Dr. Berislav Bošnjak
| My Research Interest in RESIST |
The initiation of T cell immune responses by dendritic cells lies in the center of protection from pathogens but also for the induction of allergic diseases. My research focus is the differences between antiviral and allergic T-cell response initiation. Moreover, I am interested in studying the interaction of those responses in vulnerable population groups, such as people with chronic infections or asthmaics. I have joined the RESIST as an associated investigator to contribute to the research on the T cell responses in human cytomegalovirus infections.
Dr. Berislav Bošnjak in the lab
Dr. Berislav Bošnjak – Curriculum Vitae
Current Position
Undergraduate and Postgraduate Training
Academic and Research Posts
Other Scientific Roles
Awards and Prizes
10 Selected Publications (out of 55); Shared first (**) and senior (*) authorships
Bošnjak B**, Henze E**, Lueder Y, Do KTH, Rezalotfi A, Čuvalo B, Ritter C, Schimrock A, Willenzon S, Georgiev H, Fritz L, Galla M, Wagner K, Messerle M, Förster R. MCK2-mediated MCMV infection of macrophages and virus dissemination to the salivary gland depends on MHC class I molecules. Cell Rep. 2023 Jun 7;42(6):112597. doi: 10.1016/j.celrep.2023.112597. Epub ahead of print. PMID: 37289588.
Barros-Martins J**, Hammerschmidt SI**, Cossmann A**, Odak I, Stankov MV, Morillas Ramos G, Dopfer-Jablonka A, Heidemann A, Ritter C, Friedrichsen M, Schultze-Florey C, Ravens I, Willenzon S, Bubke A, Ristenpart J, Janssen A, Ssebyatika G, Bernhardt G, Münch J, Hoffmann M, Pöhlmann S, Krey T, Bošnjak B*, Förster R*, Behrens GMN*. Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination. Nat Med. 2021 Sep;27(9):1525-1529. doi: 10.1038/s41591-021-01449-9.
Bošnjak B, Stein SC, Willenzon S, Cordes AK, Puppe W, Bernhardt G, Ravens I, Ritter C, Schultze-Florey CR, Gödecke N, Martens J, Kleine-Weber H, Hoffmann M, Cossmann A, Yilmaz M, Pink I, Hoeper MM, Behrens GMN, Pöhlmann S, Blasczyk R, Schulz TF, Förster R. Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods. Cell Mol Immunol. 2021 Apr;18(4):936-944. doi: 10.1038/s41423-020-00573-9.
Bošnjak B**, Odak I**, Barros-Martins J**, Sandrock I**, Hammerschmidt SI, Permanyer M, Patzer GE, Greorgiev H, Gutierrez Jauregui R, Tscherne A, Schwarz JH, Kalodimou G, Ssebyatika G, Ciurkiewicz M, Willenzon S, Bubke A, Ristenpart J, Ritter C, Tuchel T, Meyer Zu Natrup C, Shin DL, Clever S, Limpinsel L, Baumgärtner W, Krey T, Volz A, Sutter G, Förster R. Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents. Front Immunol. 2021 Nov 11;12:772240. doi: 10.3389/fimmu.2021.772240.
Durán V**, Grabski E**, Hozsa C, Becker J, Yasar H, Monteiro JT, Costa B, Koller N, Lueder Y, Wiegmann B, Brandes G, Kaever V, Lehr CM, Lepenies B, Tampé R, Förster R, Bošnjak B*, Furch M*, Graalmann T*, Kalinke U*. Fucosylated lipid nanocarriers loaded with antibiotics efficiently inhibit mycobacterial propagation in human myeloid cells. J Control Release. 2021 Jun 10;334:201-212. doi: 10.1016/j.jconrel.2021.04.012.
Bošnjak B**, Kazemi S**, Altenburger LM, Mokrović G, Epstein MM. Th2-TRMs Maintain Life-Long Allergic Memory in Experimental Asthma in Mice. Front Immunol. 2019 Apr 24;10:840. doi: 10.3389/fimmu.2019.00840.
Hammerschmidt SI**, Werth K**, Rothe M, Galla M, Permanyer M, Patzer GE, Bubke A, Frenk DN, Selich A, Lange L, Schambach A, Bošnjak B*, Förster R*. CRISPR/Cas9 Immunoengineering of Hoxb8-Immortalized Progenitor Cells for Revealing CCR7-Mediated Dendritic Cell Signaling and Migration Mechanisms in vivo. Front Immunol. 2018 Aug 28;9:1949. doi: 10.3389/fimmu.2018.01949.
Riba M**, Garcia Manteiga JM**, Bošnjak B**, Cittaro D, Mikolka P, Le C, Epstein MM*, Stupka E*. Revealing the acute asthma ignorome: characterization and validation of uninvestigated gene networks. Sci Rep. 2016 Apr 21;6:24647. doi: 10.1038/srep24647.
Bosnjak B, Tilp C, Tomsic C, Dekan G, Pieper MP, Erb KJ, Epstein MM. Tiotropium bromide inhibits relapsing allergic asthma in BALB/c mice. Pulm Pharmacol Ther. 2014 Feb;27(1):44-51. doi: 10.1016/j.pupt.2013.09.004.
Bosnar M**, Bosnjak B**, Cuzic S, Hrvacic B, Marjanovic N, Glojnaric I, Culic O, Parnham MJ, Erakovic Haber V. Azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived granulocyte-macrophage colony-stimulating factor and interleukin-1beta. J Pharmacol Exp Ther. 2009 Oct;331(1):104-13. doi: 10.1124/jpet.109.155838.
