marzi C, Schauberger C, Zissler U, Schmidt-Weber C, Ricklefs I, Diekmann G, Liboschik L, Voigt G, Sultansei L, Weckmann M, Nissen G, Kirsten AM, Waschki B, Herzmann C, Biller H, Gaede KI, Bovermann X, Steinmetz A, Husstedt BL, Nitsche C, Veith V, Szewczyk M, Brinkmann F, Malik A, Schwerk N, Dopfer C, Price M, Jirmo AC, Liu B, Calveron MR, Weber S, Foth S, Skevaki C, Renz H, Meyer M, Schildberg T, Rietschel E, van Koningsbruggen-Rietschel S, Alcazar M. Eur Respir J. 2022 Nov 3;60(5):2102130.
  75. Respiratory Syncytial Virus Two-Step Infection Screen Reveals Inhibitors of Early and Late Life Cycle Stages. Sake SM, Kosch C, Blockus S, Haid S, Gunesch AP, Zhang X, Friesland M, Trummer SB, Grethe C, Kühnel A, Rückert J, Duprex WP, Huang J, Rameix-Welti MA, Empting M, Fischer N, Hirsch AKH, Schulz TF, Pietschmann T. Antimicrob Agents Chemother. 2022 Nov 8:e0103222. doi: 10.1128/aac.01032-22. Epub ahead of print.
  76. Distinct immunological and molecular signatures underpinning influenza vaccine responsiveness in the elderly. Riese P, Trittel S, Akmatov MK, May M, Prokein J, Illig T, Schindler C, Sawitzki B, Elfaki Y, Floess S, Huehn J, Błażejewski AJ, Strowig T, Hernandez-Vargas EA, Geffers R, Zhang B, Li Y, Pessler F, Guzmán CA. Nat Commun. 2022 Nov 12;13(1):6894.
  77. Signs of immunosenescence correlate with poor outcome of mRNA COVID-19 vaccination in older adults. Palacios-Pedrero, M.Á., Jansen, J.M., Blume, C. et al. Nat Aging 2, 896–905 (2022).
  78. Distinct Long- and Short-Term Adaptive Mechanisms in Pseudomonas aeruginosa. Koska M, Kordes A, Erdmann J, Willger SD, Thöming JG, Bähre H, Häussler S. Microbiol Spectr. 2022 Dec 21;10(6):e0304322. Epub 2022 Nov 14.
  79. Assessment of the Gut Microbiota during Juice Fasting with and without Inulin Supplementation: A Feasibility Study in Healthy Volunteers. Thriene, K.; Stanislas, V.; Amend, L.; Strowig, T.; Michels, K.B. Foods 2022, 11, 3673.
  80. Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34+ stromal cell subsets. Pezoldt J, Wiechers C, Zou M, Litovchenko M, Biocanin M, Beckstette M, Sitnik K, Palatella M, van Mierlo G, Chen W, Gardeux V, Floess S, Ebel M, Russeil J, Arampatzi P, Vafardanejad E, Saliba AE, Deplancke B, Huehn J. Nat Commun. 2022 Nov 24;13(1):7227.
  81. In vitro systems to study inborn errors of immunity using human induced pluripotent stem cells. Nikolouli Eirini, Reichstein Janne, Hansen Gesine, Lachmann Nico, Frontiers in Immunology 13, 2022.
  82. Tralokinumab treatment improves the skin microbiota by increasing the microbial diversity in adults with moderate-to-severe atopic dermatitis: Analysis of microbial diversity in ECZTRA 1, a randomized controlled trial. Beck LA, Bieber T, Weidinger S, Tauber M, Saeki H, Irvine AD, Eichenfield LF, Werfel T, Arlert P, Jiang L, Røpke M, Paller AS.  J Am Acad Dermatol. 2022 Dec 5
  83. Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19. Zhang B, Zhang Z, Koeken VACM, Kumar S, Aillaud M, Tsay HC, Liu Z, Kraft ARM, Soon CF, Odak I, Bošnjak B, Vlot A; Deutsche COVID-19 OMICS Initiative (DeCOI); Swertz MA, Ohler U, Geffers R, Illig T, Huehn J, Saliba AE, Sander LE, Förster R, Xu CJ, Cornberg M, Schulte LN, Li Y.  Cell Genom. 2022 Dec 2
  84. An Equine Model for Vaccination against a Hepacivirus: Insights into Host Responses to E2 Recombinant Protein Vaccination and Subsequent Equine Hepacivirus Inoculation. Badenhorst M, Saalmüller A, Daly JM, Ertl R, Stadler M, Puff C, de le Roi M, Baumgärtner W, Engelmann M, Brandner S, Junge HK, Pratscher B, Volz A, Saunier B, Krey T, Wittmann J, Heelemann S, Delarocque J, Wagner B, Todt D, Steinmann E, Cavalleri JV. Viruses. 2022 Jun 27;14(7):1401.
  85. Binding of Glycans to the SARS CoV-2 Spike Protein, an Open Question: NMR Data on Binding Site Localization, Affinity, and Selectivity. Maass T, Ssebyatika G, Brückner M, Breckwoldt L, Krey T, Mallagaray A, Peters T, Frank M, Creutznacher R. Chemistry. 2022 Dec 20;28(71):e202202614.Epub 2022 Oct 26.
  86. Primary antibody deficiency-associated arthritis shares features with spondyloarthritis and enteropathic arthritis. Pott NM, Atschekzei F, Pott CC, Ernst D, Witte T, Sogkas G. RMD Open. 2022 Dec
  87. Fibroblastic reticular cells mitigate acute GvHD via MHCII-dependent maintenance of regulatory T cells. Shaikh H, Pezoldt J, Mokhtari Z, Gamboa Vargas J, Le DD, Peña Mosca J, Arellano Viera E, Kern MA, Graf C, Beyersdorf N, Lutz MB, Riedel A, Büttner-Herold M, Zernecke A, Einsele H, Saliba AE, Ludewig B, Huehn J, Beilhack A. JCI Insight. 2022 Nov 22
  88. Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus Inhibitors. Haack PA, Harmrolfs K, Bader CD, Garcia R, Gunesch AP, Haid S, Popoff A, Voltz A, Kim H, Bartenschlager R, Pietschmann T, Müller R. Angew Chem Int Ed Engl. 2022 Dec 23; Epub 2022 Nov 28.
  89. Genomic epidemiology of clinical ESBL-producing Enterobacteriaceae in a German hospital suggests infections are primarily community- and regionally-acquired. Neffe L, Forde TL, Oravcova K, Köhler U, Bautsch W, Tomasch J, Häussler S.  Microb Genom. 2022 Dec;8(12):mgen000901.
  90. Phenotypic spectrum in recessive STING-associated vasculopathy with onset in infancy: Four novel cases and analysis of previously reported cases. Wan R, Fänder J, Zakaraia I, Lee-Kirsch MA, Wolf C, Lucas N, Olfe LI, Hendrich C, Jonigk D, Holzinger D, Steindor M, Schmidt G, Davenport C, Klemann C, Schwerk N, Griese M, Schlegelberger B, Stehling F, Happle C, Auber B, Steinemann D, Wetzke M, von Hardenberg S. Front Immunol. 2022 Oct 6;13:1029423.
  91. Copy Number Analysis in a Large Cohort Suggestive of Inborn Errors of Immunity Indicates a Wide Spectrum of Relevant Chromosomal Losses and Gains. Wan R, Schieck M, Caballero-Oteyza A, Hofmann W, Cochino AV, Shcherbina A, Sherkat R, Wache-Mainier C, Fernandez A, Sultan M, Illig T, Grimbacher B, Proietti M, Steinemann D. J Clin Immunol. 2022 Jul;42(5):1083-1092.
  92. Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency? Krausz M, Mitsuiki N, Falcone V, Komp J, Posadas-Cantera S, Lorenz HM, Litzman J, Wolff D, Kanariou M, Heinkele A, Speckmann C, Häcker G, Hengel H, Gámez-Díaz L, Grimbacher B. Front Immunol. 2022 Nov 2;13:1011646.
  93. Allele-Specific Disruption of a Common STAT3 Autosomal Dominant Allele Is Not Sufficient to Restore Downstream Signaling in Patient-Derived T Cells. König S, Fliegauf M, Rhiel M, Grimbacher B, Cornu TI, Cathomen T, Mussolino C. Genes (Basel). 2022 Oct 20;13(10):1912.
  94. Birch pollen extract enhances human cytomegalovirus replication in monocyte-derived dendritic cells. Allergy. 2023 Feb;78(2):543-546. Fneish Z, Becker J, Mulenge F, Costa B, Krajewski L, Duran V, Ziegler A, Sommer V, Traidl-Hoffmann C, Gilles S, Kalinke U. doi: 10.1111/all.15497. Epub 2022 Sep 13. PMID: 36038150.
  95. COVID-19 in pediatric lung transplant recipients: Clinical course and outcome. J Heart Lung Transplant. Schütz K, Davids J, Petrik B, Zychlinsky Scharff A, Carlens J, Heim A, Salman J, Ius F, Bobylev D, Hansen G, Müller C, Schwerk N.  2023 Apr;42(4):533-538. doi: 10.1016/j.healun.2022.11.006. Epub 2022 Dec 5. PMID: 36526496; PMCID: PMC9719846.
  96. A circular RNA derived from the insulin receptor locus protects against doxorubicin-induced cardiotoxicity. Lu D, Chatterjee S, Xiao K, Riedel I, Huang CK, Costa A, Cushman S, Neufeldt D, Rode L, Schmidt A, Juchem M, Leonardy J, Büchler G, Blume J, Gern OL, Kalinke U, Wen Tan WL, Foo R, Vink A, van Laake LW, van der Meer P, Bär C, Thum T.  Eur Heart J. 2022 Nov 7;43(42):4496-4511. doi: 10.1093/eurheartj/ehac337. PMID: 35758064; PMCID: PMC9637424.
  97. A CMV-induced adaptive human Vδ1+ γδ T cell clone recognizes HLA-DR. Deseke M, Rampoldi F, Sandrock I, Borst E, Böning H, Ssebyatika GL, Jürgens C, Plückebaum N, Beck M, Hassan A, Tan L, Demera A, Janssen A, Steinberger P, Koenecke C, Viejo-Borbolla A, Messerle M, Krey T, Prinz I. J Exp Med. 2022 Sep 5;219(9):e20212525. doi: 10.1084/jem.20212525. Epub 2022 Jul 19. PMID: 35852466; PMCID: PMC9301659.
  98. Antibacterial and Cytocompatible: Combining Silver Nitrate with Strontium Acetate Increases the Therapeutic Window. Parizi MK, Doll K, Rahim MI, Mikolai C, Winkel A, Stiesch M.  Int J Mol Sci. 2022 Jul 22;23(15):8058. doi: 10.3390/ijms23158058. PMID: 35897634; PMCID: PMC9331456.
  99. Association of SARS-CoV-2 Seropositivity With Myalgic Encephalomyelitis and/or Chronic Fatigue Syndrome Among Children and Adolescents in Germany. Sorg AL, Becht S, Jank M, Armann J, von Both U, Hufnagel M, Lander F, Liese JG, Niehues T, Verjans E, Wetzke M, Stojanov S, Behrends U, Drosten C, Schroten H, von Kries R.  JAMA Netw Open. 2022 Sep 1;5(9):e2233454. doi: 10.1001/jamanetworkopen.2022.33454. PMID: 36166227; PMCID: PMC9516317.
  100. Bacterial low-abundant taxa are key determinants of a healthy airway metagenome in the early years of human life. Pust MM, Tümmler B.  Comput Struct Biotechnol J. 2021 Dec 15;20:175-186. doi: 10.1016/j.csbj.2021.12.008. PMID: 35024091; PMCID: PMC8713036.
  101. Bulevirtide with or without pegIFNα for patients with compensated chronic hepatitis delta: From clinical trials to real-world studies. Lampertico P, Roulot D, Wedemeyer H. J Hepatol. 2022 Nov;77(5):1422-1430. doi: 10.1016/j.jhep.2022.06.010. Epub 2022 Jun 22. PMID: 35752223.
  102. Confirmation of Hyperimmunoglobulin E Syndrome in Two Patients with an Ocular Problem: Detection of Two New DOCK8 Mutations. Saghafi S, Zandieh F, Fazlollahi MR, Glocker C, Frede N, Buchta M, Yang L, Mahmoudi AH, Houshmand M, Pourpak Z, Grimbacher B, Moin M.  Iran J Allergy Asthma Immunol. 2022 Jun 18;21(3):355-363. doi: 10.18502/ijaai.v21i3.9809. PMID: 35822685.
  103. Cross-sectional seroprevalence surveys of SARS-CoV-2 antibodies in children in Germany, June 2020 to May 2021. Sorg AL, Bergfeld L, Jank M, Corman V, Semmler I, Goertz A, Beyerlein A, Verjans E, Wagner N, Von Bernuth H, Lander F, Weil K, Hufnagel M, Spiekerkoetter U, Chao CM, Naehrlich L, Muntau AC, Schulze-Sturm U, Hansen G, Wetzke M, Jung AM, Niehues T, Fricke-Otto S, Von Both U, Huebner J, Behrends U, Liese JG, Schwerk C, Drosten C, Von Kries R, Schroten H.  Nat Commun. 2022 Jun 6;13(1):3128. doi: 10.1038/s41467-022-30482-6. PMID: 35668073; PMCID: PMC9170697.
  104. Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50. Fliegauf M, Kinnunen M, Posadas-Cantera S, Camacho-Ordonez N, Abolhassani H, Alsina L, Atschekzei F, Bogaert DJ, Burns SO, Church JA, Dückers G, Freeman AF, Hammarström L, Hanitsch LG, Kerre T, Kobbe R, Sharapova SO, Siepermann K, Speckmann C, Steiner S, Verma N, Walter JE, Westermann-Clark E, Goldacker S, Warnatz K, Varjosalo M, Grimbacher B.  Front Immunol. 2022 Aug 29;13:965326. doi: 10.3389/fimmu.2022.965326. PMID: 36105815; PMCID: PMC9465457.
  105. Entwicklungsansätze für Impfstoffe gegen Hepatitis-C-Virus-Infektionen [Development approaches for vaccines against hepatitis C virus infections]. Bankwitz D, Krey T, Pietschmann T.  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2022 Feb;65(2):183-191. German. doi: 10.1007/s00103-021-03477-9. Epub 2022 Jan 11. PMID: 35015104; PMCID: PMC8749110.
  106. Distinct actin-tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes. Reindl T, Giese S, Greve JN, Reinke PY, Chizhov I, Latham SL, Mulvihill DP, Taft MH, Manstein DJ. iScience. 2022 May 30;25(7):104484. doi: 10.1016/j.isci.2022.104484. PMID: 35720262; PMCID: PMC9204724.
  107. Effects of Pre-Existing Mental Conditions on Fatigue and Psychological Symptoms Post-COVID-19. Homann S, Mikuteit M, Niewolik J, Behrens GMN, Stölting A, Müller F, Schröder D, Heinemann S, Müllenmeister C, El-Sayed I, Happle C, Steffens S, Dopfer-Jablonka A. Int J Environ Res Public Health. 2022 Aug 11;19(16):9924. doi: 10.3390/ijerph19169924. PMID: 36011559; PMCID: PMC9408008.
  108. Efficacy of dupilumab for the treatment of severe skin disease in cytotoxic T lymphocyte antigen-4 insufficiency: A role of type 2 inflammation? Arruda LK, Cordeiro DL, Langer SS, Koenigham-Santos M, Calado RT, Dias MM, Anhesini LR, Oliveira JB, Grimbacher B, Ferriani MPL.  J Allergy Clin Immunol Glob. 2022 Sep 22;2(1):114-117. doi: 10.1016/j.jacig.2022.08.004. PMID: 37780100; PMCID: PMC10509893.
  109. Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics. Greve JN, Schwäbe FV, Pokrant T, Faix J, Di Donato N, Taft MH, Manstein DJ. Eur J Cell Biol. 2022 Apr;101(2):151216. doi: 10.1016/j.ejcb.2022.151216. Epub 2022 Mar 15. PMID: 35313204.
  110. Generation of Human iPSC from Small Volume Peripheral Blood Samples. Kloos D, Lachmann N. Methods Mol Biol. 2022;2429:27-39. doi: 10.1007/978-1-0716-1979-7_3. PMID: 35507153.
  111. HBcrAg Levels Are Associated With Virological Response to Treatment With Interferon in Patients With Hepatitis Delta. Sandmann L, Yurdaydin C, Deterding K, Heidrich B, Hardtke S, Lehmann P, Bremer B, Manns MP, Cornberg M, Wedemeyer H, Maasoumy B; HIDIT‐II Study Group.  Hepatol Commun. 2022 Mar;6(3):480-495. doi: 10.1002/hep4.1821. Epub 2021 Sep 24. PMID: 34561972; PMCID: PMC8870014.
  112. Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells. Osanyinlusi SA, Zischke J, Jacobs R, Weissinger EM, Schulz TF, Kay-Fedorov PC. HmBio. 2022 Dec 20;13(6):e0294622. doi: 10.1128/mbio.02946-22. Epub 2022 Nov 29. PMID: 36445084; PMCID: PMC9765415.
  113. It’s All in the Mix: A New Interprofessional, Blended-Learning Masters’ Program for Biomedical Data Science Addressing Physicians and Students from Life Sciences – Didactic Concept and First Experiences AuthorsMichael Marschollek, Melina Celik, Marianne Behrends, Thomas Friedrich SchulzPages56 – 60DOI10.3233/SHTI220907CategoryResearch Article Series Studies in Health Technology and Informatics Ebook Volume 298: Digital Professionalism in Health and Care: Developing the Workforce, Building the Future
  114. Low Serum Cholinesterase Identifies Patients With Worse Outcome and Increased Mortality After TIPS. Stockhoff L, Muellner-Bucsics T, Markova AA, Schultalbers M, Keimburg SA, Tergast TL, Hinrichs JB, Simon N, Gerbel S, Manns MP, Mandorfer M, Cornberg M, Meyer BC, Wedemeyer H, Reiberger T, Maasoumy B. Hepatol Commun. 2022 Mar;6(3):621-632. doi: 10.1002/hep4.1829. Epub 2021 Sep 28. PMID: 34585537; PMCID: PMC8870033.
  115. Lymph node stromal cells support the maturation of pre-DCs into cDC-like cells via colony-stimulating factor 1. Wiechers C, Pezoldt J, Beckstette M, Berner J, Schraml BU, Huehn J.  Immunology. 2022 Aug;166(4):475-491. doi: 10.1111/imm.13497. Epub 2022 Jun 2. PMID: 35569092.
  116. Metadata harmonization-Standards are the key for a better usage of omics data for integrative microbiome analysis. Cernava T, Rybakova D, Buscot F, Clavel T, McHardy AC, Meyer F, Meyer F, Overmann J, Stecher B, Sessitsch A, Schloter M, Berg G; MicrobiomeSupport Team.  Environ Microbiome. 2022 Jun 24;17(1):33. doi: 10.1186/s40793-022-00425-1. PMID: 35751093; PMCID: PMC9233336.
  117. Multi-omics analysis of naïve B cells of patients harboring the C104R mutation in TACI. Ramirez N, Posadas-Cantera S, Langer N, de Oteyza ACG, Proietti M, Keller B, Zhao F, Gernedl V, Pecoraro M, Eibel H, Warnatz K, Ballestar E, Geiger R, Bossen C, Grimbacher B. Front Immunol. 2022 Aug 16;13:938240. doi: 10.3389/fimmu.2022.938240. PMID: 36072607; PMCID: PMC9443529.
  118. Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells. Koller N, Höllthaler P, Barends M, Döring M, Spahn C, Durán V, Costa B, Becker J, Heilemann M, Kalinke U, Tampé R. Cell Mol Life Sci. 2022 Aug 10;79(9):477. doi: 10.1007/s00018-022-04472-2. PMID: 35947215; PMCID: PMC9365725.
  119. Phenotype, genotype, treatment, and survival outcomes in patients with X-linked inhibitor of apoptosis deficiency. Yang L, Booth C, Speckmann C, Seidel MG, Worth AJJ, Kindle G, Lankester AC, Grimbacher B; ESID Clinical and Registry Working Parties; Gennery AR, Seppanen MRJ, Morris EC, Burns SO.  J Allergy Clin Immunol. 2022 Aug;150(2):456-466. doi: 10.1016/j.jaci.2021.10.037. Epub 2021 Dec 15. PMID: 34920033.
  120. pUL36 Deubiquitinase Activity Augments Both the Initiation and the Progression of Lytic Herpes Simplex Virus Infection in IFN-Primed Cells. Mohnke J, Stark I, Fischer M, Fischer PM, Schlosser A, Grothey A, O’Hare P, Sodeik B, Erhard F, Dölken L, Hennig T.  J Virol. 2022 Nov 23;96(22):e0096322. doi: 10.1128/jvi.00963-22. Epub 2022 Oct 31. PMID: 36314822; PMCID: PMC9683058.
  121. Resolving the polygenic aetiology of a late onset combined immune deficiency caused by NFKB1 haploinsufficiency and modified by PIK3R1 and TNFRSF13B variants. Hargreaves CE, Dhalla F, Patel AM, de Oteyza ACG, Bateman E, Miller J, Anzilotti C, Ayers L, Grimbacher B, Patel SY.  Clin Immunol. 2022 Jan;234:108910. doi: 10.1016/j.clim.2021.108910. Epub 2021 Dec 15. PMID: 34922003.
  122. SARS-CoV-2 Viral Load in the Pulmonary Compartment of Critically Ill COVID-19 Patients Correlates with Viral Serum Load and Fatal Outcomes. Ynga-Durand M, Maaß H, Milošević M, Krstanović F, Pribanić Matešić M, Jonjić S, Protić A, Brizić I, Šustić A, Čičin-Šain L.  Viruses. 2022 Jun 14;14(6):1292. doi: 10.3390/v14061292. PMID: 35746764; PMCID: PMC9228931.
  123. The First 4 Years – Outcome of Children Identified by Newborn Screening for CF in Germany. Schütz K, Kontsendorn J, Janzen N, Fuge J, Grewendorf S, Klemann C, Happle C, Junge S, Rudolf I, Dopfer C, Sedlacek L, Renz D, Hansen G, Dittrich AM. Klin Padiatr. 2022 Sep;234(5):284-292. English. doi: 10.1055/a-1700-5105. Epub 2022 Jan 28. PMID: 35098497.
