{"id":11114,"date":"2020-07-14T13:18:19","date_gmt":"2020-07-14T11:18:19","guid":{"rendered":"https:\/\/www.resist-cluster.de\/?page_id=11114"},"modified":"2024-11-07T15:06:59","modified_gmt":"2024-11-07T14:06:59","slug":"prof-dr-michele-proietti","status":"publish","type":"page","link":"https:\/\/www.resist-cluster.de\/en\/about-us\/research-team-2\/prof-dr-michele-proietti\/","title":{"rendered":"Prof. Dr. Michele Proietti"},"content":{"rendered":"

<\/div>
<\/div>
<\/div>
<\/div>
<\/div>
<\/div>
<\/div><\/div><\/div>
<\/a><\/span><\/div>

Prof. Dr. Michele Proietti participates in RESIST research project A5<\/a>.<\/p>\n<\/div>

<\/div><\/div><\/div>

\n\n\n
<\/i><\/td>\nMy Research Interest in RESIST<\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/h1><\/div>
\n
\n
\n

Within RESIST we work in close collaboration with Professor Dr. Torsten Witte (MHH) and with Prof. Bodo Grimbacher (Institute for Immunodeficiency IFI, Center of Chronic Immunodeficiency, CCI, Uniklinikum Freiburg Freiburg). We are interested in identifying the genetic changes in our genome that can cause increased susceptibility to infections and immune-mediated pathology. I’am in particular interested in ADA2 and genes involved in the regulation of the nucleic acid sensing and type-I interferon response. Nucleic acid sensing and type-I interferon response are extraordinary instruments to protect the host from invading pathogens; however if not properly regulated their activation is at risk of triggering potentially life-threatening inflammation, as seen in auto-inflammatory syndromes and more recently in the outbreak of covid 19. Moreover, together with my cooperation partners in Freiburg I am currently developing a bioinformatics immunogenetic platform that integrates bioinformatics pipeline with a dedicated database for the analysis of genetic data in subjects with immune mediated diseases.\u00a0<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>

<\/div>
<\/div>
<\/div>
<\/i><\/span>Contact<\/span><\/a><\/div>
<\/div><\/div><\/div><\/div><\/div>
<\/path><\/svg><\/div>
<\/div><\/div><\/div>
<\/div><\/div><\/div><\/div><\/div>
<\/div>
<\/div>
<\/div>
<\/div>
<\/div><\/div><\/div>
<\/div><\/div><\/div>

Prof. Proietti<\/h1><\/div>
<\/span><\/div>
<\/div><\/div><\/div><\/div>
<\/div><\/div><\/div>
<\/div><\/div><\/div>
<\/div>
<\/div>
<\/div>
<\/div><\/div><\/div><\/div><\/div><\/div>
<\/path><\/svg><\/div>
<\/div><\/div><\/div>
<\/div><\/div><\/div><\/div><\/div>

Prof. Dr. Michele Proietti – Curriculum Vitae<\/h1><\/div>
<\/div><\/div><\/div>

Current Position<\/h3><\/div>