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81. In vitro systems to study inborn errors of immunity using human induced pluripotent stem cells. Nikolouli Eirini, Reichstein Janne, Hansen Gesine, Lachmann Nico, Frontiers in Immunology 13, 2022.
82. Tralokinumab treatment improves the skin microbiota by increasing the microbial diversity in adults with moderate-to-severe atopic dermatitis: Analysis of microbial diversity in ECZTRA 1, a randomized controlled trial. Beck LA, Bieber T, Weidinger S, Tauber M, Saeki H, Irvine AD, Eichenfield LF, Werfel T, Arlert P, Jiang L, Røpke M, Paller AS.  J Am Acad Dermatol. 2022 Dec 5
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85. Binding of Glycans to the SARS CoV-2 Spike Protein, an Open Question: NMR Data on Binding Site Localization, Affinity, and Selectivity. Maass T, Ssebyatika G, Brückner M, Breckwoldt L, Krey T, Mallagaray A, Peters T, Frank M, Creutznacher R. Chemistry. 2022 Dec 20;28(71):e202202614.Epub 2022 Oct 26.
86. Primary antibody deficiency-associated arthritis shares features with spondyloarthritis and enteropathic arthritis. Pott NM, Atschekzei F, Pott CC, Ernst D, Witte T, Sogkas G. RMD Open. 2022 Dec
87. Fibroblastic reticular cells mitigate acute GvHD via MHCII-dependent maintenance of regulatory T cells. Shaikh H, Pezoldt J, Mokhtari Z, Gamboa Vargas J, Le DD, Peña Mosca J, Arellano Viera E, Kern MA, Graf C, Beyersdorf N, Lutz MB, Riedel A, Büttner-Herold M, Zernecke A, Einsele H, Saliba AE, Ludewig B, Huehn J, Beilhack A. JCI Insight. 2022 Nov 22
88. Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA-Virus Inhibitors. Haack PA, Harmrolfs K, Bader CD, Garcia R, Gunesch AP, Haid S, Popoff A, Voltz A, Kim H, Bartenschlager R, Pietschmann T, Müller R. Angew Chem Int Ed Engl. 2022 Dec 23; Epub 2022 Nov 28.
89. Genomic epidemiology of clinical ESBL-producing Enterobacteriaceae in a German hospital suggests infections are primarily community- and regionally-acquired. Neffe L, Forde TL, Oravcova K, Köhler U, Bautsch W, Tomasch J, Häussler S.  Microb Genom. 2022 Dec;8(12):mgen000901.
90. Phenotypic spectrum in recessive STING-associated vasculopathy with onset in infancy: Four novel cases and analysis of previously reported cases. Wan R, Fänder J, Zakaraia I, Lee-Kirsch MA, Wolf C, Lucas N, Olfe LI, Hendrich C, Jonigk D, Holzinger D, Steindor M, Schmidt G, Davenport C, Klemann C, Schwerk N, Griese M, Schlegelberger B, Stehling F, Happle C, Auber B, Steinemann D, Wetzke M, von Hardenberg S. Front Immunol. 2022 Oct 6;13:1029423.
91. Copy Number Analysis in a Large Cohort Suggestive of Inborn Errors of Immunity Indicates a Wide Spectrum of Relevant Chromosomal Losses and Gains. Wan R, Schieck M, Caballero-Oteyza A, Hofmann W, Cochino AV, Shcherbina A, Sherkat R, Wache-Mainier C, Fernandez A, Sultan M, Illig T, Grimbacher B, Proietti M, Steinemann D. J Clin Immunol. 2022 Jul;42(5):1083-1092.
92. Do common infections trigger disease-onset or -severity in CTLA-4 insufficiency? Krausz M, Mitsuiki N, Falcone V, Komp J, Posadas-Cantera S, Lorenz HM, Litzman J, Wolff D, Kanariou M, Heinkele A, Speckmann C, Häcker G, Hengel H, Gámez-Díaz L, Grimbacher B. Front Immunol. 2022 Nov 2;13:1011646.
93. Allele-Specific Disruption of a Common STAT3 Autosomal Dominant Allele Is Not Sufficient to Restore Downstream Signaling in Patient-Derived T Cells. König S, Fliegauf M, Rhiel M, Grimbacher B, Cornu TI, Cathomen T, Mussolino C. Genes (Basel). 2022 Oct 20;13(10):1912.
94. Birch pollen extract enhances human cytomegalovirus replication in monocyte-derived dendritic cells. Allergy. 2023 Feb;78(2):543-546. Fneish Z, Becker J, Mulenge F, Costa B, Krajewski L, Duran V, Ziegler A, Sommer V, Traidl-Hoffmann C, Gilles S, Kalinke U. doi: 10.1111/all.15497. Epub 2022 Sep 13. PMID: 36038150.
95. COVID-19 in pediatric lung transplant recipients: Clinical course and outcome. J Heart Lung Transplant. Schütz K, Davids J, Petrik B, Zychlinsky Scharff A, Carlens J, Heim A, Salman J, Ius F, Bobylev D, Hansen G, Müller C, Schwerk N.  2023 Apr;42(4):533-538. doi: 10.1016/j.healun.2022.11.006. Epub 2022 Dec 5. PMID: 36526496; PMCID: PMC9719846.
96. A circular RNA derived from the insulin receptor locus protects against doxorubicin-induced cardiotoxicity. Lu D, Chatterjee S, Xiao K, Riedel I, Huang CK, Costa A, Cushman S, Neufeldt D, Rode L, Schmidt A, Juchem M, Leonardy J, Büchler G, Blume J, Gern OL, Kalinke U, Wen Tan WL, Foo R, Vink A, van Laake LW, van der Meer P, Bär C, Thum T.  Eur Heart J. 2022 Nov 7;43(42):4496-4511. doi: 10.1093/eurheartj/ehac337. PMID: 35758064; PMCID: PMC9637424.
97. A CMV-induced adaptive human Vδ1+ γδ T cell clone recognizes HLA-DR. Deseke M, Rampoldi F, Sandrock I, Borst E, Böning H, Ssebyatika GL, Jürgens C, Plückebaum N, Beck M, Hassan A, Tan L, Demera A, Janssen A, Steinberger P, Koenecke C, Viejo-Borbolla A, Messerle M, Krey T, Prinz I. J Exp Med. 2022 Sep 5;219(9):e20212525. doi: 10.1084/jem.20212525. Epub 2022 Jul 19. PMID: 35852466; PMCID: PMC9301659.
98. Antibacterial and Cytocompatible: Combining Silver Nitrate with Strontium Acetate Increases the Therapeutic Window. Parizi MK, Doll K, Rahim MI, Mikolai C, Winkel A, Stiesch M.  Int J Mol Sci. 2022 Jul 22;23(15):8058. doi: 10.3390/ijms23158058. PMID: 35897634; PMCID: PMC9331456.
99. Association of SARS-CoV-2 Seropositivity With Myalgic Encephalomyelitis and/or Chronic Fatigue Syndrome Among Children and Adolescents in Germany. Sorg AL, Becht S, Jank M, Armann J, von Both U, Hufnagel M, Lander F, Liese JG, Niehues T, Verjans E, Wetzke M, Stojanov S, Behrends U, Drosten C, Schroten H, von Kries R.  JAMA Netw Open. 2022 Sep 1;5(9):e2233454. doi: 10.1001/jamanetworkopen.2022.33454. PMID: 36166227; PMCID: PMC9516317.
100. Bacterial low-abundant taxa are key determinants of a healthy airway metagenome in the early years of human life. Pust MM, Tümmler B.  Comput Struct Biotechnol J. 2021 Dec 15;20:175-186. doi: 10.1016/j.csbj.2021.12.008. PMID: 35024091; PMCID: PMC8713036.
101. Bulevirtide with or without pegIFNα for patients with compensated chronic hepatitis delta: From clinical trials to real-world studies. Lampertico P, Roulot D, Wedemeyer H. J Hepatol. 2022 Nov;77(5):1422-1430. doi: 10.1016/j.jhep.2022.06.010. Epub 2022 Jun 22. PMID: 35752223.
102. Confirmation of Hyperimmunoglobulin E Syndrome in Two Patients with an Ocular Problem: Detection of Two New DOCK8 Mutations. Saghafi S, Zandieh F, Fazlollahi MR, Glocker C, Frede N, Buchta M, Yang L, Mahmoudi AH, Houshmand M, Pourpak Z, Grimbacher B, Moin M.  Iran J Allergy Asthma Immunol. 2022 Jun 18;21(3):355-363. doi: 10.18502/ijaai.v21i3.9809. PMID: 35822685.
103. Cross-sectional seroprevalence surveys of SARS-CoV-2 antibodies in children in Germany, June 2020 to May 2021. Sorg AL, Bergfeld L, Jank M, Corman V, Semmler I, Goertz A, Beyerlein A, Verjans E, Wagner N, Von Bernuth H, Lander F, Weil K, Hufnagel M, Spiekerkoetter U, Chao CM, Naehrlich L, Muntau AC, Schulze-Sturm U, Hansen G, Wetzke M, Jung AM, Niehues T, Fricke-Otto S, Von Both U, Huebner J, Behrends U, Liese JG, Schwerk C, Drosten C, Von Kries R, Schroten H.  Nat Commun. 2022 Jun 6;13(1):3128. doi: 10.1038/s41467-022-30482-6. PMID: 35668073; PMCID: PMC9170697.
104. Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50. Fliegauf M, Kinnunen M, Posadas-Cantera S, Camacho-Ordonez N, Abolhassani H, Alsina L, Atschekzei F, Bogaert DJ, Burns SO, Church JA, Dückers G, Freeman AF, Hammarström L, Hanitsch LG, Kerre T, Kobbe R, Sharapova SO, Siepermann K, Speckmann C, Steiner S, Verma N, Walter JE, Westermann-Clark E, Goldacker S, Warnatz K, Varjosalo M, Grimbacher B.  Front Immunol. 2022 Aug 29;13:965326. doi: 10.3389/fimmu.2022.965326. PMID: 36105815; PMCID: PMC9465457.