  124. The Impact of Evolving SARS-CoV-2 Mutations and Variants on COVID-19 Vaccines. McLean G, Kamil J, Lee B, Moore P, Schulz TF, Muik A, Sahin U, Türeci Ö, Pather S. mBio. 2022 Apr 26;13(2):e0297921. doi: 10.1128/mbio.02979-21. Epub 2022 Mar 30. PMID: 35352979; PMCID: PMC9040821.
  125. Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913. Kazmierski J, Elsner C, Döhner K, Xu S, Ducroux A, Pott F, Jansen J, Thorball CW, Zeymer O, Zhou X, Fedorov R, Fellay J, Löffler MW, Weber ANR, Sodeik B, Goffinet C. A  J Immunol. 2022 Aug 1;209(3):535-547. doi: 10.4049/jimmunol.2100685. PMID: 35851540.
  126. The membrane-active polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics and reduces bacterial virulence. Wang G, Brunel JM, Preusse M, Mozaheb N, Willger SD, Larrouy-Maumus G, Baatsen P, Häussler S, Bolla JM, Van Bambeke F. Commun Biol. 2022 Aug 25;5(1):871. doi: 10.1038/s42003-022-03836-5. PMID: 36008485; PMCID: PMC9411590.
  127. NK cell dysfunction in severe COVID-19: TGF-β-induced downregulation of integrin beta-2 restricts NK cell cytotoxicity. Barros-Martins J, Förster R, Bošnjak B.  Signal Transduct Target Ther. 2022 Jan 31;7(1):32. doi: 10.1038/s41392-022-00892-5. PMID: 35102142; PMCID: PMC8801552.
  128. Atopic Eczema: Pathophysiological Findings as the Beginning of a New Era of Therapeutic Options. Traidl S, Werfel T, Traidl-Hoffmann C. Handb Exp Pharmacol. 2022;268:101-115. doi: 10.1007/164_2021_492. PMID: 34236520.
  129. Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection. Schuhenn J, Meister TL, Todt D, Bracht T, Schork K, Billaud JN, Elsner C, Heinen N, Karakoese Z, Haid S, Kumar S, Brunotte L, Eisenacher M, Di Y, Lew J, Falzarano D, Chen J, Yuan Z, Pietschmann T, Wiegmann B, Uebner H, Taube C, Le-Trilling VTK, Trilling M, Krawczyk A, Ludwig S, Sitek B, Steinmann E, Dittmer U, Lavender KJ, Sutter K, Pfaender S.  Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2111600119. doi: 10.1073/pnas.2111600119. PMID: 35131898; PMCID: PMC8872780.
  130. Editorial: Neuronal and Glial Alterations Caused by Viral Infections. Hernáez B, Viejo-Borbolla A, Cabrera JR.  Front Cell Neurosci. 2022 Apr 5;16:883221. doi: 10.3389/fncel.2022.883221. PMID: 35450209; PMCID: PMC9016110.
  131. Interventional Bronchus Occlusion Using Amplatzer Devices – A Promising Treatment Option for Children with Persistent Air Leak. Schütz K, Happel CM, Keil O, Dingemann J, Carlens J, Wetzke M, Müller C, Köditz H, Griese M, Reiter K, Schweiger-Kabesch A, Backendorf A, Scharff A, Bertram H, Schwerk N.  Klin Padiatr. 2022 Sep;234(5):293-300. English. doi: 10.1055/a-1697-5624. Epub 2022 Jan 3. PMID: 34979579.
  132. The Inflammasome Activity of NLRP3 Is Independent of NEK7 in HEK293 Cells Co-Expressing ASC. Machtens DA, Bresch IP, Eberhage J, Reubold TF, Eschenburg S.  Int J Mol Sci. 2022 Sep 7;23(18):10269. doi: 10.3390/ijms231810269. PMID: 36142182; PMCID: PMC9499477.
  133. Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease. Haring E, Andrieux G, Uhl FM, Krausz M, Proietti M, Sauer B, Esser PR, Martin SF, Pfeifer D, Schmitt-Graeff A, Duyster J, Köhler N, Grimbacher B, Boerries M, Aumann K, Zeiser R, Apostolova P.  Haematologica. 2022 Jul 1;107(7):1538-1554. PMID: 34407601; PMCID: PMC9244832.
  134. Copy Number Analysis in a Large Cohort Suggestive of Inborn Errors of Immunity Indicates a Wide Spectrum of Relevant Chromosomal Losses and Gains. Wan R, Schieck M, Caballero-Oteyza A, Hofmann W, Cochino AV, Shcherbina A, Sherkat R, Wache-Mainier C, Fernandez A, Sultan M, Illig T, Grimbacher B, Proietti M, Steinemann D.  J Clin Immunol. 2022 Jul;42(5):1083-1092. Epub 2022 Apr 29.
  135. Clinical, Immunological and Molecular Findings of Patients with Severe Combined Immunodeficiency: Introducing of 7 Novel Mutations in 7 Genes. Z Alizadeh, MR Fazlollahi, M Mazinani, M Badalzadeh, H Heydarlou, …  Genes Immun
  136. Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency-Associated Villous Atrophy and Norovirus Infection. Strohmeier V, Andrieux G, Unger S, Pascual-Reguant A, Klocperk A, Seidl M, Marques OC, Eckert M, Gräwe K, Shabani M, von Spee-Mayer C, Friedmann D, Harder I, Gutenberger S, Keller B, Proietti M, Bulashevska A, Grimbacher B, Provaznik J, Benes V, Goldacker S, Schell C, Hauser AE, Boerries M, Hasselblatt P, Warnatz K.  J Clin Immunol. 2023 Feb;43(2):371-390. Epub 2022 Oct 25.
  137. Identification of variants in genes associated with autoinflammatory disorders in a cohort of patients with psoriatic arthritis F. Atschekzei, N. Dubrowinskaja, M. Anim, T. Thiele, T. Witte and G. Sogkas RMD Open 2022 Vol. 8 Issue 2 Accession Number: 36113963 PMCID: PMC9486391 DOI: 10.1136/rmdopen-2022-002561
  138. Metamizole-Associated Risks in Decompensated Hepatic Cirrhosis B. Schulte, T. L. Tergast, M. Griemsmann, D. Menti, N. Deveci, J. Kahlhöfer, et al. Dtsch Arztebl Int 2022 Vol. 119 Issue 41 Pages 687-693 Accession Number: 35912424 PMCID: PMC9830680 DOI: 10.3238/arztebl.m2022.0280
  139. Dual Effect: High NADH Levels Contribute to Efflux-Mediated Antibiotic Resistance but Drive Lethality Mediated by Reactive Oxygen Species A. Arce-Rodríguez, D. Pankratz, M. Preusse, P. I. Nikel and S. Häussler mBio 2022 Vol. 13 Issue 1 Pages e0243421 DOI: 10.1128/mbio.02434-21
  1. KIR3DS1 directs NK cell-mediated protection against human adenovirus infections. Jung JM, Ching W, Baumdick ME, Hofmann-Sieber H, Bosse JB, Koyro T, Möller KJ, Wegner L, Niehrs A, Russu K, Ohms M, Zhang W, Ehrhardt A, Duisters K, Spierings E, Hölzemer A, Körner C, Jansen SA, Peine S, Königs I, Lütgehetmann M, Perez D, Reinshagen K, Lindemans CA, Altfeld M, Belderbos M, Dobner T, Bunders MJ. Sci Immunol. 2021 Sep 17;6(63):eabe2942. doi: 10.1126/sciimmunol.abe2942. Epub 2021 Sep 17. PMID: 34533978.
  2. Role of the gut microbiota in airway immunity and host defense against respiratory infections. Willers M, Viemann D. Biol Chem. 2021 Oct 4. doi: 10.1515/hsz-2021-0281. Epub ahead of print. PMID: 34599869.
  3. Bowel Histology of CVID Patients Reveals Distinct Patterns of Mucosal Inflammation. van Schewick CM, Lowe DM, Burns SO, Workman S, Symes A, Guzman D, Moreira F, Watkins J, Clark I, Grimbacher B.  J Clin Immunol. 2021 Oct 1. doi: 10.1007/s10875-021-01104-5. Epub ahead of print. PMID: 34599484.
  4. Specific T cells targeting Staphylococcus aureus fibronectin-binding protein 1 induce a type 2/type 1 inflammatory response in sensitized atopic dermatitis patients. Farag AK, Roesner LM, Wieschowski S, Heratizadeh A, Eiz-Vesper B, Kwok WW, Valenta R, Werfel T. Allergy. 2021 Oct 3. doi: 10.1111/all.15120. Epub ahead of print. PMID: 34601735.
  5. Regulatory B cells control airway hyperreactivity and lung remodeling in a murine asthma model. Habener A, Happle C, Grychtol R, Skuljec J, Busse M, Dalüge K, Obernolte H, Sewald K, Braun A, Meyer-Bahlburg A, Hansen G.  J Allergy Clin Immunol. 2021 Jun;147(6):2281-2294.e7. doi: 10.1016/j.jaci.2020.09.041. Epub 2020 Nov 27. PMID: 33249168.
  6. The journey of herpesvirus capsids and genomes to the host cell nucleus. Döhner K, Cornelius A, Serrero MC, Sodeik B. Curr Opin Virol. 2021 Oct;50:147-158. doi: 10.1016/j.coviro.2021.08.005. Epub 2021 Aug 28. PMID: 34464845.
  7. Klebsiella oxytoca causes colonization resistance against multidrug-resistant K. pneumoniae in the gut via cooperative carbohydrate competition. Osbelt L, Wende M, Almási É, Derksen E, Muthukumarasamy U, Lesker TR, Galvez EJC, Pils MC, Schalk E, Chhatwal P, Färber J, Neumann-Schaal M, Fischer T, Schlüter D, Strowig T. Cell Host Microbe. 2021 Sep 29:S1931-3128(21)00419-4. doi: 10.1016/j.chom.2021.09.003. Epub ahead of print. PMID: 34610293.
  8. Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect. Haematologica. Haring E, Uhl FM, Andrieux G, Proietti M, Bulashevska A, Sauer B, Braun LM, de Vega Gomez E, Esser PR, Martin SF, Pfeifer D, Follo M, Schmitt-Graeff A, Buescher J, Duyster J, Grimbacher B, Boerries M, Pearce EL, Zeiser R, Apostolova P. 2021 Aug 1;106(8):2131-2146. doi: 10.3324/haematol.2019.242990. PMID: 32675222; PMCID: PMC8327708.
  9. Diagnostic Yield and Therapeutic Consequences of Targeted Next-Generation Sequencing in Sporadic Primary Immunodeficiency. Sogkas G, Dubrowinskaja N, Schütz K, Steinbrück L, Götting J, Schwerk N, Baumann U, Grimbacher B, Witte T, Schmidt RE, Atschekzei F.  Int Arch Allergy Immunol. 2021 Oct 7:1-13. doi: 10.1159/000519199. Epub ahead of print. PMID: 34619682.
  10. Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination. Hammerschmidt SI, Bosnjak B, Bernhardt G, Friedrichsen M, Ravens I, Dopfer-Jablonka A, Hoffmann M, Pöhlmann S, Behrens GMN, Förster R. Cell Mol Immunol. 2021 Oct;18(10):2455-2456. doi: 10.1038/s41423-021-00755-z. Epub 2021 Aug 23. PMID: 34426672; PMCID: PMC8381713.
  11. Recent Advances in Developing Treatments of Kaposi’s Sarcoma Herpesvirus-Related Diseases. Naimo E, Zischke J, Schulz TF.  Viruses. 2021 Sep 9;13(9):1797. doi: 10.3390/v13091797. PMID: 34578378; PMCID: PMC8473310.
  12. Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2. Zhu S, Stanslowsky N, Fernández-Trillo J, Mamo TM, Yu P, Kalmbach N, Ritter B, Eggenschwiler R, Ouwendijk WJD, Mzinza D, Tan L, Leffler A, Spohn M, Brown RJP, Kropp KA, Kaever V, Ha TC, Narayanan P, Grundhoff A, Förster R, Schambach A, Verjans GMGM, Schmidt M, Kispert A, Cantz T, Gomis A, Wegner F, Viejo-Borbolla A. Stem Cell Res. 2021 Sep 11;56:102535. doi: 10.1016/j.scr.2021.102535. Epub ahead of print. PMID: 34607262.
  13. Pathogenesis and virulence of herpes simplex virus. Zhu S, Viejo-Borbolla A. Virulence. 2021 Dec;12(1):2670-2702. doi: 10.1080/21505594.2021.1982373. PMID: 34676800.
  14. Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells. Formaglio P, Alabdullah M, Siokis A, Handschuh J, Sauerland I, Fu Y, Krone A, Gintschel P, Stettin J, Heyde S, Mohr J, Philipsen L, Schröder A, Robert PA, Zhao G, Khailaie S, Dudeck A, Bertrand J, Späth GF, Kahlfuß S, Bousso P, Schraven B, Huehn J, Binder S, Meyer-Hermann M, Müller AJ. Immunity. 2021 Oct 15:S1074-7613(21)00406-4. doi: 10.1016/j.immuni.2021.09.021. Epub ahead of print. PMID: 34687607.
  15. Toll-like Receptors in Viral Encephalitis. Gern OL, Mulenge F, Pavlou A, Ghita L, Steffen I, Stangel M, Kalinke U.  Viruses. 2021 Oct 14;13(10):2065. doi: 10.3390/v13102065. PMID: 34696494.
  16. Impact of HBsAg and HBcrAg levels on phenotype and function of HBV-specific T cells in patients with chronic hepatitis B virus infection. Aliabadi E, Urbanek-Quaing M, Maasoumy B, Bremer B, Grasshoff M, Li Y, Niehaus CE, Wedemeyer H, Kraft ARM, Cornberg M. Gut. 2021 Oct 26:gutjnl-2021-324646. doi: 10.1136/gutjnl-2021-324646. Epub ahead of print. PMID: 34702717.
  17. Mesenteric Lymph Node Transplantation in Mice to Study Immune Responses of the Gastrointestinal Tract. Haroon Shaikh, Juan Gamboa Vargas, Zeinab Mokhtari, Katja J. Jarick, Maria Ulbrich, Josefina Peña Mosca, Estibaliz Arellano Viera, Caroline Graf, Duc-Dung Le, Katrin G. Heinze, Maike Büttner-Herold, Andreas Rosenwald, Joern Pezoldt, Jochen Huehn, Andreas Beilhack.  Front Immunol. 2021; 12: 689896. Published online 2021 Jul 26.
  18. Concatemeric Broccoli reduces mRNA stability and induces aggregates. Rink MR, Baptista MAP, Flomm FJ, Hennig T, Whisnant AW, Wolf N, Seibel J, Dölken L, Bosse JB. PLoS One. 2021 Aug 4;16(8):e0244166. doi: 10.1371/journal.pone.0244166. eCollection 2021. PMID: 34347781 Free PMC article.
  19. Quo vadis clinical diagnostic microbiology? Haag S, Häussler S. Clin Microbiol Infect. 2021 Jul 26:S1198-743X(21)00404-3. doi: 10.1016/j.cmi.2021.07.013. Online ahead of print. PMID: 34325069 No abstract available.
  20. Tbx21 and Foxp3 Are Epigenetically Stabilized in T-Bet+ Tregs That Transiently Accumulate in Influenza A Virus-Infected Lungs. Elfaki Y, Yang J, Boehme J, Schultz K, Bruder D, Falk CS, Huehn J, Floess S. Int J Mol Sci. 2021 Jul 14;22(14):7522. doi: 10.3390/ijms22147522. PMID: 34299148 Free PMC article.
  21. Sequential MAVS and MyD88/TRIF signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes. Ghita L, Breitkopf V, Mulenge F, Pavlou A, Gern OL, Durán V, Prajeeth CK, Kohls M, Jung K, Stangel M, Steffen I, Kalinke U. J Neurosci Res. 2021 Jul 23. doi: 10.1002/jnr.24923. Online ahead of print. PMID: 34296786
  22. Distribution of major lymphocyte subsets and memory T-cell subpopulations in healthy adults employing GLP-conforming multicolor flow cytometry. Schultze-Florey CR, Chukhno E, Goudeva L, Blasczyk R, Ganser A, Prinz I, Förster R, Koenecke C, Odak I. Leukemia. 2021 Jul 21. doi: 10.1038/s41375-021-01348-5. Online ahead of print. PMID: 34290358 No abstract available.
  23. Deubiquitinating enzymes (DUBs): decipher underlying basis of neurodegenerative diseases. Liu B, Ruan J, Chen M, Li Z, Manjengwa G, Schlüter D, Song W, Wang X. Mol Psychiatry. 2021 Jul 20. doi: 10.1038/s41380-021-01233-8. Online ahead of print. PMID: 34285347 Review.
  24. Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination. Barros-Martins J, Hammerschmidt SI, Cossmann A, Odak I, Stankov MV, Morillas Ramos G, Dopfer-Jablonka A, Heidemann A, Ritter C, Friedrichsen M, Schultze-Florey C, Ravens I, Willenzon S, Bubke A, Ristenpart J, Janssen A, Ssebyatika G, Bernhardt G, Münch J, Hoffmann M, Pöhlmann S, Krey T, Bošnjak B, Förster R, Behrens GMN. Nat Med. 2021 Jul 14. doi: 10.1038/s41591-021-01449-9. Online ahead of print. PMID: 34262158
  25. Expression of ACKR4 demarcates the „peri-marginal sinus,“ a specialized vascular compartment of the splenic red pulp. Werth K, Hub E, Gutjahr JC, Bosjnak B, Zheng X, Bubke A, Russo S, Rot A, Förster R. Cell Rep. 2021 Jul 13;36(2):109346. doi: 10.1016/j.celrep.2021.109346. PMID: 34260918
  26. TACI deficiency – a complex system out of balance. Salzer U, Grimbacher B. Curr Opin Immunol. 2021 Jul 8;71:81-88. doi: 10.1016/j.coi.2021.06.004. Online ahead of print. PMID: 34247095 Review.
  27. A rare case of neuro- and otosyphilis in secondary syphilis. Traidl S, Angela Y, Stender A, Kulberg A, Tronnier M, Prenzler NK, Wattjes MP, Kapp A, Stangel M, Schacht V, Werfel T. J Eur Acad Dermatol Venereol. 2021 Jul 9. doi: 10.1111/jdv.17512. Online ahead of print. PMID: 34242450 No abstract available.
  28. Atopic Eczema: Pathophysiological Findings as the Beginning of a New Era of Therapeutic Options. Traidl S, Werfel T, Traidl-Hoffmann C. Handb Exp Pharmacol. 2021 Jul 9. doi: 10.1007/164_2021_492. Online ahead of print. PMID: 34236520
  29. Transcriptome analysis following neurotropic virus infection reveals faulty innate immunity and delayed antigen presentation in mice susceptible to virus-induced demyelination. Ciurkiewicz M, Floess S, Beckstette M, Kummerfeld M, Baumgärtner W, Huehn J, Beineke A. Brain Pathol. 2021 Jul 6:e13000. doi: 10.1111/bpa.13000. Online ahead of print. PMID: 34231271
  30. Improvement of image resolution by combining enhanced confocal microscopy and quantum dot triexciton imaging. Hennig S, Manstein DJ.
    FEBS Open Bio. 2021 Jul 6. doi: 10.1002/2211-5463.13246. Online ahead of print. PMID: 34228908
  31. Lymph-Derived Neutrophils Primarily Locate to the Subcapsular and Medullary Sinuses in Resting and Inflamed Lymph Nodes. de Castro Pinho J, Förster R. Cells. 2021 Jun 12;10(6):1486. doi: 10.3390/cells10061486. PMID: 34204825 Free PMC article.
  32. Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum. Rai A, Klare JP, Reinke PYA, Englmaier F, Fohrer J, Fedorov R, Taft MH, Chizhov I, Curth U, Plettenburg O, Manstein DJ. Int J Mol Sci. 2021 Jun 10;22(12):6265. doi: 10.3390/ijms22126265. PMID: 34200865 Free PMC article.
  33. Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis. Kopfnagel V, Dreyer S, Zeitvogel J, Pieper DH, Buch A, Sodeik B, Rademacher F, Harder J, Werfel T. Allergy. 2021 Jun 27. doi: 10.1111/all.14992. Online ahead of print. PMID: 34176149
  34. Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses. Yu K, Hammerschmidt SI, Permanyer M, Galla M, Rothe M, Zheng X, Werth K, Martens R, Lueder Y, Janssen A, Friedrichsen M, Bernhardt G, Förster R. Cell Rep. 2021 Jun 22;35(12):109273. doi: 10.1016/j.celrep.2021.109273. PMID: 34161766
  35. There is no gene for CVID – novel monogenetic causes for primary antibody deficiency. Ramirez NJ, Posadas-Cantera S, Caballero-Oteyza A, Camacho-Ordonez N, Grimbacher B. Curr Opin Immunol. 2021 Jun 18;72:176-185. doi: 10.1016/j.coi.2021.05.010. Online ahead of print. PMID: 34153571 Review.
  36. Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation. Samarina N, Ssebyatika G, Tikla T, Waldmann JY, Abere B, Nanna V, Marasco M, Carlomagno T, Krey T, Schulz TF. PLoS Pathog. 2021 Jun 18;17(6):e1009635. doi: 10.1371/journal.ppat.1009635. eCollection 2021 Jun. PMID: 34143834 Free PMC article.
  37. Therapeutic options for CTLA-4 insufficiency. Egg D, Rump IC, Mitsuiki N, Rojas-Restrepo J, Maccari ME, Schwab C, Gabrysch A, Warnatz K, Goldacker S, Patiño V, Wolff D, Okada S, Hayakawa S, Shikama Y, Kanda K, Imai K, Sotomatsu M, Kuwashima M, Kamiya T, Morio T, Matsumoto K, Mori T, Yoshimoto Y, Dybedal I, Kanariou M, Kucuk ZY, Chapdelaine H, Petruzelkova L, Lorenz HM, Sullivan KE, Heimall J, Moutschen M, Litzman J, Recher M, Albert MH, Hauck F, Seneviratne S, Pachlopnik Schmid J, Kolios A, Unglik G, Klemann C, Snapper S, Giulino-Roth L, Svaton M, Platt CD, Hambleton S, Neth O, Gosse G, Reinsch S, Holzinger D, Kim YJ, Bakhtiar S, Atschekzei F, Schmidt R, Sogkas G, Chandrakasan S, Rae W, Derfalvi B, Marquart HV, Ozen A, Kiykim A, Karakoc-Aydiner E, Králíčková P, de Bree G, Kiritsi D, Seidel MG, Kobbe R, Dantzer J, Alsina L, Armangue T, Lougaris V, Agyeman P, Nyström S, Buchbinder D, Arkwright PD, Grimbacher B. J Allergy Clin Immunol. 2021 Jun 7:S0091-6749(21)00891-5. doi: 10.1016/j.jaci.2021.04.039. Online ahead of print. PMID: 34111452
  38. S100A8/A9 is the first predictive marker for neonatal sepsis. Pirr S, Dauter L, Vogl T, Ulas T, Bohnhorst B, Roth J, Viemann D.Clin Transl Med. 2021 Apr;11(4):e338. doi: 10.1002/ctm2.338.PMID: 33931974Free PMC article.No abstract available.
