Prof. Dr. Till Strowig participates in RESIST research projects B1 and B2.
| My Research Interest in RESIST |
Our research focus in RESIST is the identification and validation of the role of the gastrointestinal microbiome in infections and inflammatory conditions affecting susceptible and immunocompromised individuals. Therefore, we are employing sequencing-based, microbiological and immunological approaches applying them to gnotobiotic animal models and patient cohorts in collaboration with other RESIST scientists. The long-term aim is to identify pathophysiological conditions, which could be improved by targeting the microbiome therapeutically.
Prof. Strowig about his scientific work
Prof. Dr. Till Strowig – Curriculum Vitae
Current Position
Undergraduate and Postgraduate Training
Academic and Research Posts
Other Scientific Roles
10 Selected Publications
Osbelt L, Almási E, Wende M, Kienesberger S, Voltz A, Lesker TR, Muthukumarasamy U, Knischewski N, Nordmann E, Bielecka AA, Giralt-Zúñiga M, Kaganovitch E, Kühne C, Baier C, Pietsch M, Müsken M, Greweling-Pils MC, Breinbauer R, Flieger A, Schlüter D, Müller R, Erhardt M, Zechner EL, Strowig T. Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms. Nat Microbiol. in press.
Huang KD, Amend L, Gálvez EJC, Lesker TR, de Oliveira R, Bielecka AA, Blanco-Míguez A, Valles-Colomer M, Ruf I, Pasolli E, Buer J, Segata N, Esser S, Strowig T*, Kehrmann J*. Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices. Cell Rep Med. 2024 Mar 19;5(3):101426. DOI: 10.1016/j.xcrm.2024.101426. Open Access
Blanco-Míguez A, Gálvez EJC, Pasolli E, De Filippis F, Amend L, Huang KD, Manghi P, Lesker TR, Riedel T, Cova L, Punčochář M, Thomas AM, Valles-Colomer M, Schober I, Hitch TCA, Clavel T, Berry SE, Davies R, Wolf J, Spector TD, Overmann J, Tett A, Ercolini D, Segata N*, Strowig T*. Extension of the Segatella copri complex to 13 species with distinct large extrachromosomal elements and associations with host conditions. Cell Host Microbe. 2023; Nov 8;31(11):1804-1819e9. DOI: 10.1016/j.chom.2023.09.013. Open Access
Bublitz A, Brauer M, Wagner S, Hofer W, Müsken M, Deschner F, Lesker TR, Neumann-Schaal M, Paul LS, Nübel U, Bartel J, Kany AM, Zühlke D, Bernecker S, Jansen R, Sievers S, Riedel K, Herrmann J, Müller R, Fuchs TM*, Strowig T*. The natural product chlorotonil A preserves colonization resistance and prevents relapsing Clostridioides difficile infection. Cell Host Microbe. 2023; May 10;31(5):734-750. DOI: 10.1016/j.chom.2023.04.003. Open Access
Li J, Galvez EJC, Amend L, Almási E, Iljazovic A, Lesker TR, Bielecka AA, Schorr EM, Strowig, T. A versatile genetic toolbox for Prevotella copri enables studying polysaccharide utilization systems. EMBO J. 2021; 40(23). DOI: 10.15252/embj.2021108287. Open Access
Osbelt L, Wende M, Almási E, Derksen E, Muthukumarasamy U, Lesker TR, Galvez EJC, Pils MC, Schalk E, Chhatwal P, Färber J, Neumann-Schaal M, Fischer T, Schlüter D, Strowig T. Klebsiella oxytoca causes colonization resistance against multidrug-resistant Klebsiella pneumoniae in the gut via cooperative carbohydrate competition. Cell Host & Microbe. 2021; 29(11), 1663-1679. DOI: 10.1016/j.chom.2021.09.003. Open Access
Gálvez EJC, Iljazovic A, Amend L, Lesker TR, Renault T, Thiemann S, Hao L, Roy U, Gronow A, Charpentier E, Strowig T. Distinct polysaccharide utilization as determinants for interspecies competition between intestinal Prevotella spp. Cell Host & Microbe. 2020; 28(6), 838-852. DOI: 10.1016/j.chom.2020.09.012. Open Access
Iljazovic A, Roy U, Gálvez EJC, Lesker TR, Zhao B, Gronow A, Amend L, Will SE, Hofmann JD, Pils MC, Schmidt-Hohagen K, Neumann-Schaal M, Strowig T. Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation. Mucosal Immunol. 2020; 14(1), 113-124. DOI: 10.1038/s41385-020-0296-4. Open Access
Lesker TR, Durairaj AC, Gálvez EJC, Lagkouvardos I, Baines JF, Clavel T, Sczyrba A, McHardy AC, Strowig T. 2020. An Integrated Metagenome Catalog Reveals New Insights into the Murine Gut Microbiome. Cell Rep DOI: 10.1016/j.celrep.2020.02.036. Open Access
Thiemann S, Smit N, Roy U, Lesker TR, Galvez EJC, Helmecke J, Basic M, Bleich A, Goodman AL, Kalinke U, Flavell RA, Erhardt M, Strowig T. Enhancement of IFNγ production by distinct commensals ameliorates Salmonella-induced disease. Cell Host & Microbe. 2017; 21(6), 682-694. DOI: 10.1016/j.chom.2017.05.005. Open Access
