Interaction between the immune system and the microbiome is also being studied in relation to another medical condition affecting adults. This is spondyloarthrosis, a class of rheumatic diseases that manifest as inflammation of the musculoskeletal system, and whose onset is triggered by an infection.
RESIST will investigate the influence the gut microbiome has on whether the patient recovers from this condition or whether it becomes chronic.
In elderly people, the RESIST team will look at factors such as their vulnerability to flu viruses or the chicken pox virus, which causes shingles. Another research focus in RESIST, where older people are involved, is vaccination. It is still not clear why vaccination of elderly individuals is often not as effective or completely useless. The development of new vaccines and innovative therapies are of interest in several RESIST projects dealing with hepatitis.