105. Entwicklungsansätze für Impfstoffe gegen Hepatitis-C-Virus-Infektionen [Development approaches for vaccines against hepatitis C virus infections]. Bankwitz D, Krey T, Pietschmann T.  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2022 Feb;65(2):183-191. German. doi: 10.1007/s00103-021-03477-9. Epub 2022 Jan 11. PMID: 35015104; PMCID: PMC8749110.
106. Distinct actin-tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes. Reindl T, Giese S, Greve JN, Reinke PY, Chizhov I, Latham SL, Mulvihill DP, Taft MH, Manstein DJ. iScience. 2022 May 30;25(7):104484. doi: 10.1016/j.isci.2022.104484. PMID: 35720262; PMCID: PMC9204724.
107. Effects of Pre-Existing Mental Conditions on Fatigue and Psychological Symptoms Post-COVID-19. Homann S, Mikuteit M, Niewolik J, Behrens GMN, Stölting A, Müller F, Schröder D, Heinemann S, Müllenmeister C, El-Sayed I, Happle C, Steffens S, Dopfer-Jablonka A. Int J Environ Res Public Health. 2022 Aug 11;19(16):9924. doi: 10.3390/ijerph19169924. PMID: 36011559; PMCID: PMC9408008.
108. Efficacy of dupilumab for the treatment of severe skin disease in cytotoxic T lymphocyte antigen-4 insufficiency: A role of type 2 inflammation? Arruda LK, Cordeiro DL, Langer SS, Koenigham-Santos M, Calado RT, Dias MM, Anhesini LR, Oliveira JB, Grimbacher B, Ferriani MPL.  J Allergy Clin Immunol Glob. 2022 Sep 22;2(1):114-117. doi: 10.1016/j.jacig.2022.08.004. PMID: 37780100; PMCID: PMC10509893.
109. Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics. Greve JN, Schwäbe FV, Pokrant T, Faix J, Di Donato N, Taft MH, Manstein DJ. Eur J Cell Biol. 2022 Apr;101(2):151216. doi: 10.1016/j.ejcb.2022.151216. Epub 2022 Mar 15. PMID: 35313204.
110. Generation of Human iPSC from Small Volume Peripheral Blood Samples. Kloos D, Lachmann N. Methods Mol Biol. 2022;2429:27-39. doi: 10.1007/978-1-0716-1979-7_3. PMID: 35507153.
111. HBcrAg Levels Are Associated With Virological Response to Treatment With Interferon in Patients With Hepatitis Delta. Sandmann L, Yurdaydin C, Deterding K, Heidrich B, Hardtke S, Lehmann P, Bremer B, Manns MP, Cornberg M, Wedemeyer H, Maasoumy B; HIDIT‐II Study Group.  Hepatol Commun. 2022 Mar;6(3):480-495. doi: 10.1002/hep4.1821. Epub 2021 Sep 24. PMID: 34561972; PMCID: PMC8870014.
112. Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells. Osanyinlusi SA, Zischke J, Jacobs R, Weissinger EM, Schulz TF, Kay-Fedorov PC. HmBio. 2022 Dec 20;13(6):e0294622. doi: 10.1128/mbio.02946-22. Epub 2022 Nov 29. PMID: 36445084; PMCID: PMC9765415.
113. It’s All in the Mix: A New Interprofessional, Blended-Learning Masters’ Program for Biomedical Data Science Addressing Physicians and Students from Life Sciences – Didactic Concept and First Experiences AuthorsMichael Marschollek, Melina Celik, Marianne Behrends, Thomas Friedrich SchulzPages56 – 60DOI10.3233/SHTI220907CategoryResearch Article Series Studies in Health Technology and Informatics Ebook Volume 298: Digital Professionalism in Health and Care: Developing the Workforce, Building the Future
114. Low Serum Cholinesterase Identifies Patients With Worse Outcome and Increased Mortality After TIPS. Stockhoff L, Muellner-Bucsics T, Markova AA, Schultalbers M, Keimburg SA, Tergast TL, Hinrichs JB, Simon N, Gerbel S, Manns MP, Mandorfer M, Cornberg M, Meyer BC, Wedemeyer H, Reiberger T, Maasoumy B. Hepatol Commun. 2022 Mar;6(3):621-632. doi: 10.1002/hep4.1829. Epub 2021 Sep 28. PMID: 34585537; PMCID: PMC8870033.
115. Lymph node stromal cells support the maturation of pre-DCs into cDC-like cells via colony-stimulating factor 1. Wiechers C, Pezoldt J, Beckstette M, Berner J, Schraml BU, Huehn J.  Immunology. 2022 Aug;166(4):475-491. doi: 10.1111/imm.13497. Epub 2022 Jun 2. PMID: 35569092.
116. Metadata harmonization-Standards are the key for a better usage of omics data for integrative microbiome analysis. Cernava T, Rybakova D, Buscot F, Clavel T, McHardy AC, Meyer F, Meyer F, Overmann J, Stecher B, Sessitsch A, Schloter M, Berg G; MicrobiomeSupport Team.  Environ Microbiome. 2022 Jun 24;17(1):33. doi: 10.1186/s40793-022-00425-1. PMID: 35751093; PMCID: PMC9233336.
117. Multi-omics analysis of naïve B cells of patients harboring the C104R mutation in TACI. Ramirez N, Posadas-Cantera S, Langer N, de Oteyza ACG, Proietti M, Keller B, Zhao F, Gernedl V, Pecoraro M, Eibel H, Warnatz K, Ballestar E, Geiger R, Bossen C, Grimbacher B. Front Immunol. 2022 Aug 16;13:938240. doi: 10.3389/fimmu.2022.938240. PMID: 36072607; PMCID: PMC9443529.
118. Nanoscale organization of the MHC I peptide-loading complex in human dendritic cells. Koller N, Höllthaler P, Barends M, Döring M, Spahn C, Durán V, Costa B, Becker J, Heilemann M, Kalinke U, Tampé R. Cell Mol Life Sci. 2022 Aug 10;79(9):477. doi: 10.1007/s00018-022-04472-2. PMID: 35947215; PMCID: PMC9365725.
119. Phenotype, genotype, treatment, and survival outcomes in patients with X-linked inhibitor of apoptosis deficiency. Yang L, Booth C, Speckmann C, Seidel MG, Worth AJJ, Kindle G, Lankester AC, Grimbacher B; ESID Clinical and Registry Working Parties; Gennery AR, Seppanen MRJ, Morris EC, Burns SO.  J Allergy Clin Immunol. 2022 Aug;150(2):456-466. doi: 10.1016/j.jaci.2021.10.037. Epub 2021 Dec 15. PMID: 34920033.
120. pUL36 Deubiquitinase Activity Augments Both the Initiation and the Progression of Lytic Herpes Simplex Virus Infection in IFN-Primed Cells. Mohnke J, Stark I, Fischer M, Fischer PM, Schlosser A, Grothey A, O’Hare P, Sodeik B, Erhard F, Dölken L, Hennig T.  J Virol. 2022 Nov 23;96(22):e0096322. doi: 10.1128/jvi.00963-22. Epub 2022 Oct 31. PMID: 36314822; PMCID: PMC9683058.
121. Resolving the polygenic aetiology of a late onset combined immune deficiency caused by NFKB1 haploinsufficiency and modified by PIK3R1 and TNFRSF13B variants. Hargreaves CE, Dhalla F, Patel AM, de Oteyza ACG, Bateman E, Miller J, Anzilotti C, Ayers L, Grimbacher B, Patel SY.  Clin Immunol. 2022 Jan;234:108910. doi: 10.1016/j.clim.2021.108910. Epub 2021 Dec 15. PMID: 34922003.
122. SARS-CoV-2 Viral Load in the Pulmonary Compartment of Critically Ill COVID-19 Patients Correlates with Viral Serum Load and Fatal Outcomes. Ynga-Durand M, Maaß H, Milošević M, Krstanović F, Pribanić Matešić M, Jonjić S, Protić A, Brizić I, Šustić A, Čičin-Šain L.  Viruses. 2022 Jun 14;14(6):1292. doi: 10.3390/v14061292. PMID: 35746764; PMCID: PMC9228931.
123. The First 4 Years – Outcome of Children Identified by Newborn Screening for CF in Germany. Schütz K, Kontsendorn J, Janzen N, Fuge J, Grewendorf S, Klemann C, Happle C, Junge S, Rudolf I, Dopfer C, Sedlacek L, Renz D, Hansen G, Dittrich AM. Klin Padiatr. 2022 Sep;234(5):284-292. English. doi: 10.1055/a-1700-5105. Epub 2022 Jan 28. PMID: 35098497.
124. The Impact of Evolving SARS-CoV-2 Mutations and Variants on COVID-19 Vaccines. McLean G, Kamil J, Lee B, Moore P, Schulz TF, Muik A, Sahin U, Türeci Ö, Pather S. mBio. 2022 Apr 26;13(2):e0297921. doi: 10.1128/mbio.02979-21. Epub 2022 Mar 30. PMID: 35352979; PMCID: PMC9040821.
125. Baseline Cellular Antiviral State Is Maintained by cGAS and Its Most Frequent Naturally Occurring Variant rs610913. Kazmierski J, Elsner C, Döhner K, Xu S, Ducroux A, Pott F, Jansen J, Thorball CW, Zeymer O, Zhou X, Fedorov R, Fellay J, Löffler MW, Weber ANR, Sodeik B, Goffinet C. A  J Immunol. 2022 Aug 1;209(3):535-547. doi: 10.4049/jimmunol.2100685. PMID: 35851540.
126. The membrane-active polyaminoisoprenyl compound NV716 re-sensitizes Pseudomonas aeruginosa to antibiotics and reduces bacterial virulence. Wang G, Brunel JM, Preusse M, Mozaheb N, Willger SD, Larrouy-Maumus G, Baatsen P, Häussler S, Bolla JM, Van Bambeke F. Commun Biol. 2022 Aug 25;5(1):871. doi: 10.1038/s42003-022-03836-5. PMID: 36008485; PMCID: PMC9411590.
127. NK cell dysfunction in severe COVID-19: TGF-β-induced downregulation of integrin beta-2 restricts NK cell cytotoxicity. Barros-Martins J, Förster R, Bošnjak B.  Signal Transduct Target Ther. 2022 Jan 31;7(1):32. doi: 10.1038/s41392-022-00892-5. PMID: 35102142; PMCID: PMC8801552.
