Prof. Dr. Kurt-Wolfram Sühs participates in RESIST research projects A3 and A4.
| My Research Interest in RESIST |
In RESIST our focus is on herpes viruses in particular the varicella zoster virus (VZV) that causes the most common viral neuroinfection called herpes zoster or shingles. Upon reactivation, VZV induces painful skin lesions and can in addition lead to severe complications like central nervous system affection or chronic neuropathic pain. Since the clinical manifestation of VZV infection varies tremendously between patients we aim to identify determinants for a complicated clinical course.
We pursue this by investigating clinical and genetic determinants and by searching for biomarkers in the cerebrospinal fluid of patients suffering from VZV. This information will give clues for a better understanding of the disease, for the clinical management of patients and may be the basis to identify new targets for the treatment of severe courses of VZV infections.
Prof. Sühs
Prof. Dr. Kurt-Wolfram Sühs and PD Dr. Frank Peßler
Prof. Dr. Kurt-Wolfram Sühs – Curriculum Vitae
Current Position
Undergraduate and Postgraduate Training
Academic and Research Posts
Awards and Prizes
Other Scientific Roles
10 Selected Publications (of > 92 original publications)
Schwenkenbecher P, Skripuletz T, Lange P, Durr M, Konen FF, Mohn N, Ringelstein M, Menge T, Friese MA, Melzer N, Malter MP, Hausler M, Thaler FS, Stangel M, Lewerenz J, Suhs KW. Intrathecal Antibody Production Against Epstein-Barr, Herpes Simplex, and Other Neurotropic Viruses in Autoimmune Encephalitis. Neurol Neuroimmunol Neuroinflamm 2021 November;8(6).
Mohn N, Grote-Levi L, Hopfner F, Eiz-Vesper B, Maecker-Kolhoff B, Warnke C, Suhs KW, Wattjes MP, Hoglinger GU, Skripuletz T. Innovative therapeutic concepts of progressive multifocal leukoencephalopathy. J Neurol 2022 May;269(5):2403-13.
Al-Mekhlafi A*, Suhs KW*, Schuchardt S, Kuhn M, Muller-Vahl K, Trebst C, Skripuletz T, Klawonn F, Stangel M, Pessler F. Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections. Cells 2021 May 6;10(5). *gleicher Beitrag
Muller-Vahl KR, Bindila L, Lutz B, Musshoff F, Skripuletz T, Baumgaertel C, Suhs KW. Cerebrospinal fluid endocannabinoid levels in Gilles de la Tourette syndrome. Neuropsychopharmacology 2020 July;45(8):1323-9.
Suhs KW, Novoselova N, Kuhn M, Seegers L, Kaever V, Muller-Vahl K, Trebst C, Skripuletz T, Stangel M, Pessler F. Kynurenine Is a Cerebrospinal Fluid Biomarker for Bacterial and Viral Central Nervous System Infections. J Infect Dis 2019 June 5;220(1):127-38.
Schwenkenbecher P, Wurster U, Suhs KW, Stangel M, Skripuletz T. Applying the 2017 McDonald diagnostic criteria for multiple sclerosis. Lancet Neurol 2018 June;17(6):498.
Kuhn M*, Suhs KW*, Akmatov MK, Klawonn F, Wang J, Skripuletz T, Kaever V, Stangel M, Pessler F. Mass-spectrometric profiling of cerebrospinal fluid reveals metabolite biomarkers for CNS involvement in varicella zoster virus reactivation. J Neuroinflammation 2018 January 17;15(1):20. *gleicher Beitrag
Suhs KW, Skripuletz T, Pul R, Alvermann S, Schwenkenbecher P, Stangel M, Muller-Vahl K. Gilles de la Tourette syndrome is not linked to contactin-associated protein receptor 2 antibodies. Mol Brain 2015 October 13;8(1):62.
Suhs KW, Fairless R, Williams SK, Heine K, Cavalie A, Diem R. N-methyl-D-aspartate receptor blockade is neuroprotective in experimental autoimmune optic neuritis. J Neuropathol Exp Neurol 2014 June;73(6):507-18.
Suhs KW, Hein K, Sattler MB, Gorlitz A, Ciupka C, Scholz K, Kasmann-Kellner B, Papanagiotou P, Schaffler N, Restemeyer C, Bittersohl D, Hassenstein A, Seitz B, Reith W, Fassbender K, Hilgers R, Heesen C, Bahr M, Diem R. A randomized, double-blind, phase 2 study of erythropoietin in optic neuritis. Ann Neurol 2012 August;72(2):199-210.
