PD Dr. Anke Kraft participates in research project B8.

My Research Interest in RESIST

Our research focus within RESIST is to understand the heterogeneity of virus-specific T cell responses in chronic viral infections and how to efficiently restore their responses to overcome chronicity. The long-term goal is to identify mechanisms and biomarkers that enable the prediction of cure. To achieve this, we focus on chronic infections with the hepatitis B virus (HBV). We study the immune responses of patients in the different phases of chronic HBV infection as well as of patients with controlled interruption of HBV antiviral therapy with nucleoside or nucleotide analogues.

In pursuing this research goal, we build on our experience in studying exhausted T cell responses. We have worked over the last two decades on the characterization and immunomodulation of immune responses in chronic viral infections (e.g. LCMV, MCMV and hepatitis B, C and E virus) in humans and mice.

PD Dr. Anke Kraft

PD Dr. Anke Kraft – Curriculum Vitae

Current Position

  • Group leader at the Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, MHH

Undergraduate and Postgraduate Training

  • 1994 – 2000 academic studies of biology, Technical University Carola-Wilhelmina Braunschweig, Germany and Georg-August-University G√∂ttingen, Germany

  • 2000-2003 PhD thesis (Dr.rer.nat.; supervisor Prof. Dr. Ulf Dittmer, University of W√ľrzburg, Germany)

  • 2018: ‚ÄėHabilitation‚Äô and award of the Venia legendi for „Experimental Medicine“ at Medical School Hannover, Title: ‚Development of new concepts for immunotherapy against viral infections‚Äô

Academic and Research Posts

  • 2003 ‚Äď 2006: Post-Doc, University of Essen, Germany

  • 2006 – 2010: Post-Doc, University of Massachusetts Medical School, Worcester, USA

  • 2010 – 2013: Independent Junior Research Group University of Essen-Duisburg, Germany

  • 2013 – 2018: Senior scientist and head of the research laboratory, AG Prof. Dr. Heiner Wedemeyer/ PD Dr. Markus Cornberg, Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School

  • Since 2018: Group leader together with Prof. Markus Cornberg ‚ÄėImmunology of Viral Hepatitis and Infections in Liver Cirrhosis‚Äô, Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School

Other Scientific Roles

  • Since 2010 Member of the German Society for Virology (GfV, Germany)

  • 2015-17/ 2019-24 Member of the German Association for the Study of the Liver (GASL, Germany)

  • 2017-2018 Member of the review committee Dr.rer.nat. at Medical School Hannover, Germany

  • Since 2019 Member of the review committee M.Sc. Biomedizin at Medical School Hannover, Germany

  • Since 2022 Member of the German Society for Immunology (DGFI, Germany)

Recommended Links

For further information about PD Dr. Krafts’s scientific work please check the following links:

10 Selected Publications

Contact

  PD Dr. Anke Kraft
   Hannover Medical School
Dept. of Gastroenterology, Hepatology, Infektionology and Endokrinologie
  Carl-Neuberg-Str. 1
30625 Hannover
  +49 511 532 Р7211
  kraft.anke@
mh-hannover.de