128. Atopic Eczema: Pathophysiological Findings as the Beginning of a New Era of Therapeutic Options. Traidl S, Werfel T, Traidl-Hoffmann C. Handb Exp Pharmacol. 2022;268:101-115. doi: 10.1007/164_2021_492. PMID: 34236520.
129. Differential interferon-α subtype induced immune signatures are associated with suppression of SARS-CoV-2 infection. Schuhenn J, Meister TL, Todt D, Bracht T, Schork K, Billaud JN, Elsner C, Heinen N, Karakoese Z, Haid S, Kumar S, Brunotte L, Eisenacher M, Di Y, Lew J, Falzarano D, Chen J, Yuan Z, Pietschmann T, Wiegmann B, Uebner H, Taube C, Le-Trilling VTK, Trilling M, Krawczyk A, Ludwig S, Sitek B, Steinmann E, Dittmer U, Lavender KJ, Sutter K, Pfaender S.  Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2111600119. doi: 10.1073/pnas.2111600119. PMID: 35131898; PMCID: PMC8872780.
130. Editorial: Neuronal and Glial Alterations Caused by Viral Infections. Hernáez B, Viejo-Borbolla A, Cabrera JR.  Front Cell Neurosci. 2022 Apr 5;16:883221. doi: 10.3389/fncel.2022.883221. PMID: 35450209; PMCID: PMC9016110.
131. Interventional Bronchus Occlusion Using Amplatzer Devices – A Promising Treatment Option for Children with Persistent Air Leak. Schütz K, Happel CM, Keil O, Dingemann J, Carlens J, Wetzke M, Müller C, Köditz H, Griese M, Reiter K, Schweiger-Kabesch A, Backendorf A, Scharff A, Bertram H, Schwerk N.  Klin Padiatr. 2022 Sep;234(5):293-300. English. doi: 10.1055/a-1697-5624. Epub 2022 Jan 3. PMID: 34979579.
132. The Inflammasome Activity of NLRP3 Is Independent of NEK7 in HEK293 Cells Co-Expressing ASC. Machtens DA, Bresch IP, Eberhage J, Reubold TF, Eschenburg S.  Int J Mol Sci. 2022 Sep 7;23(18):10269. doi: 10.3390/ijms231810269. PMID: 36142182; PMCID: PMC9499477.
133. Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease. Haring E, Andrieux G, Uhl FM, Krausz M, Proietti M, Sauer B, Esser PR, Martin SF, Pfeifer D, Schmitt-Graeff A, Duyster J, Köhler N, Grimbacher B, Boerries M, Aumann K, Zeiser R, Apostolova P.  Haematologica. 2022 Jul 1;107(7):1538-1554. PMID: 34407601; PMCID: PMC9244832.
134. Copy Number Analysis in a Large Cohort Suggestive of Inborn Errors of Immunity Indicates a Wide Spectrum of Relevant Chromosomal Losses and Gains. Wan R, Schieck M, Caballero-Oteyza A, Hofmann W, Cochino AV, Shcherbina A, Sherkat R, Wache-Mainier C, Fernandez A, Sultan M, Illig T, Grimbacher B, Proietti M, Steinemann D.  J Clin Immunol. 2022 Jul;42(5):1083-1092. Epub 2022 Apr 29.
135. Clinical, Immunological and Molecular Findings of Patients with Severe Combined Immunodeficiency: Introducing of 7 Novel Mutations in 7 Genes. Z Alizadeh, MR Fazlollahi, M Mazinani, M Badalzadeh, H Heydarlou, …  Genes Immun
136. Interferon-Driven Immune Dysregulation in Common Variable Immunodeficiency-Associated Villous Atrophy and Norovirus Infection. Strohmeier V, Andrieux G, Unger S, Pascual-Reguant A, Klocperk A, Seidl M, Marques OC, Eckert M, Gräwe K, Shabani M, von Spee-Mayer C, Friedmann D, Harder I, Gutenberger S, Keller B, Proietti M, Bulashevska A, Grimbacher B, Provaznik J, Benes V, Goldacker S, Schell C, Hauser AE, Boerries M, Hasselblatt P, Warnatz K.  J Clin Immunol. 2023 Feb;43(2):371-390. Epub 2022 Oct 25.
137. Identification of variants in genes associated with autoinflammatory disorders in a cohort of patients with psoriatic arthritis F. Atschekzei, N. Dubrowinskaja, M. Anim, T. Thiele, T. Witte and G. Sogkas RMD Open 2022 Vol. 8 Issue 2 Accession Number: 36113963 PMCID: PMC9486391 DOI: 10.1136/rmdopen-2022-002561
138. Metamizole-Associated Risks in Decompensated Hepatic Cirrhosis B. Schulte, T. L. Tergast, M. Griemsmann, D. Menti, N. Deveci, J. Kahlhöfer, et al. Dtsch Arztebl Int 2022 Vol. 119 Issue 41 Pages 687-693 Accession Number: 35912424 PMCID: PMC9830680 DOI: 10.3238/arztebl.m2022.0280
139. Dual Effect: High NADH Levels Contribute to Efflux-Mediated Antibiotic Resistance but Drive Lethality Mediated by Reactive Oxygen Species A. Arce-Rodríguez, D. Pankratz, M. Preusse, P. I. Nikel and S. Häussler mBio 2022 Vol. 13 Issue 1 Pages e0243421 DOI: 10.1128/mbio.02434-21
140. Identification of variants in genes associated with autoinflammatory disorders in a cohort of patients with psoriatic arthritis F. Atschekzei, N. Dubrowinskaja, M. Anim, T. Thiele, T. Witte and G. Sogkas RMD Open 2022 Vol. 8 Issue 2 Accession Number: 36113963 PMCID: PMC9486391 DOI: 10.1136/rmdopen-2022-002561

1. KIR3DS1 directs NK cell-mediated protection against human adenovirus infections. Jung JM, Ching W, Baumdick ME, Hofmann-Sieber H, Bosse JB, Koyro T, Möller KJ, Wegner L, Niehrs A, Russu K, Ohms M, Zhang W, Ehrhardt A, Duisters K, Spierings E, Hölzemer A, Körner C, Jansen SA, Peine S, Königs I, Lütgehetmann M, Perez D, Reinshagen K, Lindemans CA, Altfeld M, Belderbos M, Dobner T, Bunders MJ. Sci Immunol. 2021 Sep 17;6(63):eabe2942. doi: 10.1126/sciimmunol.abe2942. Epub 2021 Sep 17. PMID: 34533978.
2. Role of the gut microbiota in airway immunity and host defense against respiratory infections. Willers M, Viemann D. Biol Chem. 2021 Oct 4. doi: 10.1515/hsz-2021-0281. Epub ahead of print. PMID: 34599869.
3. Bowel Histology of CVID Patients Reveals Distinct Patterns of Mucosal Inflammation. van Schewick CM, Lowe DM, Burns SO, Workman S, Symes A, Guzman D, Moreira F, Watkins J, Clark I, Grimbacher B.  J Clin Immunol. 2021 Oct 1. doi: 10.1007/s10875-021-01104-5. Epub ahead of print. PMID: 34599484.
4. Specific T cells targeting Staphylococcus aureus fibronectin-binding protein 1 induce a type 2/type 1 inflammatory response in sensitized atopic dermatitis patients. Farag AK, Roesner LM, Wieschowski S, Heratizadeh A, Eiz-Vesper B, Kwok WW, Valenta R, Werfel T. Allergy. 2021 Oct 3. doi: 10.1111/all.15120. Epub ahead of print. PMID: 34601735.
5. Regulatory B cells control airway hyperreactivity and lung remodeling in a murine asthma model. Habener A, Happle C, Grychtol R, Skuljec J, Busse M, Dalüge K, Obernolte H, Sewald K, Braun A, Meyer-Bahlburg A, Hansen G.  J Allergy Clin Immunol. 2021 Jun;147(6):2281-2294.e7. doi: 10.1016/j.jaci.2020.09.041. Epub 2020 Nov 27. PMID: 33249168.
6. The journey of herpesvirus capsids and genomes to the host cell nucleus. Döhner K, Cornelius A, Serrero MC, Sodeik B. Curr Opin Virol. 2021 Oct;50:147-158. doi: 10.1016/j.coviro.2021.08.005. Epub 2021 Aug 28. PMID: 34464845.
7. Klebsiella oxytoca causes colonization resistance against multidrug-resistant K. pneumoniae in the gut via cooperative carbohydrate competition. Osbelt L, Wende M, Almási É, Derksen E, Muthukumarasamy U, Lesker TR, Galvez EJC, Pils MC, Schalk E, Chhatwal P, Färber J, Neumann-Schaal M, Fischer T, Schlüter D, Strowig T. Cell Host Microbe. 2021 Sep 29:S1931-3128(21)00419-4. doi: 10.1016/j.chom.2021.09.003. Epub ahead of print. PMID: 34610293.
8. Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect. Haematologica. Haring E, Uhl FM, Andrieux G, Proietti M, Bulashevska A, Sauer B, Braun LM, de Vega Gomez E, Esser PR, Martin SF, Pfeifer D, Follo M, Schmitt-Graeff A, Buescher J, Duyster J, Grimbacher B, Boerries M, Pearce EL, Zeiser R, Apostolova P. 2021 Aug 1;106(8):2131-2146. doi: 10.3324/haematol.2019.242990. PMID: 32675222; PMCID: PMC8327708.
9. Diagnostic Yield and Therapeutic Consequences of Targeted Next-Generation Sequencing in Sporadic Primary Immunodeficiency. Sogkas G, Dubrowinskaja N, Schütz K, Steinbrück L, Götting J, Schwerk N, Baumann U, Grimbacher B, Witte T, Schmidt RE, Atschekzei F.  Int Arch Allergy Immunol. 2021 Oct 7:1-13. doi: 10.1159/000519199. Epub ahead of print. PMID: 34619682.
10. Neutralization of the SARS-CoV-2 Delta variant after heterologous and homologous BNT162b2 or ChAdOx1 nCoV-19 vaccination. Hammerschmidt SI, Bosnjak B, Bernhardt G, Friedrichsen M, Ravens I, Dopfer-Jablonka A, Hoffmann M, Pöhlmann S, Behrens GMN, Förster R. Cell Mol Immunol. 2021 Oct;18(10):2455-2456. doi: 10.1038/s41423-021-00755-z. Epub 2021 Aug 23. PMID: 34426672; PMCID: PMC8381713.