  39. MyD88 signaling by neurons induces chemokines that recruit protective leukocytes to the virus-infected CNS. Ghita L, Spanier J, Chhatbar C, Mulenge F, Pavlou A, Larsen PK, Waltl I, Lueder Y, Kohls M, Jung K, Best SM, Förster R, Stangel M, Schreiner D, Kalinke U. Sci Immunol. 2021 Jun 25;6(60):eabc9165. doi: 10.1126/sciimmunol.abc9165. PMID: 34172587.
  40. Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction. Franz S, Pott F, Zillinger T, Schüler C, Dapa S, Fischer C, Passos V, Stenzel S, Chen F, Döhner K, Hartmann G, Sodeik B, Pessler F, Simmons G, Drexler JF, Goffinet C.  Life Sci Alliance. 2021 Jun 2;4(7):e202000909. doi: 10.26508/lsa.202000909. PMID: 34078739; PMCID: PMC8200292.
  41. Cytomegalovirus subverts macrophage identity. Baasch S, Giansanti P, Kolter J, Riedl A, Forde AJ, Runge S, Zenke S, Elling R, Halenius A, Brabletz S, Hengel H, Kuster B, Brabletz T, Cicin-Sain L, Arens R, Vlachos A, Rohr JC, Stemmler MP, Kopf M, Ruzsics Z, Henneke P. Cell. 2021 Jun 5:S0092-8674(21)00626-7. doi: 10.1016/j.cell.2021.05.009. Online ahead of print. PMID: 34115982
  42. Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections. Al-Mekhlafi A, Sühs KW, Schuchardt S, Kuhn M, Müller-Vahl K, Trebst C, Skripuletz T, Klawonn F, Stangel M, Pessler F.  Cells. 2021 May 6;10(5):1115. doi: 10.3390/cells10051115. PMID: 34066349; PMCID: PMC8148106.
  43. Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega-7,9 trans-fat rumenic acid. Irene Pertici, Manuel H. Taft, Johannes N. Greve, Roman Fedorov, Marco Caremani, Dietmar J. Manstein. Journal of Physiology. First published: 04 May 2021
  44. A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood. Likai Tan, Alina Suzann Fichtner, Elena Bruni, Ivan Odak, Inga Sandrock, Anja Bubke, Alina Borchers, Christian Schultze-Florey, Christian Koenecke, Reinhold Förster, Michael Jarek, Constantin von Kaisenberg, Ansgar Schulz, Xiaojing Chu, Bowen Zhang, Yang Li, Ulf Panzer, Christian F. Krebs, Sarina Ravens, Immo Prinz. Science Immunology 23 Apr 2021
  45. Extracellular vesicles in neuroinflammation: Pathogenesis, diagnosis, and therapy. Ruan J, Miao X, Schlüter D, Lin L, Wang X. Mol Ther. 2021 Jun 2;29(6):1946-1957. doi: 10.1016/j.ymthe.2021.04.020. Epub 2021 Apr 23. PMID: 33895328 Review.
  46. Ovarian tumor domain proteases in pathogen infection. Review. Trends in Microbiology. Dirk Schlüter, EricSchulze-Niemand, Matthias Stein, Michael Naumann, online 17 May 2021 https://doi.org/10.1016/j.tim.2021.04.002
  47. Aging and options to halt declining immunity to virus infections. Miguel Ángel Palacios-Pedrero, Albert D.M.E. Osterhaus, Tanja Becker, Husni Elbahesh, Guus F. Rimmelzwaan and Giulietta Saletti. Front. Immunol., 12 May 2021 | https://doi.org/10.3389/fimmu.2021.681449
  48. Eczema herpeticum in atopic dermatitis. Traidl S, Rösner L, Zeitvogel J, Werfel T. Allergy. 2021 Apr 12. doi: 10.1111/all.14853. Online ahead of print. PMID: 33844308 Review.
  49. Tim-3 is dispensable for allergic inflammation and respiratory tolerance in experimental asthma. Boehne C, Behrendt AK, Meyer-Bahlburg A, Boettcher M, Drube S, Kamradt T, Hansen G. PLoS One. 2021 Apr 6;16(4):e0249605. doi: 10.1371/journal.pone.0249605. eCollection 2021.
    PMID: 33822811
  50. Reverse genetics systems for contemporary isolates of respiratory syncytial virus enable rapid evaluation of antibody escape mutants. Jo WK, Schadenhofer A, Habierski A, Kaiser FK, Saletti G, Ganzenmueller T, Hage E, Haid S, Pietschmann T, Hansen G, Schulz TF, Rimmelzwaan GF, Osterhaus ADME, Ludlow M. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2026558118. doi: 10.1073/pnas.2026558118.
    PMID: 33811145
  51. Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells. Pae J, Ersching J, Castro TBR, Schips M, Mesin L, Allon SJ, Ordovas-Montanes J, Mlynarczyk C, Melnick A, Efeyan A, Shalek AK, Meyer-Hermann M, Victora GD. J Exp Med. 2021 Apr 5;218(4):e20201699. doi: 10.1084/jem.20201699. PMID: 33332554
  52. Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity. Sogkas G, Atschekzei F, Adriawan IR, Dubrowinskaja N, Witte T, Schmidt RE. Cell Mol Immunol. 2021 Apr 1:1-19. doi: 10.1038/s41423-020-00626-z. Online ahead of print. PMID: 33795850 Free PMC article. Review.
  53. Removable denture is a risk indicator for peri-implantitis and facilitates expansion of specific periodontopathogens: a cross-sectional study. Grischke J, Szafrański SP, Muthukumarasamy U, Haeussler S, Stiesch M. BMC Oral Health. 2021 Apr 1;21(1):173. doi: 10.1186/s12903-021-01529-9. PMID: 33794847 Free PMC article.
  54. The impact of hepatitis B surface antigen on natural killer cells in patients with chronic hepatitis B infection.
    Du Y, Anastasiou OE, Strunz B, Scheuten J, Bremer B, Kraft A, Kleinsimglinhaus K, Todt D, Broering R, Hardtke-Wolenski M, Wu J, Yang D, Dittmer U, Lu M, Cornberg M, Björkström NK, Khera T, Wedemeyer H. Liver Int. 2021 Apr 1. doi: 10.1111/liv.14885. Online ahead of print. PMID: 33794040
  55. Beyond „Big Eaters“: The Versatile Role of Alveolar Macrophages in Health and Disease. Hetzel M, Ackermann M, Lachmann N. Int J Mol Sci. 2021 Mar 24;22(7):3308. doi: 10.3390/ijms22073308. PMID: 33804918 Free PMC article. Review.
  56. The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes. Wiechers C, Zou M, Galvez E, Beckstette M, Ebel M, Strowig T, Huehn J, Pezoldt J. Cell Mol Immunol. 2021 Mar 24. doi: 10.1038/s41423-021-00647-2. Online ahead of print. PMID: 33762684
  57. OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation. Koschel J, Nishanth G, Just S, Harit K, Kröger A, Deckert M, Naumann M, Schlüter D. Cell Death Differ. 2021 Mar 12. doi: 10.1038/s41418-021-00752-9. Online ahead of print. PMID: 33712742
  58. Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T-cell development in mice. Elfaki Y, Robert PA, Binz C, Falk CS, Bruder D, Prinz I, Floess S, Meyer-Hermann M, Huehn J. Eur J Immunol. 2021 Feb 26. doi: 10.1002/eji.202048981. Online ahead of print. PMID: 33638148
  59. Lymph node stromal cell subsets-Emerging specialists for tailored tissue-specific immune responses. Zou M, Wiechers C, Huehn J. Int J Med Microbiol. 2021 Apr;311(3):151492. doi: 10.1016/j.ijmm.2021.151492. Epub 2021 Feb 25. PMID: 33676241
  60. Development of the reproduction number from coronavirus SARS-CoV-2 case data in Germany and implications for political measures. Khailaie S, Mitra T, Bandyopadhyay A, Schips M, Mascheroni P, Vanella P, Lange B, Binder SC, Meyer-Hermann M. BMC Med. 2021 Jan 28;19(1):32. doi: 10.1186/s12916-020-01884-4. PMID: 33504336 Free PMC article.
  61. 3D culture conditions support Kaposi’s sarcoma herpesvirus (KSHV) maintenance and viral spread in endothelial cells. Dubich T, Dittrich A, Bousset K, Geffers R, Büsche G, Köster M, Hauser H, Schulz TF, Wirth D. J Mol Med (Berl). 2021 Mar;99(3):425-438. doi: 10.1007/s00109-020-02020-8. Epub 2021 Jan 23. PMID: 33484281 Free PMC article.
  62. A Novel Triple-Fluorescent HCMV Strain Reveals Gene Expression Dynamics and Anti-Herpesviral Drug Mechanisms. Rand U, Kubsch T, Kasmapour B, Cicin-Sain L. Front Cell Infect Microbiol. 2021 Jan 8;10:536150. doi: 10.3389/fcimb.2020.536150. eCollection 2020. PMID: 33489928 Free PMC article.
  63. Efficient IL-2R signaling differentially affects the stability, function, and composition of the regulatory T-cell pool. Permanyer M, Bošnjak B, Glage S, Friedrichsen M, Floess S, Huehn J, Patzer GE, Odak I, Eckert N, Zargari R, Ospina-Quintero L, Georgiev H, Förster R. Cell Mol Immunol. 2021 Feb;18(2):398-414. doi: 10.1038/s41423-020-00599-z. Epub 2021 Jan 6. PMID: 33408345
  64. Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum. Rai A, Klare JP, Reinke PYA, Englmaier F, Fohrer J, Fedorov R, Taft MH, Chizhov I, Curth U, Plettenburg O, Manstein DJ. Int J Mol Sci. 2021 Jun 10;22(12):6265.
  65. Development of an in vitro assay for the detection of polymerization of the pyrin domain of ASC. Bresch IP, Machtens DA, Reubold TF, Eschenburg S. Biotechniques. 2021 Jun;70(6):350-354.
  66. Interdependent Impact of Lipoprotein Receptors and Lipid-Lowering Drugs on HCV Infectivity. Zapatero-Belinchón, F.J.; Ötjengerdes, R.; Sheldon, J.; Schulte, B.; Carriquí-Madroñal, B.; Brogden, G.; Arroyo-Fernández, L.M.; Vondran, F.W.R.; Maasoumy, B.; von Hahn, T.; Gerold, G. Cells 2021, 10, 1626.
  67. Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination. Tscherne A, Schwarz JH, Rohde C, Kupke A, Kalodimou G, Limpinsel L, Okba NMA, Bošnjak B, Sandrock I, Odak I, Halwe S, Sauerhering L, Brosinski K, Liangliang N, Duell E, Jany S, Freudenstein A, Schmidt J, Werner A, Gellhorn Serra M, Klüver M, Guggemos W, Seilmaier M, Wendtner CM, Förster R, Haagmans BL, Becker S, Sutter G, Volz A. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2026207118.
  68. Case Report: Convalescent Plasma Therapy Induced Anti-SARS-CoV-2 T Cell Expansion, NK Cell Maturation and Virus Clearance in a B Cell Deficient Patient After CD19 CAR T Cell Therapy. Bošnjak B, Odak I, Ritter C, Stahl K, Graalmann T, Steinbrück L, Blasczyk R, Falk CS, Schulz TF, Wedemeyer HH, Cornberg M, Ganser A, Förster R, Koenecke C. Front Immunol. 2021 Aug 12;12:721738
  69. A molecular theory of germinal center B cell selection and division. Meyer-Hermann M. Cell Rep. 2021 Aug 24;36(8):109552.
  70. CHildhood Allergy and tolerance: Biomarkers and Predictors (CHAMP) and quality of life. Eckert JK, Kahle J, Böck A, Zeber K, Urner K, Greiner W, Kreimeier S, Beyer K, Dobbertin-Welsch J, Hamelmann E, Gellhaus I, Schorlemer C, Kabesch M, Kheiroddin P, von Mutius E, Depner M, Walter D, Hansen G, DeStefano S, Schnadt S, Schaub B; CHAMP Consortium. Pediatr Allergy Immunol. 2021 Aug 16.
  71. Ymir: A 3D structural affinity model for multi-epitope vaccine simulations. Robert PA, Arulraj T, Meyer-Hermann M. iScience. 2021 Aug 14;24(9):102979.
  72. Assembly of infectious Kaposi’s sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer. Naniima P, Naimo E, Koch S, Curth U, Alkharsah KR, Ströh LJ, Binz A, Beneke JM, Vollmer B, Böning H, Borst EM, Desai P, Bohne J, Messerle M, Bauerfeind R, Legrand P, Sodeik B, Schulz TF, Krey T. PLoS Biol. 2021 Nov 4;19(11):e3001423.
  73. Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents. Bošnjak B, Odak I, Barros-Martins J, Sandrock I, Hammerschmidt SI, Permanyer M, Patzer GE, Greorgiev H, Gutierrez Jauregui R, Tscherne A, Schwarz JH, Kalodimou G, Ssebyatika G, Ciurkiewicz M, Willenzon S, Bubke A, Ristenpart J, Ritter C, Tuchel T, Meyer Zu Natrup C, Shin DL, Clever S, Limpinsel L, Baumgärtner W, Krey T, Volz A, Sutter G, Förster R. Front Immunol. 2021 Nov 11;12:772240.
  74. Conserved E1B-55K SUMOylation in different human adenovirus species is a potent regulator of intracellular localization. Kolbe V, Ip WH, Kieweg-Thompson L, Lang J, Gruhne J, Meyer T, Wilkens B, Schie M, Thünauer R, Schreiner S, Bertzbach LD, Rodríguez E, Dobner T. J Virol. 2021 Nov 17:JVI0083821.
  75. Human Adenovirus Type 5 Infection Leads to Nuclear Envelope Destabilization and Membrane Permeability Independently of Adenovirus Death Protein. Pfitzner S, Bosse JB, Hofmann-Sieber H, Flomm F, Reimer R, Dobner T, Grünewald K, Franken LE. HInt J Mol Sci. 2021 Dec 2;22(23):13034.
  76. Imaging dendritic cell functions. Bošnjak B, Do KTH, Förster R, Hammerschmidt SI. Immunol Rev. 2021 Dec 3.
  77. Robust induction of neutralizing antibodies against the SARS-CoV-2 Delta variant after homologous Spikevax or heterologous Vaxzevria-Spikevax vaccination. Hammerschmidt SI, Thurm C, Bošnjak B, Bernhardt G, Reinhold A, Willenzon S, Ritter C, Reinhold D, Schraven B, Förster R. Eur J Immunol. 2021 Dec 6.
  78. Long-Lasting Immunity Against SARS-CoV-2: Dream or Reality? Gussarow D, Bonifacius A, Cossmann A, Stankov MV, Mausberg P, Tischer-Zimmermann S, Gödecke N, Kalinke U, Behrens GMN, Blasczyk R, Eiz-Vesper B. Front Med (Lausanne). 2021 Nov 25;8:770381.
  79. Beneficial and detrimental functions of microglia during viral encephalitis. Waltl I, Kalinke U.  Trends Neurosci. 2021 Dec 11:S0166-2236(21)00233-2.
  80. Human iPSC-derived macrophages for efficient Staphylococcus aureus clearance in a murine pulmonary infection model. Rafiei Hashtchin A, Fehlhaber B, Hetzel M, Manstein F, Stalp JL, Glage S, Abeln M, Zweigerdt R, Munder A, Viemann D, Ackermann M, Lachmann N. Blood Adv. 2021 Dec 14;5(23):5190-5201.
  81. Infection-induced chromatin modifications facilitate translocation of herpes simplex virus capsids to the inner nuclear membrane. Aho V, Salminen S, Mattola S, Gupta A, Flomm F, Sodeik B, Bosse JB, Vihinen-Ranta M.PLoS Pathog. 2021 Dec 15;17(12):e1010132.
  82. Perception of the coronavirus pandemic by patients with atopic dermatitis – Results from the TREATgermany registry. Helmert C, Siegels D, Haufe E, Abraham S, Heratizadeh A, Kleinheinz A, Harder I, Schäkel K, Effendy I, Wollenberg A, Sticherling M, Stahl M, Worm M, Schwichtenberg U, Schwarz B, Rossbacher J, Buck PM, Schenck F, Werfel T, Weidinger S, Schmitt J; TREATgermany Study Team. J Dtsch Dermatol Ges. 2021 Dec 27.
  83. Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization. Weber T, Potthoff J, Bizu S, Labuhn M, Dold L, Schoofs T, Horning M, Ercanoglu MS, Kreer C, Gieselmann L, Vanshylla K, Langhans B, Janicki H, Ströh LJ, Knops E, Nierhoff D, Spengler U, Kaiser R, Bjorkman PJ, Krey T, Bankwitz D, Pfeifer N, Pietschmann T, Flyak AI, Klein F. Immunity. 2021 Dec 29:S1074-7613(21)00536-7.
  84. Multiple Immunostainings with Different Epitope Retrievals-The FOLGAS Protocol. von Schoenfeld A, Bronsert P, Poc M, Fuller A, Filby A, Kraft S, Kurowski K, Sörensen K, Huber J, Pfeiffer J, Proietti M, Stehl V, Werner M, Seidl M. Int J Mol Sci. 2021 Dec 25;23(1):223.
  85. Establishing the Molecular Diagnoses in a Cohort of 291 Patients With Predominantly Antibody Deficiency by Targeted Next-Generation Sequencing: Experience From a Monocentric Study. Rojas-Restrepo J, Caballero-Oteyza A, Huebscher K, Haberstroh H, Fliegauf M, Keller B, Kobbe R, Warnatz K, Ehl S, Proietti M *, Grimbacher B *. Front Immunol. 2021 Dec 17;12:786516.
  86. Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease. Haring E, Andrieux G, Uhl FM, Krausz M, Proietti M, Sauer B, Esser PR, Martin SF, Pfeifer D, Schmitt-Graeff A, Duyster J, Köhler N, Grimbacher B, Boerries M, Aumann K, Zeiser R, Apostolova P. Haematologica. 2021 Aug 19.
  87. Genetic Analysis of a Cohort of 275 Patients with Hyper-IgE Syndromes and/or Chronic Mucocutaneous Candidiasis. Frede N, Rojas-Restrepo J, Caballero Garcia de Oteyza A, Buchta M, Hübscher K, Gámez-Díaz L, Proietti M, Saghafi S, Chavoshzadeh Z, Soler-Palacin P, Galal N, Adeli M, Aldave-Becerra JC, Al-Ddafari MS, Ardenyz Ö, Atkinson TP, Kut FB, Çelmeli F, Rees H, Kilic SS, Kirovski I, Klein C, Kobbe R, Korganow AS, Lilic D, Lunt P, Makwana N, Metin A, Özgür TT, Karakas AA, Seneviratne S, Sherkat R, Sousa AB, Unal E, Patiroglu T, Wahn V, von Bernuth H, Whiteford M, Doffinger R, Jouhadi Z, Grimbacher B. J Clin Immunol. 2021 Nov;41(8):1804-1838.
  88. Altered Spectrum of Lymphoid Neoplasms in a Single-Center Cohort of Common Variable Immunodeficiency with Immune Dysregulation. Wehr C, Houet L, Unger S, Kindle G, Goldacker S, Grimbacher B, Caballero Garcia de Oteyza A, Marks R, Pfeifer D, Nieters A, Proietti M, Warnatz K, Schmitt-Graeff A. J Clin Immunol. 2021 Aug;41(6):1250-1265. Epub 2021 Apr 19.
  89. Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice. Wang L, Aschenbrenner D, Zeng Z, Cao X, Mayr D, Mehta M, Capitani M, Warner N, Pan J, Wang L, Li Q, Zuo T, Cohen-Kedar S, Lu J, Ardy RC, Mulder DJ,
    Dissanayake D, Peng K, Huang Z, Li X, Wang Y, Wang X, Li S, Bullers S, Gammage AN, Warnatz K, Schiefer AI, Krivan G, Goda V, Kahr WHA, Lemaire M; Genomics England Research Consortium, Lu CY, Siddiqui I, Surette MG, Kotlarz D, Engelhardt KR, Griffin HR, Rottapel R, Decaluwe H, Laxer RM, Proietti M, Hambleton S, Elcombe S, Guo CH, Grimbacher B, Dotan I, Ng SC, Freeman SA, Snapper SB, Klein C, Boztug K, Huang Y, Li D, Uhlig HH, Muise AM. Nat Genet. 2021 Apr;53(4):500-510. Epub 2021 Mar 29. Erratum in: Nat Genet. 2022 Feb;54(2):213.
  90. Agammaglobulinemia with normal B-cell numbers in a patient lacking Bob1. J Allergy Clin Immunol. 2021 May;147(5):1977-1980. Kury P, Staniek J, Wegehaupt O, Janowska I, Eckenweiler M, Korinthenberg R, Japaridze N, Pendziwiat M, Helbig I, Verhoeyen E, Jung J, Garcia de Oteyza AC, Proietti M, Phirtskhalaishvili T, Rtskhiladze I, Nielsen PJ, Ehl S, Speckmann C, Rizzi M.  Epub 2021 Feb 9.
  91. HBV evolution and genetic variability: Impact on prevention, treatment and development of antivirals. Glebe D, Goldmann N, Lauber C, Seitz S. Antiviral Research
  92. Conservation of the HBV RNA element epsilon in nackednaviruses reveals ancient origin of protein-primed reverse transcription. Beck J, Seitz S, Lauber C, Nassal M. Proceedings of the National Academy of Sciences 2021.
  93. Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements. Tegtmeyer B, Vieyres G, Todt D, Lauber C, Ginkel C, Engelmann M, Herrmann M, Pfaller CK, Vondran FWR, Broering R, Vafadarnejad E, Saliba AE, Puff C, Baumgärtner W, Miskey C, Ivics Z, Steinmann E, Pietschmann T, Brown RJP. Journal of Virology 2021.
