This may even influence survival in (for example) those with the RSV cold virus, which can cause severe to life-threatening respiratory tract infections in young children.
Varicella zoster and herpes simplex viruses may also cause serious diseases, such as shingles or encephalitis.
RESIST will also explore the genetic causes of severe congenital immune deficiencies. For, in many cases, it remains unclear which genetic defects cause these deficiencies and why the immune system does not respond effectively. Bacteria and fungi may lead to severe infection in people with a genetically determined susceptibility to infection.