11. Recent Advances in Developing Treatments of Kaposi’s Sarcoma Herpesvirus-Related Diseases. Naimo E, Zischke J, Schulz TF.  Viruses. 2021 Sep 9;13(9):1797. doi: 10.3390/v13091797. PMID: 34578378; PMCID: PMC8473310.
12. Generation of hiPSC-derived low threshold mechanoreceptors containing axonal termini resembling bulbous sensory nerve endings and expressing Piezo1 and Piezo2. Zhu S, Stanslowsky N, Fernández-Trillo J, Mamo TM, Yu P, Kalmbach N, Ritter B, Eggenschwiler R, Ouwendijk WJD, Mzinza D, Tan L, Leffler A, Spohn M, Brown RJP, Kropp KA, Kaever V, Ha TC, Narayanan P, Grundhoff A, Förster R, Schambach A, Verjans GMGM, Schmidt M, Kispert A, Cantz T, Gomis A, Wegner F, Viejo-Borbolla A. Stem Cell Res. 2021 Sep 11;56:102535. doi: 10.1016/j.scr.2021.102535. Epub ahead of print. PMID: 34607262.
13. Pathogenesis and virulence of herpes simplex virus. Zhu S, Viejo-Borbolla A. Virulence. 2021 Dec;12(1):2670-2702. doi: 10.1080/21505594.2021.1982373. PMID: 34676800.
14. Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells. Formaglio P, Alabdullah M, Siokis A, Handschuh J, Sauerland I, Fu Y, Krone A, Gintschel P, Stettin J, Heyde S, Mohr J, Philipsen L, Schröder A, Robert PA, Zhao G, Khailaie S, Dudeck A, Bertrand J, Späth GF, Kahlfuß S, Bousso P, Schraven B, Huehn J, Binder S, Meyer-Hermann M, Müller AJ. Immunity. 2021 Oct 15:S1074-7613(21)00406-4. doi: 10.1016/j.immuni.2021.09.021. Epub ahead of print. PMID: 34687607.
15. Toll-like Receptors in Viral Encephalitis. Gern OL, Mulenge F, Pavlou A, Ghita L, Steffen I, Stangel M, Kalinke U.  Viruses. 2021 Oct 14;13(10):2065. doi: 10.3390/v13102065. PMID: 34696494.
16. Impact of HBsAg and HBcrAg levels on phenotype and function of HBV-specific T cells in patients with chronic hepatitis B virus infection. Aliabadi E, Urbanek-Quaing M, Maasoumy B, Bremer B, Grasshoff M, Li Y, Niehaus CE, Wedemeyer H, Kraft ARM, Cornberg M. Gut. 2021 Oct 26:gutjnl-2021-324646. doi: 10.1136/gutjnl-2021-324646. Epub ahead of print. PMID: 34702717.
17. Mesenteric Lymph Node Transplantation in Mice to Study Immune Responses of the Gastrointestinal Tract. Haroon Shaikh, Juan Gamboa Vargas, Zeinab Mokhtari, Katja J. Jarick, Maria Ulbrich, Josefina Peña Mosca, Estibaliz Arellano Viera, Caroline Graf, Duc-Dung Le, Katrin G. Heinze, Maike Büttner-Herold, Andreas Rosenwald, Joern Pezoldt, Jochen Huehn, Andreas Beilhack.  Front Immunol. 2021; 12: 689896. Published online 2021 Jul 26.
18. Concatemeric Broccoli reduces mRNA stability and induces aggregates. Rink MR, Baptista MAP, Flomm FJ, Hennig T, Whisnant AW, Wolf N, Seibel J, Dölken L, Bosse JB. PLoS One. 2021 Aug 4;16(8):e0244166. doi: 10.1371/journal.pone.0244166. eCollection 2021. PMID: 34347781 Free PMC article.
19. Quo vadis clinical diagnostic microbiology? Haag S, Häussler S. Clin Microbiol Infect. 2021 Jul 26:S1198-743X(21)00404-3. doi: 10.1016/j.cmi.2021.07.013. Online ahead of print. PMID: 34325069 No abstract available.
20. Tbx21 and Foxp3 Are Epigenetically Stabilized in T-Bet+ Tregs That Transiently Accumulate in Influenza A Virus-Infected Lungs. Elfaki Y, Yang J, Boehme J, Schultz K, Bruder D, Falk CS, Huehn J, Floess S. Int J Mol Sci. 2021 Jul 14;22(14):7522. doi: 10.3390/ijms22147522. PMID: 34299148 Free PMC article.
21. Sequential MAVS and MyD88/TRIF signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes. Ghita L, Breitkopf V, Mulenge F, Pavlou A, Gern OL, Durán V, Prajeeth CK, Kohls M, Jung K, Stangel M, Steffen I, Kalinke U. J Neurosci Res. 2021 Jul 23. doi: 10.1002/jnr.24923. Online ahead of print. PMID: 34296786
22. Distribution of major lymphocyte subsets and memory T-cell subpopulations in healthy adults employing GLP-conforming multicolor flow cytometry. Schultze-Florey CR, Chukhno E, Goudeva L, Blasczyk R, Ganser A, Prinz I, Förster R, Koenecke C, Odak I. Leukemia. 2021 Jul 21. doi: 10.1038/s41375-021-01348-5. Online ahead of print. PMID: 34290358 No abstract available.
23. Deubiquitinating enzymes (DUBs): decipher underlying basis of neurodegenerative diseases. Liu B, Ruan J, Chen M, Li Z, Manjengwa G, Schlüter D, Song W, Wang X. Mol Psychiatry. 2021 Jul 20. doi: 10.1038/s41380-021-01233-8. Online ahead of print. PMID: 34285347 Review.
24. Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination. Barros-Martins J, Hammerschmidt SI, Cossmann A, Odak I, Stankov MV, Morillas Ramos G, Dopfer-Jablonka A, Heidemann A, Ritter C, Friedrichsen M, Schultze-Florey C, Ravens I, Willenzon S, Bubke A, Ristenpart J, Janssen A, Ssebyatika G, Bernhardt G, Münch J, Hoffmann M, Pöhlmann S, Krey T, Bošnjak B, Förster R, Behrens GMN. Nat Med. 2021 Jul 14. doi: 10.1038/s41591-021-01449-9. Online ahead of print. PMID: 34262158
25. Expression of ACKR4 demarcates the „peri-marginal sinus,“ a specialized vascular compartment of the splenic red pulp. Werth K, Hub E, Gutjahr JC, Bosjnak B, Zheng X, Bubke A, Russo S, Rot A, Förster R. Cell Rep. 2021 Jul 13;36(2):109346. doi: 10.1016/j.celrep.2021.109346. PMID: 34260918
26. TACI deficiency – a complex system out of balance. Salzer U, Grimbacher B. Curr Opin Immunol. 2021 Jul 8;71:81-88. doi: 10.1016/j.coi.2021.06.004. Online ahead of print. PMID: 34247095 Review.
27. A rare case of neuro- and otosyphilis in secondary syphilis. Traidl S, Angela Y, Stender A, Kulberg A, Tronnier M, Prenzler NK, Wattjes MP, Kapp A, Stangel M, Schacht V, Werfel T. J Eur Acad Dermatol Venereol. 2021 Jul 9. doi: 10.1111/jdv.17512. Online ahead of print. PMID: 34242450 No abstract available.
28. Atopic Eczema: Pathophysiological Findings as the Beginning of a New Era of Therapeutic Options. Traidl S, Werfel T, Traidl-Hoffmann C. Handb Exp Pharmacol. 2021 Jul 9. doi: 10.1007/164_2021_492. Online ahead of print. PMID: 34236520
29. Transcriptome analysis following neurotropic virus infection reveals faulty innate immunity and delayed antigen presentation in mice susceptible to virus-induced demyelination. Ciurkiewicz M, Floess S, Beckstette M, Kummerfeld M, Baumgärtner W, Huehn J, Beineke A. Brain Pathol. 2021 Jul 6:e13000. doi: 10.1111/bpa.13000. Online ahead of print. PMID: 34231271
30. Improvement of image resolution by combining enhanced confocal microscopy and quantum dot triexciton imaging. Hennig S, Manstein DJ.
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31. Lymph-Derived Neutrophils Primarily Locate to the Subcapsular and Medullary Sinuses in Resting and Inflamed Lymph Nodes. de Castro Pinho J, Förster R. Cells. 2021 Jun 12;10(6):1486. doi: 10.3390/cells10061486. PMID: 34204825 Free PMC article.
32. Structural and Biochemical Characterization of a Dye-Decolorizing Peroxidase from Dictyostelium discoideum. Rai A, Klare JP, Reinke PYA, Englmaier F, Fohrer J, Fedorov R, Taft MH, Chizhov I, Curth U, Plettenburg O, Manstein DJ. Int J Mol Sci. 2021 Jun 10;22(12):6265. doi: 10.3390/ijms22126265. PMID: 34200865 Free PMC article.
33. Free human DNA attenuates the activity of antimicrobial peptides in atopic dermatitis. Kopfnagel V, Dreyer S, Zeitvogel J, Pieper DH, Buch A, Sodeik B, Rademacher F, Harder J, Werfel T. Allergy. 2021 Jun 27. doi: 10.1111/all.14992. Online ahead of print. PMID: 34176149
34. Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses. Yu K, Hammerschmidt SI, Permanyer M, Galla M, Rothe M, Zheng X, Werth K, Martens R, Lueder Y, Janssen A, Friedrichsen M, Bernhardt G, Förster R. Cell Rep. 2021 Jun 22;35(12):109273. doi: 10.1016/j.celrep.2021.109273. PMID: 34161766
35. There is no gene for CVID – novel monogenetic causes for primary antibody deficiency. Ramirez NJ, Posadas-Cantera S, Caballero-Oteyza A, Camacho-Ordonez N, Grimbacher B. Curr Opin Immunol. 2021 Jun 18;72:176-185. doi: 10.1016/j.coi.2021.05.010. Online ahead of print. PMID: 34153571 Review.
36. Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation. Samarina N, Ssebyatika G, Tikla T, Waldmann JY, Abere B, Nanna V, Marasco M, Carlomagno T, Krey T, Schulz TF. PLoS Pathog. 2021 Jun 18;17(6):e1009635. doi: 10.1371/journal.ppat.1009635. eCollection 2021 Jun. PMID: 34143834 Free PMC article.
37. Therapeutic options for CTLA-4 insufficiency. Egg D, Rump IC, Mitsuiki N, Rojas-Restrepo J, Maccari ME, Schwab C, Gabrysch A, Warnatz K, Goldacker S, Patiño V, Wolff D, Okada S, Hayakawa S, Shikama Y, Kanda K, Imai K, Sotomatsu M, Kuwashima M, Kamiya T, Morio T, Matsumoto K, Mori T, Yoshimoto Y, Dybedal I, Kanariou M, Kucuk ZY, Chapdelaine H, Petruzelkova L, Lorenz HM, Sullivan KE, Heimall J, Moutschen M, Litzman J, Recher M, Albert MH, Hauck F, Seneviratne S, Pachlopnik Schmid J, Kolios A, Unglik G, Klemann C, Snapper S, Giulino-Roth L, Svaton M, Platt CD, Hambleton S, Neth O, Gosse G, Reinsch S, Holzinger D, Kim YJ, Bakhtiar S, Atschekzei F, Schmidt R, Sogkas G, Chandrakasan S, Rae W, Derfalvi B, Marquart HV, Ozen A, Kiykim A, Karakoc-Aydiner E, Králíčková P, de Bree G, Kiritsi D, Seidel MG, Kobbe R, Dantzer J, Alsina L, Armangue T, Lougaris V, Agyeman P, Nyström S, Buchbinder D, Arkwright PD, Grimbacher B. J Allergy Clin Immunol. 2021 Jun 7:S0091-6749(21)00891-5. doi: 10.1016/j.jaci.2021.04.039. Online ahead of print. PMID: 34111452
38. S100A8/A9 is the first predictive marker for neonatal sepsis. Pirr S, Dauter L, Vogl T, Ulas T, Bohnhorst B, Roth J, Viemann D.Clin Transl Med. 2021 Apr;11(4):e338. doi: 10.1002/ctm2.338.PMID: 33931974Free PMC article.No abstract available.
39. MyD88 signaling by neurons induces chemokines that recruit protective leukocytes to the virus-infected CNS. Ghita L, Spanier J, Chhatbar C, Mulenge F, Pavlou A, Larsen PK, Waltl I, Lueder Y, Kohls M, Jung K, Best SM, Förster R, Stangel M, Schreiner D, Kalinke U. Sci Immunol. 2021 Jun 25;6(60):eabc9165. doi: 10.1126/sciimmunol.abc9165. PMID: 34172587.
40. Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction. Franz S, Pott F, Zillinger T, Schüler C, Dapa S, Fischer C, Passos V, Stenzel S, Chen F, Döhner K, Hartmann G, Sodeik B, Pessler F, Simmons G, Drexler JF, Goffinet C.  Life Sci Alliance. 2021 Jun 2;4(7):e202000909. doi: 10.26508/lsa.202000909. PMID: 34078739; PMCID: PMC8200292.
41. Cytomegalovirus subverts macrophage identity. Baasch S, Giansanti P, Kolter J, Riedl A, Forde AJ, Runge S, Zenke S, Elling R, Halenius A, Brabletz S, Hengel H, Kuster B, Brabletz T, Cicin-Sain L, Arens R, Vlachos A, Rohr JC, Stemmler MP, Kopf M, Ruzsics Z, Henneke P. Cell. 2021 Jun 5:S0092-8674(21)00626-7. doi: 10.1016/j.cell.2021.05.009. Online ahead of print. PMID: 34115982
42. Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections. Al-Mekhlafi A, Sühs KW, Schuchardt S, Kuhn M, Müller-Vahl K, Trebst C, Skripuletz T, Klawonn F, Stangel M, Pessler F.  Cells. 2021 May 6;10(5):1115. doi: 10.3390/cells10051115. PMID: 34066349; PMCID: PMC8148106.
43. Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega-7,9 trans-fat rumenic acid. Irene Pertici, Manuel H. Taft, Johannes N. Greve, Roman Fedorov, Marco Caremani, Dietmar J. Manstein. Journal of Physiology. First published: 04 May 2021
44. A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood. Likai Tan, Alina Suzann Fichtner, Elena Bruni, Ivan Odak, Inga Sandrock, Anja Bubke, Alina Borchers, Christian Schultze-Florey, Christian Koenecke, Reinhold Förster, Michael Jarek, Constantin von Kaisenberg, Ansgar Schulz, Xiaojing Chu, Bowen Zhang, Yang Li, Ulf Panzer, Christian F. Krebs, Sarina Ravens, Immo Prinz. Science Immunology 23 Apr 2021
45. Extracellular vesicles in neuroinflammation: Pathogenesis, diagnosis, and therapy. Ruan J, Miao X, Schlüter D, Lin L, Wang X. Mol Ther. 2021 Jun 2;29(6):1946-1957. doi: 10.1016/j.ymthe.2021.04.020. Epub 2021 Apr 23. PMID: 33895328 Review.
46. Ovarian tumor domain proteases in pathogen infection. Review. Trends in Microbiology. Dirk Schlüter, EricSchulze-Niemand, Matthias Stein, Michael Naumann, online 17 May 2021 https://doi.org/10.1016/j.tim.2021.04.002
47. Aging and options to halt declining immunity to virus infections. Miguel Ángel Palacios-Pedrero, Albert D.M.E. Osterhaus, Tanja Becker, Husni Elbahesh, Guus F. Rimmelzwaan and Giulietta Saletti. Front. Immunol., 12 May 2021 | https://doi.org/10.3389/fimmu.2021.681449
48. Eczema herpeticum in atopic dermatitis. Traidl S, Rösner L, Zeitvogel J, Werfel T. Allergy. 2021 Apr 12. doi: 10.1111/all.14853. Online ahead of print. PMID: 33844308 Review.
49. Tim-3 is dispensable for allergic inflammation and respiratory tolerance in experimental asthma. Boehne C, Behrendt AK, Meyer-Bahlburg A, Boettcher M, Drube S, Kamradt T, Hansen G. PLoS One. 2021 Apr 6;16(4):e0249605. doi: 10.1371/journal.pone.0249605. eCollection 2021.
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50. Reverse genetics systems for contemporary isolates of respiratory syncytial virus enable rapid evaluation of antibody escape mutants. Jo WK, Schadenhofer A, Habierski A, Kaiser FK, Saletti G, Ganzenmueller T, Hage E, Haid S, Pietschmann T, Hansen G, Schulz TF, Rimmelzwaan GF, Osterhaus ADME, Ludlow M. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2026558118. doi: 10.1073/pnas.2026558118.
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51. Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells. Pae J, Ersching J, Castro TBR, Schips M, Mesin L, Allon SJ, Ordovas-Montanes J, Mlynarczyk C, Melnick A, Efeyan A, Shalek AK, Meyer-Hermann M, Victora GD. J Exp Med. 2021 Apr 5;218(4):e20201699. doi: 10.1084/jem.20201699. PMID: 33332554
52. Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity. Sogkas G, Atschekzei F, Adriawan IR, Dubrowinskaja N, Witte T, Schmidt RE. Cell Mol Immunol. 2021 Apr 1:1-19. doi: 10.1038/s41423-020-00626-z. Online ahead of print. PMID: 33795850 Free PMC article. Review.
53. Removable denture is a risk indicator for peri-implantitis and facilitates expansion of specific periodontopathogens: a cross-sectional study. Grischke J, Szafrański SP, Muthukumarasamy U, Haeussler S, Stiesch M. BMC Oral Health. 2021 Apr 1;21(1):173. doi: 10.1186/s12903-021-01529-9. PMID: 33794847 Free PMC article.
54. The impact of hepatitis B surface antigen on natural killer cells in patients with chronic hepatitis B infection.
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55. Beyond „Big Eaters“: The Versatile Role of Alveolar Macrophages in Health and Disease. Hetzel M, Ackermann M, Lachmann N. Int J Mol Sci. 2021 Mar 24;22(7):3308. doi: 10.3390/ijms22073308. PMID: 33804918 Free PMC article. Review.
56. The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes. Wiechers C, Zou M, Galvez E, Beckstette M, Ebel M, Strowig T, Huehn J, Pezoldt J. Cell Mol Immunol. 2021 Mar 24. doi: 10.1038/s41423-021-00647-2. Online ahead of print. PMID: 33762684
57. OTUB1 prevents lethal hepatocyte necroptosis through stabilization of c-IAP1 during murine liver inflammation. Koschel J, Nishanth G, Just S, Harit K, Kröger A, Deckert M, Naumann M, Schlüter D. Cell Death Differ. 2021 Mar 12. doi: 10.1038/s41418-021-00752-9. Online ahead of print. PMID: 33712742
58. Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T-cell development in mice. Elfaki Y, Robert PA, Binz C, Falk CS, Bruder D, Prinz I, Floess S, Meyer-Hermann M, Huehn J. Eur J Immunol. 2021 Feb 26. doi: 10.1002/eji.202048981. Online ahead of print. PMID: 33638148
59. Lymph node stromal cell subsets-Emerging specialists for tailored tissue-specific immune responses. Zou M, Wiechers C, Huehn J. Int J Med Microbiol. 2021 Apr;311(3):151492. doi: 10.1016/j.ijmm.2021.151492. Epub 2021 Feb 25. PMID: 33676241
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141. Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation. Häge S, Sonntag E, Svrlanska A, Borst EM, Stilp AC, Horsch D, Müller R, Kropff B, Milbradt J, Stamminger T, Schlötzer-Schrehardt U, Marschall M. Viruses. 2021 Jan 22;13(2):165. doi: 10.3390/v13020165. PMID: 33499341; PMCID: PMC7911381.
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147. The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia. Lühmann JL, Stelter M, Wolter M, Kater J, Lentes J, Bergmann AK, Schieck M, Göhring G, Möricke A, Cario G, Žaliová M, Schrappe M, Schlegelberger B, Stanulla M, Steinemann D.  Cancers (Basel). 2021 Aug 30;13(17):4388. doi: 10.3390/cancers13174388. PMID: 34503197; PMCID: PMC8431583.
