Bettina, Author at RESIST

Particularly potent antibodies should help against SARS-CoV-2

Particularly potent antibodies should help against SARS-CoV-2

People who have successfully mastered an infection with SARS-CoV-2 have various protective antibodies in their blood. Some of these substances are particularly effective. Detecting these highly potent antibodies, producing them genetically in the laboratory and then using them to protect against infection and to treat the disease – this is the goal of the team led by RESIST speaker Professor Schulz and MHH professors Blasczyk and Haverich. The Lower Saxony Ministry of Science and Culture is supporting this project with around 1.2 million euros. "We are looking for antibodies that prevent the viruses from binding to human cells – [...]

Bettina2022-05-12T11:12:00+02:00 18. May 2020|

With smallpox vaccination vector against the new Coronavirus

With smallpox vaccination vector against the new Coronavirus

In his search for a suitable vaccine against the coronavirus SARS-CoV-2, Professor Förster relies on old friends. In cooperation with the Ludwig-Maximilians-Universität München (LMU), the co-speaker of RESIST is testing a promising vaccine based on a smallpox virus. The Modified Vaccinia Virus Ankara (MVA) has been used as a vehicle since the early 1990s to introduce genetic material into body cells and trigger an immune reaction. Now the scientists want to modify the smallpox vaccine with the building instructions for the so-called spike or S protein, which is located on the surface of SARS-CoV-2 and enables the infection of [...]

Bettina2022-05-12T11:12:09+02:00 15. May 2020|

First RESIST professorships have been appointed

First RESIST professorships have been appointed

Sarina Ravens and Jens Bosse received their certificates of professorship appointment on 30th April 2020 at the MHH Presidium. Since May, they have obtained the first professorships financed by the Cluster of Excellence RESIST. Professor Dr. Sarina Ravens is now Professor of Systemic Human Immunology. She has already been involved in developing and leading the RESIST research projects B3 and B5. Together with her research group at the MHH Institute of Immunology, she dedicates herself during her professorship to B and T cells of the immune system and investigates how these white blood cells functionally adapt depending on environmental [...]

Bettina2022-05-12T11:12:15+02:00 8. May 2020|

Searching for drugs against SARS-CoV-2

Searching for drugs against SARS-CoV-2

RESIST-Scientist Professor Pietschmann leads the German part of an international consortium of scientists. This research network is searching for substances that act against SARS-CoV-2 in the world's largest substance repurposing bank "ReFrame". Innovations based on proven active ingredients, new indications for established drugs – the principle of repurposing has often led to success in medicine. This is why it is also used against SARS-CoV-2: In order to quickly find a drug to treat COVID-19, this international research network is searching for substances that act against SARS-CoV-2 in the world's largest substance repurposing bank "ReFrame". The collection comprises around 14,000 [...]

Bettina2022-05-12T11:13:01+02:00 24. April 2020|

RESIST-Research on the coronavirus SARS-CoV-2

RESIST-Research on the coronavirus SARS-CoV-2

Many different research projects on SARS-CoV-2 are carried out in the Cluster of Excellence RESIST - always with the aim of protecting and treating people in the best possible way. Professor Schulz gives an overview of the work: Professor Schulz, what are RESIST scientists researching with regard to SARS-CoV-2? The aim of RESIST is to improve our understanding of the molecular basis of an increased susceptibility to infectious disease together with the causative bacterial or viral pathogens. These new insights will in the long term lead to new approaches to diagnosis and therapy. When RESIST started at the beginning [...]

Bettina2022-01-12T12:24:42+01:00 17. April 2020|

Answers to questions about the novel coronavirus

Answers to questions about the novel coronavirus

Professor Schulz answered numerous questions about the novel coronavirus, together with MHH colleagues. The interview can be found here (on the homepage of the Hanover Medical School). More information about our research

Bettina2022-05-12T11:13:09+02:00 15. April 2020|

New in our RESIST team: Dr. Gerold

New in our RESIST team: Dr. Gerold

Dr. Gisa Gerold, Researcher of the TWINCORE – Centre for Experimental and Clinical Infection Research and visiting professor at Umea University in Sweden, is associated with RESIST: Her PhD student Lisa Laßwitz will be funded by RESIST for six months. Dr. Gerold's team investigates, within the framework of RESIST, the genetic basis for susceptibility to Chikungunya virus infections. The virus is transmitted from mosquitoes to humans and can cause arthritis-like chronic joint pain. The virus is widespread in many African and Asian countries and in Central and South America, but also occurs sporadically in Europe. ”In the future, the [...]

Bettina2022-05-12T11:12:23+02:00 14. April 2020|

Five RESIST researchers elected to DFG Review Boards

Five RESIST researchers elected to DFG Review Boards

Five researchers of our Cluster of Excellence RESIST have been elected to the Review Boards of the German Research Foundation (DFG): Professor Dr. Gesine Hansen has been elected to the Review Board "Child and Youth Medicine", Professor Dr. Beate Sodeik and Professor Dr. Thomas Pietschmann to the Review Board "Microbiology, Virology and Immunology", Professor Dr. Bodo Grimbacher to the Review Board "Clinical Immunology and Allergology" and Professor Dr. Meike Stiesch to the Review Board "Dentistry; Oral and Maxillofacial Surgery". Review Boards are responsible for scientific evaluation of proposals submitted to the DFG for financial support and for monitoring of [...]

Bettina2022-05-12T11:12:40+02:00 3. March 2020|

Genome analysis: new technology established

Genome analysis: new technology established

The RESIST team of Professor Dr. Doris Steinemann and Professor Dr. Thomas Illig (right) is proud of a new large-scale device: the BioNano Saphyr. This technology can be used to investigate genetic changes that underlie diseases and are difficult to detect with sequencing technologies. "We are now one of six locations in Germany where such genetic analyses can be performed. We invite all researchers working in RESIST to cooperate with us," says Professor Steinemann. Initially, the team will focus on congenital immunodeficiencies. An important goal is to diagnose as many people as possible with a congenital immunodeficiency at an [...]

Bettina2020-03-03T12:34:06+01:00 5. February 2020|

RESIST on stage

RESIST on stage

Coffee is good for the liver! This is one of the many interesting messages that RESIST researcher Professor Dr. Markus Cornberg and PD Dr. Benjamin Maasoumy advised the approximately 320 guests who had come to “Schloß Herrenhausen” for their lecture on the evening of January 22. The RESIST researcher from the MHH Clinic for Gastroenterology, Hepatology and Endocrinology, and his colleague fascinated their audience in an entertaining and really funny way with a humorous stage dialogue as part of the "Herrenhausen Late" event series of the Volkswagen Foundation. Based on a fictitious medical history of the patient Gisela, who [...]

Bettina2020-01-24T09:43:37+01:00 23. January 2020|

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