Bettina

The "cell-sitting" list is something like a ticket for a vacation. Because when Dr. Daniela Paasch wants to take a vacation, she uses it to record exactly how her colleagues can preserve the life of the cells with which the postdoc is conducting research at the MHH Clinic for Pediatric Pneumology, Allergology and Neonatology. With these immune cells, or more precisely macrophages, Dr. Paasch is developing cell therapies against bacteria - as an alternative to antibiotics. She works in Prof. Lachmann's team. "We are testing how effectively different macrophages can fight bacteria, for example tuberculosis bacteria," she says. In doing [...]

Hepatitis D virus infection causes the most severe form of chronic viral hepatitis disease. About ten to 20 million people worldwide are affected. There is currently no cure for the disease, and in the end the only treatment option is often a liver transplant. However, an international team led by Prof. Wedemeyer and Prof. Cornberg has now been able to prove in a multicentre phase 3 study with 150 participants that the active substance Bulevirtide prevents hepatitis D viruses (HDV) from entering the liver. "This means that the prerequisites for full approval of the drug have been fulfilled and [...]

Dr. Bošnjak is a new members of RESIST Dr. Berislav Bošnjak, research associate at the Institute of Immunology of the MHH, is now a member of our Cluster of Excellence. A warm welcome! The research focus of the 44-year-old researcher is on the initiation of the T-cell immune response and its function in infections and allergies. At the moment, he is mainly using cytomegalovirus infections as a model system. "My interest is to find out more about T-cell immune responses and the differences in dendritic cell migration patterns during homeostasis and infection," says the immunologist. Dr. Bošnjak studied molecular [...]

The RESIST team mourns the death of Egbert Trowe, who died on 31 May 2023 at the age of 78. Egbert Trowe himself received a liver transplant in 2002 and has since been an advocate for the issue of organ donation as well as for patients before and after organ transplantation. In November 2022, Egbert Trowe became a patient representative on RESIST's internal advisory board. He has taken up this activity in addition to his numerous other activities in various committees. "We are grateful to Egbert Trowe for his commitment to RESIST. Our sympathies go out to the relatives," [...]

What funding opportunities are there for young researchers at the DFG? What is absolutely necessary for a good proposal? And what should I absolutely refrain from doing? Dr. Andreas Strecker from the DFG Head Office answered all these and many other questions for a group of around 100 interested people in the Twincore seminar room on 2 June. He presented funding programmes that can provide support at various points in a career and provided his explanations with numerous tips and examples based on his extensive experience. In addition, the programme director of the Life Sciences 2: Microbiology, Immunology, Neurosciences [...]

As part of the German-Scottish project "Hannover-Glasgow Infection Strategy" (HAGIS), the RESIST team was visited by five guests from the Glasgow Centre for Virus Research (CVR) on 24 and 25 May. At their meeting at the Institute of Virology of the Hannover Medical School (MHH), four young researchers reported on previous and planned research stays in Glasgow, discussed further mutual exchanges and possible collaborations on various research topics, strategies for further funding of the project and possible focal points for a currently planned joint graduate college. The social part of the visit was not neglected either, for example during [...]

The German Research Foundation has approved the new research training group "VISualisation and imaging of virus InfectION (VISION)". The spokesperson is Professor Dr Thomas Krey, head of the Institute of Biochemistry at the University of Lübeck, and the co-spokesperson and co-applicant is Professor Dr Kay Grünewald from the University of Hamburg. In the coming years, the two RESIST members will dedicate themselves to training the next generation of scientists in state-of-the-art structural analysis and imaging techniques to combat viral infectious diseases. More information can be found on the homepage of the University of Lübeck. The photo shows Prof. Krey [...]

Research team of the MHH and the Cluster of Excellence RESIST clarify cell mechanism. The result is the basis for new therapies. How do human cells defend themselves against adenoviruses? The team of RESIST Professor Dr. Sabrina Schreiner from the Institute of Virology at the Hannover Medical School (MHH) has come a good deal closer to answering this question. The team has elucidated an important defence mechanism and thus laid the foundation for the development of new treatment options. The research results, which were made possible through the RESIST Cluster of Excellence, were published in the scientific journal mbio. [...]