148. The effect of keratinized mucosa on the severity of peri-implant mucositis differs between periodontally healthy subjects and the general population: a cross-sectional study. Kabir L, Stiesch M, Grischke J.  Clin Oral Investig. 2021 Mar;25(3):1183-1193. doi: 10.1007/s00784-020-03422-1. Epub 2020 Jul 1. PMID: 32607828; PMCID: PMC7878216.
149. The expansion of human T-bethighCD21low B cells is T cell dependent. Keller B, Strohmeier V, Harder I, Unger S, Payne KJ, Andrieux G, Boerries M, Felixberger PT, Landry JJM, Nieters A, Rensing-Ehl A, Salzer U, Frede N, Usadel S, Elling R, Speckmann C, Hainmann I, Ralph E, Gilmour K, Wentink MWJ, van der Burg M, Kuehn HS, Rosenzweig SD, Kölsch U, von Bernuth H, Kaiser-Labusch P, Gothe F, Hambleton S, Vlagea AD, Garcia Garcia A, Alsina L, Markelj G, Avcin T, Vasconcelos J, Guedes M, Ding JY, Ku CL, Shadur B, Avery DT, Venhoff N, Thiel J, Becker H, Erazo-Borrás L, Trujillo-Vargas CM, Franco JL, Fieschi C, Okada S, Gray PE, Uzel G, Casanova JL, Fliegauf M, Grimbacher B, Eibel H, Ehl S, Voll RE, Rizzi M, Stepensky P, Benes V, Ma CS, Bossen C, Tangye SG, Warnatz K.  Sci Immunol. 2021 Oct 15;6(64):eabh0891. doi: 10.1126/sciimmunol.abh0891. Epub 2021 Oct 8. PMID: 34623902.
150. The human oral phageome. Szafrański SP, Slots J, Stiesch M.  Periodontol 2000. 2021 Jun;86(1):79-96. doi: 10.1111/prd.12363. Epub 2021 Mar 10. PMID: 33690937.
151. The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection. Krüger N, Rocha C, Runft S, Krüger J, Färber I, Armando F, Leitzen E, Brogden G, Gerold G, Pöhlmann S, Hoffmann M, Baumgärtner W.  Int J Mol Sci. 2021 Sep 30;22(19):10636. doi: 10.3390/ijms221910636. PMID: 34638978; PMCID: PMC8508926.
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153. Tutorial: assessing metagenomics software with the CAMI benchmarking toolkit. Meyer F, Lesker TR, Koslicki D, Fritz A, Gurevich A, Darling AE, Sczyrba A, Bremges A, McHardy AC.  Nat Protoc. 2021 Apr;16(4):1785-1801. doi: 10.1038/s41596-020-00480-3. Epub 2021 Mar 1. PMID: 33649565.
154. Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages. Eisfeld HS, Simonis A, Winter S, Chhen J, Ströh LJ, Krey T, Koch M, Theobald SJ, Rybniker J.  Viruses. 2021 Oct 15;13(10):2076. doi: 10.3390/v13102076. PMID: 34696506; PMCID: PMC8538122.
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89. Glucagon-like peptide 2 for intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans. Norona J, Apostolova P, Schmidt D, Ihlemann R, Reischmann N, Taylor G, Köhler N, de Heer J, Heeg S, Andrieux G, Siranosian BA, Schmitt-Graeff A, Pfeifer D, Catalano A, Frew IJ, Proietti M, Grimbacher B, Bulashevska A, Bhatt AS, Brummer T, Clauditz T, Zabelina T, Kroeger N, Blazar BR, Boerries M, Ayuk F, Zeiser R. Blood. 2020 Sep 17;136(12):1442-1455.
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99. Major role of iron uptake systems in the intrinsic extra-intestinal virulence of the genus Escherichia revealed by a genome-wide association study. Galardini M, Clermont O, Baron A, Busby B, Dion S, Schubert S, Beltrao P, Denamur E.  PLoS Genet. 2020 Oct 28;16(10):e1009065. doi: 10.1371/journal.pgen.1009065. PMID: 33112851; PMCID: PMC7592755.
100. Non-Invasive Luciferase Imaging of Type I Interferon Induction in a Transgenic Mouse Model of Biomaterial Associated Bacterial Infections: Microbial Specificity and Inter-Bacterial Species Interactions. Rahim MI, Winkel A, Lienenklaus S, Stumpp NS, Szafrański SP, Kommerein N, Willbold E, Reifenrath J, Mueller PP, Eisenburger M, Stiesch M.  Microorganisms. 2020 Oct 21;8(10):1624. doi: 10.3390/microorganisms8101624. PMID: 33096869; PMCID: PMC7589032.
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104. Protecting-Group-Mediated Diastereoselective Synthesis of C4′-Methylated Uridine Analogs and Their Activity against the Human Respiratory Syncytial Virus. Köllmann C, Sake SM, Jones PG, Pietschmann T, Werz DB.  J Org Chem. 2020 Mar 20;85(6):4267-4278. doi: 10.1021/acs.joc.9b03425. Epub 2020 Feb 26. PMID: 32036652.
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16. STING induces early IFN-β in the liver and constrains myeloid cell-mediated dissemination of murine cytomegalovirus. Tegtmeyer PK, Spanier J, Borst K, Becker J, Riedl A, Hirche C, Ghita L, Skerra J, Baumann K, Lienenklaus S, Doering M, Ruzsics Z, Kalinke U. Nat Commun. 2019 Jun 27;10(1):2830.
17. Constitutive TNF-α signaling in neonates is essential for the development of tissue-resident leukocyte profiles at barrier sites. Bickes MS, Pirr S, Heinemann AS, Fehlhaber B, Halle S, Völlger L, Willers M, Richter M, Böhne C, Albrecht M, Langer M, Pfeifer S, Jonigk D, Vieten G, Ure B, von Kaisenberg C, Förster R, von Köckritz-Blickwede M, Hansen G, Viemann D. FASEB J. 2019 Oct;33(10):10633-10647. Epub 2019 Jun 29.
18. The German National Registry of Primary Immunodeficiencies (2012-2017). El-Helou SM, Biegner AK, Bode S, Ehl SR, Heeg M, Maccari ME, Ritterbusch H, Speckmann C, Rusch S, Scheible R, Warnatz K, Atschekzei F, Beider R, Ernst D, Gerschmann S, Jablonka A, Mielke G, Schmidt RE, Schürmann G, Sogkas G, Baumann UH, Klemann C, Viemann D, von Bernuth H, Krüger R, Hanitsch LG, Scheibenbogen CM, Wittke K, Albert MH, Eichinger A, Hauck F, Klein C, Rack-Hoch A, Sollinger FM, Avila A, Borte M, Borte S, Fasshauer M, Hauenherm A, Kellner N, Müller AH, Ülzen A, Bader P, Bakhtiar S, Lee JY, Heß U, Schubert R, Wölke S, Zielen S, Ghosh S, Laws HJ, Neubert J, Oommen PT, Hönig M, Schulz A, Steinmann S, Schwarz K, Dückers G, Lamers B, Langemeyer V, Niehues T, Shai S, Graf D, Müglich C, Schmalzing MT, Schwaneck EC, Tony HP, Dirks J, Haase G, Liese JG, Morbach H, Foell D, Hellige A, Wittkowski H, Masjosthusmann K, Mohr M, Geberzahn L, Hedrich CM, Müller C, Rösen-Wolff A, Roesler J, Zimmermann A, Behrends U, Rieber N, Schauer U, Handgretinger R, Holzer U, Henes J, Kanz L, Boesecke C, Rockstroh JK, Schwarze-Zander C, Wasmuth JC, Dilloo D, Hülsmann B, Schönberger S, Schreiber S, Zeuner R, Ankermann T, von Bismarck P, Huppertz HI, Kaiser-Labusch P, Greil J, Jakoby D, Kulozik AE, Metzler M, Naumann-Bartsch N, Sobik B, Graf N, Heine S, Kobbe R, Lehmberg K, Müller I, Herrmann F, Horneff G, Klein A, Peitz J, Schmidt N, Bielack S, Groß-Wieltsch U, Classen CF, Klasen J, Deutz P, Kamitz D, Lassay L, Tenbrock K, Wagner N, Bernbeck B, Brummel B, Lara-Villacanas E, Münstermann E, Schneider DT, Tietsch N, Westkemper M, Weiß M, Kramm C, Kühnle I, Kullmann S, Girschick H, Specker C, Vinnemeier-Laubenthal E, Haenicke H, Schulz C, Schweigerer L, Müller TG, Stiefel M, Belohradsky BH, Soetedjo V, Kindle G, Grimbacher B. Front Immunol. 2019 Jul 19;10:1272. eCollection 2019.
19. Diversity of Bacteria Exhibiting Bile Acid-inducible 7alpha-dehydroxylation Genes in the Human Gut. Vital M, Rud T, Rath S, Pieper DH, Schlüter D. Comput Struct Biotechnol J 2019;17:1016-1019
20. Preferential uptake of chitosan-coated PLGA nanoparticles by primary human antigen presenting cells. Durán V, Yasar H, Becker J, Thiyagarajan D, Loretz B, Kalinke U, Lehr CM. Nanomedicine. 2019 Oct;21:102073. Epub 2019 Jul 31.
21. Emerging therapies against infections with Pseudomonas aeruginosa. Tümmler B. F1000Res. 2019 Aug 7;8. pii: F1000 Faculty Rev-1371. eCollection 2019. Review.
22. Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy. Soon CF, Zhang S, Suneetha PV, Antunes DA, Manns MP, Raha S, Schultze-Florey C, Prinz I, Wedemeyer H, Sällberg Chen M, Cornberg M. Front Immunol. 2019 Sep 4;10:2076. eCollection 2019.
23. Tau-protein concentrations are not elevated in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. Möhn N, Luo Y, Skripuletz T, Schwenkenbecher P, Zerr I, Lange P, Stangel M.  Fluids Barriers CNS. 2019 Sep 5;16(1):28.