  94. Bioinformatics of virus taxonomy: foundations and tools for developing sequence-based hierarchical classifications. Gorbalenya AE and Lauber C. Current Opinion in Virology 2021.
  95. Deep mining of the Sequence Read Archive reveals bipartite coronavirus genomes and inter-family Spike glycoprotein recombination. Lauber C, Vaas J, Klingler F, Mutz P, Gorbalenya AE, Bartenschlager AE, Seitz S. bioRxiv 2021.
  96. Novel aspects of regulatory T cell dysfunction as a therapeutic target in giant cell arteritis. Adriawan IR, Atschekzei F, Dittrich-Breiholz O, Garantziotis P, Hirsch S, Risser LM, Kosanke M, Schmidt RE, Witte T, Sogkas G. Ann Rheum Dis. 2022 Jan;81(1):124-131.
  97. B cell depletion impairs vaccination-induced CD8+ T cell responses in a type I interferon-dependent manner. Graalmann T, Borst K, Manchanda H, Vaas L, Bruhn M, Graalmann L, Koster M, Verboom M, Hallensleben M, Guzmán CA, Sutter G, Schmidt RE, Witte T, Kalinke U. Ann Rheum Dis.
  98. Haploflow: strain-resolved de novo assembly of viral genomes. Genome Biol 22:212. Fritz A, Bremges A, Deng Z-L, Lesker TR, Götting J, Ganzenmueller T, Sczyrba A, Dilthey A, Klawonn F, McHardy AC. 2021.
  99. EpitopeVec: Linear Epitope Prediction Using Deep Protein Sequence Embeddings. Bioinformatics. Bahai A, Asgari E, Mofrad MRK, Kloetgen A, McHardy AC. Bioinformatics.
  100. Imprint of unconventional T-cell response in acute hepatitis C persists despite successful early antiviral treatment. Du Y, Khera T, Strunz B, Deterding K, Todt D, Woller N, Engelskircher SA, Hardtke S, Port K, Ponzetta A, Steinmann E, Cornberg M, Hengst J, Björkström NK, Wedemeyer H; HepNet Acute HCV Ⅳ Study Group. Eur J Immunol.
  101. Identification of African Elephant Polyomavirus in wild elephants and the creation of a vector expressing its viral tumor antigens to transform elephant primary cells. Pearson VR, Bosse JB, Koyuncu OO, Scherer J, Toruno C, Robinson R, et al. (2021)  PLoS ONE 16(2): e0244334.
  102. Egress of human cytomegalovirus through multivesicular bodies.Flomm F, Soh TK, Britt H, Schneider C, Reimer R, Thalassinos K, Grünewald K, Bosse JB. bioRxiv 2020
  103. A Pathogenic Missense Variant in NFKB1 Causes Common Variable Immunodeficiency Due to Detrimental Protein Damage. Fliegauf M, Krüger R, Steiner S, Hanitsch LG, Büchel S, Wahn V, von Bernuth H, Grimbacher B. Front Immunol. 2021 Apr 27;12:621503.
  104. Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction. Català-Moll F, Ferreté-Bonastre AG, Li T, Weichenhan D, Lutsik P, Ciudad L, Álvarez-Prado ÁF, Rodríguez-Ubreva J, Klemann C, Speckmann C, Vilas-Zornoza A, Abolhassani H, Martínez-Gallo M, Dieli-Crimi R, Rivière JG, Martín-Nalda A, Colobran R, Soler-Palacín P, Kracker S, Hammarström L, Prosper F, Durandy A, Grimbacher B, Plass C, Ballestar E.  Nucleic Acids Res. 2021 May 21;49(9):5057-5073.
  105. Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia Zielen S, Duecker RP, Woelke S, Donath H, Bakhtiar S, Buecker A, Kreyenberg H, Huenecke S, Bader P, Mahlaoui N, Ehl S, El-Helou SM, Pietrucha B, Plebani A, van der Flier M, van Aerde K, Kilic SS, Reda SM, Kostyuchenko L, McDermott E, Galal N, Pignata C, Pérez JLS, Laws HJ, Niehues T, Kutukculer N, Seidel MG, Marques L, Ciznar P, Edgar JDM, Soler-Palacín P, von Bernuth H, Krueger R, Meyts I, Baumann U, Kanariou M, Grimbacher B, Hauck F, Graf D, Granado LIG, Prader S, Reisli I, Slatter M, Rodríguez-Gallego C, Arkwright PD, Bethune C, Deripapa E, Sharapova SO, Lehmberg K, Davies EG, Schuetz C, Kindle G, Schubert R. J Clin Immunol. 2021 Nov;41(8):1878-1892.
  106. Fucosylated lipid nanocarriers loaded with antibiotics efficiently inhibit mycobacterial propagation in human myeloid cells. J Control Release. Durán V, Grabski E, Hozsa C, Becker J, Yasar H, Monteiro JT, Costa B, Koller N, Lueder Y, Wiegmann B, Brandes G, Kaever V, Lehr CM, Lepenies B, Tampé R, Förster R, Bošnjak B, Furch M, Graalmann T, Kalinke U.  2021 Jun 10;334:201-212.  Epub 2021 Apr 16.
  107. Differentiation of viral and autoimmune central nervous system inflammation by kynurenine pathway. Luo Y, Möhn N, Skripuletz T, Senel M, Tumani H, Peßler F, Sühs KW, Stangel M. Ann Clin Transl Neurol. 2021 Dec;8(12):2228-2234. doi: 10.1002/acn3.51383. Epub 2021 Oct 8.
  108. High frequency of variants in genes associated with primary immunodeficiencies in patients with rheumatic diseases with secondary hypogammaglobulinaemia. Sogkas G, Dubrowinskaja N, Adriawan IR, Anim M, Witte T, Schmidt RE, Atschekzei F.  Ann Rheum Dis. 2021 Mar;80(3):392-399.
  109. A condensate-hardening drug blocks RSV replication in vivo. Risso-Ballester J, Galloux M, Cao J, Le Goffic R, Hontonnou F, Jobart-Malfait A, Desquesnes A, Sake SM, Haid S, Du M, Zhang X, Zhang H, Wang Z, Rincheval V, Zhang Y, Pietschmann T, Eléouët JF, Rameix-Welti MA, Altmeyer R. Nature. 2021 Jul;595(7868):596-599. doi: 10.1038/s41586-021-03703-z. Epub 2021 Jul 7. PMID: 34234347.
  110. A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS. Maccari ME, Fuchs S, Kury P, Andrieux G, Völkl S, Bengsch B, Lorenz MR, Heeg M, Rohr J, Jägle S, Castro CN, Groß M, Warthorst U, König C, Fuchs I, Speckmann C, Thalhammer J, Kapp FG, Seidel MG, Dückers G, Schönberger S, Schütz C, Führer M, Kobbe R, Holzinger D, Klemann C, Smisek P, Owens S, Horneff G, Kolb R, Naumann-Bartsch N, Miano M, Staniek J, Rizzi M, Kalina T, Schneider P, Erxleben A, Backofen R, Ekici A, Niemeyer CM, Warnatz K, Grimbacher B, Eibel H, Mackensen A, Frei AP, Schwarz K, Boerries M, Ehl S, Rensing-Ehl A.  J Exp Med. 2021 Feb 1;218(2):e20192191. doi: 10.1084/jem.20192191. PMID: 33170215; PMCID: PMC7658692.
  111. A selectable all-in-one CRISPR prime editing piggyBac transposon allows for highly efficient gene editing in human cell lines. Eggenschwiler R, Gschwendtberger T, Felski C, Jahn C, Langer F, Sterneckert J, Hermann A, Lühmann J, Steinemann D, Haase A, Martin U, Petri S, Cantz T. Sci Rep. 2021 Nov 12;11(1):22154. doi: 10.1038/s41598-021-01689-2. PMID: 34773059; PMCID: PMC8589839.
  112. Activation of cGAS/STING pathway upon paramyxovirus infection. Iampietro M, Dumont C, Mathieu C, Spanier J, Robert J, Charpenay A, Dupichaud S, Dhondt KP, Aurine N, Pelissier R, Ferren M, Mély S, Gerlier D, Kalinke U, Horvat B. iScience. 2021 May 7;24(6):102519. doi: 10.1016/j.isci.2021.102519. PMID: 34142033; PMCID: PMC8188492.
  113. Anti-CD74 IgA autoantibodies in radiographic axial spondyloarthritis: a longitudinal Swedish study. Do L, Granåsen G, Hellman U, Lejon K, Geijer M, Baraliakos X, Witte T, Forsblad-d’Elia H.  Rheumatology (Oxford). 2021 Sep 1;60(9):4085-4093. doi: 10.1093/rheumatology/keaa882. PMID: 33369649; PMCID: PMC8410007.
  114. Biochemically deleterious human NFKB1 variants underlie an autosomal dominant form of common variable immunodeficiency. Li J, Lei WT, Zhang P, Rapaport F, Seeleuthner Y, Lyu B, Asano T, Rosain J, Hammadi B, Zhang Y, Pelham SJ, Spaan AN, Migaud M, Hum D, Bigio B, Chrabieh M, Béziat V, Bustamante J, Zhang SY, Jouanguy E, Boisson-Dupuis S, El Baghdadi J, Aimanianda V, Thoma K, Fliegauf M, Grimbacher B, Korganow AS, Saunders C, Rao VK, Uzel G, Freeman AF, Holland SM, Su HC, Cunningham-Rundles C, Fieschi C, Abel L, Puel A, Cobat A, Casanova JL, Zhang Q, Boisson B. J Exp Med. 2021 Nov 1;218(11):e20210566. doi: 10.1084/jem.20210566. Epub 2021 Sep 2. PMID: 34473196; PMCID: PMC8421261.
  115. BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity. Bittner ZA, Liu X, Mateo Tortola M, Tapia-Abellán A, Shankar S, Andreeva L, Mangan M, Spalinger M, Kalbacher H, Düwell P, Lovotti M, Bosch K, Dickhöfer S, Marcu A, Stevanović S, Herster F, Cardona Gloria Y, Chang TH, Bork F, Greve CL, Löffler MW, Wolz OO, Schilling NA, Kümmerle-Deschner JB, Wagner S, Delor A, Grimbacher B, Hantschel O, Scharl M, Wu H, Latz E, Weber ANR.  J Exp Med. 2021 Nov 1;218(11):e20201656. doi: 10.1084/jem.20201656. Epub 2021 Sep 23. PMID: 34554188; PMCID: PMC8480672.
  116. CARs and beyond: tailoring macrophage-based cell therapeutics to combat solid malignancies. Abdin SM, Paasch D, Morgan M, Lachmann N. J Immunother Cancer. 2021 Aug;9(8):e002741. doi: 10.1136/jitc-2021-002741. PMID: 34462325; PMCID: PMC8407221.
  117. COVID-19 Vaccine-Associated Cerebral Venous Thrombosis in Germany. German Society of Neurology SARS-CoV-2 Vaccination Study Group. Schulz JB, Berlit P, Diener HC, Gerloff C, Greinacher A, Klein C, Petzold GC, Piccininni M, Poli S, Röhrig R, Steinmetz H, Thiele T, Kurth T; Ann Neurol. 2021 Oct;90(4):627-639. doi: 10.1002/ana.26172. Epub 2021 Aug 23. PMID: 34288044; PMCID: PMC8427115.
  118. Discrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs. Ten Hagen NA, Twele F, Meller S, Jendrny P, Schulz C, von Köckritz-Blickwede M, Osterhaus A, Ebbers H, Pink I, Welte T, Manns MP, Illig T, Fathi A, Addo MM, Nitsche A, Puyskens A, Michel J, Krause E, Ehmann R, von Brunn A, Ernst C, Zwirglmaier K, Wölfel R, Nau A, Philipp E, Engels M, Schalke E, Volk HA. Front Med (Lausanne). 2021 Nov 18;8:749588. doi: 10.3389/fmed.2021.749588. PMID: 34869443; PMCID: PMC8636992.
  119. DNA origami signposts for identifying proteins on cell membranes by electron cryotomography. Silvester E, Vollmer B, Pražák V, Vasishtan D, Machala EA, Whittle C, Black S, Bath J, Turberfield AJ, Grünewald K, Baker LA. Cell. 2021 Feb 18;184(4):1110-1121.e16. doi: 10.1016/j.cell.2021.01.033. PMID: 33606980; PMCID: PMC7895908.
  120. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Krämer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga-García R, Schulte-Schrepping J, Kaiser KM, Rieke GJ, Bischoff J, Monin MB, Hoffmeister C, Schlabe S, De Domenico E, Reusch N, Händler K, Reynolds G, Blüthgen N, Hack G, Finnemann C, Nischalke HD, Strassburg CP, Stephenson E, Su Y, Gardner L, Yuan D, Chen D, Goldman J, Rosenstiel P, Schmidt SV, Latz E, Hrusovsky K, Ball AJ, Johnson JM, Koenig PA, Schmidt FI, Haniffa M, Heath JR, Kümmerer BM, Keitel V, Jensen B, Stubbemann P, Kurth F, Sander LE, Sawitzki B; Deutsche COVID-19 OMICS Initiative (DeCOI); Aschenbrenner AC, Schultze JL, Nattermann J. Immunity. 2021 Nov 9;54(11):2650-2669.e14. doi: 10.1016/j.immuni.2021.09.002. Epub 2021 Sep 4. PMID: 34592166; PMCID: PMC8416549.
  121. Endothelial dysfunction contributes to severe COVID-19 in combination with dysregulated lymphocyte responses and cytokine networks. Ruhl L, Pink I, Kühne JF, Beushausen K, Keil J, Christoph S, Sauer A, Boblitz L, Schmidt J, David S, Jäck HM, Roth E, Cornberg M, Schulz TF, Welte T, Höper MM, Falk CS. Signal Transduct Target Ther. 2021 Dec 10;6(1):418. doi: 10.1038/s41392-021-00819-6. PMID: 34893580; PMCID: PMC8661333.
  122. Exploring beyond clinical routine SARS-CoV-2 serology using MultiCoV-Ab to evaluate endemic coronavirus cross-reactivity. Becker M, Strengert M, Junker D, Kaiser PD, Kerrinnes T, Traenkle B, Dinter H, Häring J, Ghozzi S, Zeck A, Weise F, Peter A, Hörber S, Fink S, Ruoff F, Dulovic A, Bakchoul T, Baillot A, Lohse S, Cornberg M, Illig T, Gottlieb J, Smola S, Karch A, Berger K, Rammensee HG, Schenke-Layland K, Nelde A, Märklin M, Heitmann JS, Walz JS, Templin M, Joos TO, Rothbauer U, Krause G, Schneiderhan-Marra N.  Nat Commun. 2021 Feb 19;12(1):1152. doi: 10.1038/s41467-021-20973-3. PMID: 33608538; PMCID: PMC7896075.
  123. Genetic Correction of IL-10RB Deficiency Reconstitutes Anti-Inflammatory Regulation in iPSC-Derived Macrophages. Hoffmann D, Sens J, Brennig S, Brand D, Philipp F, Vollmer Barbosa P, Kuehle J, Steinemann D, Lenz D, Buchegger T, Morgan M, Falk CS, Klein C, Lachmann N, Schambach A.  J Pers Med. 2021 Mar 20;11(3):221. doi: 10.3390/jpm11030221. PMID: 33804706; PMCID: PMC8003874.
  124. Hematopoietic Stem Cell Transplantation Resolves the Immune Deficit Associated with STAT3-Dominant-Negative Hyper-IgE Syndrome. Harrison SC, Tsilifis C, Slatter MA, Nademi Z, Worth A, Veys P, Ponsford MJ, Jolles S, Al-Herz W, Flood T, Cant AJ, Doffinger R, Barcenas-Morales G, Carpenter B, Hough R, Haraldsson Á, Heimall J, Grimbacher B, Abinun M, Gennery AR.  J Clin Immunol. 2021 Jul;41(5):934-943. doi: 10.1007/s10875-021-00971-2. Epub 2021 Feb 1. PMID: 33523338; PMCID: PMC8249289.
  125. Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes. Gámez-Díaz L, Grimbacher B. Biomed J. 2021 Aug;44(4):400-411. doi: 10.1016/j.bj.2021.04.005. Epub 2021 Apr 19. PMID: 34384744; PMCID: PMC8514790.
  126. Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease. Ricke-Hoch M, Stelling E, Lasswitz L, Gunesch AP, Kasten M, Zapatero-Belinchón FJ, Brogden G, Gerold G, Pietschmann T, Montiel V, Balligand JL, Facciotti F, Hirsch E, Gausepohl T, Elbahesh H, Rimmelzwaan GF, Höfer A, Kühnel MP, Jonigk D, Eigendorf J, Tegtbur U, Mink L, Scherr M, Illig T, Schambach A, Pfeffer TJ, Hilfiker A, Haverich A, Hilfiker-Kleiner D.  PLoS One. 2021 Aug 4;16(8):e0255335. doi: 10.1371/journal.pone.0255335. PMID: 34347801; PMCID: PMC8336874.
  127. Impaired respiratory burst contributes to infections in PKCδ-deficient patients. Neehus AL, Moriya K, Nieto-Patlán A, Le Voyer T, Lévy R, Özen A, Karakoc-Aydiner E, Baris S, Yildiran A, Altundag E, Roynard M, Haake K, Migaud M, Dorgham K, Gorochov G, Abel L, Lachmann N, Dogu F, Haskologlu S, İnce E, El-Benna J, Uzel G, Kiykim A, Boztug K, Roderick MR, Shahrooei M, Brogan PA, Abolhassani H, Hancioglu G, Parvaneh N, Belot A, Ikinciogullari A, Casanova JL, Puel A, Bustamante J. J Exp Med. 2021 Sep 6;218(9):e20210501. doi: 10.1084/jem.20210501. Epub 2021 Jul 15. PMID: 34264265; PMCID: PMC8288504.
  128. Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations. Thalhammer J, Kindle G, Nieters A, Rusch S, Seppänen MRJ, Fischer A, Grimbacher B, Edgar D, Buckland M, Mahlaoui N, Ehl S; European Society for Immunodeficiencies Registry Working Party.  J Allergy Clin Immunol. 2021 Nov;148(5):1332-1341.e5. doi: 10.1016/j.jaci.2021.04.015. Epub 2021 Apr 23. PMID: 33895260.
  129. Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20. Stadler D, Kächele M, Jones AN, Hess J, Urban C, Schneider J, Xia Y, Oswald A, Nebioglu F, Bester R, Lasitschka F, Ringelhan M, Ko C, Chou WM, Geerlof A, van de Klundert MA, Wettengel JM, Schirmacher P, Heikenwälder M, Schreiner S, Bartenschlager R, Pichlmair A, Sattler M, Unger K, Protzer U. EMBO Rep. 2021 Jun 4;22(6):e49568. doi: 10.15252/embr.201949568. Epub 2021 May 9. PMID: 33969602; PMCID: PMC8183418.
  130. iPS Cell-Based Model for MAPT Haplotype as a Risk Factor for Human Tauopathies Identifies No Major Differences in TAU Expression. Strauß T, Marvian-Tayaranian A, Sadikoglou E, Dhingra A, Wegner F, Trümbach D, Wurst W, Heutink P, Schwarz SC, Höglinger GU. Front Cell Dev Biol. 2021 Aug 31;9:726866. doi: 10.3389/fcell.2021.726866. PMID: 34532319; PMCID: PMC8438159.
  131. iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia. Dannenmann B, Klimiankou M, Oswald B, Solovyeva A, Mardan J, Nasri M, Ritter M, Zahabi A, Arreba-Tutusaus P, Mir P, Stein F, Kandabarau S, Lachmann N, Moritz T, Morishima T, Konantz M, Lengerke C, Ripperger T, Steinemann D, Erlacher M, Niemeyer CM, Zeidler C, Welte K, Skokowa J. Cell Stem Cell. 2021 May 6;28(5):906-922.e6. doi: 10.1016/j.stem.2021.03.023. Epub 2021 Apr 23. Erratum in: Cell Stem Cell. 2023 Sep 7;30(9):1282. PMID: 33894142.
  132. Is LRP2 Involved in Leptin Transport over the Blood-Brain Barrier and Development of Obesity? Sandin ES, Folberth J, Müller-Fielitz H, Pietrzik CU, Herold E, Willnow TE, Pfluger PT, Nogueiras R, Prevot V, Krey T, Schwaninger M.  Int J Mol Sci. 2021 May 8;22(9):4998. doi: 10.3390/ijms22094998. PMID: 34066779; PMCID: PMC8125945.
  133. Janus kinase inhibitors for the therapy of atopic dermatitis. Traidl S, Freimooser S, Werfel T.  Allergol Select. 2021 Aug 27;5:293-304. doi: 10.5414/ALX02272E. PMID: 34532638; PMCID: PMC8439108.
  134. Liver-Resident Bystander CD8+ T Cells Contribute to Liver Disease Pathogenesis in Chronic Hepatitis D Virus Infection. Kefalakes H, Horgan XJ, Jung MK, Amanakis G, Kapuria D, Bolte FJ, Kleiner DE, Koh C, Heller T, Rehermann B. Gastroenterology. 2021 Nov;161(5):1567-1583.e9. doi: 10.1053/j.gastro.2021.07.027. Epub 2021 Jul 21. PMID: 34302839; PMCID: PMC10263257.
  135. Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP). Horn A, Krist L, Lieb W, Montellano FA, Kohls M, Haas K, Gelbrich G, Bolay-Gehrig SJ, Morbach C, Reese JP, Störk S, Fricke J, Zoller T, Schmidt S, Triller P, Kretzler L, Rönnefarth M, Von Kalle C, Willich SN, Kurth F, Steinbeis F, Witzenrath M, Bahmer T, Hermes A, Krawczak M, Reinke L, Maetzler C, Franzenburg J, Enderle J, Flinspach A, Vehreschild J, Schons M, Illig T, Anton G, Ungethüm K, Finkenberg BC, Gehrig MT, Savaskan N, Heuschmann PU, Keil T, Schreiber S.  Infection. 2021 Dec;49(6):1277-1287. doi: 10.1007/s15010-021-01707-5. Epub 2021 Oct 12. PMID: 34642875; PMCID: PMC8508400.
