Bettina

We welcome Dr. Lennart Rösner as a new member of RESIST: Atopic dermatitis - this is the name given to the chronic inflammatory and agonisingly itchy skin disease. It begins with a defect in the skin barrier in interaction with changes in the immune system. The triggers for a worsening can be allergens, skin irritating substances, mechanical stimuli, psychological stress as well as bacterial infections and some affected persons have an increased susceptibility to viral diseases. In order to be able to help them in the long term, Dr. Lennart Rösner is exploring the cellular immune response to Staphylococcus [...]

Aspergillus fumigatus protects itself from antimycotics and the immune defence by biofilm. But the cancer drug Imatinib can prevent the compartmentalisation: When immunocompromised people breathe in the spores of the fungus Aspergillus fumigatus, this can trigger aspergillosis. This infection is particularly difficult to treat because the fungus surrounds itself with a biofilm and thus protects itself from attacks by the immune system and especially against anti-fungal drugs. The team led by Prof. Routier (RESIST project C3) from the MHH Institute of Clinical Biochemistry has now succeeded in preventing the formation of such an Aspergillus biofilm with the help of [...]

To be able to treat patients with infectious diseases even better individually - that is the goal of the Centre for Individualised Infection Medicine (CiiM), which is headed by RESIST members Professor Dr. Markus Cornberg and Professor Dr. Yang Li. With its own building, the foundation stone of which has now been laid, the interactions between CiiM and RESIST will also increase. Read all about it in the cover story starting on page 6 of the current issue of MHH Info. (in German language) The photo shows (from left): Professor Dr. Yang Li, Professor Dr. Markus Cornberg and Dr. [...]

The outbreak of H5N1 avian influenza in a Spanish mink farm is raising concerns about transmission to humans. Raccoons, foxes and martens - bird flu viruses have already been found in these and other mammals. Humans have also been infected and have died from it. In these incidents, the viruses have usually passed from a bird to a mammal in isolated cases. But in the avian flu outbreak at a Spanish mink farm in October 2022, the H5N1 avian flu virus spread from mink to mink. A mutation was found in the sequenced viruses from this outbreak that could indicate [...]

Repairing tissue and organs: Else Kröner-Fresenius Foundation supports new MHH training programme nextGENERATION with one million euros. The new training programme nextGENERATION on regenerative medicine is starting this year at the Hannover Medical School (MHH). It is aimed at young scientists with a doctorate. The Else Kröner-Fresenius Foundation (EKFS) is funding it with one million euros. "One of the main goals of nextGENERATION is to translate regenerative concepts into advanced therapies for patients. To do this, we use cutting-edge technologies of regenerative medicine to repair tissues and organs, such as stem cell-based therapies and gene therapies," describes Professor Dr. [...]

We wish all members of RESIST and all other readers of this homepage a Merry Christmas and a successful and good year 2023. You can find a greeting for the turn of the year in our current newsletter. There you will also find interesting research topics, reports on new members and students as well as on events. We hope you enjoy reading it! The photo shows the RESIST speaker trio Prof. Schulz, Prof. Hansen and Prof. Förster (from bottom to top) with the the new RESIST roll up. The RESIST Newsletter 3/2022