24. Injection of Antibodies against Immunodominant Epitopes Tunes Germinal Centers to Generate Broadly Neutralizing Antibodies. Meyer-Hermann M. Cell Rep. 2019 Oct 29;29(5):1066-1073.e5.
25. The role of Ames dwarfism and calorie restriction on gut microbiota. Wiesenborn DS, Gálvez EJC, Spinel L, Victoria B, Allen B, Schneider A, Gesing A, Al-Regaiey KA, Strowig T, Schäfer KH, Masternak MM. J Gerontol A Biol Sci Med Sci. 2019 Oct 30.
26. The Antimicrobial and Immunomodulatory Function of RNase 7 in Skin. Rademacher F, Dreyer S, Kopfnagel V, Gläser R, Werfel T, Harder J. Front Immunol. 2019 Nov 5;10:2553.  eCollection 2019. Review.
27. Interleukin-17 cytokines: Effectors and targets in psoriasis-A breakthrough in understanding and treatment. Prinz I, Sandrock I, Mrowietz U. J Exp Med. 2020 Jan 6;217(1):e20191397, epub 2019_11_14
28. Late-Onset Antibody Deficiency Due to Monoallelic Alterations in NFKB1. Schröder C, Sogkas G, Fliegauf M, Dörk T, Liu D, Hanitsch LG, Steiner S, Scheibenbogen C, Jacobs R, Grimbacher B, Schmidt RE, Atschekzei F. Front Immunol. 2019 Nov 14;10:2618. eCollection 2019.
29. Recurrent Eczema Herpeticum – A Retrospective European Multicenter Study Evaluating the Clinical Characteristics of Eczema Herpeticum Cases in Atopic Dermatitis Patients. Seegräber M, Worm M, Werfel T, Svensson A, Novak N, Simon D, Darsow U, Augustin M, Wollenberg A. J Eur Acad Dermatol Venereol 2020;34(5):1074-1079
30. The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens. Zhou N, Jiang Y, Bergquist TR, Lee AJ, Kacsoh BZ, Crocker AW, Lewis KA, Georghiou G, Nguyen HN, Hamid MN, Davis L, Dogan T, Atalay V, Rifaioglu AS, Dalkıran A, Cetin Atalay R, Zhang C, Hurto RL, Freddolino PL, Zhang Y, Bhat P, Supek F, Fernández JM, Gemovic B, Perovic VR, Davidović RS, Sumonja N, Veljkovic N, Asgari E, Mofrad MRK, Profiti G, Savojardo C, Martelli PL, Casadio R, Boecker F, Schoof H, Kahanda I, Thurlby N, McHardy AC, Renaux A, Saidi R, Gough J, Freitas AA, Antczak M, Fabris F, Wass MN, Hou J, Cheng J, Wang Z, Romero AE, Paccanaro A, Yang H, Goldberg T, Zhao C, Holm L, Törönen P, Medlar AJ, Zosa E, Borukhov I, Novikov I, Wilkins A, Lichtarge O, Chi PH, Tseng WC, Linial M, Rose PW, Dessimoz C, Vidulin V, Dzeroski S, Sillitoe I, Das S, Lees JG, Jones DT, Wan C, Cozzetto D, Fa R, Torres M, Warwick Vesztrocy A, Rodriguez JM, Tress ML, Frasca M, Notaro M, Grossi G, Petrini A, Re M, Valentini G, Mesiti M, Roche DB, Reeb J, Ritchie DW, Aridhi S, Alborzi SZ, Devignes MD, Koo DCE, Bonneau R, Gligorijević V, Barot M, Fang H, Toppo S, Lavezzo E, Falda M, Berselli M, Tosatto SCE, Carraro M, Piovesan D, Ur Rehman H, Mao Q, Zhang S, Vucetic S, Black GS, Jo D, Suh E, Dayton JB, Larsen DJ, Omdahl AR, McGuffin LJ, Brackenridge DA, Babbitt PC, Yunes JM, Fontana P, Zhang F, Zhu S, You R, Zhang Z, Dai S, Yao S, Tian W, Cao R, Chandler C, Amezola M, Johnson D, Chang JM, Liao WH, Liu YW, Pascarelli S, Frank Y, Hoehndorf R, Kulmanov M, Boudellioua I, Politano G, Di Carlo S, Benso A, Hakala K, Ginter F, Mehryary F, Kaewphan S, Björne J, Moen H, Tolvanen MEE, Salakoski T, Kihara D, Jain A, Šmuc T, Altenhoff A, Ben-Hur A, Rost B, Brenner SE, Orengo CA, Jeffery CJ, Bosco G, Hogan DA, Martin MJ, O’Donovan C, Mooney SD, Greene CS, Radivojac P, Friedberg I. Genome Biol. 2019 Nov 19;20(1):244.
31. Distinct molecular response patterns of activating STAT3 mutations associate with penetrance of lymphoproliferation and autoimmunity. Jägle S, Heeg M, Grün S, Rensing-Ehl A, Maccari ME, Klemann C, Jones N, Lehmberg K, Bettoni C, Warnatz K, Grimbacher B, Biebl A, Schauer U, Hague R, Neth O, Mauracher A, Pachlopnik Schmid J, Fabre A, Kostyuchenko L, Führer M, Lorenz MR, Schwarz K, Rohr J, Ehl S. Clin Immunol. 2019 Nov 23;210:108316.
32. The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies. Jandus P, Boligan KF, Smith DF, de Graauw E, Grimbacher B, Jandus C, Abdelhafez MM, Despont A, Bovin N, Simon D, Rieben R, Simon HU, Cummings RD, von Gunten S. Blood. 2019 Nov 28;134(22):1941-1950.
33. PedCAPNETZ – prospective observational study on community acquired pneumonia in children and adolescents. Wetzke M, Kopp MV, Seidenberg J, Vogelberg C, Ankermann T, Happle C, Voigt G, Köster H, Illig T, Lex C, Schuster A, Panning M, Barten G, Rohde G, Welte T, Hansen G; pedCAPNETZ Study Group. BMC Pulm Med. 2019 Dec 9;19(1):238.
34. Structural Noninfectious Manifestations of the Central Nervous System in Common Variable Immunodeficiency Disorders. van de Ven A, Mader I, Wolff D, Goldacker S, Fuhrer H, Rauer S, Grimbacher B, Warnatz K. J Allergy Clin Immunol Pract. 2019 Dec 16. pii: S2213-2198(19)31026-8.
35. B cell hyperactivation in an Ackr4-deficient mouse strain is not caused by lack of ACKR4 expression. Eckert N, Werth K, Willenzon S, Tan L, Förster R. J Leukoc Biol. 2019 Dec 16.
36. Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score Tesch VK, Abolhassani H, Shadur B, Zobel J, Mareika Y, Sharapova S, Karakoc-Aydiner E, Rivière JG, Garcia-Prat M, Moes N, Haerynck F, Gonzales-Granado LI, Santos Pérez JL, Mukhina A, Shcherbina A, Aghamohammadi A, Hammarström L, Dogu F, Haskologlu S, İkincioğulları AI, Köstel Bal S, Baris S, Kilic SS, Karaca NE, Kutukculer N, Girschick H, Kolios A, Keles S, Uygun V, Stepensky P, Worth A, van Montfrans JM, Peters AMJ, Meyts I, Adeli M, Marzollo A, Padem N, Khojah AM, Chavoshzadeh Z, Avbelj Stefanija M, Bakhtiar S, Florkin B, Meeths M, Gamez L, Grimbacher B, Seppänen MRJ, Lankester A, Gennery AR, Seidel MG; J Allergy Clin Immunol 2020 May;145(5):1452-1463. Epub 2019 Dec 27.
37. Targeting the Kaposi Sarcoma Herpesvirus ORF 21 tyrosine kinase and viral lytic reactivation by tyrosine kinase inhibitors approved for clinical use. Beauclair G, Naimo E, Dubich T, Rückert J, Koch S, Dhingra A, Wirth D, Schulz TF. J Virol. 2019 Dec 11. pii: JVI.01791-19. doi: 10.1128/JVI.01791-19. [Epub ahead of print]
38. Control of Nipah Virus Infection in Mice by the Host Adaptors Mitochondrial Antiviral Signaling Protein (MAVS) and Myeloid Differentiation Primary Response 88 (MyD88). Iampietro M, Aurine N, Dhondt KP, Dumont C, Pelissier R, Spanier J, Vallve A, Raoul H, Kalinke U, Horvat B. J Infect Dis. 2020 May 11;221(Suppl 4):S401-S406. Dec 19
39. RNA-Based Adjuvants: Immunoenhancing Effect on Antiviral Vaccines and Regulatory Considerations. Ziegler A, Hinz T, Kalinke U. Crit Rev Immunol. 2019;39(1):1-14.
40. Update of the statements on biology and clinical impact of occult hepatitis B virus infection. Raimondo G, Locarnini S, Pollicino T, Levrero M, Zoulim F, Lok AS; Taormina Workshop on Occult HBV Infection Faculty Members.  J Hepatol. 2019 Aug;71(2):397-408. doi: 10.1016/j.jhep.2019.03.034. Epub 2019 Apr 18. PMID: 31004683.
41. Synthesis of 4’/5′-Spirocyclopropanated Uridine and d-Xylouridine Derivatives and Their Activity against the Human Respiratory Syncytial Virus. Köllmann C, Wiechert SM, Jones PG, Pietschmann T, Werz DB. Org Lett. 2019 Sep 6;21(17):6966-6971. doi: 10.1021/acs.orglett.9b02555. Epub 2019 Aug 21. PMID: 31433193.
42. Quantitative Microscopy Reveals Stepwise Alteration of Chromatin Structure during Herpesvirus Infection. Aho V, Mäntylä E, Ekman A, Hakanen S, Mattola S, Chen JH, Weinhardt V, Ruokolainen V, Sodeik B, Larabell C, Vihinen-Ranta M. Viruses. 2019 Oct 11;11(10):935. doi: 10.3390/v11100935. PMID: 31614678; PMCID: PMC6832731.
43. Probabilistic variable-length segmentation of protein sequences for discriminative motif discovery (DiMotif) and sequence embedding (ProtVecX). Asgari E, McHardy AC, Mofrad MRK. Sci Rep. 2019 Mar 5;9(1):3577. doi: 10.1038/s41598-019-38746-w. PMID: 30837494; PMCID: PMC6401088.