  136. Mapping the human genetic architecture of COVID-19. COVID-19 Host Genetics Initiative. Nature. 2021 Dec;600(7889):472-477. doi: 10.1038/s41586-021-03767-x. Epub 2021 Jul 8. PMID: 34237774; PMCID: PMC8674144.
  137. Neurological symptoms and complications in predominantly hospitalized COVID-19 patients: Results of the European multinational Lean European Open Survey on SARS-Infected Patients (LEOSS). Kleineberg NN, Knauss S, Gülke E, Pinnschmidt HO, Jakob CEM, Lingor P, Hellwig K, Berthele A, Höglinger G, Fink GR, Endres M, Gerloff C, Klein C, Stecher M, Classen AY, Rieg S, Borgmann S, Hanses F, Rüthrich MM, Hower M, Tometten L, Haselberger M, Piepel C, Merle U, Dolff S, Degenhardt C, Jensen BO, Vehreschild MJGT, Erber J, Franke C, Warnke C; LEOSS Study Group.  Eur J Neurol. 2021 Dec;28(12):3925-3937. doi: 10.1111/ene.15072. Epub 2021 Sep 3. PMID: 34411383; PMCID: PMC8444823.
  138. Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Krenn V, Bosone C, Burkard TR, Spanier J, Kalinke U, Calistri A, Salata C, Rilo Christoff R, Pestana Garcez P, Mirazimi A, Knoblich JA. Cell Stem Cell. 2021 Aug 5;28(8):1362-1379.e7. doi: 10.1016/j.stem.2021.03.004. Epub 2021 Apr 9. PMID: 33838105; PMCID: PMC7611471.
  139. Outcomes of SARS-CoV-2 Infections in Patients with Neurodegenerative Diseases in the LEOSS Cohort. Huber MK, Raichle C, Lingor P, Synofzik M, Borgmann S, Erber J, Tometten L, Rimili W, Dolff S, Wille K, Knauss S, Piepel C, Lanznaster J, Rieg S, Prasser F, Pilgram L, Spottke A, Klockgether T, Klein C, Hopfner F, Höglinger GU; LEOSS Study Group. Mov Disord. 2021 Apr;36(4):791-793. doi: 10.1002/mds.28554. Epub 2021 Feb 27. PMID: 33638915; PMCID: PMC8014567.
  140. Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation. Iljazovic A, Roy U, Gálvez EJC, Lesker TR, Zhao B, Gronow A, Amend L, Will SE, Hofmann JD, Pils MC, Schmidt-Hohagen K, Neumann-Schaal M, Strowig T. Mucosal Immunol. 2021 Jan;14(1):113-124. doi: 10.1038/s41385-020-0296-4. Epub 2020 May 20. PMID: 32433514; PMCID: PMC7790746.
  141. Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation. Häge S, Sonntag E, Svrlanska A, Borst EM, Stilp AC, Horsch D, Müller R, Kropff B, Milbradt J, Stamminger T, Schlötzer-Schrehardt U, Marschall M. Viruses. 2021 Jan 22;13(2):165. doi: 10.3390/v13020165. PMID: 33499341; PMCID: PMC7911381.
  142. Prothrombotic immune thrombocytopenia after COVID-19 vaccination. Tiede A, Sachs UJ, Czwalinna A, Werwitzke S, Bikker R, Krauss JK, Donnerstag F, Weißenborn K, Höglinger G, Maasoumy B, Wedemeyer H, Ganser A. Blood. 2021 Jul 29;138(4):350-353. doi: 10.1182/blood.2021011958. PMID: 34323939; PMCID: PMC8084604.
  143. Rescue from Pseudomonas aeruginosa Airway Infection via Stem Cell Transplantation. Brinkert K, Hedtfeld S, Burhop A, Gastmeier R, Gad P, Wedekind D, Kloth C, Rothschuh J, Lachmann N, Hetzel M, Jirmo AC, Lopez-Rodriguez E, Brandenberger C, Hansen G, Schambach A, Ackermann M, Tümmler B, Munder A.  Mol Ther. 2021 Mar 3;29(3):1324-1334. doi: 10.1016/j.ymthe.2020.12.003. Epub 2020 Dec 3. PMID: 33279724; PMCID: PMC7935663.
  144. Residual low HDV viraemia is associated HDV RNA relapse after PEG-IFNa-based antiviral treatment of hepatitis delta: Results from the HIDIT-II study Liver journal. Birgit Bremer, Olympia E. Anastasiou, Svenja Hardtke, Florin Alexandru Caruntu, Manuela G. Curescu, Kendal Yalcin, Ulus S. Akarca, Selim Gürel, Stefan Zeuzem, Andreas Erhardt, Stefan Lüth, George V. Papatheodoridis, Monica Radu, Ramazan Idilman, Michael P. Manns, Markus Cornberg, Cihan Yurdaydin, Heiner Wedemeyer. First published: 20 November 2020 https://doi.org/10.1111/liv.14740
  145. Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells. Delacher M, Simon M, Sanderink L, Hotz-Wagenblatt A, Wuttke M, Schambeck K, Schmidleithner L, Bittner S, Pant A, Ritter U, Hehlgans T, Riegel D, Schneider V, Groeber-Becker FK, Eigenberger A, Gebhard C, Strieder N, Fischer A, Rehli M, Hoffmann P, Edinger M, Strowig T, Huehn J, Schmidl C, Werner JM, Prantl L, Brors B, Imbusch CD, Feuerer M. Immunity. 2021 Apr 13;54(4):702-720.e17. doi: 10.1016/j.immuni.2021.03.007. Epub 2021 Mar 30. PMID: 33789089; PMCID: PMC8050210.
  146. Swarm Learning for decentralized and confidential clinical machine learning. Warnat-Herresthal S, Schultze H, Shastry KL, Manamohan S, Mukherjee S, Garg V, Sarveswara R, Händler K, Pickkers P, Aziz NA, Ktena S, Tran F, Bitzer M, Ossowski S, Casadei N, Herr C, Petersheim D, Behrends U, Kern F, Fehlmann T, Schommers P, Lehmann C, Augustin M, Rybniker J, Altmüller J, Mishra N, Bernardes JP, Krämer B, Bonaguro L, Schulte-Schrepping J, De Domenico E, Siever C, Kraut M, Desai M, Monnet B, Saridaki M, Siegel CM, Drews A, Nuesch-Germano M, Theis H, Heyckendorf J, Schreiber S, Kim-Hellmuth S; COVID-19 Aachen Study (COVAS); Nattermann J, Skowasch D, Kurth I, Keller A, Bals R, Nürnberg P, Rieß O, Rosenstiel P, Netea MG, Theis F, Mukherjee S, Backes M, Aschenbrenner AC, Ulas T; Deutsche COVID-19 Omics Initiative (DeCOI); Breteler MMB, Giamarellos-Bourboulis EJ, Kox M, Becker M, Cheran S, Woodacre MS, Goh EL, Schultze JL.  Nature. 2021 Jun;594(7862):265-270. doi: 10.1038/s41586-021-03583-3. Epub 2021 May 26. PMID: 34040261; PMCID: PMC8189907.
  147. The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia. Lühmann JL, Stelter M, Wolter M, Kater J, Lentes J, Bergmann AK, Schieck M, Göhring G, Möricke A, Cario G, Žaliová M, Schrappe M, Schlegelberger B, Stanulla M, Steinemann D.  Cancers (Basel). 2021 Aug 30;13(17):4388. doi: 10.3390/cancers13174388. PMID: 34503197; PMCID: PMC8431583.
  148. The effect of keratinized mucosa on the severity of peri-implant mucositis differs between periodontally healthy subjects and the general population: a cross-sectional study. Kabir L, Stiesch M, Grischke J.  Clin Oral Investig. 2021 Mar;25(3):1183-1193. doi: 10.1007/s00784-020-03422-1. Epub 2020 Jul 1. PMID: 32607828; PMCID: PMC7878216.
  149. The expansion of human T-bethighCD21low B cells is T cell dependent. Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K.  Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 8. PMID: 34623902.
  150. The human oral phageome. Szafrański SP, Slots J, Stiesch M.  Periodontol 2000. 2021 Jun;86(1):79-96. doi: 10.1111/prd.12363. Epub 2021 Mar 10. PMID: 33690937.
  151. The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection. Krüger N, Rocha C, Runft S, Krüger J, Färber I, Armando F, Leitzen E, Brogden G, Gerold G, Pöhlmann S, Hoffmann M, Baumgärtner W.  Int J Mol Sci. 2021 Sep 30;22(19):10636. doi: 10.3390/ijms221910636. PMID: 34638978; PMCID: PMC8508926.
  152. Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch. O’Toole Á, Hill V, Pybus OG, Watts A, Bogoch II, Khan K, Messina JP; COVID-19 Genomics UK (COG-UK) consortium; Network for Genomic Surveillance in South Africa (NGS-SA); Brazil-UK CADDE Genomic Network; Tegally H, Lessells RR, Giandhari J, Pillay S, Tumedi KA, Nyepetsi G, Kebabonye M, Matsheka M, Mine M, Tokajian S, Hassan H, Salloum T, Merhi G, Koweyes J, Geoghegan JL, de Ligt J, Ren X, Storey M, Freed NE, Pattabiraman C, Prasad P, Desai AS, Vasanthapuram R, Schulz TF, Steinbrück L, Stadler T; Swiss Viollier Sequencing Consortium; Parisi A, Bianco A, García de Viedma D, Buenestado-Serrano S, Borges V, Isidro J, Duarte S, Gomes JP, Zuckerman NS, Mandelboim M, Mor O, Seemann T, Arnott A, Draper J, Gall M, Rawlinson W, Deveson I, Schlebusch S, McMahon J, Leong L, Lim CK, Chironna M, Loconsole D, Bal A, Josset L, Holmes E, St George K, Lasek-Nesselquist E, Sikkema RS, Oude Munnink B, Koopmans M, Brytting M, Sudha Rani V, Pavani S, Smura T, Heim A, Kurkela S, Umair M, Salman M, Bartolini B, Rueca M, Drosten C, Wolff T, Silander O, Eggink D, Reusken C, Vennema H, Park A, Carrington C, Sahadeo N, Carr M, Gonzalez G; SEARCH Alliance San Diego; National Virus Reference Laboratory; SeqCOVID-Spain; Danish Covid-19 Genome Consortium (DCGC); Communicable Diseases Genomic Network (CDGN); Dutch National SARS-CoV-2 surveillance program; Division of Emerging Infectious Diseases (KDCA); de Oliveira T, Faria N, Rambaut A, Kraemer MUG. Wellcome Open Res. 2021 Sep 17;6:121. doi: 10.12688/wellcomeopenres.16661.2. PMID: 34095513; PMCID: PMC8176267.
  153. Tutorial: assessing metagenomics software with the CAMI benchmarking toolkit. Meyer F, Lesker TR, Koslicki D, Fritz A, Gurevich A, Darling AE, Sczyrba A, Bremges A, McHardy AC.  Nat Protoc. 2021 Apr;16(4):1785-1801. doi: 10.1038/s41596-020-00480-3. Epub 2021 Mar 1. PMID: 33649565.
  154. Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages. Eisfeld HS, Simonis A, Winter S, Chhen J, Ströh LJ, Krey T, Koch M, Theobald SJ, Rybniker J.  Viruses. 2021 Oct 15;13(10):2076. doi: 10.3390/v13102076. PMID: 34696506; PMCID: PMC8538122.
  155. Vulnerability to Meningococcal Disease in Immunodeficiency Due to a Novel Pathogenic Missense Variant in NFKB1. Anim M, Sogkas G, Schmidt G, Dubrowinskaja N, Witte T, Schmidt RE, Atschekzei F. Front Immunol. 2021 Dec 24;12:767188. doi: 10.3389/fimmu.2021.767188. Erratum in: Front Immunol. 2023 May 10;14:1212029. PMID: 35003082; PMCID: PMC8738076.
  156. What can clinical immunology learn from inborn errors of epigenetic regulators? Camacho-Ordonez N, Ballestar E, Timmers HTM, Grimbacher B.  J Allergy Clin Immunol. 2021 May;147(5):1602-1618. doi: 10.1016/j.jaci.2021.01.035. Epub 2021 Feb 17. PMID: 33609625.
  157. Role of Transforming Growth Factor-β1 in Regulating Fetal-Maternal Immune Tolerance in Normal and Pathological Pregnancy D. Yang, F. Dai, M. Yuan, Y. Zheng, S. Liu, Z. Deng, et al. Frontiers in Immunology 2021 Vol. 12 Pages 689181 DOI: 10.3389/fimmu.2021.689181
  158. Non-Appearance of the RSV Season 2020/21 During the COVID-19 Pandemic–Prospective, Multicenter Data on the Incidence of Respiratory Syncytial Virus (RSV) Infection. Lange M, Happle C, Hamel J, Dördelmann M, Bangert M, Kramer R, Eberhardt F, Panning M, Heep A, Hansen G, Wetzke M. Dtsch Arztebl Int. 2021 Aug 23;118(33-34):561-562. doi: 10.3238/arztebl.m2021.0300. PMID: 34725031; PMCID: PMC8579425.
  159. Differentiation of viral and autoimmune central nervous system inflammation by kynurenine pathway Y. Luo, N. Möhn, T. Skripuletz, M. Senel, H. Tumani, F. Peßler, et al. Ann Clin Transl Neurol 2021 Vol. 8 Issue 12 Pages 2228-2234 Accession Number: 34623755 PMCID: PMC8670317 DOI: 10.1002/acn3.51383
  1. Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype. Thöming JG, Tomasch J, Preusse M, Koska M, Grahl N, Pohl S, Willger SD, Kaever V, Müsken M, Häussler S. NPJ Biofilms Microbiomes. 2020 Jan 10;6:2.
  2. Cancer Tendency in a Patient with ZNF341 Deficiency. Cekic S, Hartberger JM, Frey-Jakobs S, Huriyet H, Hortoglu MB, Neubauer JC, Karali Y, Abakay CD, Saraydaroglu O, Cavas T, Grimbacher B, Kilic SS J Clin Immunol. 2020 Apr;40(3):534-538.
  3. The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13. Mulas F, Wang X, Song S, Nishanth G, Yi W, Brunn A, Larsen PK, Isermann B, Kalinke U, Barragan A, Naumann M, Deckert M, Schlüter D. . Cell Mol Immunol. 2020 Feb 5. doi: 10.1038/s41423-020-0362-6. Epub ahead of print. PMID: 32024978.
  4. Selective reconstitution of IFN‑γ gene function in Ncr1+ NK cells is sufficient to control systemic vaccinia virus infection. Borst K, Flindt S, Blank P, Larsen PK, Chhatbar C, Skerra J, Spanier J, Hirche C, König M, Alanentalo T, Hafner M, Waibler Z, Pfeffer K, Sexl V, Sutter G, Müller W, Graalmann T, Kalinke U. PLoS Pathog. 2020 Feb 5;16(2):e1008279. doi: 10.1371/journal.ppat.1008279. PMID: 32023327; PMCID: PMC7028289.
  5. Targeting Kaposi’s Sarcoma-Associated Herpesvirus ORF21 Tyrosine Kinase and Viral Lytic Reactivation by Tyrosine Kinase Inhibitors Approved for Clinical Use. Beauclair G, Naimo E, Dubich T, Rückert J, Koch S, Dhingra A, Wirth D, Schulz TF.  J Virol. 2020 Feb 14;94(5). pii: e01791-19 5,103 doi: 10.1128/JVI.01791-19 Prim. Publication
  6. TCR repertoire analysis reveals phosphoantigen-induced polyclonal proliferation of Vγ9Vδ2 T cells in neonates and adults. Fichtner AS, Bubke A, Rampoldi F, Wilharm A, Tan L, Steinbrück L, Schultze-Florey C, von Kaisenberg C, Prinz I, Herrmann T, Ravens S. J Leukoc Biol. 2020 Feb 17. doi: 10.1002/JLB.1MA0120-427RR.
  7. Efficient homing of T cells via afferent lymphatics requires mechanical arrest and integrin-supported chemokine guidance. Martens R, Permanyer M, Werth K, Yu K, Braun A, Halle O, Halle S, Patzer GE, Bošnjak B, Kiefer F, Janssen A, Friedrichsen M, Poetzsch J, Kohli K, Lueder Y, Gutierrez Jauregui R, Eckert N, Worbs T, Galla M, Förster R. Nat Commun. 2020 Feb 28;11(1):1114. doi: 10.1038/s41467-020-14921-w. PMID: 32111837; PMCID: PMC7048855.
  8. Efficient acute and chronic infection of stem cell-derived hepatocytes by hepatitis C virus. Carpentier A, Sheldon J, Vondran FWR, Brown RJ, Pietschmann T. Gut. 2020 Sep;69(9):1659-1666. doi: 10.1136/gutjnl-2019-319354. Epub 2020 Feb 29. PMID: 32114504; PMCID: PMC7456736.
  9. An Integrated Metagenome Catalog Reveals New Insights into the Murine Gut Microbiome. Lesker TR, Durairaj AC, Gálvez EJC, Lagkouvardos I, Baines JF, Clavel T, Sczyrba A, McHardy AC, Strowig T.  Cell Rep. 2020 Mar 3;30(9):2909-2922.e6. doi: 10.1016/j.celrep.2020.02.036. PMID: 32130896; PMCID: PMC7059117.
  10. Advances in cytomegalovirus (CMV) biology and its relationship to health, diseases, and aging. Nikolich-Žugich J, Čicin-Šain L, Collins-McMillen D, Jackson S, Oxenius A, Sinclair J, Snyder C, Wills M, Lemmermann N. Geroscience. 2020 Apr;42(2):495-504. doi: 10.1007/s11357-020-00170-8. Epub 2020 Mar 11. PMID: 32162210; PMCID: PMC7205956.
  11. Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease. Lang J, Bohn P, Bhat H, Jastrow H, Walkenfort B, Cansiz F, Fink J, Bauer M, Olszewski D, Ramos-Nascimento A, Duhan V, Friedrich SK, Becker KA, Krawczyk A, Edwards MJ, Burchert A, Huber M, Friebus-Kardash J, Göthert JR, Hardt C, Probst HC, Schumacher F, Köhrer K, Kleuser B, Babiychuk EB, Sodeik B, Seibel J, Greber UF, Lang PA, Gulbins E, Lang KS. Nat Commun. 2020 Mar 12;11(1):1338. doi: 10.1038/s41467-020-15072-8. PMID: 32165633; PMCID: PMC7067866.
  12. Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection. Schober K, Voit F, Grassmann S, Müller TR, Eggert J, Jarosch S, Weißbrich B, Hoffmann P, Borkner L, Nio E, Fanchi L, Clouser CR, Radhakrishnan A, Mihatsch L, Lückemeier P, Leube J, Dössinger G, Klein L, Neuenhahn M, Oduro JD, Cicin-Sain L, Buchholz VR, Busch DH. Nat Immunol. 2020 Apr;21(4):434-441. doi: 10.1038/s41590-020-0628-2. Epub 2020 Mar 16. PMID: 32205883.
  13. Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry. Blockus S, Sake SM, Wetzke M, Grethe C, Graalmann T, Pils M, Le Goffic R, Galloux M, Prochnow H, Rox K, Hüttel S, Rupcic Z, Wiegmann B, Dijkman R, Rameix-Welti MA, Eléouët JF, Duprex WP, Thiel V, Hansen G, Brönstrup M, Haid S, Pietschmann T. Antiviral Res. 2020 May;177:104774. doi: 10.1016/j.antiviral.2020.104774. Epub 2020 Mar 18. PMID: 32197980.
  14. Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome. Béziat V, Tavernier SJ, Chen YH, Ma CS, Materna M, Laurence A, Staal J, Aschenbrenner D, Roels L, Worley L, Claes K, Gartner L, Kohn LA, De Bruyne M, Schmitz-Abe K, Charbonnier LM, Keles S, Nammour J, Vladikine N, Maglorius Renkilaraj MRL, Seeleuthner Y, Migaud M, Rosain J, Jeljeli M, Boisson B, Van Braeckel E, Rosenfeld JA, Dai H, Burrage LC, Murdock DR, Lambrecht BN, Avettand- Fenoel V, Vogel TP; Undiagnosed Diseases Network, Esther CR, Haskologlu S, Dogu F, Ciznar P, Boutboul D, Ouachée-Chardin M, Amourette J, Lebras MN, Gauvain C, Tcherakian C, Ikinciogullari A, Beyaert R, Abel L, Milner JD, Grimbacher B, Couderc LJ, Butte MJ, Freeman AF, Catherinot É, Fieschi C, Chatila TA, Tangye SG, Uhlig HH, Haerynck F, Casanova JL, Puel A. J Exp Med. 2020 Jun 1;217(6):e20191804.“
  15. Human γδ TCR Repertoires in Health and Disease. Fichtner AS, Ravens S, Prinz I.  Cells. 2020 Mar 26;9(4):800. doi: 10.3390/cells9040800. PMID: 32225004; PMCID: PMC7226320.
  16. IL-17 regulates DC migration to the peribronchial LNs and allergen presentation in experimental allergic asthma. Jirmo AC, Busse M, Happle C, Skuljec J, Dalüge K, Habener A, Grychtol R, DeLuca DS, Breiholz OD, Prinz I, Hansen G.Eur J Immunol. 2020 Jul;50(7):1019-1033. doi: 10.1002/eji.201948409. Epub 2020 Mar 29. PMID: 32142593.
  17. Genetic determinants of Pseudomonas aeruginosa fitness during biofilm growth. Schinner S, Engelhardt F, Preusse M, Thöming JG, Tomasch J, Häussler S. Biofilm. 2020 Apr 2;2:100023.
  18. Deubiquitinating enzymes (DUBs): DoUBle-edged swords in CNS autoimmunity. J Neuroinflammation. Ruan J, Schlüter D, Wang X. 2020 Apr 6;17(1):102. doi: 10.1186/s12974-020-01783-8. PMID: 32248814; PMCID: PMC7132956.
  19. Peripheral Blood Lymphocyte Phenotype Differentiates Secondary Antibody Deficiency in Rheumatic Disease from Primary Antibody Deficiency. Jablonka A, Etemadi H, Adriawan IR, Ernst D, Jacobs R, Buyny S, Witte T, Schmidt RE, Atschekzei F, Sogkas G. J Clin Med. 2020 Apr 7;9(4):1049. doi: 10.3390/jcm9041049. PMID: 32272789; PMCID: PMC7230453.
