Welcome to the RESIST study area!
You help us with our research – because our RESIST studies are based on data from patients and healthy people. Thereby you provide us scientists with precious information for our research.
On these pages you will learn more about our clinical studies. For example, we have compiled a complete overview of studies based on patient data RESIST is working with.
Our study with healthy people started on December 12, 2019. On the corresponding study page, you as a participant will find comprehensive information about the study implementation.
How healthy people promote science
How does the immune system of a healthy person differ from that of a sick person? Why does the immune system of older people sometimes not defend so well against pathogens? Why do vaccinations in some cases have a weaker effect on older people? To better understand the individual susceptibility to infections, RESIST is building a new cohort. By 2023, a total of 650 citizens from Hanover will be included in this cohort after they have been randomly selected and have agreed to participate.
The volunteers will be asked about their lifestyle, previous illnesses and medication, but also about measurements such as blood pressure and examinations, for example of the skin. In particular, laboratory tests are also carried out.
How sick people help research
Why are some people more susceptible to infections than others? In order to investigate the central question of RESIST, we conduct studies on immune functions. These studies are based on patient information from 14 so-called cohorts – constantly growing recruited groups of people with the same disease. The cohorts already exist or are newly created and, depending on the cohort, should comprise 150 to 1,500 persons.
For example, RESIST is currently establishing two cohorts on severe herpes diseases. There is also a cohort for children up to two years old who have severe respiratory problems due to an infection with respiratory syncytial virus (RSV). Another group are children with the disease cystic fibrosis, who often suffer from severe pneumonia.
Another group are children with the disease cystic fibrosis, who often suffer from severe pneumonia.
Numerous cohorts are dedicated to infectious diseases in adults: For example, people suffering from severe shingles attacks can be included in a cohort – as well as neurodermatitis patients suffering from the severe skin disease eczema herpeticatum.
But also women and men with congenital immune defects, chronically inflamed bile ducts or viral diseases of the liver such as hepatitis B and hepatitis C are included in cohorts that are scientifically processed in RESIST.