{"id":9057,"date":"2020-04-28T10:20:37","date_gmt":"2020-04-28T08:20:37","guid":{"rendered":"https:\/\/www.resist-cluster.de\/?page_id=9057"},"modified":"2022-02-02T13:19:30","modified_gmt":"2022-02-02T12:19:30","slug":"prof-dr-jochen-huehn","status":"publish","type":"page","link":"https:\/\/www.resist-cluster.de\/en\/about-us\/research-team-2\/prof-dr-jochen-huehn\/","title":{"rendered":"Prof. Dr. Jochen H\u00fchn"},"content":{"rendered":"

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Prof. Dr. Jochen H\u00fchn participates in\u00a0RESIST research projects A3 and B1.<\/p>\n<\/div>

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<\/i><\/td>\nMy Research Interest in RESIST<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/h1><\/div>
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Within RESIST we study the impact of microbiota during the neonatal period on the development, maturation and functional specialization of the gastrointestinal and systemic immune system, which is determining the individual\u2019s immune status and susceptibility towards infectious diseases long- lastingly. Although it is widely accepted that microbiota are critically involved in this process, a detailed understanding of the involved microbial communities and microbiota-derived metabolites is still lacking.<\/p>\n

Our research programme is based on our recent finding that early-life colonization by microbiota results in an epigenetic imprinting of unique functional properties within the gastrointestinal immune system and that neonatal infections can interfere with this process. Our long-term goal is to contribute to the development of therapeutic strategies based on early-life microbiome editing leading to a better development, maturation and functional specialization of the gastrointestinal and systemic immune system, thereby improving the health status of individuals long-lastingly.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>

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<\/i><\/span>Contact<\/span><\/a><\/div>
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Prof. H\u00fchn about his scientific work<\/h1><\/div>