  20. Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations. Lorenzini T, Fliegauf M, Klammer N, Frede N, Proietti M, Bulashevska A, Camacho-Ordonez N, Varjosalo M, Kinnunen M, de Vries E, van der Meer JWM, Ameratunga R, Roifman CM, Schejter YD, Kobbe R, Hautala T, Atschekzei F, Schmidt RE, Schröder C, Stepensky P, Shadur B, Pedroza LA, van der Flier M, Martínez-Gallo M, Gonzalez-Granado LI, Allende LM, Shcherbina A, Kuzmenko N, Zakharova V, Neves JF, Svec P, Fischer U, Ip W, Bartsch O, Barış S, Klein C, Geha R, Chou J, Alosaimi M, Weintraub L, Boztug K, Hirschmugl T, Dos Santos Vilela MM, Holzinger D, Seidl M, Lougaris V, Plebani A, Alsina L, Piquer-Gibert M, Deyà-Martínez A, Slade CA, Aghamohammadi A, Abolhassani H, Hammarström L, Kuismin O, Helminen M, Allen HL, Thaventhiran JE, Freeman AF, Cook M, Bakhtiar S, Christiansen M, Cunningham-Rundles C, Patel NC, Rae W, Niehues T, Brauer N, Syrjänen J, Seppänen MRJ, Burns SO, Tuijnenburg P, Kuijpers TW; NIHR-BioResource – Rare Diseases Consortium, Warnatz K, Grimbacher B. J Allergy Clin Immunol. 2020 Apr 9:S0091-6749(20)30422-X.
  21. Nonpermissive bone marrow environment impairs early B-cell development in common variable immunodeficiency. Troilo A, Wehr C, Janowska I, Venhoff N, Thiel J, Rawluk J, Frede N, Staniek J, Lorenzetti R, Schleyer MT, Herget GW, Konstantinidis L, Erlacher M, Proietti M, Camacho-Ordonez N, Voll RE, Grimbacher B, Warnatz K, Salzer U, Rizzi M. Blood. 2020 Apr 23;135(17):1452-1457.
  22. S100-Alarmins Are Essential Pilots of Postnatal Innate Immune Adaptation. Viemann D. Front Immunol. 2020 Apr 30;11:688. doi: 10.3389/fimmu.2020.00688. PMID: 32425933; PMCID: PMC7203218.
  23. Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells. Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC. Cell. 2020 May 28;181(5):1080-1096.e19. doi: 10.1016/j.cell.2020.04.022. Epub 2020 May 6. PMID: 32380006.
  24. Differential retention of lymph-borne CD8 memory T cell subsets in the subcapsular sinus of resting and inflamed lymph nodes. Nikolova G, Weiss S, Bosnjak B, Förster R. Cell Mol Immunol. 2020 May 12. doi: 10.1038/s41423-020-0451-6. Epub ahead of print. PMID: 32398805.
  25. Crystal structure of the metaeffector MesI (Lpg2505) from Legionella pneumophila. Machtens DA, Willerding JM, Eschenburg S, Reubold TF. Biochem Biophys Res Commun. 2020 Jun 30;527(3):696-701. doi: 10.1016/j.bbrc.2020.05.027. Epub 2020 May 15. PMID: 32423822.
  26. De novo protein design enables the precise induction of RSV-neutralizing antibodies. Sesterhenn F, Yang C, Bonet J, Cramer JT, Wen X, Wang Y, Chiang CI, Abriata LA, Kucharska I, Castoro G, Vollers SS, Galloux M, Dheilly E, Rosset S, Corthésy P, Georgeon S, Villard M, Richard CA, Descamps D, Delgado T, Oricchio E, Rameix-Welti MA, Más V, Ervin S, Eléouët JF, Riffault S, Bates JT, Julien JP, Li Y, Jardetzky T, Krey T, Correia BE. Science. 2020 May 15;368(6492):eaay5051. doi: 10.1126/science.aay5051.
  27. Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells. Chaudhry MZ, Casalegno-Garduno R, Sitnik KM, Kasmapour B, Pulm AK, Brizic I, Eiz-Vesper B, Moosmann A, Jonjic S, Mocarski ES, Cicin-Sain L. Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):12961-12968. doi: 10.1073/pnas.1914667117. Epub 2020 May 22. Erratum in: Proc Natl Acad Sci U S A. 2020 Aug 3;: PMID: 32444487; PMCID: PMC7293702.
  28. Incidence of SCID in Germany from 2014 to 2015 an ESPED* Survey on Behalf of the API*** Erhebungseinheit für Seltene Pädiatrische Erkrankungen in Deutschland (German Paediatric Surveillance Unit) ** Arbeitsgemeinschaft Pädiatrische Immunologie. Shai S, Perez-Becker R, Andres O, Bakhtiar S, Bauman U, von Bernuth H, Classen CF, Dückers G, El-Helou SM, Gangfuß A, Ghosh S, Grimbacher B, Hauck F, Hoenig M, Husain RA, Kindle G, Kipfmueller F, Klemann C, Krüger R, Lainka E, Lehmberg K, Lohrmann F, Morbach H, Naumann-Bartsch N, Oommen PT, Schulz A, Seidemann K, Speckmann C, Sykora KW, von Kries R, Niehues T.  J Clin Immunol. 2020 Jul;40(5):708-717. doi: 10.1007/s10875-020-00782-x. Epub 2020 May 26. PMID: 32458183.
  29. Safety and efficacy of abatacept in patients with treatment-resistant SARCoidosis (ABASARC) – protocol for a multi-center, single-arm phase IIa trial. Frye BC, Rump IC, Uhlmann A, Schubach F, Ihorst G, Grimbacher B, Zissel G, Quernheim JM.Contemp Clin Trials Commun. 2020 May 29;19:100575. doi: 10.1016/j.conctc.2020.100575. PMID: 32551397; PMCID: PMC7292904.
  30. Clinical Phenotypes and Immunological Characteristics of 18 Egyptian LRBA Deficiency Patients. Meshaal S, El Hawary R, Adel R, Abd Elaziz D, Erfan A, Lotfy S, Hafez M, Hassan M, Johnson M, Rojas-Restrepo J, Gamez-Diaz L, Grimbacher B, Shoman W, Abdelmeguid Y, Boutros J, Galal N, El-Guindy N, Elmarsafy A. J Clin Immunol. 2020 Jun 6.
  31. Chronic Viral Liver Diseases: Approaching the Liver Using T Cell Receptor-Mediated Gene Technologies. Healy K, Pasetto A, Sobkowiak MJ, Soon CF, Cornberg M, Aleman S, Sällberg Chen M. Cells. 2020 Jun 16;9(6):1471. doi: 10.3390/cells9061471. PMID: 32560123; PMCID: PMC7349849.
  32. Acute neonatal Listeria monocytogenes infection causes long-term, organ-specific changes in immune cell subset composition. Zou M, Yang J, Wiechers C, Huehn J. Eur J Microbiol Immunol (Bp). 2020 Jun 19;10(2):98–106. doi: 10.1556/1886.2020.00007. Epub ahead of print. PMID: 32644940; PMCID: PMC7391377.
  33. Reappearance of effector T cells is associated with recovery from COVID-19. EBioMedicine. 2020 Jul;57:102885. doi: 10.1016/j.ebiom.2020.102885. Epub 2020 Jul 7. PMID: 32650275; PMCID: PMC7338277. Odak I, Barros-Martins J, Bošnjak B, Stahl K, David S, Wiesner O, Busch M, Hoeper MM, Pink I, Welte T, Cornberg M, Stoll M, Goudeva L, Blasczyk R, Ganser A, Prinz I, Förster R, Koenecke C, Schultze-Florey CR.
  34. Seropositivity for pathogens associated with chronic infections is a risk factor for all-cause mortality in the elderly: findings from the Memory and Morbidity in Augsburg Elderly (MEMO) Study. Zeeb M, Kerrinnes T, Cicin-Sain L, Guzman CA, Puppe W, Schulz TF, Peters A, Berger K, Castell S, Karch A. Geroscience. 2020 Oct;42(5):1365-1376. doi: 10.1007/s11357-020-00216-x. Epub 2020 Jul 9. PMID: 32648237; PMCID: PMC7525922.
  35. Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV. Theobald SJ, Kreer C, Khailaie S, Bonifacius A, Eiz-Vesper B, Figueiredo C, Mach M, Backovic M, Ballmaier M, Koenig J, Olbrich H, Schneider A, Volk V, Danisch S, Gieselmann L, Ercanoglu MS, Messerle M, Kaisenberg CV, Witte T, Klawonn F, Meyer-Hermann M, Klein F, Stripecke R. PLoS Pathog. 2020 Jul 15;16(7):e1008560. doi: 10.1371/journal.ppat.1008560. PMID: 32667948; PMCID: PMC7363084.
  36. Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth. Ravens S, Fichtner AS, Willers M, Torkornoo D, Pirr S, Schöning J, Deseke M, Sandrock I, Bubke A, Wilharm A, Dodoo D, Egyir B, Flanagan KL, Steinbrück L, Dickinson P, Ghazal P, Adu B, Viemann D, Prinz I.Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18649-18660. doi: 10.1073/pnas.1922588117. Epub 2020 Jul 20. PMID: 32690687; PMCID: PMC7414158.
  37. Differential expression patterns of glycosphingolipids and C-type lectin receptors on immune cells in absence of functional regulatory T cells. Jirmo AC, Rossdam C, Grychtol R, Happle C, Gerardy-Schahn R, Buettner FFR, Hansen G. Immun Inflamm Dis. 2020 Dec;8(4):512-522. doi: 10.1002/iid3.334. Epub 2020 Aug 1. PMID: 32737949; PMCID: PMC7654419.
  38. Combating COVID-19: MVA Vector Vaccines Applied to the Respiratory Tract as Promising Approach Toward Protective Immunity in the Lung. Förster R, Fleige H, Sutter G. Front Immunol. 2020 Aug 7;11:1959. doi: 10.3389/fimmu.2020.01959. PMID: 32849655; PMCID: PMC7426738.
  39. S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants. Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D. Gastroenterology. 2020 Dec;159(6):2130-2145.e5. doi: 10.1053/j.gastro.2020.08.019. Epub 2020 Aug 15. PMID: 32805279.
  40. Global and local envelope protein dynamics of hepatitis C virus determine broad antibody sensitivity. Augestad EH, Castelli M, Clementi N, Ströh LJ, Krey T, Burioni R, Mancini N, Bukh J, Prentoe J. Sci Adv. 2020 Aug 26;6(35):eabb5938. doi: 10.1126/sciadv.abb5938. PMID: 32923643; PMCID: PMC7449684.
  41. Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Setting: The COVID-19 Contact (CoCo) Study in Healthcare Professionals. Behrens GMN, Cossmann A, Stankov MV, Schulte B, Streeck H, Förster R, Bosnjak B, Willenzon S, Boeck AL, Thu Tran A, Thiele T, Graalmann T, Kayser MZ, Zychlinsky Scharff A, Dopfer C, Horke A, Pink I, Witte T, Wetzke M, Ernst D, Jablonka A, Happle C. Infect Dis Ther. 2020 Dec;9(4):837-849. doi: 10.1007/s40121-020-00334-1. Epub 2020 Sep 4. PMID: 32886335; PMCID: PMC7472691.
  42. COVID-19 related reduction in pediatric emergency healthcare utilization – a concerning trend. Dopfer C, Wetzke M, Zychlinsky Scharff A, Mueller F, Dressler F, Baumann U, Sasse M, Hansen G, Jablonka A, Happle C. BMC Pediatr. 2020 Sep 7;20(1):427. doi: 10.1186/s12887-020-02303-6. PMID: 32894080; PMCID: PMC7475725.
  43. Organism-specific depletion of highly abundant RNA species from bacterial total RNA. Engelhardt F, Tomasch J, Häussler S.  Access Microbiol. 2020 Sep 9;2(10):acmi000159. doi: 10.1099/acmi.0.000159. PMID: 33195973; PMCID: PMC7660241.
  44. HCV Glycoprotein Structure and Implications for B-Cell Vaccine Development. Ströh LJ, Krey T. Int J Mol Sci. 2020 Sep 16;21(18):6781. doi: 10.3390/ijms21186781. PMID: 32947858; PMCID: PMC7555785.
  45. Host-induced spermidine production in motile Pseudomonas aeruginosa triggers phagocytic uptake. Felgner S, Preusse M, Beutling U, Stahnke S, Pawar V, Rohde M, Brönstrup M, Stradal T, Häussler S. Elife. 2020 Sep 22;9:e55744. doi: 10.7554/eLife.55744. PMID: 32960172; PMCID: PMC7538158.
  46. Herpes Simplex Virus 2 Counteracts Neurite Outgrowth Repulsion during Infection in a Nerve Growth Factor-Dependent Manner. Kropp KA, López-Muñoz AD, Ritter B, Martín R, Rastrojo A, Srivaratharajan S, Döhner K, Dhingra A, Czechowicz JS, Nagel CH, Sodeik B, Alcami A, Viejo-Borbolla A. J Virol. 2020 Sep 29;94(20):e01370-20. doi: 10.1128/JVI.01370-20. PMID: 32669337; PMCID: PMC7527038.
  47. Host Factors of Favorable Intestinal Microbial Colonization. Pirr S, Viemann D. Front Immunol. 2020 Oct 7;11:584288. doi: 10.3389/fimmu.2020.584288. PMID: 33117398; PMCID: PMC7576995.
  48. The avid competitors of memory inflation. Abassi L, Cicin-Sain L.  Curr Opin Virol. 2020 Oct;44:162-168. doi: 10.1016/j.coviro.2020.08.007. Epub 2020 Oct 8. PMID: 33039898.
  49. MAIT cells are enriched and highly functional in ascites of patients with decompensated liver cirrhosis. Niehaus CE, Strunz B, Cornillet M, Falk CS, Schnieders A, Maasoumy B, Hardtke S, Manns MP, Rm Kraft A, Björkström NK, Cornberg M. Hepatology. 2020 Feb 3. doi: 10.1002/hep.31153. Online ahead of print.
  50. Distinct Polysaccharide Utilization Determines Interspecies Competition between Intestinal Prevotella spp. Gálvez EJC, Iljazovic A, Amend L, Lesker TR, Renault T, Thiemann S, Hao L, Roy U, Gronow A, Charpentier E, Strowig T.  Cell Host Microbe. 2020 Dec 9;28(6):838-852.e6. doi: 10.1016/j.chom.2020.09.012. Epub 2020 Oct 27. PMID: 33113351.
  51. Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods. Bošnjak B, Stein SC, Willenzon S, Cordes AK, Puppe W, Bernhardt G, Ravens I, Ritter C, Schultze-Florey CR, Gödecke N, Martens J, Kleine-Weber H, Hoffmann M, Cossmann A, Yilmaz M, Pink I, Hoeper MM, Behrens GMN, Pöhlmann S, Blasczyk R, Schulz TF, Förster R.  Cell Mol Immunol. 2020 Nov 2:1–9. doi: 10.1038/s41423-020-00573-9. Epub ahead of print. PMID: 33139905; PMCID: PMC7604543.
  52. Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Brown RJP, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran FWR, Krey T, Ströh LJ, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr AW, McClure CP, Randall G, Baktash Y, Ploss A, Thi VLD, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice CM, Pietschmann Sci Adv. 2020 Nov 4;6(45):eabd3233. doi: 10.1126/sciadv.abd3233. PMID: 33148654; PMCID: PMC7673688.
  53. Analysis of the organization and expression patterns of the convergent Pseudomonas aeruginosa lasR/rsaL gene pair uncovers mutual influence. Schinner S, Preusse M, Kesthely C, Häussler S. Mol Microbiol. 2020 Oct 19. doi: 10.1111/mmi.14628. Epub ahead of print. PMID: 33073409.
  54. Influenza A viruses limit NLRP3-NEK7-complex formation and pyroptosis in human macrophages. Boal-Carvalho I, Mazel-Sanchez B, Silva F, Garnier L, Yildiz S, Bonifacio JP, Niu C, Williams N, Francois P, Schwerk N, Schöning J, Carlens J, Viemann D, Hugues S, Schmolke M. EMBO Rep. 2020 Nov 12;21(12):e50421. doi: 10.15252/embr.202050421. Epub ahead of print. PMID: 33180976; PMCID: PMC7726813.
  55. Triple RNA-Seq Reveals Synergy in a Human Virus-Fungus Co-infection Model. Seelbinder B, Wallstabe J, Marischen L, Weiss E, Wurster S, Page L, Löffler C, Bussemer L, Schmitt AL, Wolf T, Linde J, Cicin-Sain L, Becker J, Kalinke U, Vogel J, Panagiotou G, Einsele H, Westermann AJ, Schäuble S, Loeffler J. Cell Rep. 2020 Nov 17;33(7):108389. doi: 10.1016/j.celrep.2020.108389. PMID: 33207195.
  56. Identification of Natural CRISPR Systems and Targets in the Human Microbiome. Cell Host Microbe. Münch PC, Franzosa EA, Stecher B, McHardy AC, Huttenhower C. 2021 Jan 13;29(1):94-106.e4. doi: 10.1016/j.chom.2020.10.010. Epub 2020 Nov 19. PMID: 33217332; PMCID: PMC7813156.
  57. Regulatory B cells control airway hyperreactivity and lung remodeling in a murine asthma model. Dipl-Biol AH, Happle C, Grychtol RM, Skuljec J, Busse M, Dalüge K, Obernolte H, Sewald K, Braun A, Meyer-Bahlburg A, Hansen G. J Allergy Clin Immunol. 2020 Nov 27:S0091-6749(20)31634-1. doi: 10.1016/j.jaci.2020.09.041. Epub ahead of print. PMID: 33249168.
  58. Evolution of Pseudomonas aeruginosa toward higher fitness under standard laboratory conditions. Grekov I, Thöming JG, Kordes A, Häussler S. ISME J. 2020 Dec 3. doi: 10.1038/s41396-020-00841-6. Epub ahead of print. PMID: 33273720.
  59. Hepatitis C reference viruses highlight potent antibody responses and diverse viral functional interactions with neutralising antibodies. Bankwitz D, Bahai A, Labuhn M, Doepke M, Ginkel C, Khera T, Todt D, Ströh LJ, Dold L, Klein F, Klawonn F, Krey T, Behrendt P, Cornberg M, McHardy AC, Pietschmann T. Gut. 2020 Dec 15:gutjnl-2020-321190. doi: 10.1136/gutjnl-2020-321190. Epub ahead of print. PMID: 33323394.
  60. Expression of the MexXY Aminoglycoside Efflux Pump and Presence of an Aminoglycoside-Modifying Enzyme in Clinical Pseudomonas aeruginosa Isolates Are Highly Correlated. Seupt A, Schniederjans M, Tomasch J, Häussler S.  Antimicrob Agents Chemother. 2020 Dec 16;65(1):e01166-20. doi: 10.1128/AAC.01166-20. PMID: 33046496.
  61. Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells. Pae J, Ersching J, Castro TBR, Schips M, Mesin L, Allon SJ, Ordovas-Montanes J, Mlynarczyk C, Melnick A, Efeyan A, Shalek AK, Meyer-Hermann M, Victora GD. J Exp Med. 2021 Apr 5;218(4):e20201699. doi: 10.1084/jem.20201699. PMID: 33332554; PMCID: PMC7754672.
  62. Targeting bioenergetics is key to counteracting the drug-tolerant state of biofilm-grown bacteria. Donnert M, Elsheikh S, Arce-Rodriguez A, Pawar V, Braubach P, Jonigk D, Haverich A, Weiss S, Müsken M, Häussler S.PLoS Pathog. 2020 Dec 22;16(12):e1009126. doi: 10.1371/journal.ppat.1009126. Epub ahead of print. PMID: 33351859.
  63. Double-edged Role of PML Nuclear Bodies during Human Adenovirus Infection. Hofmann S, Stubbe M, Mai J, Schreiner S. Virus Res. 2020 Dec 25:198280. doi: 10.1016/j.virusres.2020.198280. Epub ahead of print. PMID: 33370557.
  64. Evaluation of CD8 T cell killing models with computer simulations of 2-photon imaging experiments. Rastogi A, Robert PA, Halle S, Meyer-Hermann M.PLoS Comput Biol. 2020 Dec 28;16(12):e1008428. doi: 10.1371/journal.pcbi.1008428. Epub ahead of print. PMID: 33370254.
  65. The prefusion structure of herpes simplex virus glycoprotein B. Vollmer B, Pražák V, Vasishtan D, Jefferys EE, Hernandez-Duran A, Vallbracht M, Klupp BG, Mettenleiter TC, Backovic M, Rey FA, Topf M, Grünewald K.  Sci Adv. 2020 Sep 25;6(39):eabc1726. doi: 10.1126/sciadv.abc1726. PMID: 32978151; PMCID: PMC7518877.
  66. Dietary Short-Term Fiber Interventions in Arthritis Patients Increase Systemic SCFA Levels and Regulate Inflammation. Dürholz K, Hofmann J, Iljazovic A, Häger J, Lucas S, Sarter K, Strowig T, Bang H, Rech J, Schett G, Zaiss MM. Nutrients. 2020 Oct 20;12(10):3207. doi: 10.3390/nu12103207. PMID: 33092271; PMCID: PMC7589100.
