Almost a year ago, RESIST researcher Prof. Pietschmann from the Twincore Institute for Experimental Virology and his team developed a test system that can be used to precisely measure the immune response against the broad spectrum of hepatitis C viruses (HCV). With the help of this test system, it has now been possible to isolate HCV antibodies in a study that attack an unusually large number of viral variants simultaneously – so-called broadly neutralizing antibodies. These antibodies reveal where the virus is particularly sensitive, which is another step on the way to developing a hepatitis C vaccine. The study, in which RESIST researcher Prof. Krey from the University of L\u00fcbeck is also involved , was led by the team of Prof. Dr. Florian Klein, University Hospital Cologne and German Center for Infection Research. The results were published in the highly respected journal Immunity.<\/p>\n
The figure<\/strong> shows in the form of a crystal structure the binding of an antibody (red and green) to the HCV surface protein “E2” (purple).\u00a0\u00a9 Timm Weber<\/p>\n The publication can be found here.<\/a> Almost a year ago, RESIST researcher Prof. Pietschmann from the Twincore Institute for Experimental Virology and his team developed a test system that can be used to precisely measure the immune response against the broad spectrum of hepatitis C viruses (HCV). With the help of this test system, it has now been possible to isolate HCV antibodies in a study that attack an unusually large number of viral variants simultaneously – so-called broadly neutralizing antibodies. These antibodies reveal where the virus is particularly sensitive, which is another step on the way to developing a hepatitis C vaccine. The study, in […]<\/p>\n","protected":false},"author":4,"featured_media":20022,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[51],"tags":[],"class_list":["post-20015","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/posts\/20015","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/comments?post=20015"}],"version-history":[{"count":8,"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/posts\/20015\/revisions"}],"predecessor-version":[{"id":20029,"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/posts\/20015\/revisions\/20029"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/media\/20022"}],"wp:attachment":[{"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/media?parent=20015"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/categories?post=20015"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.resist-cluster.de\/en\/wp-json\/wp\/v2\/tags?post=20015"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nThe DZIF press release (in german) can be found here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"