44. Keratinized mucosa width is associated with severity of peri-implant mucositis. A cross-sectional study. Jasmin Grischke, Annika Karch, Andreas Wenzlaff, Magdalena Marta Foitzik, Meike Stiesch, Jörg Eberhard. Clinical Oral Implants Research. First published: 10 April 2019. https://doi.org/10.1111/clr.13432
45. Impaired cellular energy metabolism in cord blood macrophages contributes to abortive response toward inflammatory threats. Dreschers S, Ohl K, Lehrke M, Möllmann J, Denecke B, Costa I, Vogl T, Viemann D, Roth J, Orlikowsky T, Tenbrock K. Nat Commun. 2019 Apr 11;10(1):1685. doi: 10.1038/s41467-019-09359-8. PMID: 30976008; PMCID: PMC6459909.
46. HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0. J Neuroinflammation. Hensel N, Raker V, Förthmann B, Detering NT, Kubinski S, Buch A, Katzilieris-Petras G, Spanier J, Gudi V, Wagenknecht S, Kopfnagel V, Werfel TA, Stangel M, Beineke A, Kalinke U, Paludan SR, Sodeik B, Claus P. 2019 Dec 2;16(1):248. doi: 10.1186/s12974-019-1647-5. PMID: 31791351; PMCID: PMC6889453.
47. Hepatitis D Virus-Specific CD8+ T Cells Have a Memory-Like Phenotype Associated With Viral Immune Escape in Patients With Chronic Hepatitis D Virus Infection. Kefalakes H, Koh C, Sidney J, Amanakis G, Sette A, Heller T, Rehermann B.  Gastroenterology. 2019 May;156(6):1805-1819.e9. doi: 10.1053/j.gastro.2019.01.035. Epub 2019 Jan 18. PMID: 30664876; PMCID: PMC7367679.
48. Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung. Kordes A, Preusse M, Willger SD, Braubach P, Jonigk D, Haverich A, Warnecke G, Häussler S.  Nat Commun. 2019 Jul 30;10(1):3397. doi: 10.1038/s41467-019-11414-3. PMID: 31363089; PMCID: PMC6667473.
49. Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 Philine Kirsch, Valentin Jakob, +4 authors M. Empting. Journal of Medicinal Chemistry. 19 March 2019 DOI:10.1021/acs.jmedchem.8b01827Corpus ID: 84183173
50. Establishment of an induced memory response in Pseudomonas aeruginosa during infection of a eukaryotic host. Kordes A, Grahl N, Koska M, Preusse M, Arce-Rodriguez A, Abraham WR, Kaever V, Häussler S. ISME J. 2019 Aug;13(8):2018-2030. doi: 10.1038/s41396-019-0412-1. Epub 2019 Apr 5. PMID: 30952997; PMCID: PMC6775985.
51. Diversity of Bacteria Exhibiting Bile Acid-inducible 7α-dehydroxylation Genes in the Human Gut. Vital M, Rud T, Rath S, Pieper DH, Schlüter D.  Comput Struct Biotechnol J. 2019 Jul 26;17:1016-1019. doi: 10.1016/j.csbj.2019.07.012. PMID: 31428294; PMCID: PMC6692061.
52. Cohort profile: The LoewenKIDS Study – life-course perspective on infections, the microbiome and the development of the immune system in early childhood. Gottschick C, Raupach-Rosin H, Langer S, Hassan L, Horn J, Dorendorf E, Caputo M, Bittner M, Beier L, Rübsamen N, Schlinkmann K, Zoch B, Guzman CA, Hansen G, Heselich V, Holzapfel E, Hübner J, Pietschmann T, Pieper DH, Pletz M, Riese P, Schmidt-Pokrzywniak A, Hartwig S, von Kaisenberg C, Aydogdu M, Buhles M, Dressler F, Eberl W, Haase R, von Koch FE, Feidicker S, Frambach T, Franz HGB, Guthmann F, Koch HG, Seeger S, Oberhoff C, Pauker W, Petry KU, Schild RL, Tchirikov M, Röhrig E, Karch A, Mikolajczyk R. Int J Epidemiol. 2019 Aug 1;48(4):1382-1383. doi: 10.1093/ije/dyz069. Erratum for: Int J Epidemiol. 2019 Aug 1;48(4):1042-1043h. PMID: 30938437; PMCID: PMC7263872.
53. Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2. Klemann C, Camacho-Ordonez N, Yang L, Eskandarian Z, Rojas-Restrepo JL, Frede N, Bulashevska A, Heeg M, Al-Ddafari MS, Premm J, Seidl M, Ammann S, Sherkat R, Radhakrishnan N, Warnatz K, Unger S, Kobbe R, Hüfner A, Leahy TR, Ip W, Burns SO, Fliegauf M, Grimbacher B. Front Immunol. 2019 Mar 19;10:297. doi: 10.3389/fimmu.2019.00297. PMID: 30941118; PMCID: PMC6435015.
54. Autophagic degradation of lamins facilitates the nuclear egress of herpes simplex virus type 1. Turan A, Grosche L, Krawczyk A, Mühl-Zürbes P, Drassner C, Düthorn A, Kummer M, Hasenberg M, Voortmann S, Jastrow H, Dörrie J, Schaft N, Kraner M, Döhner K, Sodeik B, Steinkasserer A, Heilingloh CS. J Cell Biol. 2019 Feb 4;218(2):508-523. doi: 10.1083/jcb.201801151. Epub 2018 Dec 26. PMID: 30587512; PMCID: PMC6363456.
55. Kynurenine Is a Cerebrospinal Fluid Biomarker for Bacterial and Viral Central Nervous System Infections Sühs KW, Novoselova N, Kuhn M, Seegers L, Kaever V, Müller-Vahl K, Trebst C, Skripuletz T, Stangel M, Pessler F.  J Infect Dis. 2019 Jun 5;220(1):127-138.
56. HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein ICP0 Hensel N, Raker V, Förthmann B, Detering NT, Kubinski S, Buch A, Katzilieris-Petras G, Spanier J, Gudi V, Wagenknecht S, Kopfnagel V, Werfel TA, Stangel M, Beineke A, Kalinke U, Paludan SR, Sodeik B, Claus P.  J Neuroinflammation 2019;16(1):248
57. Kynurenine Is a Cerebrospinal Fluid Biomarker for Bacterial and Viral Central Nervous System Infections K. W. Sühs, N. Novoselova, M. Kuhn, L. Seegers, V. Kaever, K. Müller-Vahl, et al. J Infect Dis 2019 Vol. 220 Issue 1 Pages 127-138 Accession Number: 30721966 DOI: 10.1093/infdis/jiz048

Vorarbeiten

• Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung. Kordes A, Preusse M, Willger SD, Braubach P, Jonigk D, Haverich A, Warnecke G, Häussler S. Nat Commun. 2019 Jul 30;10(1):3397.
• Establishment of an induced memory response in Pseudomonas aeruginosa during infection of a eukaryotic host. Kordes A, Grahl N, Koska M, Preusse M, Arce-Rodriguez A, Abraham WR, Kaever V, Häussler S. ISME J. 2019 Aug;13(8):2018-2030.
• Single-Cell Transcriptomics Identifies the Adaptation of Scart1(+) Vγ6(+) T Cells to Skin Residency as Activated Effector Cells. Tan L*, Sandrock I*, Odak I, Aizenbud Y, Wilharm A, Barros-Martins J, Tabib Y, Borchers A, Amado T, Gangoda L, Herold MJ, Schmidt-Supprian M, Kisielow J, Silva-Santos B, Koenecke C, Hovav AH, Krebs C, Prinz I**, Ravens S**. Cell Rep. 2019 Jun 18;27(12):3657-3671.e4.
• The deubiquitinase OTUB1 inhibits central nervous system autoimmunity by preventing IFN-γ-induced hyperactivation of astrocytes through stabilization of SOCS1 X. Wang, F. Mulas, W Yi, A. Brunn, G. Nishanth, S. Just, A. Waisman, W. Brück, M. Deckert, D. Schlüter (2019) . EMBO J e100947.
• Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus/Human Herpesvirus 8. Kirsch P, Jakob V, Oberhausen K, Stein SC, Cucarro I, Schulz TF, Empting M. J Med Chem. 2019 Apr 25;62(8):3924-3939. doi: 10.1021/acs.jmedchem.8b01827. Epub 2019 Apr 12. PMID: 30888817.
•  Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening. Prakash O, Führing J, Post J, Shepherd SM, Eadsforth TC, Gray D, Fedorov R and Routier FH.  2019, Molecules, 24(5): 996.
• Current In Vitro Models to Study Varicella Zoster Virus Latency and Reactivation. Baird NL, Zhu S, Pearce CM, Viejo-Borbolla A. Viruses. 2019 Jan 26;11(2):103. doi: 10.3390/v11020103. PMID: 30691086; PMCID: PMC6409813.
• Novel Virus Related to Kaposi’s Sarcoma-Associated Herpesvirus from Colobus Monkey Dhingra A, Ganzenmueller T, Hage E, Suárez NM, Mätz-Rensing K, Widmer D, Pöhlmann S, Davison AJ, Schulz TF, Kaul A. Emerg Infect Dis 2019;25(8):1548-1551
• Kaposi’s sarcoma-associated herpesvirus vIRF2 protein utilizes an IFN-dependent pathway to regulate viral early gene expression Koch S, Damas M, Freise A, Hage E, Dhingra A, Rückert J, Gallo A, Kremmer E, Tegge W, Brönstrup M, Brune W, Schulz TF. PLoS Pathog 2019;15(5):e1007743
• Severe Progressive Multifocal Leukoencephalopathy (PML) and Spontaneous Immune Reconstitution Inflammatory Syndrome (IRIS) in an Immunocompetent Patient. Krey L, Raab P, Sherzay R, Berding G, Stoll M, Stangel M, Wegner F. Front Immunol 2019;10:1188
• Diversity patterns of bacteriophages infecting Aggregatibacter and Haemophilus species across clades and niches. Szafrański SP, Kilian M, Yang I, Bei der Wieden G, Winkel A, Hegermann J, Stiesch M.  ISME J.

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