  67. Double-edge anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods Bosnjak B, Stein SC, Willenzon S, Cordes AK, Puppe W, Bernhardt G, Ravens I, Ritter C, Schultze-Florey CR, Gödecke N, Martens J, Kleine-Weber H, Hoffmann M, Cossmann A, Yilmaz M, Pink I, Hoeper MM, Behrens GMN, Pöhlmann S, Blasczyk R, Schulz TF, Forster R.  Cell Mol Immunol 2020
  68. Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis de Araujo LS, Pessler K, Sühs KW, Novoselova N, Klawonn F, Kuhn M, Kaever V, Müller-Vahl K, Trebst C, Skripuletz T, Stangel M, Pessler F. J Transl Med 2020;18(1):9
    Originalpublikation – IF 4,124
  69. Anti-CD74 IgA autoantibodies in radiographic axial spondyloarthritis; a longitudinal Swedish study. Do L, Granasen G, Hellman U, Lejon K, Geijer M, Baraliakos X, Witte T, Forsblad-d’Elia H. Rheumatology (Oxford) 2020
  70. Absence of cGAS-mediated type I IFN responses in HIV-1-infected T cells Elsner C, Ponnurangam A, Kazmierski J, Zillinger T, Jansen J, Todt D, Döhner K, Xu S, Ducroux A, Kriedemann N, Malassa A, Larsen PK, Hartmann G, Barchet W, Steinmann E, Kalinke U, Sodeik B, Goffinet C.  Proc Natl Acad Sci U S A 2020;117(32):19475-19486
  71. Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation. Gabaev I, Williamson JC, Crozier TWM, Schulz TF, Lehner PJ.  Cell Rep 2020;33(2):108249
  72. Discovery of Novel Latency-Associated Nuclear Antigen Inhibitors as Antiviral Agents Against Kaposi’s Sarcoma-Associated Herpesvirus ACS Kirsch P, Jakob V, Elgaher WAM, Walt C, Oberhausen K, Schulz TF, Empting M.  Chem Biol 2020;15(2):388-395
  73. RNase 7 promotes sensing of self-DNA by human keratinocytes and activates an antiviral immune response Kopfnagel V, Dreyer S, Baumert K, Stark M, Harder J, Hofmann K, Kleine M, Buch A, Sodeik B, Werfel T.  J Invest Dermatol 2020;140(8):1589-1598.e3
  74. Brd/BET Proteins Influence the Genome-Wide Localization of the Kaposi’s Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus Major Latency Proteins Lotke R, Schneeweiss U, Pietrek M, Günther T, Grundhoff A, Weidner-Glunde M, Schulz TF.  Front Microbiol 2020;11:591778
  75. High frequency of variants in genes associated with primary immunodeficiencies in patients with rheumatic diseases with secondary hypogammaglobulinaemia Sogkas G, Dubrowinskaja N, Adriawan IR, Anim M, Witte T, Schmidt RE, Atschekzei F.  Ann Rheum Dis 2020
  76. Dupilumab to treat severe atopic dermatitis in autosomal dominant hyper-IgE syndrome. Sogkas G, Hirsch S, Jablonka A, Witte T, Schmidt RE, Atschekzei F.  Clin Immunol 2020;215:108452
  77. Whole-Genome Approach to Assessing Human Cytomegalovirus Dynamics in Transplant Patients Undergoing Antiviral Therapy Suarez NM, Blyth E, Li K, Ganzenmueller T, Camiolo S, Avdic S, Withers B, Linnenweber-Held S, Gwinner W, Dhingra A, Heim A, Schulz TF, Gunson R, Gottlieb D, Slobedman B, Davison AJ.  Front Cell Infect Microbiol 2020;10:267
  78. Hit-to-lead optimization of a latency-associated nuclear antigen inhibitor against Kaposi’s sarcoma-associated herpesvirus infections Kirsch P, Stein SC, Berwanger A, Rinkes J, Jakob V, Schulz TF, Empting M.  Eur J Med Chem 2020;202:112525
  79. Interleukin-17 cytokines: Effectors and targets in psoriasis-A breakthrough in understanding and treatment. Prinz I, Sandrock I, Mrowietz U. J Exp Med. 2020 Jan 6;217(1). pii: e20191397. doi: 10.1084/jem.20191397.
  80. A novel NFKBIA variant substituting serine 36 of IκBα causes immunodeficiency with warts, bronchiectasis and juvenile rheumatoid arthritis in the absence of ectodermal dysplasia. Sogkas G, Adriawan IR, Ringshausen FC, Baumann U, Schröder C, Klemann C, von Hardenberg S, Schmidt G, Bernd A, Jablonka A, Ernst D, Schmidt RE, Atschekzei F.  Clin Immunol. 2020 Jan;210:108269. 3,969 „doi: 10.1016/j.clim.2019.108269
  81. Recurrent eczema herpeticum – a retrospective European multicenter study evaluating the clinical characteristics of eczema herpeticum cases in atopic dermatitis patients. Seegräber M, Worm M, Werfel T, Svensson A, Novak N, Simon D, Darsow U, Augustin M, Wollenberg A. J Eur Acad Dermatol Venereol. 2020 May;34(5):1074-1079. doi: 10.1111/jdv.16090. Epub 2020 Jan 30. PMID: 31733162.
  82. Clinical, Radiological, and Laboratory Features of Spinal Cord Involvement in Primary Sjögren’s Syndrome. Butryn M, Neumann J, Rolfes L, Bartels C, Wattjes MP, Mahmoudi N, Seeliger T, Konen FF, Thiele T, Witte T, Meuth SG, Skripuletz T, Pawlitzki M. J Clin Med. 2020 May 14;9(5):1482. doi: 10.3390/jcm9051482. PMID: 32423153; PMCID: PMC7290729.
  83. Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation. Iljazovic A, Roy U, Gálvez EJC, Lesker TR, Zhao B, Gronow A, Amend L, Will SE, Hofmann JD, Pils MC, Schmidt-Hohagen K, Neumann-Schaal M, Strowig T. Mucosal Immunol. 2021 Jan;14(1):113-124. doi: 10.1038/s41385-020-0296-4. Epub 2020 May 20. PMID: 32433514; PMCID: PMC7790746.
  84. The Role of Ames Dwarfism and Calorie Restriction on Gut Microbiota. Wiesenborn DS, Gálvez EJC, Spinel L, Victoria B, Allen B, Schneider A, Gesing A, Al-Regaiey KA, Strowig T, Schäfer KH, Masternak MM. J Gerontol A Biol Sci Med Sci. 2020 Jun 18;75(7):e1-e8. doi: 10.1093/gerona/glz236. PMID: 31665244; PMCID: PMC7302176.
  85. Fluorescent Protein Tagging of Adenoviral Proeins PV and PIX Reveals ‚Late Virion Accumulation Compartment‘. Sieber H, Bosse JB, Franken LE, Grünewald K, Dobner T, (2020), PLOS Pathogens
  86. Altered Microbiota, Impaired Quality of Life, Malabsorption, Infection, and Inflammation in CVID Patients With Diarrhoea. van Schewick CM, Nöltner C, Abel S, Burns SO, Workman S, Symes A, Guzman D, Proietti M, Bulashevska A, Moreira F, Soetedjo V, Lowe DM, Grimbacher B. Front Immunol. 2020 Jul 31;11:1654.
  87. Dynamics in protein translation sustaining T cell preparedness. Wolf T, Jin W, Zoppi G, Vogel IA, Akhmedov M, Bleck CKE, Beltraminelli T, Rieckmann JC, Ramirez NJ, Benevento M, Notarbartolo S, Bumann D, Meissner F, Grimbacher B, Mann M, Lanzavecchia A, Sallusto F, Kwee I, Geiger R. Nat Immunol. 2020 Aug;21(8):927-937.
  88. HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection. Bodda C, Reinert LS, Fruhwürth S, Richardo T, Sun C, Zhang BC, Kalamvoki M, Pohlmann A, Mogensen TH, Bergström P, Agholme L, O’Hare P, Sodeik B, Gyrd-Hansen M, Zetterberg H, Paludan SR.  J Exp Med. 2020 Jul 6;217(7):e20191422.
  89. PD-L1 Checkpoint Inhibition Narrows the Antigen-Specific T Cell Receptor Repertoire in Chronic Lymphocytic Choriomeningitis Virus Infection. Klein S, Ghersi D, Manns MP, Prinz I, Cornberg M, Kraft ARM. J Virol. 2020 Aug 31;94(18):e00795-20
  90. Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans. Norona J, Apostolova P, Schmidt D, Ihlemann R, Reischmann N, Taylor G, Köhler N, de Heer J, Heeg S, Andrieux G, Siranosian BA, Schmitt-Graeff A, Pfeifer D, Catalano A, Frew IJ, Proietti M, Grimbacher B, Bulashevska A, Bhatt AS, Brummer T, Clauditz T, Zabelina T, Kroeger N, Blazar BR, Boerries M, Ayuk F, Zeiser R. Blood. 2020 Sep 17;136(12):1442-1455.
  91. A call for a global COVID-19 Neuro Research Coalition. Winkler AS, Knauss S, Schmutzhard E, Leonardi M, Padovani A, Abd-Allah F, Charway-Felli A, Emmrich JV, Umapathi T, Satishchandra P, Hoo FK, Dalmau J, Oreja-Guevara C, Ferreira MLB, Pfausler B, Michael BD, Tagliavini F, Höglinger G, Endres M, Klein C, Hemmer B, Carroll W, Sejvar J, Solomon T. Lancet Neurol. 2020 Jun;19(6):482-484. doi: 10.1016/S1474-4422(20)30150-2. Epub 2020 May 26. Erratum in: Lancet Neurol. 2020 Aug;19(8):e7. PMID: 32470416; PMCID: PMC7250549.
  92. A molecular pore spans the double membrane of the coronavirus replication organelle. Wolff G, Limpens RWAL, Zevenhoven-Dobbe JC, Laugks U, Zheng S, de Jong AWM, Koning RI, Agard DA, Grünewald K, Koster AJ, Snijder EJ, Bárcena M. Science. 2020 Sep 11;369(6509):1395-1398. doi: 10.1126/science.abd3629. Epub 2020 Aug 6. PMID: 32763915; PMCID: PMC7665310.
  93. Biofilm formation on zirconia and titanium over time-An in vivo model study. Desch A, Freifrau von Maltzahn N, Stumpp N, Dalton M, Yang I, Stiesch M.  Clin Oral Implants Res. 2020 Sep;31(9):865-880. doi: 10.1111/clr.13632. Epub 2020 Jul 9. PMID: 32583509.
  94. Cellular Electron Cryo-Tomography to Study Virus-Host Interactions. Quemin ERJ, Machala EA, Vollmer B, Pražák V, Vasishtan D, Rosch R, Grange M, Franken LE, Baker LA, Grünewald K. Annu Rev Virol. 2020 Sep 29;7(1):239-262. doi: 10.1146/annurev-virology-021920-115935. Epub 2020 Jul 6. PMID: 32631159.
  95. Early host-microbe interaction in a peri-implant oral mucosa-biofilm model. Mikolai C, Kommerein N, Ingendoh-Tsakmakidis A, Winkel A, Falk CS, Stiesch M. Cell Microbiol. 2020 Aug;22(8):e13209. doi: 10.1111/cmi.13209. Epub 2020 May 14. PMID: 32329166.
  96. Enabling External Inquiries to an Existing Patient Registry by Using the Open Source Registry System for Rare Diseases: Demonstration of the System Using the European Society for Immunodeficiencies Registry.Scheible R, Kadioglu D, Ehl S, Blum M, Boeker M, Folz M, Grimbacher B, Göbel J, Klein C, Nieters A, Rusch S, Kindle G, Storf H.  JMIR Med Inform. 2020 Oct 7;8(10):e17420. doi: 10.2196/17420. PMID: 33026355; PMCID: PMC7578818.
  97. Evidence for inoculum size and gas interfaces as critical factors in bacterial biofilm formation on magnesium implants in an animal model. Rahim MI, Szafrański SP, Ingendoh-Tsakmakidis A, Stiesch M, Mueller PP. Colloids Surf B Biointerfaces. 2020 Feb;186:110684. doi: 10.1016/j.colsurfb.2019.110684. Epub 2019 Nov 28. PMID: 31812076.
  98. Frequency, characteristics and impact of multiple consecutive nosocomial infections in patients with decompensated liver cirrhosis and ascites. Schultalbers M, Tergast TL, Simon N, Kabbani AR, Kimmann M, Zu Siederdissen CH, Gerbel S, Manns MP, Cornberg M, Maasoumy B. United European Gastroenterol J. 2020 Jun;8(5):567-576. doi: 10.1177/2050640620913732. Epub 2020 Mar 13. PMID: 32213043; PMCID: PMC7268939.
  99. Human γδ TCR Repertoires in Health and Disease. Fichtner AS, Ravens S, Prinz I. Cells. 2020 Mar 26;9(4):800. doi: 10.3390/cells9040800. PMID: 32225004; PMCID: PMC7226320.
  100. Major role of iron uptake systems in the intrinsic extra-intestinal virulence of the genus Escherichia revealed by a genome-wide association study. Galardini M, Clermont O, Baron A, Busby B, Dion S, Schubert S, Beltrao P, Denamur E.  PLoS Genet. 2020 Oct 28;16(10):e1009065. doi: 10.1371/journal.pgen.1009065. PMID: 33112851; PMCID: PMC7592755.
  101. Non-Invasive Luciferase Imaging of Type I Interferon Induction in a Transgenic Mouse Model of Biomaterial Associated Bacterial Infections: Microbial Specificity and Inter-Bacterial Species Interactions. Rahim MI, Winkel A, Lienenklaus S, Stumpp NS, Szafrański SP, Kommerein N, Willbold E, Reifenrath J, Mueller PP, Eisenburger M, Stiesch M.  Microorganisms. 2020 Oct 21;8(10):1624. doi: 10.3390/microorganisms8101624. PMID: 33096869; PMCID: PMC7589032.
  102. Notch and TLR signaling coordinate monocyte cell fate and inflammation. Gamrekelashvili J, Kapanadze T, Sablotny S, Ratiu C, Dastagir K, Lochner M, Karbach S, Wenzel P, Sitnow A, Fleig S, Sparwasser T, Kalinke U, Holzmann B, Haller H, Limbourg FP. Elife. 2020 Jul 29;9:e57007. doi: 10.7554/eLife.57007. PMID: 32723480; PMCID: PMC7413669.
  103. Postinfectious Onset of Myasthenia Gravis in a COVID-19 Patient. Huber M, Rogozinski S, Puppe W, Framme C, Höglinger G, Hufendiek K, Wegner F.  Front Neurol. 2020 Oct 6;11:576153. doi: 10.3389/fneur.2020.576153. PMID: 33123081; PMCID: PMC7573137.
  104. Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning-enabled molecular diagnostics. Khaledi A, Weimann A, Schniederjans M, Asgari E, Kuo TH, Oliver A, Cabot G, Kola A, Gastmeier P, Hogardt M, Jonas D, Mofrad MR, Bremges A, McHardy AC, Häussler S. EMBO Mol Med. 2020 Mar 6;12(3):e10264. doi: 10.15252/emmm.201910264. Epub 2020 Feb 12. PMID: 32048461; PMCID: PMC7059009.
  105. Protecting-Group-Mediated Diastereoselective Synthesis of C4′-Methylated Uridine Analogs and Their Activity against the Human Respiratory Syncytial Virus. Köllmann C, Sake SM, Jones PG, Pietschmann T, Werz DB.  J Org Chem. 2020 Mar 20;85(6):4267-4278. doi: 10.1021/acs.joc.9b03425. Epub 2020 Feb 26. PMID: 32036652.
  106. Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes. Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, Schneider A, Manske K, Sperl LE, Kläger S, Küster B, Wettmarshausen J, Müller C, Laschinger M, Hartmann D, Hüser N, Perocchi F, Schmitt-Kopplin P, Hagn F, Zender L, Hornung V, Borner C, Pichlmair A, Kashkar H, Klingenspor M, Prinz M, Schreiner S, Conrad M, Jost PJ, Zischka H, Steiger K, Krönke M, Zehn D, Protzer U, Heikenwälder M, Knolle PA, Wohlleber D.  J Hepatol. 2020 Dec;73(6):1347-1359. doi: 10.1016/j.jhep.2020.06.026. Epub 2020 Jun 26. PMID: 32598967.
  107. Ten-year follow-up of a randomized controlled clinical trial in chronic hepatitis delta. Wranke A, Hardtke S, Heidrich B, Dalekos G, Yalçin K, Tabak F, Gürel S, Çakaloğlu Y, Akarca US, Lammert F, Häussinger D, Müller T, Wöbse M, Manns MP, Idilman R, Cornberg M, Wedemeyer H, Yurdaydin C.  J Viral Hepat. 2020 Dec;27(12):1359-1368. doi: 10.1111/jvh.13366. Epub 2020 Aug 11. PMID: 32707605.
  108. The Proteome and Secretome of Cortical Brain Cells Infected With Herpes Simplex Virus Front. Niko Hensel, Verena Raker, Benjamin Förthmann, Anna Buch, Beate Sodeik, Andreas Pich, Peter Claus, Neurol., 27 August 2020, Sec. Neuroinfectious Diseases, Volume 11 – 2020, https://doi.org/10.3389/fneur.2020.00844
  109. Triple RNA-Seq Reveals Synergy in a Human Virus-Fungus Co-infection Model. Seelbinder B, Wallstabe J, Marischen L, Weiss E, Wurster S, Page L, Löffler C, Bussemer L, Schmitt AL, Wolf T, Linde J, Cicin-Sain L, Becker J, Kalinke U, Vogel J, Panagiotou G, Einsele H, Westermann AJ, Schäuble S, Loeffler J. Cell Rep. 2020 Nov 17;33(7):108389. doi: 10.1016/j.celrep.2020.108389. PMID: 33207195.
  110. A Novel Triple-Fluorescent HCMV Strain Reveals Gene Expression Dynamics and Anti-Herpesviral Drug Mechanisms. Rand U, Kubsch T, Kasmapour B, Cicin-Sain L. Front Cell Infect Microbiol. 2021 Jan 8;10:536150. doi: 10.3389/fcimb.2020.536150. PMID: 33489928; PMCID: PMC7820782.
  111. Patterns of Autologous and Nonautologous Interactions Between Core Nuclear Egress Complex (NEC) Proteins of α-, β- and γ-Herpesviruses. Häge S, Sonntag E, Borst EM, Tannig P, Seyler L, Bäuerle T, Bailer SM, Lee CP, Müller R, Wangen C, Milbradt J, Marschall M. Viruses. 2020 Mar 11;12(3):303. doi: 10.3390/v12030303. PMID: 32168891; PMCID: PMC7150769.
  112. Cancer Tendency in a Patient with ZNF341 Deficiency
    S. Cekic, J. M. Hartberger, S. Frey-Jakobs, H. Huriyet, M. B. Hortoglu, J. C. Neubauer, et al.
    Journal of Clinical Immunology 2020 Vol. 40 Issue 3 Pages 534-538 DOI: 10.1007/s10875-020-00756-z
  113. B cell hyperactivation in an Ackr4-deficient mouse strain is not caused by lack of ACKR4 expression N. Eckert, K. Werth, S. Willenzon, L. Tan and R. Förster Journal of Leukocyte Biology 2020 Vol. 107 Issue 6 Pages 1155-1166 DOI: 10.1002/JLB.2MA1119-300R
  114. Actin-tropomyosin distribution in non-muscle cells D. J. Manstein, J. C. M. Meiring, E. C. Hardeman and P. W. Gunning Journal of Muscle Research and Cell Motility 2020 Vol. 41 Issue 1 Pages 11-22 DOI: 10.1007/s10974-019-09514-0
  115. Seropositivity for pathogens associated with chronic infections is a risk factor for all-cause mortality in the elderly: findings from the Memory and Morbidity in Augsburg Elderly (MEMO) Study M. Zeeb, T. Kerrinnes, L. Cicin-Sain, C. A. Guzman, W. Puppe, T. F. Schulz, et al.GeroScience 2020 Vol. 42 Issue 5 Pages 1365-1376DOI: 10.1007/s11357-020-00216-x
  1. Identification of Cerebrospinal Fluid Metabolites as Biomarkers for Enterovirus Meningitis.Ratuszny D, Sühs KW, Novoselova N, Kuhn M, Kaever V, Skripuletz T, Pessler F, Stangel M.  Int J Mol Sci. 2019 Jan 15;20(2):337.
  2. Reply to: „Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation“. Borst K, Graalmann T, Kalinke U. J Hepatol. 2019 Apr;70(4):815-816. Epub 2019 Feb 1.
  3. The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity. Seidel MG, Kindle G, Gathmann B, Quinti I, Buckland M, van Montfrans J, Scheible R, Rusch S, Gasteiger LM, Grimbacher B, Mahlaoui N, Ehl S; ESID Registry Working Party and collaborators. J Allergy Clin Immunol Pract. 2019 Jul – Aug;7(6):1763-1770. Epub 2019 Feb 15.
  4. Microbiome Dependent Regulation of Tregs and Th17 Cells in Mucosa. Pandiyan P, Bhaskaran N, Zou M, Schneider E, Jayaraman S, Huehn J.
    Front Immunol. 2019 Mar 8;10:426. eCollection 2019. Review.
  5. Progressive Immunodeficiency with Gradual Depletion of B and CD4⁺ T Cells in Immunodeficiency, Centromeric Instability and Facial Anomalies Syndrome 2 (ICF2). Sogkas G, Dubrowinskaja N, Bergmann AK, Lentes J, Ripperger T, Fedchenko M, Ernst D, Jablonka A, Geffers R, Baumann U, Schmidt RE, Atschekzei F. Diseases. 2019 Apr 4;7(2):34.
  6. Cytomegalovirus memory inflation and immune protection. Cicin-Sain L. Med Microbiol Immunol. 2019 Aug;208(3-4):339-347. Epub 2019 Apr 10. Review.
  7. Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency. Eskandarian Z, Fliegauf M, Bulashevska A, Proietti M, Hague R, Smulski CR, Schubert D, Warnatz K, Grimbacher B. Front Immunol. 2019 Apr 16;10:568. eCollection 2019. Erratum in: Front Immunol. 2019 Jun 28;10:1490.
  8. Corrigendum: Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency. Eskandarian Z, Fliegauf M, Bulashevska A, Proietti M, Hague R, Smulski CR, Schubert D, Warnatz K, Grimbacher B. Front Immunol. 2019 Jun 28;10:1490. eCollection 2019.
  9. Evaluating laboratory criteria for combined immunodeficiency in adult patients diagnosed with common variable immunodeficiency. von Spee-Mayer C, Koemm V, Wehr C, Goldacker S, Kindle G, Bulashevska A, Proietti M, Grimbacher B, Ehl S, Warnatz K. Clin Immunol. 2019 Jun;203:59-62. Epub 2019 Apr 17.
  10. Actin-tropomyosin distribution in non-muscle cells. Manstein DJ, Meiring JCM, Hardeman EC, Gunning PW. J Muscle Res Cell Motil. 2019 May 4.
  11. Distinct Surface Expression of Activating Receptor Ly49H Drives Differential Expansion of NK Cell Clones upon Murine Cytomegalovirus Infection. Grassmann S, Pachmayr LO, Leube J, Mihatsch L, Andrae I, Flommersfeld S, Oduro J, Cicin-Sain L, Schiemann M, Flossdorf M, Buchholz VR. Immunity. 2019 Jun 18;50(6):1391-1400.e4. Epub 2019 May 15.
  12. IL-1β Promotes Staphylococcus aureus Biofilms on Implants in vivo. Gutierrez Jauregui R, Fleige H, Bubke A, Rohde M, Weiss S, Förster R. Front Immunol. 2019 May 17;10:1082. eCollection 2019.
