{"id":33371,"date":"2024-04-16T13:58:13","date_gmt":"2024-04-16T11:58:13","guid":{"rendered":"https:\/\/www.resist-cluster.de\/?page_id=33371"},"modified":"2024-12-05T10:44:25","modified_gmt":"2024-12-05T09:44:25","slug":"prof-dr-lars-doelken","status":"publish","type":"page","link":"https:\/\/www.resist-cluster.de\/en\/about-us\/research-team-2\/prof-dr-lars-doelken\/","title":{"rendered":"Prof. Dr. Lars D\u00f6lken"},"content":{"rendered":"

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Prof. Dr. Lars D\u00f6lken<\/p>\n<\/div>

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<\/i><\/td>\nMy Research Interest in RESIST<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/h1><\/div>

Our research at RESIST focuses on the cell biology of herpesvirus-host interactions and viral immune defense. We employ a broad range of systems biology approaches to identify and characterize the manipulation of the host transcriptional and translational machinery by HSV-1 and HCMV during productive infection, latency and reactivation. We have pioneered metabolic RNA labeling to study viral manipulation of their host cells with high temporal resolution at the single cell level and to uncover novel cellular genes and mechanisms that determine infection outcome. A long-term goal is to target conserved viral mechanisms that are important in early phases of lytic infection and virus reactivation in order to develop new antiviral agents with increased therapeutic potential.<\/p>\n<\/div>

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Lars D\u00f6lken<\/h1><\/div>
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Prof. Dr. Lars D\u00f6lken – Curriculum Vitae<\/h1><\/div>
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Current Position<\/h3><\/div>