  13. Chemokines and other mediators in the development and functional organization of lymph nodes. Eckert N, Permanyer M, Yu K, Werth K, Förster R. Immunol Rev. 2019 May;289(1):62-83. Review.
  14. Diversity patterns of bacteriophages infecting Aggregatibacter and Haemophilus species across clades and niches. Szafrański SP, Kilian M, Yang I, Bei der Wieden G, Winkel A, Hegermann J, Stiesch M. ISME J. 2019 Oct;13(10):2500-2522. Epub 2019 Jun 14.
  15. Life-long control of cytomegalovirus (CMV) by T resident memory cells in the adipose tissue results in inflammation and hyperglycemia. Contreras NA, Sitnik KM, Jeftic I, Coplen CP, Čičin-Šain L, Nikolich-Žugich J. PLoS Pathog. 2019 Jun 20;15(6):e1007890.
  16. STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus. Tegtmeyer PK, Spanier J, Borst K, Becker J, Riedl A, Hirche C, Ghita L, Skerra J, Baumann K, Lienenklaus S, Doering M, Ruzsics Z, Kalinke U. Nat Commun. 2019 Jun 27;10(1):2830.
  17. Constitutive TNF-α signaling in neonates is essential for the development of tissue-resident leukocyte profiles at barrier sites. Bickes MS, Pirr S, Heinemann AS, Fehlhaber B, Halle S, Völlger L, Willers M, Richter M, Böhne C, Albrecht M, Langer M, Pfeifer S, Jonigk D, Vieten G, Ure B, von Kaisenberg C, Förster R, von Köckritz-Blickwede M, Hansen G, Viemann D. FASEB J. 2019 Oct;33(10):10633-10647. Epub 2019 Jun 29.
  18. The German National Registry of Primary Immunodeficiencies (2012-2017). El-Helou SM, Biegner AK, Bode S, Ehl SR, Heeg M, Maccari ME, Ritterbusch H, Speckmann C, Rusch S, Scheible R, Warnatz K, Atschekzei F, Beider R, Ernst D, Gerschmann S, Jablonka A, Mielke G, Schmidt RE, Schürmann G, Sogkas G, Baumann UH, Klemann C, Viemann D, von Bernuth H, Krüger R, Hanitsch LG, Scheibenbogen CM, Wittke K, Albert MH, Eichinger A, Hauck F, Klein C, Rack-Hoch A, Sollinger FM, Avila A, Borte M, Borte S, Fasshauer M, Hauenherm A, Kellner N, Müller AH, Ülzen A, Bader P, Bakhtiar S, Lee JY, Heß U, Schubert R, Wölke S, Zielen S, Ghosh S, Laws HJ, Neubert J, Oommen PT, Hönig M, Schulz A, Steinmann S, Schwarz K, Dückers G, Lamers B, Langemeyer V, Niehues T, Shai S, Graf D, Müglich C, Schmalzing MT, Schwaneck EC, Tony HP, Dirks J, Haase G, Liese JG, Morbach H, Foell D, Hellige A, Wittkowski H, Masjosthusmann K, Mohr M, Geberzahn L, Hedrich CM, Müller C, Rösen-Wolff A, Roesler J, Zimmermann A, Behrends U, Rieber N, Schauer U, Handgretinger R, Holzer U, Henes J, Kanz L, Boesecke C, Rockstroh JK, Schwarze-Zander C, Wasmuth JC, Dilloo D, Hülsmann B, Schönberger S, Schreiber S, Zeuner R, Ankermann T, von Bismarck P, Huppertz HI, Kaiser-Labusch P, Greil J, Jakoby D, Kulozik AE, Metzler M, Naumann-Bartsch N, Sobik B, Graf N, Heine S, Kobbe R, Lehmberg K, Müller I, Herrmann F, Horneff G, Klein A, Peitz J, Schmidt N, Bielack S, Groß-Wieltsch U, Classen CF, Klasen J, Deutz P, Kamitz D, Lassay L, Tenbrock K, Wagner N, Bernbeck B, Brummel B, Lara-Villacanas E, Münstermann E, Schneider DT, Tietsch N, Westkemper M, Weiß M, Kramm C, Kühnle I, Kullmann S, Girschick H, Specker C, Vinnemeier-Laubenthal E, Haenicke H, Schulz C, Schweigerer L, Müller TG, Stiefel M, Belohradsky BH, Soetedjo V, Kindle G, Grimbacher B. Front Immunol. 2019 Jul 19;10:1272. eCollection 2019.
  19. Diversity of Bacteria Exhibiting Bile Acid-inducible 7alpha-dehydroxylation Genes in the Human Gut. Vital M, Rud T, Rath S, Pieper DH, Schlüter D. Comput Struct Biotechnol J 2019;17:1016-1019
  20. Preferential uptake of chitosan-coated PLGA nanoparticles by primary human antigen presenting cells. Durán V, Yasar H, Becker J, Thiyagarajan D, Loretz B, Kalinke U, Lehr CM. Nanomedicine. 2019 Oct;21:102073. Epub 2019 Jul 31.
  21. Emerging therapies against infections with Pseudomonas aeruginosa. Tümmler B. F1000Res. 2019 Aug 7;8. pii: F1000 Faculty Rev-1371. eCollection 2019. Review.
  22. Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy. Soon CF, Zhang S, Suneetha PV, Antunes DA, Manns MP, Raha S, Schultze-Florey C, Prinz I, Wedemeyer H, Sällberg Chen M, Cornberg M. Front Immunol. 2019 Sep 4;10:2076. eCollection 2019.
  23. Tau-protein concentrations are not elevated in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. Möhn N, Luo Y, Skripuletz T, Schwenkenbecher P, Zerr I, Lange P, Stangel M.  Fluids Barriers CNS. 2019 Sep 5;16(1):28.
  24. Injection of Antibodies against Immunodominant Epitopes Tunes Germinal Centers to Generate Broadly Neutralizing Antibodies. Meyer-Hermann M. Cell Rep. 2019 Oct 29;29(5):1066-1073.e5.
  25. The role of Ames dwarfism and calorie restriction on gut microbiota. Wiesenborn DS, Gálvez EJC, Spinel L, Victoria B, Allen B, Schneider A, Gesing A, Al-Regaiey KA, Strowig T, Schäfer KH, Masternak MM. J Gerontol A Biol Sci Med Sci. 2019 Oct 30.
  26. The Antimicrobial and Immunomodulatory Function of RNase 7 in Skin. Rademacher F, Dreyer S, Kopfnagel V, Gläser R, Werfel T, Harder J. Front Immunol. 2019 Nov 5;10:2553.  eCollection 2019. Review.
  27. Interleukin-17 cytokines: Effectors and targets in psoriasis-A breakthrough in understanding and treatment. Prinz I, Sandrock I, Mrowietz U. J Exp Med. 2020 Jan 6;217(1):e20191397, epub 2019_11_14
  28. Late-Onset Antibody Deficiency Due to Monoallelic Alterations in NFKB1. Schröder C, Sogkas G, Fliegauf M, Dörk T, Liu D, Hanitsch LG, Steiner S, Scheibenbogen C, Jacobs R, Grimbacher B, Schmidt RE, Atschekzei F. Front Immunol. 2019 Nov 14;10:2618. eCollection 2019.
  29. Recurrent Eczema Herpeticum – A Retrospective European Multicenter Study Evaluating the Clinical Characteristics of Eczema Herpeticum Cases in Atopic Dermatitis Patients. Seegräber M, Worm M, Werfel T, Svensson A, Novak N, Simon D, Darsow U, Augustin M, Wollenberg A. J Eur Acad Dermatol Venereol 2020;34(5):1074-1079
  30. The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens. Zhou N, Jiang Y, Bergquist TR, Lee AJ, Kacsoh BZ, Crocker AW, Lewis KA, Georghiou G, Nguyen HN, Hamid MN, Davis L, Dogan T, Atalay V, Rifaioglu AS, Dalkıran A, Cetin Atalay R, Zhang C, Hurto RL, Freddolino PL, Zhang Y, Bhat P, Supek F, Fernández JM, Gemovic B, Perovic VR, Davidović RS, Sumonja N, Veljkovic N, Asgari E, Mofrad MRK, Profiti G, Savojardo C, Martelli PL, Casadio R, Boecker F, Schoof H, Kahanda I, Thurlby N, McHardy AC, Renaux A, Saidi R, Gough J, Freitas AA, Antczak M, Fabris F, Wass MN, Hou J, Cheng J, Wang Z, Romero AE, Paccanaro A, Yang H, Goldberg T, Zhao C, Holm L, Törönen P, Medlar AJ, Zosa E, Borukhov I, Novikov I, Wilkins A, Lichtarge O, Chi PH, Tseng WC, Linial M, Rose PW, Dessimoz C, Vidulin V, Dzeroski S, Sillitoe I, Das S, Lees JG, Jones DT, Wan C, Cozzetto D, Fa R, Torres M, Warwick Vesztrocy A, Rodriguez JM, Tress ML, Frasca M, Notaro M, Grossi G, Petrini A, Re M, Valentini G, Mesiti M, Roche DB, Reeb J, Ritchie DW, Aridhi S, Alborzi SZ, Devignes MD, Koo DCE, Bonneau R, Gligorijević V, Barot M, Fang H, Toppo S, Lavezzo E, Falda M, Berselli M, Tosatto SCE, Carraro M, Piovesan D, Ur Rehman H, Mao Q, Zhang S, Vucetic S, Black GS, Jo D, Suh E, Dayton JB, Larsen DJ, Omdahl AR, McGuffin LJ, Brackenridge DA, Babbitt PC, Yunes JM, Fontana P, Zhang F, Zhu S, You R, Zhang Z, Dai S, Yao S, Tian W, Cao R, Chandler C, Amezola M, Johnson D, Chang JM, Liao WH, Liu YW, Pascarelli S, Frank Y, Hoehndorf R, Kulmanov M, Boudellioua I, Politano G, Di Carlo S, Benso A, Hakala K, Ginter F, Mehryary F, Kaewphan S, Björne J, Moen H, Tolvanen MEE, Salakoski T, Kihara D, Jain A, Šmuc T, Altenhoff A, Ben-Hur A, Rost B, Brenner SE, Orengo CA, Jeffery CJ, Bosco G, Hogan DA, Martin MJ, O’Donovan C, Mooney SD, Greene CS, Radivojac P, Friedberg I. Genome Biol. 2019 Nov 19;20(1):244.
  31. Distinct molecular response patterns of activating STAT3 mutations associate with penetrance of lymphoproliferation and autoimmunity. Jägle S, Heeg M, Grün S, Rensing-Ehl A, Maccari ME, Klemann C, Jones N, Lehmberg K, Bettoni C, Warnatz K, Grimbacher B, Biebl A, Schauer U, Hague R, Neth O, Mauracher A, Pachlopnik Schmid J, Fabre A, Kostyuchenko L, Führer M, Lorenz MR, Schwarz K, Rohr J, Ehl S. Clin Immunol. 2019 Nov 23;210:108316.
  32. The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies. Jandus P, Boligan KF, Smith DF, de Graauw E, Grimbacher B, Jandus C, Abdelhafez MM, Despont A, Bovin N, Simon D, Rieben R, Simon HU, Cummings RD, von Gunten S. Blood. 2019 Nov 28;134(22):1941-1950.
  33. PedCAPNETZ – prospective observational study on community acquired pneumonia in children and adolescents. Wetzke M, Kopp MV, Seidenberg J, Vogelberg C, Ankermann T, Happle C, Voigt G, Köster H, Illig T, Lex C, Schuster A, Panning M, Barten G, Rohde G, Welte T, Hansen G; pedCAPNETZ Study Group. BMC Pulm Med. 2019 Dec 9;19(1):238.
  34. Structural Noninfectious Manifestations of the Central Nervous System in Common Variable Immunodeficiency Disorders. van de Ven A, Mader I, Wolff D, Goldacker S, Fuhrer H, Rauer S, Grimbacher B, Warnatz K. J Allergy Clin Immunol Pract. 2019 Dec 16. pii: S2213-2198(19)31026-8.
  35. B cell hyperactivation in an Ackr4-deficient mouse strain is not caused by lack of ACKR4 expression. Eckert N, Werth K, Willenzon S, Tan L, Förster R. J Leukoc Biol. 2019 Dec 16.
  36. Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score Tesch VK, Abolhassani H, Shadur B, Zobel J, Mareika Y, Sharapova S, Karakoc-Aydiner E, Rivière JG, Garcia-Prat M, Moes N, Haerynck F, Gonzales-Granado LI, Santos Pérez JL, Mukhina A, Shcherbina A, Aghamohammadi A, Hammarström L, Dogu F, Haskologlu S, İkincioğulları AI, Köstel Bal S, Baris S, Kilic SS, Karaca NE, Kutukculer N, Girschick H, Kolios A, Keles S, Uygun V, Stepensky P, Worth A, van Montfrans JM, Peters AMJ, Meyts I, Adeli M, Marzollo A, Padem N, Khojah AM, Chavoshzadeh Z, Avbelj Stefanija M, Bakhtiar S, Florkin B, Meeths M, Gamez L, Grimbacher B, Seppänen MRJ, Lankester A, Gennery AR, Seidel MG; J Allergy Clin Immunol 2020 May;145(5):1452-1463. Epub 2019 Dec 27.
  37. Targeting the Kaposi Sarcoma Herpesvirus ORF 21 tyrosine kinase and viral lytic reactivation by tyrosine kinase inhibitors approved for clinical use. Beauclair G, Naimo E, Dubich T, Rückert J, Koch S, Dhingra A, Wirth D, Schulz TF. J Virol. 2019 Dec 11. pii: JVI.01791-19. doi: 10.1128/JVI.01791-19. [Epub ahead of print]
  38. Control of Nipah Virus Infection in Mice by the Host Adaptors Mitochondrial Antiviral Signaling Protein (MAVS) and Myeloid Differentiation Primary Response 88 (MyD88). Iampietro M, Aurine N, Dhondt KP, Dumont C, Pelissier R, Spanier J, Vallve A, Raoul H, Kalinke U, Horvat B. J Infect Dis. 2020 May 11;221(Suppl 4):S401-S406. Dec 19
  39. RNA-Based Adjuvants: Immunoenhancing Effect on Antiviral Vaccines and Regulatory Considerations. Ziegler A, Hinz T, Kalinke U. Crit Rev Immunol. 2019;39(1):1-14.
  40. Update of the statements on biology and clinical impact of occult hepatitis B virus infection. Raimondo G, Locarnini S, Pollicino T, Levrero M, Zoulim F, Lok AS; Taormina Workshop on Occult HBV Infection Faculty Members.  J Hepatol. 2019 Aug;71(2):397-408. doi: 10.1016/j.jhep.2019.03.034. Epub 2019 Apr 18. PMID: 31004683.
  41. Synthesis of 4’/5′-Spirocyclopropanated Uridine and d-Xylouridine Derivatives and Their Activity against the Human Respiratory Syncytial Virus. Köllmann C, Wiechert SM, Jones PG, Pietschmann T, Werz DB. Org Lett. 2019 Sep 6;21(17):6966-6971. doi: 10.1021/acs.orglett.9b02555. Epub 2019 Aug 21. PMID: 31433193.
  42. Quantitative Microscopy Reveals Stepwise Alteration of Chromatin Structure during Herpesvirus Infection. Aho V, Mäntylä E, Ekman A, Hakanen S, Mattola S, Chen JH, Weinhardt V, Ruokolainen V, Sodeik B, Larabell C, Vihinen-Ranta M. Viruses. 2019 Oct 11;11(10):935. doi: 10.3390/v11100935. PMID: 31614678; PMCID: PMC6832731.
  43. Probabilistic variable-length segmentation of protein sequences for discriminative motif discovery (DiMotif) and sequence embedding (ProtVecX). Asgari E, McHardy AC, Mofrad MRK. Sci Rep. 2019 Mar 5;9(1):3577. doi: 10.1038/s41598-019-38746-w. PMID: 30837494; PMCID: PMC6401088.
  44. Keratinized mucosa width is associated with severity of peri-implant mucositis. A cross-sectional study. Jasmin Grischke, Annika Karch, Andreas Wenzlaff, Magdalena Marta Foitzik, Meike Stiesch, Jörg Eberhard. Clinical Oral Implants Research. First published: 10 April 2019. https://doi.org/10.1111/clr.13432
  45. Impaired cellular energy metabolism in cord blood macrophages contributes to abortive response toward inflammatory threats. Dreschers S, Ohl K, Lehrke M, Möllmann J, Denecke B, Costa I, Vogl T, Viemann D, Roth J, Orlikowsky T, Tenbrock K. Nat Commun. 2019 Apr 11;10(1):1685. doi: 10.1038/s41467-019-09359-8. PMID: 30976008; PMCID: PMC6459909.
  46. HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0. J Neuroinflammation. Hensel N, Raker V, Förthmann B, Detering NT, Kubinski S, Buch A, Katzilieris-Petras G, Spanier J, Gudi V, Wagenknecht S, Kopfnagel V, Werfel TA, Stangel M, Beineke A, Kalinke U, Paludan SR, Sodeik B, Claus P. 2019 Dec 2;16(1):248. doi: 10.1186/s12974-019-1647-5. PMID: 31791351; PMCID: PMC6889453.
  47. Hepatitis D Virus-Specific CD8+ T Cells Have a Memory-Like Phenotype Associated With Viral Immune Escape in Patients With Chronic Hepatitis D Virus Infection. Kefalakes H, Koh C, Sidney J, Amanakis G, Sette A, Heller T, Rehermann B.  Gastroenterology. 2019 May;156(6):1805-1819.e9. doi: 10.1053/j.gastro.2019.01.035. Epub 2019 Jan 18. PMID: 30664876; PMCID: PMC7367679.
  48. Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung. Kordes A, Preusse M, Willger SD, Braubach P, Jonigk D, Haverich A, Warnecke G, Häussler S.  Nat Commun. 2019 Jul 30;10(1):3397. doi: 10.1038/s41467-019-11414-3. PMID: 31363089; PMCID: PMC6667473.
  49. Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 Philine Kirsch, Valentin Jakob, +4 authors M. Empting. Journal of Medicinal Chemistry. 19 March 2019 DOI:10.1021/acs.jmedchem.8b01827Corpus ID: 84183173
  50. Establishment of an induced memory response in Pseudomonas aeruginosa during infection of a eukaryotic host. Kordes A, Grahl N, Koska M, Preusse M, Arce-Rodriguez A, Abraham WR, Kaever V, Häussler S. ISME J. 2019 Aug;13(8):2018-2030. doi: 10.1038/s41396-019-0412-1. Epub 2019 Apr 5. PMID: 30952997; PMCID: PMC6775985.
  51. Diversity of Bacteria Exhibiting Bile Acid-inducible 7α-dehydroxylation Genes in the Human Gut. Vital M, Rud T, Rath S, Pieper DH, Schlüter D.  Comput Struct Biotechnol J. 2019 Jul 26;17:1016-1019. doi: 10.1016/j.csbj.2019.07.012. PMID: 31428294; PMCID: PMC6692061.
  52. Cohort profile: The LoewenKIDS Study – life-course perspective on infections, the microbiome and the development of the immune system in early childhood. Gottschick C, Raupach-Rosin H, Langer S, Hassan L, Horn J, Dorendorf E, Caputo M, Bittner M, Beier L, Rübsamen N, Schlinkmann K, Zoch B, Guzman CA, Hansen G, Heselich V, Holzapfel E, Hübner J, Pietschmann T, Pieper DH, Pletz M, Riese P, Schmidt-Pokrzywniak A, Hartwig S, von Kaisenberg C, Aydogdu M, Buhles M, Dressler F, Eberl W, Haase R, von Koch FE, Feidicker S, Frambach T, Franz HGB, Guthmann F, Koch HG, Seeger S, Oberhoff C, Pauker W, Petry KU, Schild RL, Tchirikov M, Röhrig E, Karch A, Mikolajczyk R. Int J Epidemiol. 2019 Aug 1;48(4):1382-1383. doi: 10.1093/ije/dyz069. Erratum for: Int J Epidemiol. 2019 Aug 1;48(4):1042-1043h. PMID: 30938437; PMCID: PMC7263872.
  53. Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2. Klemann C, Camacho-Ordonez N, Yang L, Eskandarian Z, Rojas-Restrepo JL, Frede N, Bulashevska A, Heeg M, Al-Ddafari MS, Premm J, Seidl M, Ammann S, Sherkat R, Radhakrishnan N, Warnatz K, Unger S, Kobbe R, Hüfner A, Leahy TR, Ip W, Burns SO, Fliegauf M, Grimbacher B. Front Immunol. 2019 Mar 19;10:297. doi: 10.3389/fimmu.2019.00297. PMID: 30941118; PMCID: PMC6435015.
  54. Autophagic degradation of lamins facilitates the nuclear egress of herpes simplex virus type 1. Turan A, Grosche L, Krawczyk A, Mühl-Zürbes P, Drassner C, Düthorn A, Kummer M, Hasenberg M, Voortmann S, Jastrow H, Dörrie J, Schaft N, Kraner M, Döhner K, Sodeik B, Steinkasserer A, Heilingloh CS. J Cell Biol. 2019 Feb 4;218(2):508-523. doi: 10.1083/jcb.201801151. Epub 2018 Dec 26. PMID: 30587512; PMCID: PMC6363456.
  55. Kynurenine Is a Cerebrospinal Fluid Biomarker for Bacterial and Viral Central Nervous System Infections Sühs KW, Novoselova N, Kuhn M, Seegers L, Kaever V, Müller-Vahl K, Trebst C, Skripuletz T, Stangel M, Pessler F.  J Infect Dis. 2019 Jun 5;220(1):127-138.
  56. HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0 Hensel N, Raker V, Förthmann B, Detering NT, Kubinski S, Buch A, Katzilieris-Petras G, Spanier J, Gudi V, Wagenknecht S, Kopfnagel V, Werfel TA, Stangel M, Beineke A, Kalinke U, Paludan SR, Sodeik B, Claus P.  J Neuroinflammation 2019;16(1):248
  57. Kynurenine Is a Cerebrospinal Fluid Biomarker for Bacterial and Viral Central Nervous System Infections K. W. Sühs, N. Novoselova, M. Kuhn, L. Seegers, V. Kaever, K. Müller-Vahl, et al. J Infect Dis 2019 Vol. 220 Issue 1 Pages 127-138 Accession Number: 30721966 DOI: 10.1093/infdis/jiz048

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